The neuroprotective effect of modified Yeoldahanso-tang via autophagy enhancement in models of Parkinson's disease

Journal of Ethnopharmacology

Volumn 134, Issue 2, 2011, Pages 313-322

  Bae, Nayoung ^a,b   Ahn, Taekwon ^b   Chung, Sungkwon ^c   Oh, Myung Sook ^d   Ko, Hyeonseok ^a   Oh, Hyungun ^c   Park, Gunhyuk ^d   Yang, Hyun Ok ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Daejeon University   (South Korea)

^c Sungkyunkwan University   (South Korea)

^d Kyung Hee University   (South Korea)

Author keywords

1 Methyl 4 phenyl 1,2,3,6 tetrahydrophenylpyridine (MPTP); Autophagy; Lactacystin; Modified Youldahanso tang (MYH); Neuroprotection; Parkinson's disease

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; BECLIN 1; HERBACEOUS AGENT; LACTACYSTIN; MEMBRANE PROTEIN; MODIFIED YEOLDAHANSO TANG; NEUROPROTECTIVE AGENT; PROTEIN LIGHT CHAIN 3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGY; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DRUG MECHANISM; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PHEOCHROMOCYTOMA CELL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT; SUBSTANTIA NIGRA PARS COMPACTA;

1-METHYL-4-PHENYLPYRIDINIUM; ACETYLCYSTEINE; ANIMALS; AUTOPHAGY; BRAIN; CELL DIFFERENTIATION; DOPAMINE; MALE; MEDICINE, KOREAN TRADITIONAL; MICE; MICE, INBRED C57BL; NERVE GROWTH FACTOR; NEUROPROTECTIVE AGENTS; PARKINSON DISEASE; PC12 CELLS; PHYTOTHERAPY; PLANT EXTRACTS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEINS; RABBITS; RATS; UBIQUITIN;

ACORUS GRAMINEUS; ANGELICA TENUISSIMA; CIMICIFUGA HERACLEIFOLIA; DIMOCARPUS LONGAN; MUS; ORYCTOLAGUS CUNICULUS; PLATYCODON GRANDIFLORUM; POLYGALA TENUIFOLIA; PUERARIA MONTANA VAR. LOBATA; RAPHANUS SATIVUS; SCUTELLARIA BAICALENSIS;

EID: 79952696618     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.12.016     Document Type: Article

References (34)

