메뉴 건너뛰기




Volumn 45, Issue 5, 2012, Pages 629-641

A Mammalian Autophagosome Maturation Mechanism Mediated by TECPR1 and the Atg12-Atg5 Conjugate

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY PROTEIN 12; AUTOPHAGY PROTEIN 5; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; PROTEIN; TECPR1 PROTEIN; UNCLASSIFIED DRUG;

EID: 84862777210     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2011.12.036     Document Type: Article
Times cited : (166)

References (61)
  • 1
    • 0033231275 scopus 로고    scopus 로고
    • Cytoplasm to vacuole trafficking of aminopeptidase I requires a t-SNARE-Sec1p complex composed of Tlg2p and Vps45p
    • Abeliovich H., Darsow T., Emr S.D. Cytoplasm to vacuole trafficking of aminopeptidase I requires a t-SNARE-Sec1p complex composed of Tlg2p and Vps45p. EMBO J. 1999, 18:6005-6016.
    • (1999) EMBO J. , vol.18 , pp. 6005-6016
    • Abeliovich, H.1    Darsow, T.2    Emr, S.D.3
  • 2
    • 39749141485 scopus 로고    scopus 로고
    • The regulation and function of Class III PI3Ks: novel roles for Vps34
    • Backer J.M. The regulation and function of Class III PI3Ks: novel roles for Vps34. Biochem. J. 2008, 410:1-17.
    • (2008) Biochem. J. , vol.410 , pp. 1-17
    • Backer, J.M.1
  • 3
    • 73449117508 scopus 로고    scopus 로고
    • Targeted deletion of autophagy-related 5 (atg5) impairs adipogenesis in a cellular model and in mice
    • Baerga R., Zhang Y., Chen P.H., Goldman S., Jin S. Targeted deletion of autophagy-related 5 (atg5) impairs adipogenesis in a cellular model and in mice. Autophagy 2009, 5:1118-1130.
    • (2009) Autophagy , vol.5 , pp. 1118-1130
    • Baerga, R.1    Zhang, Y.2    Chen, P.H.3    Goldman, S.4    Jin, S.5
  • 4
    • 40449106780 scopus 로고    scopus 로고
    • Impaired phagosomal maturation in neutrophils leads to periodontitis in lysosomal-associated membrane protein-2 knockout mice
    • Beertsen W., Willenborg M., Everts V., Zirogianni A., Podschun R., Schroder B., Eskelinen E.L., Saftig P. Impaired phagosomal maturation in neutrophils leads to periodontitis in lysosomal-associated membrane protein-2 knockout mice. J. Immunol. 2008, 180:475-482.
    • (2008) J. Immunol. , vol.180 , pp. 475-482
    • Beertsen, W.1    Willenborg, M.2    Everts, V.3    Zirogianni, A.4    Podschun, R.5    Schroder, B.6    Eskelinen, E.L.7    Saftig, P.8
  • 5
    • 77954237882 scopus 로고    scopus 로고
    • Network organization of the human autophagy system
    • Behrends C., Sowa M.E., Gygi S.P., Harper J.W. Network organization of the human autophagy system. Nature 2010, 466:68-76.
    • (2010) Nature , vol.466 , pp. 68-76
    • Behrends, C.1    Sowa, M.E.2    Gygi, S.P.3    Harper, J.W.4
  • 7
    • 79954577494 scopus 로고    scopus 로고
    • Vacuolization of mucolipidosis type II mouse exocrine gland cells represents accumulation of autolysosomes
    • Boonen M., van Meel E., Oorschot V., Klumperman J., Kornfeld S. Vacuolization of mucolipidosis type II mouse exocrine gland cells represents accumulation of autolysosomes. Mol. Biol. Cell 2011, 22:1135-1147.
    • (2011) Mol. Biol. Cell , vol.22 , pp. 1135-1147
    • Boonen, M.1    van Meel, E.2    Oorschot, V.3    Klumperman, J.4    Kornfeld, S.5
  • 11
    • 0030807624 scopus 로고    scopus 로고
    • A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole
    • Darsow T., Rieder S.E., Emr S.D. A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole. J. Cell Biol. 1997, 138:517-529.
