-
1
-
-
0023852783
-
The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins
-
Kozutsumi Y., Segal M., Normington K., Gething M.J., Sambrook J. The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins. Nature 1988, 332:462-464.
-
(1988)
Nature
, vol.332
, pp. 462-464
-
-
Kozutsumi, Y.1
Segal, M.2
Normington, K.3
Gething, M.J.4
Sambrook, J.5
-
2
-
-
0032101239
-
The unfolded protein response: an intracellular signalling pathway with many surprising features
-
Sidrauski C., Chapman R., Walter P. The unfolded protein response: an intracellular signalling pathway with many surprising features. Trends Cell Biol 1998, 8:245-249.
-
(1998)
Trends Cell Biol
, vol.8
, pp. 245-249
-
-
Sidrauski, C.1
Chapman, R.2
Walter, P.3
-
3
-
-
71949098172
-
Signalling pathways in the unfolded protein response: development from yeast to mammals
-
Mori K. Signalling pathways in the unfolded protein response: development from yeast to mammals. J Biochem 2009, 146:743-750.
-
(2009)
J Biochem
, vol.146
, pp. 743-750
-
-
Mori, K.1
-
4
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
Ron D., Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 2007, 8:519-529.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
5
-
-
70349756962
-
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability
-
Iwawaki T., Akai R., Yamanaka S., Kohno K. Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability. Proc Natl Acad Sci U S A 2009, 106:16657-16662.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 16657-16662
-
-
Iwawaki, T.1
Akai, R.2
Yamanaka, S.3
Kohno, K.4
-
6
-
-
0027465942
-
The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum
-
Kohno K., Normington K., Sambrook J., Gething M.J., Mori K. The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum. Mol Cell Biol 1993, 13:877-890.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 877-890
-
-
Kohno, K.1
Normington, K.2
Sambrook, J.3
Gething, M.J.4
Mori, K.5
-
7
-
-
0033782015
-
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
-
Bertolotti A., Zhang Y., Hendershot L.M., Harding H.P., Ron D. Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response. Nat Cell Biol 2000, 2:326-332.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 326-332
-
-
Bertolotti, A.1
Zhang, Y.2
Hendershot, L.M.3
Harding, H.P.4
Ron, D.5
-
8
-
-
0034694896
-
Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast
-
Okamura K., Kimata Y., Higashio H., Tsuru A., Kohno K. Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast. Biochem Biophys Res Commun 2000, 279:445-450.
-
(2000)
Biochem Biophys Res Commun
, vol.279
, pp. 445-450
-
-
Okamura, K.1
Kimata, Y.2
Higashio, H.3
Tsuru, A.4
Kohno, K.5
-
9
-
-
0038308388
-
Genetic evidence for a role of BiP/Kar2 that regulates Ire1 in response to accumulation of unfolded proteins
-
Kimata Y., Kimata Y.I., Shimizu Y., Abe H., Farcasanu I.C., Takeuchi M., Rose M.D., Kohno K. Genetic evidence for a role of BiP/Kar2 that regulates Ire1 in response to accumulation of unfolded proteins. Mol Biol Cell 2003, 14:2559-2569.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 2559-2569
-
-
Kimata, Y.1
Kimata, Y.I.2
Shimizu, Y.3
Abe, H.4
Farcasanu, I.C.5
Takeuchi, M.6
Rose, M.D.7
Kohno, K.8
-
10
-
-
8444250981
-
A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1
-
Kimata Y., Oikawa D., Shimizu Y., Ishiwata-Kimata Y., Kohno K. A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1. J Cell Biol 2004, 167:445-456.
-
(2004)
J Cell Biol
, vol.167
, pp. 445-456
-
-
Kimata, Y.1
Oikawa, D.2
Shimizu, Y.3
Ishiwata-Kimata, Y.4
Kohno, K.5
-
11
-
-
0036069980
-
ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals
-
Shen J., Chen X., Hendershot L., Prywes R. ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals. Dev Cell 2002, 3:99-111.
