-
1
-
-
0031961688
-
Regulation of translational initiation during cellular responses to stress
-
Brostrom C.O., Brostrom M.A. Regulation of translational initiation during cellular responses to stress. Prog. Nucleic Acid Res. Mol. Biol. 1998, 58:79-125.
-
(1998)
Prog. Nucleic Acid Res. Mol. Biol.
, vol.58
, pp. 79-125
-
-
Brostrom, C.O.1
Brostrom, M.A.2
-
2
-
-
34047136169
-
The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis
-
Carrasco D.R., Sukhdeo K., Protopopova M., Sinha R., Enos M., Carrasco D.E., Zheng M., Mani M., Henderson J., Pinkus G.S., et al. The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis. Cancer Cell 2007, 11:349-360.
-
(2007)
Cancer Cell
, vol.11
, pp. 349-360
-
-
Carrasco, D.R.1
Sukhdeo, K.2
Protopopova, M.3
Sinha, R.4
Enos, M.5
Carrasco, D.E.6
Zheng, M.7
Mani, M.8
Henderson, J.9
Pinkus, G.S.10
-
3
-
-
84869087503
-
MiR-211 is a prosurvival microRNA that regulates chop expression in a PERK-dependent manner
-
Chitnis N.S., Pytel D., Bobrovnikova-Marjon E., Pant D., Zheng H., Maas N.L., Frederick B., Kushner J.A., Chodosh L.A., Koumenis C., et al. miR-211 is a prosurvival microRNA that regulates chop expression in a PERK-dependent manner. Mol. Cell 2012, 48:353-364.
-
(2012)
Mol. Cell
, vol.48
, pp. 353-364
-
-
Chitnis, N.S.1
Pytel, D.2
Bobrovnikova-Marjon, E.3
Pant, D.4
Zheng, H.5
Maas, N.L.6
Frederick, B.7
Kushner, J.A.8
Chodosh, L.A.9
Koumenis, C.10
-
4
-
-
75149148563
-
Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer
-
DeBerardinis R.J., Cheng T. Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer. Oncogene 2010, 29:313-324.
-
(2010)
Oncogene
, vol.29
, pp. 313-324
-
-
DeBerardinis, R.J.1
Cheng, T.2
-
5
-
-
33749184798
-
Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway
-
Denoyelle C., Abou-Rjaily G., Bezrookove V., Verhaegen M., Johnson T.M., Fullen D.R., Pointer J.N., Gruber S.B., Su L.D., Nikiforov M.A., et al. Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway. Nat. Cell Biol. 2006, 8:1053-1063.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 1053-1063
-
-
Denoyelle, C.1
Abou-Rjaily, G.2
Bezrookove, V.3
Verhaegen, M.4
Johnson, T.M.5
Fullen, D.R.6
Pointer, J.N.7
Gruber, S.B.8
Su, L.D.9
Nikiforov, M.A.10
-
6
-
-
78650885452
-
The ER UDPase ENTPD5 promotes protein N-glycosylation, the Warburg effect, and proliferation in the PTEN pathway
-
Fang M., Shen Z., Huang S., Zhao L., Chen S., Mak T.W., Wang X. The ER UDPase ENTPD5 promotes protein N-glycosylation, the Warburg effect, and proliferation in the PTEN pathway. Cell 2010, 143:711-724.
-
(2010)
Cell
, vol.143
, pp. 711-724
-
-
Fang, M.1
Shen, Z.2
Huang, S.3
Zhao, L.4
Chen, S.5
Mak, T.W.6
Wang, X.7
-
7
-
-
27744573105
-
Inducible dimerization of RET reveals a specific AKT deregulation in oncogenic signaling
-
Frêche B., Guillaumot P., Charmetant J., Pelletier L., Luquain C., Christiansen D., Billaud M., Manié S.N. Inducible dimerization of RET reveals a specific AKT deregulation in oncogenic signaling. J. Biol. Chem. 2005, 280:36584-36591.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 36584-36591
-
-
Frêche, B.1
Guillaumot, P.2
Charmetant, J.3
Pelletier, L.4
Luquain, C.5
Christiansen, D.6
Billaud, M.7
Manié, S.N.8
-
8
-
-
46749121459
-
Causes and consequences of increased glucose metabolism of cancers
-
Gillies R.J., Robey I., Gatenby R.A. Causes and consequences of increased glucose metabolism of cancers. J. Nucl. Med. 2008, 49(Suppl 2):24S-42S.
