Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2α

Journal of Cell Biology

Volumn 153, Issue 5, 2001, Pages 1011-1021

  Novoa, Isabel ^a   Zeng, Huiqing ^a   Harding, Heather P ^a   Ron, David ^a,b,c  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Kaplan Cancer Center   (United States)

^c NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Endoplasmic reticulum; Gene expression regulation; Molecular cloning; Signal transduction; Translation

Indexed keywords

GENE PRODUCT; INITIATION FACTOR 2; PHOSPHOPROTEIN PHOSPHATASE 1; PROTEIN GADD34; SERINE; UNCLASSIFIED DRUG;

AMINO ACID DEFICIENCY; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL GROWTH; COMPLEX FORMATION; DNA DAMAGE; ENDOPLASMIC RETICULUM; ENZYME SUBUNIT; GENE ACTIVATION; GENE EXPRESSION REGULATION; MUTATION; NEGATIVE FEEDBACK; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN FOLDING; REPORTER GENE; RETROVIRUS; STRESS; TRANSLATION REGULATION; VIRUS RECOMBINANT;

ACTIVATING TRANSCRIPTION FACTOR 4; ANIMALS; ANTIGENS, DIFFERENTIATION; CARRIER PROTEINS; CATALYTIC DOMAIN; CCAAT-ENHANCER-BINDING PROTEINS; CELL CYCLE PROTEINS; CHO CELLS; CRICETINAE; EIF-2 KINASE; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; FEEDBACK; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; MICE; MODELS, BIOLOGICAL; MOLECULAR CHAPERONES; PEPTIDE INITIATION FACTORS; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PROKARYOTIC INITIATION FACTOR-2; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR CHOP; TRANSCRIPTION FACTORS;

ANIMALIA; EUKARYOTA; UNIDENTIFIED RETROVIRUS;

EID: 0035947778     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.153.5.1011     Document Type: Article

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