-
1
-
-
0028793257
-
Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
-
Ankarcrona M, Dypbukt JM, Bonfoco E, Zhivotovsky B, Orrenius S, Lipton SA, Nicotera P (1995) Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron 15:961-973.
-
(1995)
Neuron
, vol.15
, pp. 961-973
-
-
Ankarcrona, M.1
Dypbukt, J.M.2
Bonfoco, E.3
Zhivotovsky, B.4
Orrenius, S.5
Lipton, S.A.6
Nicotera, P.7
-
2
-
-
0033782015
-
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
-
Bertolotti A, Zhan Y, Hendershot LM, Harding HP, Ron D (2000) Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response. Nat Cell Biol 2:326-332.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 326-332
-
-
Bertolotti, A.1
Zhan, Y.2
Hendershot, L.M.3
Harding, H.P.4
Ron, D.5
-
3
-
-
33645154135
-
Cellular response to endoplasmic reticulum stress: A matter of life or death
-
Boyce M, Yuan J (2006) Cellular response to endoplasmic reticulum stress: a matter of life or death. Cell Death Differ 13:363-373.
-
(2006)
Cell Death Differ
, vol.13
, pp. 363-373
-
-
Boyce, M.1
Yuan, J.2
-
4
-
-
13644256191
-
A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress
-
Boyce M, Bryant KF, Jousse C, Long K, Harding HP, Scheuner D, Kaufman RJ, Ma D, Coen DM, Ron D, Yuan J (2005) A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress. Science 307:935-939.
-
(2005)
Science
, vol.307
, pp. 935-939
-
-
Boyce, M.1
Bryant, K.F.2
Jousse, C.3
Long, K.4
Harding, H.P.5
Scheuner, D.6
Kaufman, R.J.7
Ma, D.8
Coen, D.M.9
Ron, D.10
Yuan, J.11
-
5
-
-
0346250162
-
Regulation of apoptosis by endoplasmic reticulum pathways
-
Breckenridge DG, Germain M, Mathai JP, Nguyen M, Shore GC (2003) Regulation of apoptosis by endoplasmic reticulum pathways. Oncogene 22:8608-8618.
-
(2003)
Oncogene
, vol.22
, pp. 8608-8618
-
-
Breckenridge, D.G.1
Germain, M.2
Mathai, J.P.3
Nguyen, M.4
Shore, G.C.5
-
6
-
-
0035736259
-
Organelle-specific initiation of cell death pathways
-
Ferri KF, Kroemer G (2001) Organelle-specific initiation of cell death pathways. Nat Cell Biol 3:255-263.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 255-263
-
-
Ferri, K.F.1
Kroemer, G.2
-
7
-
-
0036791560
-
Caspase-12 processing and fragment translocation into nuclei of tunicamycin-treated cells
-
Fujita E, Kouroku Y, Jimbo A, Isoai A, Maruyama K, Momoi T (2002) Caspase-12 processing and fragment translocation into nuclei of tunicamycin-treated cells. Cell Death Differ 9:1108-1114.
-
(2002)
Cell Death Differ
, vol.9
, pp. 1108-1114
-
-
Fujita, E.1
Kouroku, Y.2
Jimbo, A.3
Isoai, A.4
Maruyama, K.5
Momoi, T.6
-
9
-
-
33646237823
-
Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha
-
Hetz C, Bernasconi P, Fisher J, Lee AH, Bassik MC, Antonsson B, Brandt GS, Iwakoshi NN, Schinzel A, Glimcher LH, Korsmeyer SJ (2006) Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha. Science 312:572-576.
-
(2006)
Science
, vol.312
, pp. 572-576
-
-
Hetz, C.1
Bernasconi, P.2
Fisher, J.3
Lee, A.H.4
Bassik, M.C.5
Antonsson, B.6
Brandt, G.S.7
Iwakoshi, N.N.8
Schinzel, A.9
Glimcher, L.H.10
Korsmeyer, S.J.11
-
10
-
-
0033965979
-
Intracerebral injection of caspase-3 inhibitor prevents neuronal apoptosis after kainic acid-evoked status epilepticus
-
Kondratyev A, Gale K (2000) Intracerebral injection of caspase-3 inhibitor prevents neuronal apoptosis after kainic acid-evoked status epilepticus. Brain Res Mol Brain Res 75:216-224.
-
(2000)
Brain Res Mol Brain Res
, vol.75
, pp. 216-224
-
-
Kondratyev, A.1
Gale, K.2
-
11
-
-
0035118969
-
Regulation of X-chromosome-linked inhibitor of apoptosis protein in kainic acid-induced neuronal death in the rat hippocampus
-
Korhonen L, Belluardo N, Lindholm D (2001) Regulation of X-chromosome-linked inhibitor of apoptosis protein in kainic acid-induced neuronal death in the rat hippocampus. Mol Cell Neurosci 17:364-372.
