Hsp90 molecular chaperone inhibitors: Are we there yet?

Clinical Cancer Research

Volumn 18, Issue 1, 2012, Pages 64-76

  Neckers, Len ^a   Workman, Paul ^b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

5 (2,4 DIHYDROXY 5 ISOPROPYLPHENYL) 4 (4 MORPHOLINOMETHYLPHENYL) 3 ISOXAZOLECARBOXYLIC ACID ETHYLAMIDE; ADENOSINE TRIPHOSPHATE; ALVESPIMYCIN; AT 13387; BIIB 021; BORTEZOMIB; CHAPERONE; CRIZOTINIB; CUDC 305; EPHRIN A2; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GANETESPIB; GELDANAMYCIN; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90 INHIBITOR; HEAT SHOCK TRANSCRIPTION FACTOR 1; IMATINIB; KW 2478; NVP BEP 800; ONCOPROTEIN; PUH 71; RADICICOL; RETASPIMYCIN; SNX 5422; TANESPIMYCIN; TRANSCRIPTION FACTOR; TRASTUZUMAB; UNCLASSIFIED DRUG; UNINDEXED DRUG; XL 888;

ALK GENE; AMINO TERMINAL SEQUENCE; ANTINEOPLASTIC ACTIVITY; BRAF GENE; BRAIN TUMOR; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CASTRATION RESISTANT PROSTATE CANCER; CELL CYCLE ARREST; CELL SURVIVAL; CELLULAR STRESS RESPONSE; CHEMOSENSITIVITY; CHONDROSARCOMA; CHRONIC MYELOID LEUKEMIA; COLON CANCER; DIARRHEA; DRUG CYTOTOXICITY; DRUG DEPENDENCE; DRUG EFFICACY; DRUG INDUSTRY; DRUG RESEARCH; DRUG STRUCTURE; DRUG TARGETING; EGFR GENE; FATIGUE; GASTROINTESTINAL STROMAL TUMOR; HEADACHE; HUMAN; HYPERTRANSAMINASEMIA; INHIBITION KINETICS; KIDNEY CANCER; LIVER DISEASE; LUNG NON SMALL CELL CANCER; MALIGNANT NEOPLASTIC DISEASE; MALIGNANT TRANSFORMATION; MELANOMA; MULTIPLE MYELOMA; NAUSEA; NEUROPATHY; NONHUMAN; ONCOGENE; ONCOGENE NEU; OVARY CANCER; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN HYDROLYSIS; PROTEIN STRUCTURE; REVIEW;

ANIMALS; ANTINEOPLASTIC AGENTS; CLINICAL TRIALS AS TOPIC; DRUG EVALUATION, PRECLINICAL; HSP90 HEAT-SHOCK PROTEINS; HUMANS; NEOPLASMS;

EID: 84855457952     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-11-1000     Document Type: Review

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