-
(2002)
Dev Cell
, vol.3
, pp. 99-111
-
-
Shen, J.1
Chen, X.2
Hendershot, L.3
Prywes, R.4
-
12
-
-
0034896499
-
Unassembled Ig heavy chains do not cycle from BiP in vivo but require light chains to trigger their release
-
Vanhove M., Usherwood Y.K., Hendershot L.M. Unassembled Ig heavy chains do not cycle from BiP in vivo but require light chains to trigger their release. Immunity 2001, 15:105-114.
-
(2001)
Immunity
, vol.15
, pp. 105-114
-
-
Vanhove, M.1
Usherwood, Y.K.2
Hendershot, L.M.3
-
13
-
-
12844257546
-
Stable binding of ATF6 to BiP in the endoplasmic reticulum stress response
-
Shen J., Snapp E.L., Lippincott-Schwartz J., Prywes R. Stable binding of ATF6 to BiP in the endoplasmic reticulum stress response. Mol Cell Biol 2005, 25:921-932.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 921-932
-
-
Shen, J.1
Snapp, E.L.2
Lippincott-Schwartz, J.3
Prywes, R.4
-
14
-
-
33847324367
-
Lobe IB of the ATPase domain of Kar2p/BiP interacts with Ire1p to negatively regulate the unfolded protein response in Saccharomyces cerevisiae
-
Todd-Corlett A., Jones E., Seghers C., Gething M.J. Lobe IB of the ATPase domain of Kar2p/BiP interacts with Ire1p to negatively regulate the unfolded protein response in Saccharomyces cerevisiae. J Mol Biol 2007, 367:770-787.
-
(2007)
J Mol Biol
, vol.367
, pp. 770-787
-
-
Todd-Corlett, A.1
Jones, E.2
Seghers, C.3
Gething, M.J.4
-
15
-
-
26844439863
-
An essential dimer-forming subregion of the endoplasmic reticulum stress sensor Ire1
-
Oikawa D., Kimata Y., Takeuchi M., Kohno K. An essential dimer-forming subregion of the endoplasmic reticulum stress sensor Ire1. Biochem J 2005, 391:135-142.
-
(2005)
Biochem J
, vol.391
, pp. 135-142
-
-
Oikawa, D.1
Kimata, Y.2
Takeuchi, M.3
Kohno, K.4
-
16
-
-
30044432596
-
On the mechanism of sensing unfolded protein in the endoplasmic reticulum
-
Credle J.J., Finer-Moore J.S., Papa F.R., Stroud R.M., Walter P. On the mechanism of sensing unfolded protein in the endoplasmic reticulum. Proc Natl Acad Sci U S A 2005, 102:18773-18784.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 18773-18784
-
-
Credle, J.J.1
Finer-Moore, J.S.2
Papa, F.R.3
Stroud, R.M.4
Walter, P.5
-
17
-
-
35348967427
-
Two regulatory steps of ER-stress sensor Ire1 involving its cluster formation and interaction with unfolded proteins
-
Kimata Y., Ishiwata-Kimata Y., Ito T., Hirata A., Suzuki T., Oikawa D., Takeuchi M., Kohno K. Two regulatory steps of ER-stress sensor Ire1 involving its cluster formation and interaction with unfolded proteins. J Cell Biol 2007, 179:75-86.
-
(2007)
J Cell Biol
, vol.179
, pp. 75-86
-
-
Kimata, Y.1
Ishiwata-Kimata, Y.2
Ito, T.3
Hirata, A.4
Suzuki, T.5
Oikawa, D.6
Takeuchi, M.7
Kohno, K.8
-
18
-
-
59649092854
-
Messenger RNA targeting to endoplasmic reticulum stress signalling sites
-
Aragon T., van Anken E., Pincus D., Serafimova I.M., Korennykh A.V., Rubio C.A., Walter P. Messenger RNA targeting to endoplasmic reticulum stress signalling sites. Nature 2009, 457:736-740.