-
(2001)
Mol Cell Neurosci
, vol.17
, pp. 364-372
-
-
Korhonen, L.1
Belluardo, N.2
Lindholm, D.3
-
12
-
-
0141836884
-
Increase in Bcl-2 phosphorylation and reduced levels of BH3-only Bcl-2 family proteins in kainic acid-mediated neuronal death in the rat brain
-
Korhonen L, Belluardo N, Mudo G, Lindholm D (2003) Increase in Bcl-2 phosphorylation and reduced levels of BH3-only Bcl-2 family proteins in kainic acid-mediated neuronal death in the rat brain. Eur J Neurosci 18:1121-1134.
-
(2003)
Eur J Neurosci
, vol.18
, pp. 1121-1134
-
-
Korhonen, L.1
Belluardo, N.2
Mudo, G.3
Lindholm, D.4
-
13
-
-
1842850749
-
Differential regulation of X-chromosome-linked inhibitor of apoptosis protein (XIAP) and caspase-3 by NMDA in developing hippocampal neurons; involvement of the mitochondrial pathway in NMDA-mediated neuronal survival
-
Korhonen L, Näpänkangas U, Steen H, Chen Y, Martinez R, Lindholm D (2004) Differential regulation of X-chromosome-linked inhibitor of apoptosis protein (XIAP) and caspase-3 by NMDA in developing hippocampal neurons; involvement of the mitochondrial pathway in NMDA-mediated neuronal survival. Exp Cell Res 295:290-299.
-
(2004)
Exp Cell Res
, vol.295
, pp. 290-299
-
-
Korhonen, L.1
Näpänkangas, U.2
Steen, H.3
Chen, Y.4
Martinez, R.5
Lindholm, D.6
-
14
-
-
10644224471
-
Hippocalcin protects against caspase-12-induced and age-dependent neuronal degeneration
-
Korhonen L, Hansson I, Kukkonen JP, Brännvall K, Kobayashi M, Takamatsu K, Lindholm D (2005) Hippocalcin protects against caspase-12-induced and age-dependent neuronal degeneration. Mol Cell Neurosci 28:85-95.
-
(2005)
Mol Cell Neurosci
, vol.28
, pp. 85-95
-
-
Korhonen, L.1
Hansson, I.2
Kukkonen, J.P.3
Brännvall, K.4
Kobayashi, M.5
Takamatsu, K.6
Lindholm, D.7
-
15
-
-
0037083755
-
IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response
-
Lee K, Tirasophon W, Shen X, Michalak M, Prywes R, Okada T, Yoshida H, Mori K, Kaufman RJ (2002) IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response. Genes Dev 16:452-466.
-
(2002)
Genes Dev
, vol.16
, pp. 452-466
-
-
Lee, K.1
Tirasophon, W.2
Shen, X.3
Michalak, M.4
Prywes, R.5
Okada, T.6
Yoshida, H.7
Mori, K.8
Kaufman, R.J.9
-
16
-
-
0035433420
-
Four deaths and a funeral: From caspases to alternative mechanisms
-
Leist M, Jäättelä M (2001) Four deaths and a funeral: from caspases to alternative mechanisms. Nat Rev Mol Cell Biol 2:589-598.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 589-598
-
-
Leist, M.1
Jäättelä, M.2
-
17
-
-
0038380386
-
Roles and rules of kainate receptors in synaptic transmission
-
Lerma J (2003) Roles and rules of kainate receptors in synaptic transmission. Nat Rev Neurosci 4:481-495.
-
(2003)
Nat Rev Neurosci
, vol.4
, pp. 481-495
-
-
Lerma, J.1
-
20
-
-
0038043221
-
Structure and intermolecular interactions of the luminal dimerization domain of human IRE1alpha
-
Liu CY, Xu Z, Kaufman RJ (2003) Structure and intermolecular interactions of the luminal dimerization domain of human IRE1alpha. J Biol Chem 278:17680-17687.
-
(2003)
J Biol Chem
, vol.278
, pp. 17680-17687
-
-
Liu, C.Y.1
Xu, Z.2
Kaufman, R.J.3
-
21
-
-
0344915157
-
Bcl-2, Bax and Bcl-x expression following kainic acid administration at convulsant doses in the rat
-
Lopez E, Pozas E, Rivera R, Ferrer I (1999) Bcl-2, Bax and Bcl-x expression following kainic acid administration at convulsant doses in the rat. Neuroscience 91:1461-1470.