-
(2008)
J. Nucl. Med.
, vol.49
, Issue.SUPPL 2
-
-
Gillies, R.J.1
Robey, I.2
Gatenby, R.A.3
-
9
-
-
0033590451
-
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
-
Harding H.P., Zhang Y., Ron D. Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature 1999, 397:271-274.
-
(1999)
Nature
, vol.397
, pp. 271-274
-
-
Harding, H.P.1
Zhang, Y.2
Ron, D.3
-
10
-
-
0037353039
-
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
-
Harding H.P., Zhang Y., Zeng H., Novoa I., Lu P.D., Calfon M., Sadri N., Yun C., Popko B., Paules R., et al. An integrated stress response regulates amino acid metabolism and resistance to oxidative stress. Mol. Cell 2003, 11:619-633.
-
(2003)
Mol. Cell
, vol.11
, pp. 619-633
-
-
Harding, H.P.1
Zhang, Y.2
Zeng, H.3
Novoa, I.4
Lu, P.D.5
Calfon, M.6
Sadri, N.7
Yun, C.8
Popko, B.9
Paules, R.10
-
11
-
-
84870546460
-
ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth
-
Hart L.S., Cunningham J.T., Datta T., Dey S., Tameire F., Lehman S.L., Qiu B., Zhang H., Cerniglia G., Bi M., et al. ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth. J. Clin. Invest. 2012, 122:4621-4634.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 4621-4634
-
-
Hart, L.S.1
Cunningham, J.T.2
Datta, T.3
Dey, S.4
Tameire, F.5
Lehman, S.L.6
Qiu, B.7
Zhang, H.8
Cerniglia, G.9
Bi, M.10
-
12
-
-
0028198111
-
How N-linked oligosaccharides affect glycoprotein folding in the endoplasmic reticulum
-
Helenius A. How N-linked oligosaccharides affect glycoprotein folding in the endoplasmic reticulum. Mol. Biol. Cell 1994, 5:253-265.
-
(1994)
Mol. Biol. Cell
, vol.5
, pp. 253-265
-
-
Helenius, A.1
-
13
-
-
0035953550
-
Somatic activation of the K-ras oncogene causes early onset lung cancer in mice
-
Johnson L., Mercer K., Greenbaum D., Bronson R.T., Crowley D., Tuveson D.A., Jacks T. Somatic activation of the K-ras oncogene causes early onset lung cancer in mice. Nature 2001, 410:1111-1116.
-
(2001)
Nature
, vol.410
, pp. 1111-1116
-
-
Johnson, L.1
Mercer, K.2
Greenbaum, D.3
Bronson, R.T.4
Crowley, D.5
Tuveson, D.A.6
Jacks, T.7
-
14
-
-
61849135453
-
Tumor suppressors and cell metabolism: a recipe for cancer growth
-
Jones R.G., Thompson C.B. Tumor suppressors and cell metabolism: a recipe for cancer growth. Genes Dev. 2009, 23:537-548.
-
(2009)
Genes Dev.
, vol.23
, pp. 537-548
-
-
Jones, R.G.1
Thompson, C.B.2
-
15
-
-
0036086064
-
The unfolded protein response in nutrient sensing and differentiation
-
Kaufman R.J., Scheuner D., Schröder M., Shen X., Lee K., Liu C.Y., Arnold S.M. The unfolded protein response in nutrient sensing and differentiation. Nat. Rev. Mol. Cell Biol. 2002, 3:411-421.
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 411-421
-
-
Kaufman, R.J.1
Scheuner, D.2
Schröder, M.3
Shen, X.4
Lee, K.5
Liu, C.Y.6
Arnold, S.M.7
-
16
-
-
84862518603
-
Expression of ER stress and autophagy-related molecules in human non-small cell lung cancer and premalignant lesions
-
Kim K.M., Yu T.K., Chu H.H., Park H.S., Jang K.Y., Moon W.S., Kang M.J., Lee D.G., Kim M.H., Lee J.H., Chung M.J. Expression of ER stress and autophagy-related molecules in human non-small cell lung cancer and premalignant lesions. Int. J. Cancer 2012, 131:E362-E370.
