Unfolded protein response to autophagy as a promising druggable target for anticancer therapy

Annals of the New York Academy of Sciences

Volumn 1271, Issue 1, 2012, Pages 20-32

  Suh, Dong Hoon ^a   Kim, Mi Kyung ^a   Kim, Hee Seung ^a   Chung, Hyun Hoon ^a   Song, Yong Sang ^a,b,c  

^a Seoul National University College of Medicine   (South Korea)

^b Seoul National University   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

Autophagy; Cancer; Endoplasmic reticulum stress; Molecular targeted therapies; Unfolded protein response

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; AMINOQUINOLINE DERIVATIVE; ANTINEOPLASTIC AGENT; APOPTOSIS SIGNAL REGULATING KINASE 1; BORTEZOMIB; BREFELDIN A; CYTOCHROME C; HEAT SHOCK PROTEIN 90 INHIBITOR; HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE INHIBITOR; HYDROXYCHLOROQUINE; INITIATION FACTOR 2ALPHA; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MONOCLONAL ANTIBODY; PHOSPHOPROTEIN PHOSPHATASE 1; PLANT MEDICINAL PRODUCT; PROTEASOME INHIBITOR; PROTEIN BCL 2; PROTEIN DISULFIDE ISOMERASE; RETASPIMYCIN; STRESS ACTIVATED PROTEIN KINASE; TANESPIMYCIN; THAPSIGARGIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; X BOX BINDING PROTEIN 1;

ANGIOGENESIS; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL; CANCER GROWTH; CELLULAR STRESS RESPONSE; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; HORMONAL THERAPY; HUMAN; INTRACELLULAR SIGNALING; METASTASIS; MITOCHONDRION; MOLECULARLY TARGETED THERAPY; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; RNA TRANSLATION; TRANSCRIPTION INITIATION; UNFOLDED PROTEIN RESPONSE;

EID: 84867363671     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2012.06739.x     Document Type: Article

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