Chemical genomics identifies the unfolded protein response as a target for selective cancer cell killing during glucose deprivation

Cancer Research

Volumn 69, Issue 10, 2009, Pages 4225-4234

  Saito, Sakae ^a   Furuno, Aki ^a   Sakurai, Junko ^a   Sakamoto, Asami ^a   Park, Hae Ryong ^c   Shin Ya, Kazuo ^b   Tsuruo, Takashi ^a   Tomida, Akihiro ^a  

^a CANCER CHEMOTHERAPY CENTER   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^c Kyungnam University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ANTINEOPLASTIC AGENT; BUFORMIN; GLUCOSE; METFORMIN; PHENFORMIN; TUNICAMYCIN; UNCLASSIFIED DRUG; VERSIPELOSTATIN; X BOX BINDING PROTEIN 1;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL DESTRUCTION; CELL DEATH; CELLULAR STRESS RESPONSE; CHEMICAL GENOMICS; CONTROLLED STUDY; DRUG MECHANISM; GENE EXPRESSION PROFILING; GENE INDUCTION; GENE REPRESSION; GENOMICS; GLYCOLYSIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SOLID TUMOR; TRANSCRIPTION INITIATION; UNFOLDED PROTEIN RESPONSE;

ACTIVATING TRANSCRIPTION FACTOR 4; CELL DEATH; CELL SURVIVAL; DNA-BINDING PROTEINS; GENE EXPRESSION PROFILING; GENES, REPORTER; GENOMICS; GLUCOSE; HUMANS; HYPOGLYCEMIC AGENTS; MACROLIDES; NEOPLASMS; OLIGOSACCHARIDES; PHENFORMIN; PLASMIDS; PROTEIN DENATURATION; PROTEIN FOLDING; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 66249092010     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-2689     Document Type: Article

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