-
(2009)
Nature
, vol.457
, pp. 736-740
-
-
Aragon, T.1
van Anken, E.2
Pincus, D.3
Serafimova, I.M.4
Korennykh, A.V.5
Rubio, C.A.6
Walter, P.7
-
19
-
-
59649111087
-
The unfolded protein response signals through high-order assembly of Ire1
-
Korennykh A.V., Egea P.F., Korostelev A.A., Finer-Moore J., Zhang C., Shokat K.M., Stroud R.M., Walter P. The unfolded protein response signals through high-order assembly of Ire1. Nature 2009, 457:687-693.
-
(2009)
Nature
, vol.457
, pp. 687-693
-
-
Korennykh, A.V.1
Egea, P.F.2
Korostelev, A.A.3
Finer-Moore, J.4
Zhang, C.5
Shokat, K.M.6
Stroud, R.M.7
Walter, P.8
-
20
-
-
34249707984
-
Self-association and BiP dissociation are not sufficient for activation of the ER stress sensor Ire1
-
Oikawa D., Kimata Y., Kohno K. Self-association and BiP dissociation are not sufficient for activation of the ER stress sensor Ire1. J Cell Sci 2007, 120:1681-1688.
-
(2007)
J Cell Sci
, vol.120
, pp. 1681-1688
-
-
Oikawa, D.1
Kimata, Y.2
Kohno, K.3
-
21
-
-
67651045789
-
Activation of mammalian IRE1alpha upon ER stress depends on dissociation of BiP rather than on direct interaction with unfolded proteins
-
Oikawa D., Kimata Y., Kohno K., Iwawaki T. Activation of mammalian IRE1alpha upon ER stress depends on dissociation of BiP rather than on direct interaction with unfolded proteins. Exp Cell Res 2009, 315:2496-2504.
-
(2009)
Exp Cell Res
, vol.315
, pp. 2496-2504
-
-
Oikawa, D.1
Kimata, Y.2
Kohno, K.3
Iwawaki, T.4
-
22
-
-
0037166237
-
Dimerization and release of molecular chaperone inhibition facilitate activation of eukaryotic initiation factor-2 kinase in response to endoplasmic reticulum stress
-
Ma K., Vattem K.M., Wek R.C. Dimerization and release of molecular chaperone inhibition facilitate activation of eukaryotic initiation factor-2 kinase in response to endoplasmic reticulum stress. J Biol Chem 2002, 277:18728-18735.
-
(2002)
J Biol Chem
, vol.277
, pp. 18728-18735
-
-
Ma, K.1
Vattem, K.M.2
Wek, R.C.3
-
23
-
-
33749233991
-
The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response
-
Zhou J., Liu C.Y., Back S.H., Clark R.L., Peisach D., Xu Z., Kaufman R.J. The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response. Proc Natl Acad Sci U S A 2006, 103:14343-14348.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 14343-14348
-
-
Zhou, J.1
Liu, C.Y.2
Back, S.H.3
Clark, R.L.4
Peisach, D.5
Xu, Z.6
Kaufman, R.J.7
-
24
-
-
0034637605
-
Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulum
-
Liu C.Y., Schroder M., Kaufman R.J. Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulum. J Biol Chem 2000, 275:24881-24885.
-
(2000)
J Biol Chem
, vol.275
, pp. 24881-24885
-
-
Liu, C.Y.1
Schroder, M.2
Kaufman, R.J.3
-
25
-
-
77950887221
-
Flavonol activation defines an unanticipated ligand-binding site in the kinase-RNase domain of IRE1
-
Wiseman R.L., Zhang Y., Lee K.P., Harding H.P., Haynes C.M., Price J., Sicheri F., Ron D. Flavonol activation defines an unanticipated ligand-binding site in the kinase-RNase domain of IRE1. Mol Cell 2009, 38:291-304.