-
(2012)
Int. J. Cancer
, vol.131
-
-
Kim, K.M.1
Yu, T.K.2
Chu, H.H.3
Park, H.S.4
Jang, K.Y.5
Moon, W.S.6
Kang, M.J.7
Lee, D.G.8
Kim, M.H.9
Lee, J.H.10
Chung, M.J.11
-
17
-
-
34250205154
-
Phosphorylation of eIF2alpha is required for mRNA translation inhibition and survival during moderate hypoxia
-
Koritzinsky M., Rouschop K.M., van den Beucken T., Magagnin M.G., Savelkouls K., Lambin P., Wouters B.G. Phosphorylation of eIF2alpha is required for mRNA translation inhibition and survival during moderate hypoxia. Radiother. Oncol. 2007, 83:353-361.
-
(2007)
Radiother. Oncol.
, vol.83
, pp. 353-361
-
-
Koritzinsky, M.1
Rouschop, K.M.2
van den Beucken, T.3
Magagnin, M.G.4
Savelkouls, K.5
Lambin, P.6
Wouters, B.G.7
-
18
-
-
0142059951
-
XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response
-
Lee A.H., Iwakoshi N.N., Glimcher L.H. XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response. Mol. Cell. Biol. 2003, 23:7448-7459.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 7448-7459
-
-
Lee, A.H.1
Iwakoshi, N.N.2
Glimcher, L.H.3
-
19
-
-
58449084895
-
Divergent effects of PERK and IRE1 signaling on cell viability
-
Lin J.H., Li H., Zhang Y., Ron D., Walter P. Divergent effects of PERK and IRE1 signaling on cell viability. PLoS ONE 2009, 4:e4170.
-
(2009)
PLoS ONE
, vol.4
-
-
Lin, J.H.1
Li, H.2
Zhang, Y.3
Ron, D.4
Walter, P.5
-
20
-
-
57649221592
-
Hypoxic reactive oxygen species regulate the integrated stress response and cell survival
-
Liu L., Wise D.R., Diehl J.A., Simon M.C. Hypoxic reactive oxygen species regulate the integrated stress response and cell survival. J. Biol. Chem. 2008, 283:31153-31162.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 31153-31162
-
-
Liu, L.1
Wise, D.R.2
Diehl, J.A.3
Simon, M.C.4
-
21
-
-
10344222124
-
The role of the unfolded protein response in tumour development: friend or foe?
-
Ma Y., Hendershot L.M. The role of the unfolded protein response in tumour development: friend or foe?. Nat. Rev. Cancer 2004, 4:966-977.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 966-977
-
-
Ma, Y.1
Hendershot, L.M.2
-
22
-
-
78649364332
-
Hypoxia-inducible factors and the response to hypoxic stress
-
Majmundar A.J., Wong W.J., Simon M.C. Hypoxia-inducible factors and the response to hypoxic stress. Mol. Cell 2010, 40:294-309.
-
(2010)
Mol. Cell
, vol.40
, pp. 294-309
-
-
Majmundar, A.J.1
Wong, W.J.2
Simon, M.C.3
-
23
-
-
79551634458
-
Autophagy in tumorigenesis and energy metabolism: friend by day, foe by night
-
Mathew R., White E. Autophagy in tumorigenesis and energy metabolism: friend by day, foe by night. Curr. Opin. Genet. Dev. 2011, 21:113-119.
-
(2011)
Curr. Opin. Genet. Dev.
, vol.21
, pp. 113-119
-
-
Mathew, R.1
White, E.2
-
24
-
-
77956706423
-
Phosphorylation of eIF2α at serine 51 is an important determinant of cell survival and adaptation to glucose deficiency
-
Muaddi H., Majumder M., Peidis P., Papadakis A.I., Holcik M., Scheuner D., Kaufman R.J., Hatzoglou M., Koromilas A.E. Phosphorylation of eIF2α at serine 51 is an important determinant of cell survival and adaptation to glucose deficiency. Mol. Biol. Cell 2010, 21:3220-3231.
