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Volumn 107, Issue 35, 2010, Pages 15553-15558

Inositol-requiring enzyme 1α is a key regulator of angiogenesis and invasion in malignant glioma

Author keywords

Mesenchymal drift; Tumor ischemia; Unfolded protein response

Indexed keywords

DECORIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MATRIX PROTEIN; OSTEONECTIN; PROTEIN IRE1; THROMBOSPONDIN 1; VASCULOTROPIN A;

EID: 77957288028     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0914072107     Document Type: Article
Times cited : (248)

References (45)
  • 1
    • 38649112593 scopus 로고    scopus 로고
    • Glioblastoma
    • eds Louis DN, Ohgaki H, Wiestler OD, Cavenee WK (Intl Agency Res Cancer, Lyon, France)
    • Kleihues P, et al. (2007) Glioblastoma. WHO Classification of Tumours of the Central Nervous System, eds Louis DN, Ohgaki H, Wiestler OD, Cavenee WK (Intl Agency Res Cancer, Lyon, France), pp 33-49.
    • (2007) WHO Classification of Tumours of the Central Nervous System , pp. 33-49
    • Kleihues, P.1
  • 2
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet P, Jain RK (2000) Angiogenesis in cancer and other diseases. Nature 407:249-257.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 3
    • 34447632643 scopus 로고    scopus 로고
    • Angiogenesis in brain tumours
    • Jain RK, et al. (2007) Angiogenesis in brain tumours. Nat Rev Neurosci 8:610-622.
    • (2007) Nat Rev Neurosci , vol.8 , pp. 610-622
    • Jain, R.K.1
  • 4
    • 0141670220 scopus 로고    scopus 로고
    • Recurrent haemorrhage from a malignant brain stem glioma: A review of the mechanisms of tumoural haemorrhage
    • Lee G, Zacest AC, Reilly PL (2003) Recurrent haemorrhage from a malignant brain stem glioma: A review of the mechanisms of tumoural haemorrhage. J Clin Neurosci 10:632-634.
    • (2003) J Clin Neurosci , vol.10 , pp. 632-634
    • Lee, G.1    Zacest, A.C.2    Reilly, P.L.3
  • 5
    • 77952309402 scopus 로고    scopus 로고
    • Tumor invasion after treatment of glioblastoma with bevacizumab: Radiographic and pathologic correlation in humans and mice
    • de Groot JF, et al. (2010) Tumor invasion after treatment of glioblastoma with bevacizumab: Radiographic and pathologic correlation in humans and mice. Neurooncol 12:233-242.
    • (2010) Neurooncol , vol.12 , pp. 233-242
    • De Groot, J.F.1
  • 7
    • 60649116477 scopus 로고    scopus 로고
    • Silencing or fueling metastasis with VEGF inhibitors: Antiangiogenesis revisited
    • Loges S, Mazzone M, Hohensinner P, Carmeliet P (2009) Silencing or fueling metastasis with VEGF inhibitors: Antiangiogenesis revisited. Cancer Cell 15:167-170.
    • (2009) Cancer Cell , vol.15 , pp. 167-170
    • Loges, S.1    Mazzone, M.2    Hohensinner, P.3    Carmeliet, P.4
  • 9
    • 39849102836 scopus 로고    scopus 로고
    • HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion
    • Du R, et al. (2008) HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion. Cancer Cell 13:206-220.
    • (2008) Cancer Cell , vol.13 , pp. 206-220
    • Du, R.1
  • 10
    • 60649106195 scopus 로고    scopus 로고
    • Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
    • Pàez-Ribes M, et al. (2009) Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 15:220-231.
    • (2009) Cancer Cell , vol.15 , pp. 220-231
    • Pàez-Ribes, M.1
  • 11
    • 0033822622 scopus 로고    scopus 로고
    • Anti-VEGF antibody treatment of glioblastoma prolongs survival but results in increased vascular cooption
    • Rubenstein JL, et al. (2000) Anti-VEGF antibody treatment of glioblastoma prolongs survival but results in increased vascular cooption. Neoplasia 2:306-314.
    • (2000) Neoplasia , vol.2 , pp. 306-314
    • Rubenstein, J.L.1
  • 12
    • 67650087998 scopus 로고    scopus 로고
    • Combined targeting of interleukin-6 and vascular endothelial growth factor potently inhibits glioma growth and invasiveness
