-
1
-
-
0027305620
-
A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus
-
Mori,K., Ma,W., Gething,M.J. and Sambrook,J. (1993) A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus. Cell, 74, 743-756.
-
(1993)
Cell
, vol.74
, pp. 743-756
-
-
Mori, K.1
Ma, W.2
Gething, M.J.3
Sambrook, J.4
-
2
-
-
0027324844
-
Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase
-
Cox,J.S., Shamu,C.E. and Walter,P. (1993) Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase. Cell, 73, 1197-1206.
-
(1993)
Cell
, vol.73
, pp. 1197-1206
-
-
Cox, J.S.1
Shamu, C.E.2
Walter, P.3
-
3
-
-
22244446505
-
The mammalian unfolded protein response
-
Schroder,M. and Kaufman,R.J. (2005) The mammalian unfolded protein response. Annu. Rev. Biochem., 74, 739-789.
-
(2005)
Annu. Rev. Biochem.
, vol.74
, pp. 739-789
-
-
Schroder, M.1
Kaufman, R.J.2
-
4
-
-
0030954870
-
The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response
-
Sidrauski,C. and Walter,P. (1997) The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response. Cell, 90, 1031-1039.
-
(1997)
Cell
, vol.90
, pp. 1031-1039
-
-
Sidrauski, C.1
Walter, P.2
-
5
-
-
0026628290
-
A 22bp cis-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins
-
Mori,K., Sant,A., Kohno,K., Normington,K., Gething,M.J. and Sambrook,J. (1992) A 22bp cis-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins. EMBO J., 11, 2583-2593.
-
(1992)
EMBO J
, vol.11
, pp. 2583-2593
-
-
Mori, K.1
Sant, A.2
Kohno, K.3
Normington, K.4
Gething, M.J.5
Sambrook, J.6
-
6
-
-
0027465942
-
The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum
-
Kohno,K., Normington,K., Sambrook,J., Gething,M.J. and Mori,K. (1993) The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum. Mol. Cell Biol., 13, 877-890.
-
(1993)
Mol. Cell Biol.
, vol.13
, pp. 877-890
-
-
Kohno, K.1
Normington, K.2
Sambrook, J.3
Gething, M.J.4
Mori, K.5
-
7
-
-
0032525990
-
A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells
-
Tirasophon,W., Welihinda,A.A. and Kaufman,R.J. (1998) A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells. Genes Dev., 12, 1812-1824.
-
(1998)
Genes Dev.
, vol.12
, pp. 1812-1824
-
-
Tirasophon, W.1
Welihinda, A.A.2
Kaufman, R.J.3
-
8
-
-
0032190546
-
Cloning of mammalian Ire1 reveals diversity in the ER stress responses
-
Wang,X.Z., Harding,H.P., Zhang,Y., Jolicoeur,E.M., Kuroda,M. and Ron,D. (1998) Cloning of mammalian Ire1 reveals diversity in the ER stress responses. EMBO J., 17, 5708-5717.
-
(1998)
EMBO J.
, vol.17
, pp. 5708-5717
-
-
Wang, X.Z.1
Harding, H.P.2
Zhang, Y.3
Jolicoeur, E.M.4
Kuroda, M.5
Ron, D.6
-
9
-
-
0035147411
-
Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress
-
Iwawaki,T., Hosoda,A., Okuda,T., Kamigori,Y., Nomura-Furuwatari,C., Kimata,Y., Tsuru,A. and Kohno,K. (2001) Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress. Nat. Cell Biol., 3, 158-164.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 158-164
-
-
Iwawaki, T.1
Hosoda, A.2
Okuda, T.3
Kamigori, Y.4
Nomura-Furuwatari, C.5
Kimata, Y.6
Tsuru, A.7
Kohno, K.8
-
10
-
-
0035094262
-
Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice
-
Bertolotti,A., Wang,X., Novoa,I., Jungreis,R., Schlessinger,K., Cho,J.H., West,A.B. and Ron,D. (2001) Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice. J. Clin. Invest., 107, 585-593.
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 585-593
-
-
Bertolotti, A.1
Wang, X.2
Novoa, I.3
Jungreis, R.4
Schlessinger, K.5
Cho, J.H.6
West, A.B.7
Ron, D.8
-
11
-
-
0033782015
-
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
-
Bertolotti,A., Zhang,Y., Hendershot,L.M., Harding,H.P. and Ron,D. (2000) Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response. Nat. Cell Biol., 2, 326-332.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 326-332
-
-
Bertolotti, A.1
Zhang, Y.2
Hendershot, L.M.3
Harding, H.P.4
Ron, D.5
-
12
-
-
67651045789
-
Activation of mammalian IRE1alpha upon ER stress depends on dissociation of BiP rather than on direct interaction with unfolded proteins
-
Oikawa,D., Kimata,Y., Kohno,K. and Iwawaki,T. (2009) Activation of mammalian IRE1alpha upon ER stress depends on dissociation of BiP rather than on direct interaction with unfolded proteins. Exp. Cell Res., 315, 2496-2504.
