The protective effect of dantrolene on ischemic neuronal cell death is associated with reduced expression of endoplasmic reticulum stress markers

Brain Research

Volumn 1048, Issue 1-2, 2005, Pages 59-68

  Li, Feng ^a   Hayashi, Takeshi ^a   Jin, Guang ^a   Deguchi, Kentaro ^a   Nagotani, Shoko ^a   Nagano, Isao ^a   Shoji, Mikio ^a   Chan, Pak H ^b   Abe, Koji ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Dantrolene; Endoplasmic reticulum; Ischemia; Rat

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; DANTROLENE; DOUBLE STRANDED RNA; INITIATION FACTOR 2ALPHA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN MITOCHONDRION; BRAIN PERFUSION; BRAIN PROTECTION; CONTROLLED STUDY; DRUG INHIBITION; ENDOPLASMIC RETICULUM; IMMUNOREACTIVITY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL NECROSIS; NEUROPROTECTION; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; RNA STRUCTURE; SIGNAL TRANSDUCTION;

ACTIVATING TRANSCRIPTION FACTOR 4; ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; CCAAT-ENHANCER-BINDING PROTEINS; CELL COUNT; CELL DEATH; DANTROLENE; DISEASE MODELS, ANIMAL; EIF-2 KINASE; ENDOPLASMIC RETICULUM; EUKARYOTIC INITIATION FACTOR-2; GENE EXPRESSION REGULATION; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INFARCTION, MIDDLE CEREBRAL ARTERY; ISCHEMIA; MALE; MUSCLE RELAXANTS, CENTRAL; NEURONS; PHOSPHOPYRUVATE HYDRATASE; PHOSPHORYLATION; RATS; RATS, WISTAR; REPERFUSION; TIME FACTORS; TRANSCRIPTION FACTOR CHOP; TRANSCRIPTION FACTORS;

EID: 20444390622     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2005.04.058     Document Type: Article

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