Activation of the unfolded protein response enhances motor recovery after spinal cord injury

Cell Death and Disease

Volumn 3, Issue 2, 2012, Pages

  Valenzuela, V ^a,b,c   Collyer, E ^b   Armentano, D ^d   Parsons, G B ^d   Court, F A ^b,e   Hetz, C ^a,c,e,f  

^a UNIVERSITY OF CHILE   (Chile)

^b PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^c UNIVERSITY OF CHILE   (Chile)

^d GENZYME CORPORATION   (United States)

^e Neurounion Biomedical Foundation   (Chile)

^f HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Endoplasmic reticulum stress; Motor dysfunction; Spinal cord injury; Unfolded protein response; XBP1

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; INTERLEUKIN 1BETA; INTERLEUKIN 6; PARVOVIRUS VECTOR; TUMOR NECROSIS FACTOR ALPHA; X BOX BINDING PROTEIN 1; ATF4 PROTEIN, MOUSE; DNA BINDING PROTEIN; REGULATORY FACTOR X TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOPLASMIC RETICULUM STRESS; INFLAMMATION; LOCOMOTION; MICROGLIA; MOUSE; NERVE CELL LESION; NERVE FIBER; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPINAL CORD HEMISECTION; SPINAL CORD INJURY; UNFOLDED PROTEIN RESPONSE; UPREGULATION; ADENO ASSOCIATED VIRUS; ANIMAL; C57BL MOUSE; CELL COUNT; ENDOPLASMIC RETICULUM; GENE VECTOR; GENETICS; INTRASPINAL DRUG ADMINISTRATION; METABOLISM; MOUSE MUTANT; PATHOLOGY; SIGNAL TRANSDUCTION; SPINAL CORD; TRANSCRIPTION INITIATION;

ADENO-ASSOCIATED VIRUS; MUS;

ACTIVATING TRANSCRIPTION FACTOR 4; ANIMALS; AXONS; CELL COUNT; DEPENDOVIRUS; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM; GENETIC VECTORS; INJECTIONS, SPINAL; LOCOMOTION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OLIGODENDROGLIA; SIGNAL TRANSDUCTION; SPINAL CORD; SPINAL CORD INJURIES; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION; UNFOLDED PROTEIN RESPONSE;

EID: 84857852395     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2012.8     Document Type: Article

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