Nuclear envelope alterations generate an aging-like epigenetic pattern in mice deficient in Zmpste24 metalloprotease

Aging Cell

Volumn 9, Issue 6, 2010, Pages 947-957

  Osorio, Fernando G ^a   Varela, Ignacio ^a   Lara, Ester ^b   Puente, Xose S ^a   Espada, Jesús ^c   Santoro, Raffaella ^d   Freije, José M P ^a   Fraga, Mario F ^e   López Otín, Carlos ^a  

^a DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

^b UNIVERSITY OF OVIEDO   (Spain)

^c INSTITUTO DE INVESTIGACIONES BIOMÉDICAS ALBERTO SOLS   (Spain)

^d UNIVERSITY OF ZURICH   (Switzerland)

^e CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

Author keywords

Aging; Histone acetylation; Lamina; Methylation; Progeria; Proteolysis

Indexed keywords

HISTONE H2B; HISTONE H4; METALLOPROTEINASE; RIBOSOME DNA;

ACETYLATION; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS MEMBRANE; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA METHYLATION; EPIGENETICS; GENE CONTROL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROGERIA; PROTEIN DEGRADATION; RNA SEQUENCE;

ANIMALIA; MUS; RODENTIA;

EID: 78249271058     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2010.00621.x     Document Type: Article

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