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 3220-3231
-
-
Muaddi, H.1
Majumder, M.2
Peidis, P.3
Papadakis, A.I.4
Holcik, M.5
Scheuner, D.6
Kaufman, R.J.7
Hatzoglou, M.8
Koromilas, A.E.9
-
25
-
-
0023616782
-
Glucose utilization in vivo by human pulmonary neoplasms
-
Nolop K.B., Rhodes C.G., Brudin L.H., Beaney R.P., Krausz T., Jones T., Hughes J.M. Glucose utilization in vivo by human pulmonary neoplasms. Cancer 1987, 60:2682-2689.
-
(1987)
Cancer
, vol.60
, pp. 2682-2689
-
-
Nolop, K.B.1
Rhodes, C.G.2
Brudin, L.H.3
Beaney, R.P.4
Krausz, T.5
Jones, T.6
Hughes, J.M.7
-
26
-
-
44849124523
-
Dual function of pancreatic endoplasmic reticulum kinase in tumor cell growth arrest and survival
-
Ranganathan A.C., Ojha S., Kourtidis A., Conklin D.S., Aguirre-Ghiso J.A. Dual function of pancreatic endoplasmic reticulum kinase in tumor cell growth arrest and survival. Cancer Res. 2008, 68:3260-3268.
-
(2008)
Cancer Res.
, vol.68
, pp. 3260-3268
-
-
Ranganathan, A.C.1
Ojha, S.2
Kourtidis, A.3
Conklin, D.S.4
Aguirre-Ghiso, J.A.5
-
27
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
Ron D., Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat. Rev. Mol. Cell Biol. 2007, 8:519-529.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
28
-
-
35348827324
-
That which does not kill me makes me stronger: adapting to chronic ER stress
-
Rutkowski D.T., Kaufman R.J. That which does not kill me makes me stronger: adapting to chronic ER stress. Trends Biochem. Sci. 2007, 32:469-476.
-
(2007)
Trends Biochem. Sci.
, vol.32
, pp. 469-476
-
-
Rutkowski, D.T.1
Kaufman, R.J.2
-
29
-
-
34548512233
-
The role of p58IPK in protecting the stressed endoplasmic reticulum
-
Rutkowski D.T., Kang S.W., Goodman A.G., Garrison J.L., Taunton J., Katze M.G., Kaufman R.J., Hegde R.S. The role of p58IPK in protecting the stressed endoplasmic reticulum. Mol. Biol. Cell 2007, 18:3681-3691.
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 3681-3691
-
-
Rutkowski, D.T.1
Kang, S.W.2
Goodman, A.G.3
Garrison, J.L.4
Taunton, J.5
Katze, M.G.6
Kaufman, R.J.7
Hegde, R.S.8
-
30
-
-
39749136524
-
Inhibition of proliferation by PERK regulates mammary acinar morphogenesis and tumor formation
-
Sequeira S.J., Ranganathan A.C., Adam A.P., Iglesias B.V., Farias E.F., Aguirre-Ghiso J.A. Inhibition of proliferation by PERK regulates mammary acinar morphogenesis and tumor formation. PLoS ONE 2007, 2:e615.
-
(2007)
PLoS ONE
, vol.2
-
-
Sequeira, S.J.1
Ranganathan, A.C.2
Adam, A.P.3
Iglesias, B.V.4
Farias, E.F.5
Aguirre-Ghiso, J.A.6
-
31
-
-
0032539534
-
A unique glucose-dependent apoptotic pathway induced by c-Myc
-
Shim H., Chun Y.S., Lewis B.C., Dang C.V. A unique glucose-dependent apoptotic pathway induced by c-Myc. Proc. Natl. Acad. Sci. USA 1998, 95:1511-1516.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 1511-1516
-
-
Shim, H.1
Chun, Y.S.2
Lewis, B.C.3
Dang, C.V.4
-
32
-
-
75149165640
-
Imaging the unfolded protein response in primary tumors reveals microenvironments with metabolic variations that predict tumor growth
-
Spiotto M.T., Banh A., Papandreou I., Cao H., Galvez M.G., Gurtner G.C., Denko N.C., Le Q.T., Koong A.C. Imaging the unfolded protein response in primary tumors reveals microenvironments with metabolic variations that predict tumor growth. Cancer Res. 2010, 70:78-88.