    • (1997) J. Cell Biol. , vol.138 , pp. 517-529
    • Darsow, T.1    Rieder, S.E.2    Emr, S.D.3
  • 12
    • 0034306455 scopus 로고    scopus 로고
    • Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities
    • Dowler S., Currie R.A., Campbell D.G., Deak M., Kular G., Downes C.P., Alessi D.R. Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities. Biochem. J. 2000, 351:19-31.
    • (2000) Biochem. J. , vol.351 , pp. 19-31
    • Dowler, S.1    Currie, R.A.2    Campbell, D.G.3    Deak, M.4    Kular, G.5    Downes, C.P.6    Alessi, D.R.7
  • 13
    • 26844531363 scopus 로고    scopus 로고
    • Maturation of autophagic vacuoles in Mammalian cells
    • Eskelinen E.L. Maturation of autophagic vacuoles in Mammalian cells. Autophagy 2005, 1:1-10.
    • (2005) Autophagy , vol.1 , pp. 1-10
    • Eskelinen, E.L.1
  • 15
    • 79956358522 scopus 로고    scopus 로고
    • Autophagosome targeting and membrane curvature sensing by Barkor/Atg14(L)
    • Fan W., Nassiri A., Zhong Q. Autophagosome targeting and membrane curvature sensing by Barkor/Atg14(L). Proc. Natl. Acad. Sci. USA 2011, 108:7769-7774.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 7769-7774
    • Fan, W.1    Nassiri, A.2    Zhong, Q.3
  • 16
    • 43949143804 scopus 로고    scopus 로고
    • The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy
    • Fujita N., Itoh T., Omori H., Fukuda M., Noda T., Yoshimori T. The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. Mol. Biol. Cell 2008, 19:2092-2100.
    • (2008) Mol. Biol. Cell , vol.19 , pp. 2092-2100
    • Fujita, N.1    Itoh, T.2    Omori, H.3    Fukuda, M.4    Noda, T.5    Yoshimori, T.6
  • 17
    • 77953543377 scopus 로고    scopus 로고
    • The Beclin 1-VPS34 complex-at the crossroads of autophagy and beyond
    • Funderburk S.F., Wang Q.J., Yue Z. The Beclin 1-VPS34 complex-at the crossroads of autophagy and beyond. Trends Cell Biol. 2010, 20:355-362.
    • (2010) Trends Cell Biol. , vol.20 , pp. 355-362
    • Funderburk, S.F.1    Wang, Q.J.2    Yue, Z.3
  • 18
    • 3242877218 scopus 로고    scopus 로고
    • Rab7 is required for the normal progression of the autophagic pathway in mammalian cells
    • Gutierrez M.G., Munafo D.B., Beron W., Colombo M.I. Rab7 is required for the normal progression of the autophagic pathway in mammalian cells. J. Cell Sci. 2004, 117:2687-2697.
    • (2004) J. Cell Sci. , vol.117 , pp. 2687-2697
    • Gutierrez, M.G.1    Munafo, D.B.2    Beron, W.3    Colombo, M.I.4
  • 21
    • 0032404028 scopus 로고    scopus 로고
    • Enhancement of phosphoinositide 3-kinase (PI 3-kinase) activity by membrane curvature and inositol-phospholipid-binding peptides
    • Hubner S., Couvillon A.D., Kas J.A., Bankaitis V.A., Vegners R., Carpenter C.L., Janmey P.A. Enhancement of phosphoinositide 3-kinase (PI 3-kinase) activity by membrane curvature and inositol-phospholipid-binding peptides. Eur. J. Biochem. 1998, 258:846-853.
    • (1998) Eur. J. Biochem. , vol.258 , pp. 846-853
    • Hubner, S.1    Couvillon, A.D.2    Kas, J.A.3    Bankaitis, V.A.4    Vegners, R.5    Carpenter, C.L.6    Janmey, P.A.7
  • 22
    • 77956179625 scopus 로고    scopus 로고
    • Regulation of macroautophagy in Saccharomyces cerevisiae
    • Inoue Y., Klionsky D.J. Regulation of macroautophagy in Saccharomyces cerevisiae. Semin. Cell Dev. Biol. 2010, 21:664-670.