    • Saidi A, et al. (2009) Combined targeting of interleukin-6 and vascular endothelial growth factor potently inhibits glioma growth and invasiveness. Int J Cancer 125:1054-1064.
    • (2009) Int J Cancer , vol.125 , pp. 1054-1064
    • Saidi, A.1
  • 13
    • 27644450912 scopus 로고    scopus 로고
    • Inhibition of glioblastoma angiogenesis and invasion by combined treatments directed against vascular endothelial growth factor receptor-2, epidermal growth factor receptor, and vascular endothelial-cadherin
    • Lamszus K, et al. (2005) Inhibition of glioblastoma angiogenesis and invasion by combined treatments directed against vascular endothelial growth factor receptor-2, epidermal growth factor receptor, and vascular endothelial-cadherin. Clin Cancer Res 11:4934-4940.
    • (2005) Clin Cancer Res , vol.11 , pp. 4934-4940
    • Lamszus, K.1
  • 14
    • 39849084165 scopus 로고    scopus 로고
    • Matrix metalloproteinase-2 regulates vascular patterning and growth affecting tumor cell survival and invasion in GBM
    • Du R, et al. (2008) Matrix metalloproteinase-2 regulates vascular patterning and growth affecting tumor cell survival and invasion in GBM. Neuro-oncol 10:254-264.
    • (2008) Neuro-oncol , vol.10 , pp. 254-264
    • Du, R.1
  • 15
    • 33750814849 scopus 로고    scopus 로고
    • Angiogenesis-independent tumor growth mediated by stem-like cancer cells
    • Sakariassen PO, et al. (2006) Angiogenesis-independent tumor growth mediated by stem-like cancer cells. Proc Natl Acad Sci USA 103:16466-16471.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 16466-16471
    • Sakariassen, P.O.1
  • 16
    • 41349091447 scopus 로고    scopus 로고
    • Glioma cells on the run - The migratory transcriptome of 10 human glioma cell lines
    • Demuth T, et al. (2008) Glioma cells on the run - the migratory transcriptome of 10 human glioma cell lines. BMC Genomics 9:54.
    • (2008) BMC Genomics , vol.9 , pp. 54
    • Demuth, T.1
  • 17
    • 59149083473 scopus 로고    scopus 로고
    • Transcriptional switch of dormant tumors to fast-growing angiogenic phenotype
    • Almog N, et al. (2009) Transcriptional switch of dormant tumors to fast-growing angiogenic phenotype. Cancer Res 69:836-844.
    • (2009) Cancer Res , vol.69 , pp. 836-844
    • Almog, N.1
  • 18
    • 0142157702 scopus 로고    scopus 로고
    • Classification of human astrocytic gliomas on the basis of gene expression: A correlated group of genes with angiogenic activity emerges as a strong predictor of subtypes
    • Godard S, et al. (2003) Classification of human astrocytic gliomas on the basis of gene expression: A correlated group of genes with angiogenic activity emerges as a strong predictor of subtypes. Cancer Res 63:6613-6625.
    • (2003) Cancer Res , vol.63 , pp. 6613-6625
    • Godard, S.1
  • 19
    • 0038049137 scopus 로고    scopus 로고
    • Tumour-cell invasion and migration: Diversity and escape mechanisms
    • DOI 10.1038/nrc1075
    • Friedl P, Wolf K (2003) Tumour-cell invasion and migration: Diversity and escape mechanisms. Nat Rev Cancer 3:362-374. (Pubitemid 37328856)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.5 , pp. 362-374
    • Friedl, P.1    Wolf, K.2
  • 20
    • 34250899722 scopus 로고    scopus 로고
    • Signal integration in the endoplasmic reticulum unfolded protein response
    • Ron D, Walter P (2007) Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 8:519-529.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 519-529
    • Ron, D.1    Walter, P.2
  • 21
    • 10444226462 scopus 로고    scopus 로고
    • ER stress and the unfolded protein response
    • Schröder M, Kaufman RJ (2005) ER stress and the unfolded protein response. Mutat Res 569:29-63.
    • (2005) Mutat Res , vol.569 , pp. 29-63
    • Schröder, M.1    Kaufman, R.J.2
  • 22
    • 68549092781 scopus 로고    scopus 로고
    • Regulated Ire1-dependent decay of messenger RNAs in mammalian cells
