Targeting the unfolded protein response in disease

Nature Reviews Drug Discovery

Volumn 12, Issue 9, 2013, Pages 703-719

  Hetz, Claudio ^a,b   Chevet, Eric ^c   Harding, Heather P ^d  

^a UNIVERSITY OF CHILE   (Chile)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c UNIVERSITÉ DE BORDEAUX   (France)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; APOPTOSIS SIGNAL REGULATING KINASE 1; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BORTEZOMIB; DBEQ; EEYARESTATIN; GSK 2606414; GSK 2656157; GSK2606414; GSK2656157; MAL3 101; MKC 3946; ML 240; ML240; RADICICOL; RNA; SORAFENIB; STF 083010; STRESS ACTIVATED PROTEIN KINASE; SUNITINIB; TANESPIMYCIN; TOYOCAMYCIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; UNCLASSIFIED DRUG;

APOPTOSIS; AUTOIMMUNE DISEASE; DEGENERATIVE DISEASE; DIABETES MELLITUS; DRUG STRUCTURE; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; GENE TARGETING; HUMAN; LIVER DISEASE; NEOPLASM; OBESITY; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN SYNTHESIS; PROTEIN TARGETING; REVIEW; RNA INTERFERENCE; SECRETORY CELL; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE;

ANIMALS; APOPTOSIS; DRUG DESIGN; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; HUMANS; MOLECULAR TARGETED THERAPY; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE;

EID: 84883387793     PISSN: 14741776     EISSN: 14741784     Source Type: Journal    
DOI: 10.1038/nrd3976     Document Type: Review

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