    • (2010) Semin. Cell Dev. Biol. , vol.21 , pp. 664-670
    • Inoue, Y.1    Klionsky, D.J.2
  • 26
    • 0033791650 scopus 로고    scopus 로고
    • Autophagy, cytoplasm-to-vacuole targeting pathway, and pexophagy in yeast and mammalian cells
    • Kim J., Klionsky D.J. Autophagy, cytoplasm-to-vacuole targeting pathway, and pexophagy in yeast and mammalian cells. Annu. Rev. Biochem. 2000, 69:303-342.
    • (2000) Annu. Rev. Biochem. , vol.69 , pp. 303-342
    • Kim, J.1    Klionsky, D.J.2
  • 27
    • 34548077575 scopus 로고    scopus 로고
    • Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3
    • Kimura S., Noda T., Yoshimori T. Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3. Autophagy 2007, 3:452-460.
    • (2007) Autophagy , vol.3 , pp. 452-460
    • Kimura, S.1    Noda, T.2    Yoshimori, T.3
  • 28
    • 59349105233 scopus 로고    scopus 로고
    • Monitoring autophagy in mammalian cultured cells through the dynamics of LC3
    • Kimura S., Fujita N., Noda T., Yoshimori T. Monitoring autophagy in mammalian cultured cells through the dynamics of LC3. Methods Enzymol. 2009, 452:1-12.
    • (2009) Methods Enzymol. , vol.452 , pp. 1-12
    • Kimura, S.1    Fujita, N.2    Noda, T.3    Yoshimori, T.4
  • 30
    • 0033747489 scopus 로고    scopus 로고
    • Autophagy in the epithelial cells of murine seminal vesicle in vitro. Formation of large sheets of nascent isolation membranes, sequestration of the nucleus and inhibition by wortmannin and 3-ethyladenine
    • Kovacs A.L., Rez G., Palfia Z., Kovacs J. Autophagy in the epithelial cells of murine seminal vesicle in vitro. Formation of large sheets of nascent isolation membranes, sequestration of the nucleus and inhibition by wortmannin and 3-ethyladenine. Cell Tissue Res. 2000, 302:253-261.
    • (2000) Cell Tissue Res. , vol.302 , pp. 253-261
    • Kovacs, A.L.1    Rez, G.2    Palfia, Z.3    Kovacs, J.4
  • 31
    • 0037166241 scopus 로고    scopus 로고
    • Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast
    • Kuma A., Mizushima N., Ishihara N., Ohsumi Y. Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast. J. Biol. Chem. 2002, 277:18619-18625.
    • (2002) J. Biol. Chem. , vol.277 , pp. 18619-18625
    • Kuma, A.1    Mizushima, N.2    Ishihara, N.3    Ohsumi, Y.4
  • 33
    • 34548492271 scopus 로고    scopus 로고
    • ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration
    • Lee J.A., Beigneux A., Ahmad S.T., Young S.G., Gao F.B. ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration. Curr. Biol. 2007, 17:1561-1567.
    • (2007) Curr. Biol. , vol.17 , pp. 1561-1567
    • Lee, J.A.1    Beigneux, A.2    Ahmad, S.T.3    Young, S.G.4    Gao, F.B.5
  • 34
    • 70349768075 scopus 로고    scopus 로고
    • A small molecule inhibitor of inducible heat shock protein 70
    • Leu J.I., Pimkina J., Frank A., Murphy M.E., George D.L. A small molecule inhibitor of inducible heat shock protein 70. Mol. Cell 2009, 36:15-27.
    • (2009) Mol. Cell , vol.36 , pp. 15-27
    • Leu, J.I.1    Pimkina, J.2    Frank, A.3    Murphy, M.E.4    George, D.L.5
  • 35
    • 1842583789 scopus 로고    scopus 로고
    • Development by self-digestion: molecular mechanisms and biological functions of autophagy
    • Levine B., Klionsky D.J. Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev. Cell 2004, 6:463-477.
    • (2004) Dev. Cell , vol.6 , pp. 463-477
    • Levine, B.1    Klionsky, D.J.2
  • 36
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine B., Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008, 132:27-42.
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 42
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • Mizushima N., Levine B., Cuervo A.M., Klionsky D.J. Autophagy fights disease through cellular self-digestion. Nature 2008, 451:1069-1075.
    • (2008) Nature , vol.451 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 43
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • Mizushima N., Yoshimori T., Levine B. Methods in mammalian autophagy research. Cell 2010, 140:313-326.