-
(1999)
Neuroscience
, vol.91
, pp. 1461-1470
-
-
Lopez, E.1
Pozas, E.2
Rivera, R.3
Ferrer, I.4
-
22
-
-
0037166237
-
Dimerization and release of molecular chaperone inhibition facilitate activation of eukaryotic initiation factor-2 kinase in response to endoplasmic reticulum stress
-
Ma K, Vattem KM, Wek RC (2002) Dimerization and release of molecular chaperone inhibition facilitate activation of eukaryotic initiation factor-2 kinase in response to endoplasmic reticulum stress. J Biol Chem 277:18728-18735.
-
(2002)
J Biol Chem
, vol.277
, pp. 18728-18735
-
-
Ma, K.1
Vattem, K.M.2
Wek, R.C.3
-
23
-
-
0035144493
-
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state
-
McCullough KD, Martindale JL, Klotz LO, Aw TY, Holbrook NJ (2001) Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol Cell Biol 21:1249-1259.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 1249-1259
-
-
McCullough, K.D.1
Martindale, J.L.2
Klotz, L.O.3
Aw, T.Y.4
Holbrook, N.J.5
-
24
-
-
0029437258
-
Seizures increase trkC mRNA expression in the dentate gyrus of rat hippocampus. Role of glutamate receptor activation
-
Mudo G, Salin T, Condorelli DF, Jiang XH, Dell'Albani P, Timmusk T, Metsis M, Funakoshi H, Belluardo N (1995) Seizures increase trkC mRNA expression in the dentate gyrus of rat hippocampus. Role of glutamate receptor activation. J Mol Neurosci 6:11-22.
-
(1995)
J Mol Neurosci
, vol.6
, pp. 11-22
-
-
Mudo, G.1
Salin, T.2
Condorelli, D.F.3
Jiang, X.H.4
Dell'Albani, P.5
Timmusk, T.6
Metsis, M.7
Funakoshi, H.8
Belluardo, N.9
-
25
-
-
0017844923
-
Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells
-
Nadler JV, Perry BW, Cotman CW (1978) Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells. Nature 271:676-677.
-
(1978)
Nature
, vol.271
, pp. 676-677
-
-
Nadler, J.V.1
Perry, B.W.2
Cotman, C.W.3
-
26
-
-
0034698878
-
Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis
-
Nakagawa T, Yuan J (2000) Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis. J Cell Biol 150:887-894.
-
(2000)
J Cell Biol
, vol.150
, pp. 887-894
-
-
Nakagawa, T.1
Yuan, J.2
-
27
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
-
Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA, Yuan J (2000) Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 403:98-103.
-
(2000)
Nature
, vol.403
, pp. 98-103
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
Li, E.4
Xu, J.5
Yankner, B.A.6
Yuan, J.7
-
28
-
-
23844481790
-
Caspase-12 and caspase-4 are not required for caspase-dependent endoplasmic reticulum stress-induced apoptosis
-
Obeng EA, Boise LH (2005) Caspase-12 and caspase-4 are not required for caspase-dependent endoplasmic reticulum stress-induced apoptosis. J Biol Chem 280:29578-29587.
-
(2005)
J Biol Chem
, vol.280
, pp. 29578-29587
-
-
Obeng, E.A.1
Boise, L.H.2
-
29
-
-
0016230519
-
Kainic acid: A powerful neurotoxic analogue of glutamate
-
Olney JW, Rhee V, Ho OL (1974) Kainic acid: a powerful neurotoxic analogue of glutamate. Brain Res 77:507-512.
-
(1974)
Brain Res
, vol.77
, pp. 507-512
-
-
Olney, J.W.1
Rhee, V.2
Ho, O.L.3
-
30
-
-
1842843860
-
Coupling endoplasmic reticulum stress to the cell death program
-
Rao RV, Ellerby HM, Bredesen DE (2004) Coupling endoplasmic reticulum stress to the cell death program. Cell Death Differ 11:372-380.
-
(2004)
Cell Death Differ
, vol.11
, pp. 372-380
-
-
Rao, R.V.1
Ellerby, H.M.2
Bredesen, D.E.3
-
31
-
-
13844253258
-
Fluoro-Jade C results in ultra high resolution and contrast laeling of degenerating neurons
-
Schmued LC, Stowers CC, Scallet AC, Xu L (2005) Fluoro-Jade C results in ultra high resolution and contrast laeling of degenerating neurons. Brain Res 1035:24-31.
-
(2005)
Brain Res
, vol.1035
, pp. 24-31
-
-
Schmued, L.C.1
Stowers, C.C.2
Scallet, A.C.3
Xu, L.4
-
32
-
-
27744478660
-
Bruce/apollon promotes hippocampal neuron survival and is downregulated by kainic acid
-
Sokka AL, Mudo G, Aaltonen J, Belluardo N, Lindholm D, Korhonen L (2005) Bruce/apollon promotes hippocampal neuron survival and is downregulated by kainic acid. Biochem Biophys Res Commun 338:729-735.