1. Ara, J., Przedborski, S., Naini, A., Jackson-Lewis, V., Tri-letti, R., Ischiropoulos, H., 1998. Inactivation of tyrosine hydroxylase by nitration following exposure to peroxynitrite and 1-methy l-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP). Proceedings of the National Academy of Sciences of United States of America 95, 7659-7663.
2. Asanuma, M., Miyazaki, I., Ogwana, N., 2003. Dopamine- or l-DOPA-induced neurotoxicity: the role of dopamine quinone formation and tyrosinase in a model of Parkinson's disease. Neurotoxicity Research 5, 165-176.
3. Bandhyopadhyay, U., Cuervo, A.M., 2007. Chaperone-mediated autophagy in aging and neurodegeneration: lessons from alpha-synuclein. Experimental Gerontology 42, 120-128. (Pubitemid 44937825)
4. Blommaart, E.F., Krause, U., Schellens, J.P., Vreeling-Sindelarova, H., Meijer, A.J., 1997. The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes. European Journal of Biochemistry 243, 240-246. (Pubitemid 27060408)
5. Choi, J.S., Kim, K.Y., Kim, H.M., Ju, J.C., 2001. Studies on the cytokine production regulation in human astrocytes by Yeolda-Hanso Tang. Journal of Sasang Constitutional Medicine 13, 61-69.
6. Cuervo, A.M., Stefanis, L., Fredenburg, R., Lansbury, P.T., Sulzer, D., 2004. Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy. Science 305, 1292-1295. (Pubitemid 39129234)
7. Ding, Q., Dimayuga, E., Martin, S., Bruce-Keller, A.J., Nukala, V., Cuervo, A.M., Keller, J.N., 2003. Characterization of chronic low-level proteasome inhibition on neural homeostasis. Journal of Neurochemistry 86, 489-497. (Pubitemid 36842448)
8. Haavik, J., Toska, K., 1998. Tyrisine hydroxylase and Parkinson's disease. Molecular Neurobiology 16, 285-309.
9. Heikkila, R.E., Manzino, L., Cabbat, F.S., Duvoisi, R.C., 1984. Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine by monoamine oxidase inhibitors. Nature 311, 467-469.
10. Hershko, A., Ciechanover, A., 1998. The ubiquitin system. Annual Review of Biochemistry 67, 425-479. (Pubitemid 28411135)
11. Herve, A., Danie'le, B.F., Yvette, A., 2008. Disease-modifying drugs and Parkinson's disease. Progress in Neurobiology 84, 25-39.
12. Hurley, F.M., Costello, D.J., Sullivan, A.M., 2004. Neuroprotective effects of delayed administration of growth/differentiation factor-5 in the partial lesion model of Parkinson's disease. Experimental Neurology 185, 281-289. (Pubitemid 38084854)
13. Kabeya, Y., Mizushima, N., Ueno, T., Yamamoto, A., Kirisako, T., Noda, T., Kominami, E., Ohsumi, Y., Yoshimori, T., 2000. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. The EMBO Journal 19, 5720-5728.
14. Kay, D.M., Moran, D., Moses, L., 2007. Heterozygous parkin point mutations are as common in control subjects as in Parkinson's patients. Annals of Neurology 61, 47-54. (Pubitemid 46214243)
15. Kihara, A., Kabeya, Y., Ohsumi, Y., Yoshimori, T., 2001. Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network. EMBO Reports 2, 330-335. (Pubitemid 32401529)
16. Klionsky, D.J., Emr, S.D., 2000. Autophagy as a regulated pathway of cellular degradation. Science 290, 1717-1721. (Pubitemid 32004796)
17. Lee, J.H., Park, H.S., Kim, K.Y., 2002. Effects on Yeoldahanso Tang water extract on cultured primary hippocampal peroxide. Journal of Sasang Constitutional Medicine 14, 79-89.
18. Ma, J., Shaw, V.E., Mitrofanis, J., 2008. Dose melatonin help save dopaminergic cells in MPTP-treated mice? Parkinsonism & Related Disorders 13, 1-8.
19. Martinez-Vicente, M., Cuervo, A.M., 2007. Autophagy and neurodegeneration: when the cleaning crew goes on strike. Lancet Neurology 6, 352-361. (Pubitemid 46367949)
20. Massey, A.C., Kaushik, S., Sovak, G., Kif, R., Cuervo, A.M., 2006. Consequences of the selective blockage of chaperone-mediated autophagy. Proceedings of the National Academy of Sciences of United States of America 103, 5805-5810.
21. McNaught, K.S., Mytilineou, C., Jnobaptiste, R., Yabut, J., Shashidharan, P., Jenner, P., Olanow, C.W., 2002. Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures. Journal of Neurochemistry 81, 301-306. (Pubitemid 34809355)
22. McNaught, K.S., Olanow, C.W., 2003. Proteolytic stress: a unifying concept for the etiopathogenesis of Parkinson's disease. Annals of Neurology 53, S73-S84.
23. McNaught, K.S., Perl, D.P., Brownell, A.L., Olanow, C.W., 2004. Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease. Annals of Neurology 56, 149-162. (Pubitemid 38857373)
24. McNaught, K.S., Olanow, C.W., 2006. Protein aggregation in the pathogenesis of familial and sporadic Parkinson's disease. Neurobiology of Aging 27, 530-545. (Pubitemid 43290522)
25. Nagatsu, T., 1990. Change of tyrosine hydroxylase in the Parkinsonian brain and in the brain of MPTP-treated mice as revealed by homospecific activity. Neurochemical Research 15, 425-429. (Pubitemid 20198303)
26. Pan, T., Kondo, S., Zhu, W., Xie, W., Jankovic, J., Le, W., 2008. Neuroprotection of rapamycin in lactacystin-induced neurodegeneration via autophagy enhancement. Neurobiology of Disease 32, 16-25.
27. Park, S.J., Kim, H.S., Bae, Y.C., Lee, S.M., Kim, K.Y., Won, K.S., Shim, G.H., 2003. Influence of Yeolda-Hanso Tang on the hypoxic damage of cultured cerebral neurons from mouse and SK-N-MC cells. Journal of Sasang Constitutional Medicine 15, 72-89.
28. Polymeropoulos, M.H., Lavedan, C., Leroy, E., Ide, S.E., Dehejia, A., Dutra, A., 1997. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 276, 2045-2047. (Pubitemid 27443610)
29. Ramirez, A., Heimbach, A., Grundemann, J., Stiller, B., Hampshire, D., Cid, L.P., 2006. Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase. Nature Genetics 38, 1184-1191. (Pubitemid 44470365)
30. Mahesh, R., Kim, S.-J., 2009. The protective effects of insulin on hydrogen peroxide-induced oxidative stress in C6 glial cells. Biomolecules & Therapeutics 17, 395-402.
31. Seglen, P.O., Gordon, P.B., 1982. 3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes. Proceedings of the National Academy of Sciences of United States of America 79, 1889-1892. (Pubitemid 12088533)
32. Song, I.B., 2004. An introduction to Sasang Constitutional Medicine. Seoul, Jimoondang, 419-421p.
33. Takuya, O., Hayato, K., Ryohei, Y., Hironori, Y., Naoto, K., Hiroyuki, K., Tsutomu, A., 2009. Systemic administration of proteasome inhibitor protects against MPTP neurotoxicity in mice. Cellular and Molecular Neurobiology 29, 769-777.
34. Webb, J.L., Ravikumar, B., Atkins, J., Skepper, J.N., Rubinsztein, D.C., 2003. Alpha-synuclein is degraded by both autophagy and the proteasome. Journal of Biological Chemistry 278, 25009-25013. (Pubitemid 37548663)