Chemical biology investigation of cell death pathways activated by endoplasmic reticulum stress reveals cytoprotective modulators of ASK1

Journal of Biological Chemistry

Volumn 284, Issue 3, 2009, Pages 1593-1603

  Kim, Inki ^a   Shu, Chih Wen ^a   Xu, Wenjie ^a   Shiau, Chung Wai ^a   Grant, Daniel ^a   Vasile, Stefan ^a   Cosford, Nicholas D P ^a   Reed, John C ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE COMPOUNDS; APOPTOSIS; APOPTOTIC; CELL LINES; CELL-BASED; CELL-DEATH PATHWAYS; CHEMICAL BIOLOGIES; CULTURED NEURONS; ENDOPLASMIC RETICULUM STRESS; ENDOPLASMIC RETICULUMS; ER STRESS; HIGH THROUGHPUT SCREENINGS; IN CELLS; KINASE ACTIVITIES; MECHANISM OF ACTIONS; NEURONAL CELLS; P38 MAPK; PROTEIN EXPRESSIONS; PROTEIN KINASE; SIGNALING EVENTS; THAPSIGARGIN; TUMOR NECROSIS FACTORS; TUNICAMYCIN; UNFOLDED PROTEIN RESPONSE; UNFOLDED PROTEINS;

AMINO ACIDS; BIOCHEMISTRY; CELL CULTURE; CELL DEATH; CHEMICAL REACTIONS; CYTOLOGY; DRUG PRODUCTS; NUCLEIC ACIDS; PHOSPHORYLATION; RNA;

CELLS;

APOPTOSIS SIGNAL REGULATING KINASE 1; BENZODIAZEPINE DERIVATIVE; CID 2878822; CID 2879344; CID 2882126; CID 2882794; CID 2891533; CID 2891556; CID 2891579; CID 2891667; CID 2891714; CID 2891837; CID 2891840; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN C JUN; PROTEIN IRE1; SERINE; SMALL INTERFERING RNA; THAPSIGARGIN; TUMOR NECROSIS FACTOR; TUNICAMYCIN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING KINETICS; CELL CULTURE; CELL DEATH; CELL LINE; CELL PROTECTION; CONTROLLED STUDY; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; ENZYME REPRESSION; FEMALE; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; STRUCTURE ACTIVITY RELATION;

14-3-3 PROTEINS; ANIMALS; ANTI-BACTERIAL AGENTS; APOPTOSIS; BENZODIAZEPINONES; ENDOPLASMIC RETICULUM; ENZYME INHIBITORS; HELA CELLS; HUMANS; MAP KINASE KINASE KINASE 5; MICE; NEURONS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN FOLDING; PROTO-ONCOGENE PROTEINS C-JUN; STRESS, PHYSIOLOGICAL; THAPSIGARGIN; TUMOR NECROSIS FACTOR-ALPHA; TUNICAMYCIN;

EID: 59449108481     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M807308200     Document Type: Article

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