Targeting endoplasmic reticulum stress in metabolic disease

Expert Opinion on Therapeutic Targets

Volumn 17, Issue 4, 2013, Pages 437-448

  Cao, Stewart Siyan ^a,b   Kaufman, Randal J ^a,b  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

Cell death; Endoplasmic reticulum stress; Metabolic disease; Oxidative stress; Protein folding; Small molecular compounds; Therapeutic targets; Unfolded protein response

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; ANTIOXIDANT; CARBAMAZEPINE; CHAPERONE; INITIATION FACTOR 2ALPHA; PROTEIN IRE1;

APOPTOSIS; ATHEROSCLEROSIS; AUTOPHAGY; CALCIUM HOMEOSTASIS; CELL DEATH; ENDOPLASMIC RETICULUM STRESS; FATTY LIVER; METABOLIC DISORDER; NON INSULIN DEPENDENT DIABETES MELLITUS; NONALCOHOLIC FATTY LIVER; NONHUMAN; OBESITY; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PATHOGENESIS; PROTEIN HOMEOSTASIS; REVIEW; UNFOLDED PROTEIN RESPONSE;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; ENDOPLASMIC RETICULUM STRESS; HUMANS; METABOLIC DISEASES; MOLECULAR TARGETED THERAPY; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE;

EID: 84875143788     PISSN: 14728222     EISSN: 17447631     Source Type: Journal    
DOI: 10.1517/14728222.2013.756471     Document Type: Review

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