Perk-dependent translational regulation promotes tumor cell adaptation and angiogenesis in response to hypoxic stress

Molecular and Cellular Biology

Volumn 26, Issue 24, 2006, Pages 9517-9532

  Blais, Jaime D ^a,b   Addison, Christina L ^a   Edge, Robert ^a,b   Falls, Theresa ^a   Zhao, Huijun ^a   Wary, Kishore ^d   Koumenis, Costas ^e   Harding, Heather P ^f   Ron, David ^f   Holcik, Martin ^c   Bell, John C ^a  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

^d UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

^f NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENIC FACTOR; CELL ADHESION MOLECULE; CELL ENZYME; COLLAGEN TYPE 1; K RAS PROTEIN; PROTEIN KINASE; PROTEIN PERK; PROTEIN VCIP; RIBOSOME RNA;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME REGULATION; GENE IDENTIFICATION; GENE INDUCTION; HUMAN; HUMAN CELL; HYPOXIA; INTEGRATED STRESS RESPONSE; MICROARRAY ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROCESSING; REGULATORY MECHANISM; RNA ANALYSIS; RNA TRANSLATION; SIGNAL TRANSDUCTION; STRESS; TRANSLATION REGULATION; TUMOR CELL CULTURE; TUMOR VASCULARIZATION;

ANIMALS; ANOXIA; CELL LINE, TRANSFORMED; EIF-2 KINASE; FIBROBLASTS; GENE EXPRESSION PROFILING; HT29 CELLS; HUMANS; MICE; MICE, NUDE; NEOPLASMS, EXPERIMENTAL; NEOVASCULARIZATION, PATHOLOGIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN BIOSYNTHESIS; STRESS;

EID: 33845465578     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.01145-06     Document Type: Article

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