-
(2005)
Biochem Biophys Res Commun
, vol.338
, pp. 729-735
-
-
Sokka, A.L.1
Mudo, G.2
Aaltonen, J.3
Belluardo, N.4
Lindholm, D.5
Korhonen, L.6
-
33
-
-
33744998954
-
Glucocorticoid hormones decrease proliferation of embryonic neural stem cells through ubiquitin-mediated degradation of cyclin D1
-
Sundberg M, Savola S, Hienola A, Korhonen L, Lindholm D (2006) Glucocorticoid hormones decrease proliferation of embryonic neural stem cells through ubiquitin-mediated degradation of cyclin D1. J Neurosci 26:5402-5410.
-
(2006)
J Neurosci
, vol.26
, pp. 5402-5410
-
-
Sundberg, M.1
Savola, S.2
Hienola, A.3
Korhonen, L.4
Lindholm, D.5
-
34
-
-
0034723235
-
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
-
Urano F, Wang X, Bertolotti A, Zhang Y, Chung P, Harding HP, Ron D (2000) Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science 287:664-666.
-
(2000)
Science
, vol.287
, pp. 664-666
-
-
Urano, F.1
Wang, X.2
Bertolotti, A.3
Zhang, Y.4
Chung, P.5
Harding, H.P.6
Ron, D.7
-
35
-
-
12944314765
-
Physiology and pathophysiology of the calcium store in the endoplasmic reticulum of neurons
-
Verkhratsky A (2005) Physiology and pathophysiology of the calcium store in the endoplasmic reticulum of neurons. Physiol Rev 85:201-279.
-
(2005)
Physiol Rev
, vol.85
, pp. 201-279
-
-
Verkhratsky, A.1
-
36
-
-
4143152796
-
Caspase-12 cleavage and increased oxidative stress during motoneuron degeneration in transgenic mouse model of ALS
-
Wootz H, Hansson I, Korhonen L, Näpänkangas U, Lindholm D (2004) Caspase-12 cleavage and increased oxidative stress during motoneuron degeneration in transgenic mouse model of ALS. Biochem Biophys Res Commun 322:281-326.
-
(2004)
Biochem Biophys Res Commun
, vol.322
, pp. 281-326
-
-
Wootz, H.1
Hansson, I.2
Korhonen, L.3
Näpänkangas, U.4
Lindholm, D.5
-
37
-
-
33645156429
-
From acute ER stress to physiological roles of the unfolded protein response
-
Wu J, Kaufman RJ (2006) From acute ER stress to physiological roles of the unfolded protein response. Cell Death Differ 13:374-384.
-
(2006)
Cell Death Differ
, vol.13
, pp. 374-384
-
-
Wu, J.1
Kaufman, R.J.2
-
38
-
-
0030780804
-
Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene
-
Yang DD, Kuan CY, Whitmarsh AJ, Rincon M, Zheng TS, Davis RJ, Rakic P, Flavell RA (1997) Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene. Nature 389:865-870.
-
(1997)
Nature
, vol.389
, pp. 865-870
-
-
Yang, D.D.1
Kuan, C.Y.2
Whitmarsh, A.J.3
Rincon, M.4
Zheng, T.S.5
Davis, R.J.6
Rakic, P.7
Flavell, R.A.8
-
39
-
-
0033015485
-
The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: Suppression of oxidative stress and stabilization of calcium homeostasis
-
Yu Z, Luo H, Fu W, Mattson MP (1999) The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis. Exp Neurol 155:302-314.
-
(1999)
Exp Neurol
, vol.155
, pp. 302-314
-
-
Yu, Z.1
Luo, H.2
Fu, W.3
Mattson, M.P.4
-
40
-
-
0141884305
-
Diversity in the mechanisms of neuronal cell death
-
Yuan J, Lipinski M, Degterev A (2003) Diversity in the mechanisms of neuronal cell death. Neuron 40:401-413.
-
(2003)
Neuron
, vol.40
, pp. 401-413
-
-
Yuan, J.1
Lipinski, M.2
Degterev, A.3
-
41
-
-
0025889012
-
Interplay between glutamate and gamma-aminobutyric acid transmitter systems in the physiological regulation of brain-derived neurotrophic factor and nerve growth factor synthesis in hippocampal neurons
-
Zafra F, Castren E, Thoenen H, Lindholm D (1991) Interplay between glutamate and gamma-aminobutyric acid transmitter systems in the physiological regulation of brain-derived neurotrophic factor and nerve growth factor synthesis in hippocampal neurons. Proc Natl Acad Sci USA 88:10037-10041.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 10037-10041
-
-
Zafra, F.1
Castren, E.2
Thoenen, H.3
Lindholm, D.4
|