XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease

Cell

Volumn 134, Issue 5, 2008, Pages 743-756

  Kaser, Arthur ^a   Lee, Ann Hwee ^c   Franke, Andre ^d   Glickman, Jonathan N ^b   Zeissig, Sebastian ^a   Tilg, Herbert ^e   Nieuwenhuis, Edward E S ^f   Higgins, Darren E ^b   Schreiber, Stefan ^d,g   Glimcher, Laurie H ^b,c   Blumberg, Richard S ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d UNIVERSITY OF KIEL   (Germany)

^e INSTITUTE FOR MICROELECTRONICS   (Austria)

^f SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^g UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

Author keywords

CELLIMMUNO; HUMDISEASE

Indexed keywords

FLAGELLIN; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; X BOX BINDING PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SPECIFICITY; CELL STRESS; CONTROLLED STUDY; CROHN DISEASE; DISEASE PREDISPOSITION; ENDOPLASMIC RETICULUM STRESS; ENTERITIS; FEMALE; GENE DELETION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; HUMAN TISSUE; INFLAMMATION; INTESTINE EPITHELIUM; INTESTINE EPITHELIUM CELL; MALE; MOUSE; NONHUMAN; PANETH CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; SECRETORY CELL; SINGLE NUCLEOTIDE POLYMORPHISM; ULCERATIVE COLITIS;

BACTERIA (MICROORGANISMS);

EID: 50249086073     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2008.07.021     Document Type: Article

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