-
1
-
-
0035913294
-
Plasma cell differentiation requires transcription factor XBP-1
-
Reimold, A.M., N.N. Iwakoshi, J. Manis, P. Vallabhajosyula, E. Szomolanyi-Tsuda, E.M. Gravallese, D. Friend, M.J. Grusby, F. Alt, and L.H. Glimcher. 2001. Plasma cell differentiation requires transcription factor XBP-1. Nature. 412:300-307.
-
(2001)
Nature
, vol.412
, pp. 300-307
-
-
Reimold, A.M.1
Iwakoshi, N.N.2
Manis, J.3
Vallabhajosyula, P.4
Szomolanyi-Tsuda, E.5
Gravallese, E.M.6
Friend, D.7
Grusby, M.J.8
Alt, F.9
Glimcher, L.H.10
-
2
-
-
33747849846
-
Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1
-
Lipson, K.L., S.G. Fonseca, S. Ishigaki, L.X. Nguyen, E. Foss, R. Bortell, A.A. Rossini, and F. Urano. 2006. Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1. Cell Metab. 4:245-254.
-
(2006)
Cell Metab
, vol.4
, pp. 245-254
-
-
Lipson, K.L.1
Fonseca, S.G.2
Ishigaki, S.3
Nguyen, L.X.4
Foss, E.5
Bortell, R.6
Rossini, A.A.7
Urano, F.8
-
3
-
-
33646167400
-
ER stress, hypoxia tolerance and tumor progression
-
Koumenis, C. 2006. ER stress, hypoxia tolerance and tumor progression. Curr. Mol. Med. 6:55-69.
-
(2006)
Curr. Mol. Med
, vol.6
, pp. 55-69
-
-
Koumenis, C.1
-
4
-
-
24644487812
-
Endoplasmic reticulum stress response and neurodegeneration
-
Paschen, W., and T. Mengesdorf. 2005. Endoplasmic reticulum stress response and neurodegeneration. Cell Calcium. 38:409-415.
-
(2005)
Cell Calcium
, vol.38
, pp. 409-415
-
-
Paschen, W.1
Mengesdorf, T.2
-
5
-
-
0025320560
-
A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter
-
Liou, H.C., M.R. Boothby, P.W. Finn, R. Davidon, N. Nabavi, N.J. Zeleznik-Le, J.P. Ting, and L.H. Glimcher. 1990. A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter. Science. 247:1581-1584.
-
(1990)
Science
, vol.247
, pp. 1581-1584
-
-
Liou, H.C.1
Boothby, M.R.2
Finn, P.W.3
Davidon, R.4
Nabavi, N.5
Zeleznik-Le, N.J.6
Ting, J.P.7
Glimcher, L.H.8
-
6
-
-
18244405070
-
-
Shen, X., R.E. Ellis, K. Lee, C.Y. Liu, K. Yang, A. Solomon, H. Yoshida, R. Morimoto, D.M. Kurnit, K. Mori, and R.J. Kaufman. 2001. Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development. Cell. 107:893-903.
-
Shen, X., R.E. Ellis, K. Lee, C.Y. Liu, K. Yang, A. Solomon, H. Yoshida, R. Morimoto, D.M. Kurnit, K. Mori, and R.J. Kaufman. 2001. Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development. Cell. 107:893-903.
-
-
-
-
7
-
-
0035966269
-
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
-
Yoshida, H., T. Matsui, A. Yamamoto, T. Okada, and K. Mori. 2001. XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell. 107:881-891.
-
(2001)
Cell
, vol.107
, pp. 881-891
-
-
Yoshida, H.1
Matsui, T.2
Yamamoto, A.3
Okada, T.4
Mori, K.5
-
8
-
-
0037011917
-
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
-
Calfon, M., H. Zeng, F. Urano, J.H. Till, S.R. Hubbard, H.P. Harding, S.G. Clark, and D. Ron. 2002. IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature. 415:92-96.
-
(2002)
Nature
, vol.415
, pp. 92-96
-
-
Calfon, M.1
Zeng, H.2
Urano, F.3
Till, J.H.4
Hubbard, S.R.5
Harding, H.P.6
Clark, S.G.7
Ron, D.8
-
9
-
-
0034650851
-
An essential role in liver development for transcription factor XBP-1
-
Reimold, A.M., A. Etkin, I. Clauss, A. Perkins, D.S. Friend, J. Zhang, H.F. Horton, A. Scott, S.H. Orkin, M.C. Byrne, et al. 2000. An essential role in liver development for transcription factor XBP-1. Genes Dev. 14:152-157.