-
(2009)
Exp. Cell Res.
, vol.315
, pp. 2496-2504
-
-
Oikawa, D.1
Kimata, Y.2
Kohno, K.3
Iwawaki, T.4
-
13
-
-
0035966269
-
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
-
Yoshida,H., Matsui,T., Yamamoto,A., Okada,T. and Mori,K. (2001) XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell, 107, 881-891.
-
(2001)
Cell
, vol.107
, pp. 881-891
-
-
Yoshida, H.1
Matsui, T.2
Yamamoto, A.3
Okada, T.4
Mori, K.5
-
14
-
-
0037011917
-
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
-
Calfon,M., Zeng,H., Urano,F., Till,J.H., Hubbard,S.R., Harding,H.P., Clark,S.G. and Ron,D. (2002) IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature, 415, 92-96.
-
(2002)
Nature
, vol.415
, pp. 92-96
-
-
Calfon, M.1
Zeng, H.2
Urano, F.3
Till, J.H.4
Hubbard, S.R.5
Harding, H.P.6
Clark, S.G.7
Ron, D.8
-
15
-
-
33745820796
-
Cytoplasmic IRE1alpha-mediated XBP1 mRNA splicing in the absence of nuclear processing and endoplasmic reticulum stress
-
Back,S.H., Lee,K., Vink,E. and Kaufman,R.J. (2006) Cytoplasmic IRE1alpha-mediated XBP1 mRNA splicing in the absence of nuclear processing and endoplasmic reticulum stress. J. Biol. Chem., 281, 18691-18706.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 18691-18706
-
-
Back, S.H.1
Lee, K.2
Vink, E.3
Kaufman, R.J.4
-
16
-
-
70350005336
-
Unconventional splicing of XBP1 mRNA occurs in the cytoplasm during the mammalian unfolded protein response
-
Uemura,A., Oku,M., Mori,K. and Yoshida,H. (2009) Unconventional splicing of XBP1 mRNA occurs in the cytoplasm during the mammalian unfolded protein response. J. Cell Sci., 122, 2877-2886.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 2877-2886
-
-
Uemura, A.1
Oku, M.2
Mori, K.3
Yoshida, H.4
-
17
-
-
64749103329
-
Cotranslational targeting of XBP1 protein to the membrane promotes cytoplasmic splicing of its own mRNA
-
Yanagitani,K., Imagawa,Y., Iwawaki,T., Hosoda,A., Saito,M., Kimata,Y. and Kohno,K. (2009) Cotranslational targeting of XBP1 protein to the membrane promotes cytoplasmic splicing of its own mRNA. Mol. Cell, 34, 191-200.
-
(2009)
Mol. Cell
, vol.34
, pp. 191-200
-
-
Yanagitani, K.1
Imagawa, Y.2
Iwawaki, T.3
Hosoda, A.4
Saito, M.5
Kimata, Y.6
Kohno, K.7
-
18
-
-
33749624512
-
Analysis of the XBP1 splicing mechanism using endoplasmic reticulum stress-indicators
-
Iwawaki,T. and Akai,R. (2006) Analysis of the XBP1 splicing mechanism using endoplasmic reticulum stress-indicators. Biochem. Biophys. Res. Commun., 350, 709-715.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.350
, pp. 709-715
-
-
Iwawaki, T.1
Akai, R.2
-
19
-
-
23644433913
-
Genome-scale approaches for discovering novel nonconventional splicing substrates of the Ire1 nuclease
-
Niwa,M., Patil,C.K., DeRisi,J. and Walter,P. (2005) Genome-scale approaches for discovering novel nonconventional splicing substrates of the Ire1 nuclease. Genome Biol., 6, R3.
-
(2005)
Genome Biol
, vol.6
-
-
Niwa, M.1
Patil, C.K.2
DeRisi, J.3
Walter, P.4
-
20
-
-
33745606008
-
Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans
-
Shen,X., Ellis,R.E., Sakaki,K. and Kaufman,R.J. (2005) Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans. PLoS Genet., 1, e37.