-
(2009)
Mol Cell
, vol.38
, pp. 291-304
-
-
Wiseman, R.L.1
Zhang, Y.2
Lee, K.P.3
Harding, H.P.4
Haynes, C.M.5
Price, J.6
Sicheri, F.7
Ron, D.8
-
26
-
-
33646237823
-
Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha
-
Hetz C., Bernasconi P., Fisher J., Lee A.H., Bassik M.C., Antonsson B., Brandt G.S., Iwakoshi N.N., Schinzel A., Glimcher L.H., Korsmeyer S.J. Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha. Science 2006, 312:572-576.
-
(2006)
Science
, vol.312
, pp. 572-576
-
-
Hetz, C.1
Bernasconi, P.2
Fisher, J.3
Lee, A.H.4
Bassik, M.C.5
Antonsson, B.6
Brandt, G.S.7
Iwakoshi, N.N.8
Schinzel, A.9
Glimcher, L.H.10
Korsmeyer, S.J.11
-
27
-
-
45549103421
-
AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response
-
Luo D., He Y., Zhang H., Yu L., Chen H., Xu Z., Tang S., Urano F., Min W. AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response. J Biol Chem 2008, 283:11905-11912.
-
(2008)
J Biol Chem
, vol.283
, pp. 11905-11912
-
-
Luo, D.1
He, Y.2
Zhang, H.3
Yu, L.4
Chen, H.5
Xu, Z.6
Tang, S.7
Urano, F.8
Min, W.9
-
28
-
-
0034724520
-
Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation
-
Travers K.J., Patil C.K., Wodicka L., Lockhart D.J., Weissman J.S., Walter P. Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation. Cell 2000, 101:249-258.
-
(2000)
Cell
, vol.101
, pp. 249-258
-
-
Travers, K.J.1
Patil, C.K.2
Wodicka, L.3
Lockhart, D.J.4
Weissman, J.S.5
Walter, P.6
-
29
-
-
33645866473
-
Yeast unfolded protein response pathway regulates expression of genes for anti-oxidative stress and for cell surface proteins
-
Kimata Y., Ishiwata-Kimata Y., Yamada S., Kohno K. Yeast unfolded protein response pathway regulates expression of genes for anti-oxidative stress and for cell surface proteins. Genes Cells 2006, 11:59-69.
-
(2006)
Genes Cells
, vol.11
, pp. 59-69
-
-
Kimata, Y.1
Ishiwata-Kimata, Y.2
Yamada, S.3
Kohno, K.4
-
30
-
-
3142658576
-
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation
-
Shaffer A.L., Shapiro-Shelef M., Iwakoshi N.N., Lee A.H., Qian S.B., Zhao H., Yu X., Yang L., Tan B.K., Rosenwald A., Hurt E.M., Petroulakis E., Sonenberg N., Yewdell J.W., Calame K., Glimcher L.H., Staudt L.M. XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. Immunity 2004, 21:81-93.
-
(2004)
Immunity
, vol.21
, pp. 81-93
-
-
Shaffer, A.L.1
Shapiro-Shelef, M.2
Iwakoshi, N.N.3
Lee, A.H.4
Qian, S.B.5
Zhao, H.6
Yu, X.7
Yang, L.8
Tan, B.K.9
Rosenwald, A.10
Hurt, E.M.11
Petroulakis, E.12
Sonenberg, N.13
Yewdell, J.W.14
Calame, K.15
Glimcher, L.H.16
Staudt, L.M.17
-
31
-
-
5444222234
-
XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum
-
Sriburi R., Jackowski S., Mori K., Brewer J.W. XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum. J Cell Biol 2004, 167:35-41.
-
(2004)
J Cell Biol
, vol.167
, pp. 35-41
-
-
Sriburi, R.1
Jackowski, S.2
Mori, K.3
Brewer, J.W.4
-
32
-
-
0030879870
-
The unfolded protein response coordinates the production of endoplasmic reticulum protein and endoplasmic reticulum membrane
-
Cox J.S., Chapman R.E., Walter P. The unfolded protein response coordinates the production of endoplasmic reticulum protein and endoplasmic reticulum membrane. Mol Biol Cell 1997, 8:1805-1814.