-
(2010)
Cancer Res.
, vol.70
, pp. 78-88
-
-
Spiotto, M.T.1
Banh, A.2
Papandreou, I.3
Cao, H.4
Galvez, M.G.5
Gurtner, G.C.6
Denko, N.C.7
Le, Q.T.8
Koong, A.C.9
-
33
-
-
79952264011
-
Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress
-
Tabas I., Ron D. Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress. Nat. Cell Biol. 2011, 13:184-190.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 184-190
-
-
Tabas, I.1
Ron, D.2
-
34
-
-
66249108601
-
Understanding the Warburg effect: the metabolic requirements of cell proliferation
-
Vander Heiden M.G., Cantley L.C., Thompson C.B. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 2009, 324:1029-1033.
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
35
-
-
84858604270
-
Metabolic reprogramming: a cancer hallmark even warburg did not anticipate
-
Ward P.S., Thompson C.B. Metabolic reprogramming: a cancer hallmark even warburg did not anticipate. Cancer Cell 2012, 21:297-308.
-
(2012)
Cancer Cell
, vol.21
, pp. 297-308
-
-
Ward, P.S.1
Thompson, C.B.2
-
36
-
-
78650181190
-
The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism
-
Wellen K.E., Lu C., Mancuso A., Lemons J.M., Ryczko M., Dennis J.W., Rabinowitz J.D., Coller H.A., Thompson C.B. The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism. Genes Dev. 2010, 24:2784-2799.
-
(2010)
Genes Dev.
, vol.24
, pp. 2784-2799
-
-
Wellen, K.E.1
Lu, C.2
Mancuso, A.3
Lemons, J.M.4
Ryczko, M.5
Dennis, J.W.6
Rabinowitz, J.D.7
Coller, H.A.8
Thompson, C.B.9
-
37
-
-
0037058574
-
Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK
-
Yan W., Frank C.L., Korth M.J., Sopher B.L., Novoa I., Ron D., Katze M.G. Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK. Proc. Natl. Acad. Sci. USA 2002, 99:15920-15925.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 15920-15925
-
-
Yan, W.1
Frank, C.L.2
Korth, M.J.3
Sopher, B.L.4
Novoa, I.5
Ron, D.6
Katze, M.G.7
-
38
-
-
77953565102
-
The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation
-
Ye J., Kumanova M., Hart L.S., Sloane K., Zhang H., De Panis D.N., Bobrovnikova-Marjon E., Diehl J.A., Ron D., Koumenis C. The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation. EMBO J. 2010, 29:2082-2096.
-
(2010)
EMBO J.
, vol.29
, pp. 2082-2096
-
-
Ye, J.1
Kumanova, M.2
Hart, L.S.3
Sloane, K.4
Zhang, H.5
De Panis, D.N.6
Bobrovnikova-Marjon, E.7
Diehl, J.A.8
Ron, D.9
Koumenis, C.10
-
39
-
-
70349331678
-
Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells
-
Yun J., Rago C., Cheong I., Pagliarini R., Angenendt P., Rajagopalan H., Schmidt K., Willson J.K., Markowitz S., Zhou S., et al. Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells. Science 2009, 325:1555-1559.
-
(2009)
Science
, vol.325
, pp. 1555-1559
-
-
Yun, J.1
Rago, C.2
Cheong, I.3
Pagliarini, R.4
Angenendt, P.5
Rajagopalan, H.6
Schmidt, K.7
Willson, J.K.8
Markowitz, S.9
Zhou, S.10
-
40
-
-
0032054744
-
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum
-
Zinszner H., Kuroda M., Wang X., Batchvarova N., Lightfoot R.T., Remotti H., Stevens J.L., Ron D. CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev. 1998, 12:982-995.
-
(1998)
Genes Dev.
, vol.12
, pp. 982-995
-
-
Zinszner, H.1
Kuroda, M.2
Wang, X.3
Batchvarova, N.4
Lightfoot, R.T.5
Remotti, H.6
Stevens, J.L.7
Ron, D.8
|