-
(2005)
PLoS Genet
, vol.1
-
-
Shen, X.1
Ellis, R.E.2
Sakaki, K.3
Kaufman, R.J.4
-
21
-
-
14944371187
-
The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis
-
Zhang,K., Wong,H.N., Song,B., Miller,C.N., Scheuner,D. and Kaufman,R.J. (2005) The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis. J. Clin. Invest., 115, 268-281.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 268-281
-
-
Zhang, K.1
Wong, H.N.2
Song, B.3
Miller, C.N.4
Scheuner, D.5
Kaufman, R.J.6
-
22
-
-
33745893809
-
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response
-
Hollien,J. and Weissman,J.S. (2006) Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Science, 313, 104-107.
-
(2006)
Science
, vol.313
, pp. 104-107
-
-
Hollien, J.1
Weissman, J.S.2
-
23
-
-
0034312290
-
The endoribonuclease activity of mammalian IRE1 autoregulates its mRNA and is required for the unfolded protein response
-
Tirasophon,W., Lee,K., Callaghan,B., Welihinda,A. and Kaufman,R.J. (2000) The endoribonuclease activity of mammalian IRE1 autoregulates its mRNA and is required for the unfolded protein response. Genes Dev., 14, 2725-2736.
-
(2000)
Genes Dev
, vol.14
, pp. 2725-2736
-
-
Tirasophon, W.1
Lee, K.2
Callaghan, B.3
Welihinda, A.4
Kaufman, R.J.5
-
24
-
-
34250882716
-
Site-specific cleavage of CD59 mRNA by endoplasmic reticulum-localized ribonuclease, IRE1
-
Oikawa,D., Tokuda,M. and Iwawaki,T. (2007) Site-specific cleavage of CD59 mRNA by endoplasmic reticulum-localized ribonuclease, IRE1. Biochem. Biophys. Res. Commun., 360, 122-127.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.360
, pp. 122-127
-
-
Oikawa, D.1
Tokuda, M.2
Iwawaki, T.3
-
25
-
-
68049110633
-
IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates
-
Han,D., Lerner,A.G., Vande Walle,L., Upton,J.P., Xu,W., Hagen,A., Backes,B.J., Oakes,S.A. and Papa,F.R. (2009) IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. Cell, 138, 562-575.
-
(2009)
Cell
, vol.138
, pp. 562-575
-
-
Han, D.1
Lerner, A.G.2
Vande Walle, L.3
Upton, J.P.4
Xu, W.5
Hagen, A.6
Backes, B.J.7
Oakes, S.A.8
Papa, F.R.9
-
26
-
-
68549092781
-
Regulated Ire1-dependent decay of messenger RNAs in mammalian cells
-
Hollien,J., Lin,J.H., Li,H., Stevens,N., Walter,P. and Weissman,J.S. (2009) Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. J. Cell Biol., 186, 323-331.
-
(2009)
J. Cell Biol.
, vol.186
, pp. 323-331
-
-
Hollien, J.1
Lin, J.H.2
Li, H.3
Stevens, N.4
Walter, P.5
Weissman, J.S.6
-
27
-
-
45749114525
-
The role of IRE1alpha in the degradation of insulin mRNA in pancreatic beta-cells
-
Lipson,K.L., Ghosh,R. and Urano,F. (2008) The role of IRE1alpha in the degradation of insulin mRNA in pancreatic beta-cells. PLoS One, 3, e1648.
-
(2008)
PLoS One
, vol.3
-
-
Lipson, K.L.1
Ghosh, R.2
Urano, F.3
-
28
-
-
42649125586
-
IRE1beta inhibits chylomicron production by selectively degrading MTP mRNA
-
Iqbal,J., Dai,K., Seimon,T., Jungreis,R., Oyadomari,M., Kuriakose,G., Ron,D., Tabas,I. and Hussain,M.M. (2008) IRE1beta inhibits chylomicron production by selectively degrading MTP mRNA. Cell Metab., 7, 445-455.
-
(2008)
Cell Metab
, vol.7
, pp. 445-455
-
-
Iqbal, J.1
Dai, K.2
Seimon, T.3
Jungreis, R.4
Oyadomari, M.5
Kuriakose, G.6
Ron, D.7
Tabas, I.8
Hussain, M.M.9
-
29
-
-
70349756962
-
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability
-
Iwawaki,T., Akai,R., Yamanaka,S. and Kohno,K. (2009) Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability. Proc. Natl Acad. Sci. USA, 106, 16657-16662.
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 16657-16662
-
-
Iwawaki, T.1
Akai, R.2
Yamanaka, S.3
Kohno, K.4
|