-
(1997)
Mol Biol Cell
, vol.8
, pp. 1805-1814
-
-
Cox, J.S.1
Chapman, R.E.2
Walter, P.3
-
33
-
-
63449128473
-
Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum
-
Jonikas M.C., Collins S.R., Denic V., Oh E., Quan E.M., Schmid V., Weibezahn J., Schwappach B., Walter P., Weissman J.S., Schuldiner M. Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science 2009, 323:1693-1697.
-
(2009)
Science
, vol.323
, pp. 1693-1697
-
-
Jonikas, M.C.1
Collins, S.R.2
Denic, V.3
Oh, E.4
Quan, E.M.5
Schmid, V.6
Weibezahn, J.7
Schwappach, B.8
Walter, P.9
Weissman, J.S.10
Schuldiner, M.11
-
34
-
-
65749089838
-
Lipid-induced ER stress: synergistic effects of sterols and saturated fatty acids
-
Pineau L., Colas J., Dupont S., Beney L., Fleurat-Lessard P., Berjeaud J.M., Berges T., Ferreira T. Lipid-induced ER stress: synergistic effects of sterols and saturated fatty acids. Traffic 2009, 10:673-690.
-
(2009)
Traffic
, vol.10
, pp. 673-690
-
-
Pineau, L.1
Colas, J.2
Dupont, S.3
Beney, L.4
Fleurat-Lessard, P.5
Berjeaud, J.M.6
Berges, T.7
Ferreira, T.8
-
35
-
-
49649084031
-
Initiation and execution of lipotoxic ER stress in pancreatic beta-cells
-
Cunha D.A., Hekerman P., Ladriere L., Bazarra-Castro A., Ortis F., Wakeham M.C., Moore F., Rasschaert J., Cardozo A.K., Bellomo E., Overbergh L., Mathieu C., Lupi R., Hai T., Herchuelz A., Marchetti P., Rutter G.A., Eizirik D.L., Cnop M. Initiation and execution of lipotoxic ER stress in pancreatic beta-cells. J Cell Sci 2008, 121:2308-2318.
-
(2008)
J Cell Sci
, vol.121
, pp. 2308-2318
-
-
Cunha, D.A.1
Hekerman, P.2
Ladriere, L.3
Bazarra-Castro, A.4
Ortis, F.5
Wakeham, M.C.6
Moore, F.7
Rasschaert, J.8
Cardozo, A.K.9
Bellomo, E.10
Overbergh, L.11
Mathieu, C.12
Lupi, R.13
Hai, T.14
Herchuelz, A.15
Marchetti, P.16
Rutter, G.A.17
Eizirik, D.L.18
Cnop, M.19
-
36
-
-
33846223428
-
Role of disulfide bridges formed in the luminal domain of ATF6 in sensing endoplasmic reticulum stress
-
Nadanaka S., Okada T., Yoshida H., Mori K. Role of disulfide bridges formed in the luminal domain of ATF6 in sensing endoplasmic reticulum stress. Mol Cell Biol 2007, 27:1027-1043.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 1027-1043
-
-
Nadanaka, S.1
Okada, T.2
Yoshida, H.3
Mori, K.4
-
37
-
-
33846187752
-
Reduction of disulfide bridges in the lumenal domain of ATF6 in response to glucose starvation
-
Nadanaka S., Yoshida H., Mori K. Reduction of disulfide bridges in the lumenal domain of ATF6 in response to glucose starvation. Cell Struct Funct 2006, 31:127-134.
-
(2006)
Cell Struct Funct
, vol.31
, pp. 127-134
-
-
Nadanaka, S.1
Yoshida, H.2
Mori, K.3
-
38
-
-
33745590436
-
Intrinsic capacities of molecular sensors of the unfolded protein response to sense alternate forms of endoplasmic reticulum stress
-
DuRose J.B., Tam A.B., Niwa M. Intrinsic capacities of molecular sensors of the unfolded protein response to sense alternate forms of endoplasmic reticulum stress. Mol Biol Cell 2006, 17:3095-3107.