    • (2010) Cell , vol.140 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 44
    • 79960774898 scopus 로고    scopus 로고
    • Autophagosome precursor maturation requires homotypic fusion
    • Moreau K., Ravikumar B., Renna M., Puri C., Rubinsztein D.C. Autophagosome precursor maturation requires homotypic fusion. Cell 2011, 146:303-317.
    • (2011) Cell , vol.146 , pp. 303-317
    • Moreau, K.1    Ravikumar, B.2    Renna, M.3    Puri, C.4    Rubinsztein, D.C.5
  • 47
  • 50
    • 0019866088 scopus 로고
    • Effect of weak bases on the intralysosomal pH in mouse peritoneal macrophages
    • Poole B., Ohkuma S. Effect of weak bases on the intralysosomal pH in mouse peritoneal macrophages. J. Cell Biol. 1981, 90:665-669.
    • (1981) J. Cell Biol. , vol.90 , pp. 665-669
    • Poole, B.1    Ohkuma, S.2
  • 51
    • 57049094929 scopus 로고    scopus 로고
    • Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease
    • Raben N., Hill V., Shea L., Takikita S., Baum R., Mizushima N., Ralston E., Plotz P. Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease. Hum. Mol. Genet. 2008, 17:3897-3908.
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 3897-3908
    • Raben, N.1    Hill, V.2    Shea, L.3    Takikita, S.4    Baum, R.5    Mizushima, N.6    Ralston, E.7    Plotz, P.8
  • 52
    • 65349155174 scopus 로고    scopus 로고
    • Early endosomes and endosomal coatomer are required for autophagy
    • Razi M., Chan E.Y., Tooze S.A. Early endosomes and endosomal coatomer are required for autophagy. J. Cell Biol. 2009, 185:305-321.
    • (2009) J. Cell Biol. , vol.185 , pp. 305-321
    • Razi, M.1    Chan, E.Y.2    Tooze, S.A.3
  • 54
    • 70349919804 scopus 로고    scopus 로고
    • Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes
    • Simonsen A., Tooze S.A. Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes. J. Cell Biol. 2009, 186:773-782.
    • (2009) J. Cell Biol. , vol.186 , pp. 773-782
    • Simonsen, A.1    Tooze, S.A.2
  • 55
    • 58049192897 scopus 로고    scopus 로고
    • Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase
    • Sun Q., Fan W., Chen K., Ding X., Chen S., Zhong Q. Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase. Proc. Natl. Acad. Sci. USA 2008, 105:19211-19216.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 19211-19216
    • Sun, Q.1    Fan, W.2    Chen, K.3    Ding, X.4    Chen, S.5    Zhong, Q.6
  • 57
    • 78650936005 scopus 로고    scopus 로고
    • The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression
    • Sun Q., Zhang J., Fan W., Wong K.N., Ding X., Chen S., Zhong Q. The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression. J. Biol. Chem. 2011, 286:185-191.
    • (2011) J. Biol. Chem. , vol.286 , pp. 185-191
    • Sun, Q.1    Zhang, J.2    Fan, W.3    Wong, K.N.4    Ding, X.5    Chen, S.6    Zhong, Q.7
  • 58
    • 77956924900 scopus 로고    scopus 로고
    • Selective transport of alpha-mannosidase by autophagic pathways: identification of a novel receptor, Atg34p
    • Suzuki K., Kondo C., Morimoto M., Ohsumi Y. Selective transport of alpha-mannosidase by autophagic pathways: identification of a novel receptor, Atg34p. J. Biol. Chem. 2010, 285:30019-30025.
    • (2010) J. Biol. Chem. , vol.285 , pp. 30019-30025
    • Suzuki, K.1    Kondo, C.2    Morimoto, M.3    Ohsumi, Y.4
  • 61
    • 0032168684 scopus 로고    scopus 로고
    • Phosphoinositide signaling and turnover: PtdIns(3)P, a regulator of membrane traffic, is transported to the vacuole and degraded by a process that requires lumenal vacuolar hydrolase activities
    • Wurmser A.E., Emr S.D. Phosphoinositide signaling and turnover: PtdIns(3)P, a regulator of membrane traffic, is transported to the vacuole and degraded by a process that requires lumenal vacuolar hydrolase activities. EMBO J. 1998, 17:4930-4942.
    • (1998) EMBO J. , vol.17 , pp. 4930-4942
    • Wurmser, A.E.1    Emr, S.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.