    • Hollien J, et al. (2009) Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. J Cell Biol 186:323-331.
    • (2009) J Cell Biol , vol.186 , pp. 323-331
    • Hollien, J.1
  • 23
    • 33947101019 scopus 로고    scopus 로고
    • Patterns of somatic mutation in human cancer genomes
    • Greenman C, et al. (2007) Patterns of somatic mutation in human cancer genomes. Nature 446:153-158.
    • (2007) Nature , vol.446 , pp. 153-158
    • Greenman, C.1
  • 24
    • 34547114745 scopus 로고    scopus 로고
    • IRE1 signaling is essential for ischemia-induced vascular endothelial growth factor-A expression and contributes to angiogenesis and tumor growth in vivo
    • Drogat B, et al. (2007) IRE1 signaling is essential for ischemia-induced vascular endothelial growth factor-A expression and contributes to angiogenesis and tumor growth in vivo. Cancer Res 67:6700-6707.
    • (2007) Cancer Res , vol.67 , pp. 6700-6707
    • Drogat, B.1
  • 25
    • 69049083657 scopus 로고    scopus 로고
    • Imaging glioma cell invasion in vivo reveals mechanisms of dissemination and peritumoral angiogenesis
    • Winkler F, et al. (2009) Imaging glioma cell invasion in vivo reveals mechanisms of dissemination and peritumoral angiogenesis. Glia 57:1306-1315.
    • (2009) Glia , vol.57 , pp. 1306-1315
    • Winkler, F.1
  • 27
    • 0028870050 scopus 로고
    • Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: Implications for tumor angiogenesis
    • Shweiki D, Neeman M, Itin A, Keshet E (1995) Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: Implications for tumor angiogenesis. Proc Natl Acad Sci USA 92:768-772.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 768-772
    • Shweiki, D.1    Neeman, M.2    Itin, A.3    Keshet, E.4
  • 28
    • 10344222124 scopus 로고    scopus 로고
    • The role of the unfolded protein response in tumour development: Friend or foe?
    • Ma Y, Hendershot LM (2004) The role of the unfolded protein response in tumour development: Friend or foe? Nat Rev Cancer 4:966-977.
    • (2004) Nat Rev Cancer , vol.4 , pp. 966-977
    • Ma, Y.1    Hendershot, L.M.2
  • 29
    • 0038037735 scopus 로고    scopus 로고
    • Regulation of angiogenesis by hypoxia: Role of the HIF system
    • Pugh CW, Ratcliffe PJ (2003) Regulation of angiogenesis by hypoxia: Role of the HIF system. Nat Med 9:677-684.
    • (2003) Nat Med , vol.9 , pp. 677-684
    • Pugh, C.W.1    Ratcliffe, P.J.2
  • 30
    • 34250794495 scopus 로고    scopus 로고
    • XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks
    • Acosta-Alvear D, et al. (2007) XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks. Mol Cell 27:53-66.
    • (2007) Mol Cell , vol.27 , pp. 53-66
    • Acosta-Alvear, D.1
  • 31
    • 0038675136 scopus 로고    scopus 로고
    • The X-box binding protein-1 transcription factor is required for plasma cell differentiation and the unfolded protein response
    • DOI 10.1034/j.1600-065X.2003.00057.x
    • Iwakoshi NN, Lee AH, Glimcher LH (2003) The X-box binding protein-1 transcription factor is required for plasma cell differentiation and the unfolded protein response. Immunol Rev 194:29-38. (Pubitemid 36886426)
    • (2003) Immunological Reviews , vol.194 , pp. 29-38
    • Iwakoshi, N.N.1    Lee, A.-H.2    Glimcher, L.H.3
  • 32
  • 33
    • 29244454269 scopus 로고    scopus 로고
    • Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis
    • Nawrocki ST, et al. (2005) Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis. Cancer Res 65:11658-11666.
    • (2005) Cancer Res , vol.65 , pp. 11658-11666
    • Nawrocki, S.T.1
  • 34
    • 34547197343 scopus 로고    scopus 로고
    • The kinase inhibitor sorafenib induces cell death through a process involving inductionof endoplasmic reticulumstress
    • Rahmani M, et al. (2007) The kinase inhibitor sorafenib induces cell death through a process involving inductionof endoplasmic reticulumstress. Mol Cell Biol 27:5499-5513.