-
(2006)
Mol Biol Cell
, vol.17
, pp. 3095-3107
-
-
DuRose, J.B.1
Tam, A.B.2
Niwa, M.3
-
39
-
-
70449577164
-
In vitro reconstitution of ER-stress induced ATF6 transport in COPII vesicles
-
Schindler A.J., Schekman R. In vitro reconstitution of ER-stress induced ATF6 transport in COPII vesicles. Proc Natl Acad Sci U S A 2009, 106:17775-17780.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 17775-17780
-
-
Schindler, A.J.1
Schekman, R.2
-
40
-
-
35748975933
-
Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation
-
Tsukumo Y., Tomida A., Kitahara O., Nakamura Y., Asada S., Mori K., Tsuruo T. Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation. J Biol Chem 2007, 282:29264-29272.
-
(2007)
J Biol Chem
, vol.282
, pp. 29264-29272
-
-
Tsukumo, Y.1
Tomida, A.2
Kitahara, O.3
Nakamura, Y.4
Asada, S.5
Mori, K.6
Tsuruo, T.7
-
41
-
-
77949751415
-
Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells
-
Fonseca S.G., Ishigaki S., Oslowski C.M., Lu S., Lipson K.L., Ghosh R., Hayashi E., Ishihara H., Oka Y., Permutt M.A., Urano F. Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells. J Clin Invest 2010, 120:744-755.
-
(2010)
J Clin Invest
, vol.120
, pp. 744-755
-
-
Fonseca, S.G.1
Ishigaki, S.2
Oslowski, C.M.3
Lu, S.4
Lipson, K.L.5
Ghosh, R.6
Hayashi, E.7
Ishihara, H.8
Oka, Y.9
Permutt, M.A.10
Urano, F.11
-
42
-
-
77955023666
-
BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response
-
Pincus D., Chevalier M.W., Aragon T., van Anken E., Vidal S.E., El-Samad H., Walter P. BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response. PLoS Biol 2010, 8:e1000415.
-
(2010)
PLoS Biol
, vol.8
-
-
Pincus, D.1
Chevalier, M.W.2
Aragon, T.3
van Anken, E.4
Vidal, S.E.5
El-Samad, H.6
Walter, P.7
-
43
-
-
69749123786
-
Fine-tuning of the unfolded protein response: assembling the IRE1alpha interactome
-
Hetz C., Glimcher L.H. Fine-tuning of the unfolded protein response: assembling the IRE1alpha interactome. Mol Cell 2009, 35:551-561.
-
(2009)
Mol Cell
, vol.35
, pp. 551-561
-
-
Hetz, C.1
Glimcher, L.H.2
-
44
-
-
68049110633
-
IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates
-
Han D., Lerner A.G., Vande Walle L., Upton J.P., Xu W., Hagen A., Backes B.J., Oakes S.A., Papa F.R. IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. Cell 2009, 138:562-575.
-
(2009)
Cell
, vol.138
, pp. 562-575
-
-
Han, D.1
Lerner, A.G.2
Vande Walle, L.3
Upton, J.P.4
Xu, W.5
Hagen, A.6
Backes, B.J.7
Oakes, S.A.8
Papa, F.R.9
-
45
-
-
68549092781
-
Regulated Ire1-dependent decay of messenger RNAs in mammalian cells
-
Hollien J., Lin J.H., Li H., Stevens N., Walter P., Weissman J.S. Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. J Cell Biol 2009, 186:323-331.
-
(2009)
J Cell Biol
, vol.186
, pp. 323-331
-
-
Hollien, J.1
Lin, J.H.2
Li, H.3
Stevens, N.4
Walter, P.5
Weissman, J.S.6
-
46
-
-
77951252041
-
Plasma cell differentiation initiates a limited ER stress response by specifically suppressing the PERK-dependent branch of the unfolded protein response
-
Ma Y., Shimizu Y., Mann M.J., Jin Y., Hendershot L.M. Plasma cell differentiation initiates a limited ER stress response by specifically suppressing the PERK-dependent branch of the unfolded protein response. Cell Stress Chaperones 2009, 15:281-293.
-
(2009)
Cell Stress Chaperones
, vol.15
, pp. 281-293
-
-
Ma, Y.1
Shimizu, Y.2
Mann, M.J.3
Jin, Y.4
Hendershot, L.M.5
-
47
-
-
77951290227
-
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages
-
Martinon F., Chen X., Lee A.H., Glimcher L.H. TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. Nat Immunol 2010, 11:411-418.
-
(2010)
Nat Immunol
, vol.11
, pp. 411-418
-
-
Martinon, F.1
Chen, X.2
Lee, A.H.3
Glimcher, L.H.4
-
48
-
-
36049049392
-
IRE1 signaling affects cell fate during the unfolded protein response
-
Lin J.H., Li H., Yasumura D., Cohen H.R., Zhang C., Panning B., Shokat K.M., Lavail M.M., Walter P. IRE1 signaling affects cell fate during the unfolded protein response. Science 2007, 318:944-949.
-
(2007)
Science
, vol.318
, pp. 944-949
-
-
Lin, J.H.1
Li, H.2
Yasumura, D.3
Cohen, H.R.4
Zhang, C.5
Panning, B.6
Shokat, K.M.7
Lavail, M.M.8
Walter, P.9
-
49
-
-
58449084895
-
Divergent effects of PERK and IRE1 signaling on cell viability
-
Lin J.H., Li H., Zhang Y., Ron D., Walter P. Divergent effects of PERK and IRE1 signaling on cell viability. PLoS One 2009, 4:e4170.
-
(2009)
PLoS One
, vol.4
-
-
Lin, J.H.1
Li, H.2
Zhang, Y.3
Ron, D.4
Walter, P.5
-
50
-
-
62549129467
-
BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha
-
Lisbona F., Rojas-Rivera D., Thielen P., Zamorano S., Todd D., Martinon F., Glavic A., Kress C., Lin J.H., Walter P., Reed J.C., Glimcher L.H., Hetz C. BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha. Mol Cell 2009, 33:679-691.
-
(2009)
Mol Cell
, vol.33
, pp. 679-691
-
-
Lisbona, F.1
Rojas-Rivera, D.2
Thielen, P.3
Zamorano, S.4
Todd, D.5
Martinon, F.6
Glavic, A.7
Kress, C.8
Lin, J.H.9
Walter, P.10
Reed, J.C.11
Glimcher, L.H.12
Hetz, C.13
-
51
-
-
77951645463
-
A crucial role for RACK1 in the regulation of glucose-stimulated IRE1alpha activation in pancreatic beta cells
-
Qiu Y., Mao T., Zhang Y., Shao M., You J., Ding Q., Chen Y., Wu D., Xie D., Lin X., Gao X., Kaufman R.J., Li W., Liu Y. A crucial role for RACK1 in the regulation of glucose-stimulated IRE1alpha activation in pancreatic beta cells. Sci Signal 2010, 3:ra7.
-
(2010)
Sci Signal
, vol.3
-
-
Qiu, Y.1
Mao, T.2
Zhang, Y.3
Shao, M.4
You, J.5
Ding, Q.6
Chen, Y.7
Wu, D.8
Xie, D.9
Lin, X.10
Gao, X.11
Kaufman, R.J.12
Li, W.13
Liu, Y.14
-
52
-
-
77953153048
-
Regulation of basal cellular physiology by the homeostatic unfolded protein response
-
Rutkowski D.T., Hegde R.S. Regulation of basal cellular physiology by the homeostatic unfolded protein response. J Cell Biol 2010, 189:783-794.
-
(2010)
J Cell Biol
, vol.189
, pp. 783-794
-
-
Rutkowski, D.T.1
Hegde, R.S.2
|