    • (2007) Mol Cell Biol , vol.27 , pp. 5499-5513
    • Rahmani, M.1
  • 35
    • 0029787294 scopus 로고    scopus 로고
    • Dichotomy of astrocytoma migration and proliferation
    • Giese A, et al. (1996) Dichotomy of astrocytoma migration and proliferation. Int J Cancer 67:275-282.
    • (1996) Int J Cancer , vol.67 , pp. 275-282
    • Giese, A.1
  • 37
    • 33749366427 scopus 로고    scopus 로고
    • Primary glioblastomas express mesenchymal stem-like properties
    • Tso CL, et al. (2006) Primary glioblastomas express mesenchymal stem-like properties. Mol Cancer Res 4:607-619.
    • (2006) Mol Cancer Res , vol.4 , pp. 607-619
    • Tso, C.L.1
  • 38
    • 33747849846 scopus 로고    scopus 로고
    • Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1
    • Lipson KL, et al. (2006) Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1. Cell Metab 4:245-254.
    • (2006) Cell Metab , vol.4 , pp. 245-254
    • Lipson, K.L.1
  • 39
    • 0034643336 scopus 로고    scopus 로고
    • Rapid degradation of a large fraction of newly synthesized proteins by proteasomes
    • Schubert U, et al. (2000) Rapid degradation of a large fraction of newly synthesized proteins by proteasomes. Nature 404:770-774.
    • (2000) Nature , vol.404 , pp. 770-774
    • Schubert, U.1
  • 40
    • 34250676556 scopus 로고    scopus 로고
    • Nonrandom variations in human cancer ESTs indicate that mRNA heterogeneity increases during carcinogenesis
    • Brulliard M, et al. (2007) Nonrandom variations in human cancer ESTs indicate that mRNA heterogeneity increases during carcinogenesis. Proc Natl Acad Sci USA 104:7522-7527.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 7522-7527
    • Brulliard, M.1
  • 41
    • 33746886623 scopus 로고    scopus 로고
    • "Translating" tumor hypoxia: Unfolded protein response (UPR)-dependent and UPR-independent pathways
    • Koumenis C, Wouters BG (2006) "Translating" tumor hypoxia: Unfolded protein response (UPR)-dependent and UPR-independent pathways. Mol Cancer Res 4:423-436.
    • (2006) Mol Cancer Res , vol.4 , pp. 423-436
    • Koumenis, C.1    Wouters, B.G.2
  • 42
    • 59149092493 scopus 로고    scopus 로고
    • The role of tumor cell-derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth
    • Bennewith KL, et al. (2009) The role of tumor cell-derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth. Cancer Res 69:775-784.
    • (2009) Cancer Res , vol.69 , pp. 775-784
    • Bennewith, K.L.1
  • 43
    • 60549117718 scopus 로고    scopus 로고
    • Effects of sunitinib on tumor hemodynamics and delivery of chemotherapy
    • Czabanka M, Vinci M, Heppner F, Ullrich A, Vajkoczy P (2009) Effects of sunitinib on tumor hemodynamics and delivery of chemotherapy. Int J Cancer 124:1293-1300.
    • (2009) Int J Cancer , vol.124 , pp. 1293-1300
    • Czabanka, M.1    Vinci, M.2    Heppner, F.3    Ullrich, A.4    Vajkoczy, P.5
  • 44
    • 0031924299 scopus 로고    scopus 로고
    • Characterization of angiogenesis and microcirculation of high-grade glioma: An intravital multifluorescence microscopic approach in the athymic nude mouse
    • Vajkoczy P, Schilling L, Ullrich A, Schmiedek P, Menger MD (1998) Characterization of angiogenesis and microcirculation of high-grade glioma: An intravitalmultifluorescence microscopic approach inthe athymicnudemouse. J Cereb Blood Flow Metab 18:510-520. (Pubitemid 28213535)
    • (1998) Journal of Cerebral Blood Flow and Metabolism , vol.18 , Issue.5 , pp. 510-520
    • Vajkoczy, P.1    Schilling, L.2    Ullrich, A.3    Schmiedek, P.4    Menger, M.D.5
  • 45
    • 28744458859 scopus 로고    scopus 로고
    • Bioconductor: Open software development for computational biology and bioinformatics
    • Gentleman RC, et al. (2004) Bioconductor: Open software development for computational biology and bioinformatics. Genome Biol 5:R80.
    • (2004) Genome Biol , vol.5
    • Gentleman, R.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.