-
(2000)
Genes Dev
, vol.14
, pp. 152-157
-
-
Reimold, A.M.1
Etkin, A.2
Clauss, I.3
Perkins, A.4
Friend, D.S.5
Zhang, J.6
Horton, H.F.7
Scott, A.8
Orkin, S.H.9
Byrne, M.C.10
-
10
-
-
29244448729
-
XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands
-
Lee, A.H., G.C. Chu, N.N. Iwakoshi, and L.H. Glimcher. 2005. XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands. EMBO J. 24:4368-4380.
-
(2005)
EMBO J
, vol.24
, pp. 4368-4380
-
-
Lee, A.H.1
Chu, G.C.2
Iwakoshi, N.N.3
Glimcher, L.H.4
-
11
-
-
0037385313
-
Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1
-
Iwakoshi, N.N., A.H. Lee, P. Vallabhajosyula, K.L. Otipoby, K. Rajewsky, and L.H. Glimcher. 2003. Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1. Nat. Immunol. 4:321-329.
-
(2003)
Nat. Immunol
, vol.4
, pp. 321-329
-
-
Iwakoshi, N.N.1
Lee, A.H.2
Vallabhajosyula, P.3
Otipoby, K.L.4
Rajewsky, K.5
Glimcher, L.H.6
-
12
-
-
0034210658
-
Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells
-
McKenna, H.J., K.L. Stocking, R.E. Miller, K. Brasel, T. De Smedt, E. Maraskovsky, C.R. Maliszewski, D.H. Lynch, J. Smith, B. Pulendran, et al. 2000. Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells. Blood. 95:3489-3497.
-
(2000)
Blood
, vol.95
, pp. 3489-3497
-
-
McKenna, H.J.1
Stocking, K.L.2
Miller, R.E.3
Brasel, K.4
De Smedt, T.5
Maraskovsky, E.6
Maliszewski, C.R.7
Lynch, D.H.8
Smith, J.9
Pulendran, B.10
-
13
-
-
0029661945
-
Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: Multiple dendritic cell subpopulations identified
-
Maraskovsky, E., K. Brasel, M. Teepe, E.R. Roux, S.D. Lyman, K. Shortman, and H.J. McKenna. 1996. Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified. J. Exp. Med. 184:1953-1962.
-
(1996)
J. Exp. Med
, vol.184
, pp. 1953-1962
-
-
Maraskovsky, E.1
Brasel, K.2
Teepe, M.3
Roux, E.R.4
Lyman, S.D.5
Shortman, K.6
McKenna, H.J.7
-
14
-
-
10144260007
-
+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF + TNF-α
-
+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF + TNF-α. J. Exp. Med. 184:695-706.
-
(1996)
J. Exp. Med
, vol.184
, pp. 695-706
-
-
Caux, C.1
Vanbervliet, B.2
Massacrier, C.3
Dezutter-Dambuyant, C.4
de Saint-Vis, B.5
Jacquet, C.6
Yoneda, K.7
Imamura, S.8
Schmitt, D.9
Banchereau, J.10
-
15
-
-
0028289244
-
Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and down-regulated by tumor necrosis factor α
-
Sallusto, F., and A. Lanzavecchia. 1994. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and down-regulated by tumor necrosis factor α. J. Exp. Med. 179:1109-1118.
-
(1994)
J. Exp. Med
, vol.179
, pp. 1109-1118
-
-
Sallusto, F.1
Lanzavecchia, A.2
-
16
-
-
33744978765
-
Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment
-
Nagai, Y., K.P. Garrett, S. Ohta, U. Bahrun, T. Kouro, S. Akira, K. Takatsu, and P.W. Kincade. 2006. Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment. Immunity. 24:801-812.
-
(2006)
Immunity
, vol.24
, pp. 801-812
-
-
Nagai, Y.1
Garrett, K.P.2
Ohta, S.3
Bahrun, U.4
Kouro, T.5
Akira, S.6
Takatsu, K.7
Kincade, P.W.8
-
17
-
-
0001722505
-
-
Wu, L., A. D ' Amico, K.D. Winkel, M. Suter, D. Lo, and K. Shortman. 1998. RelB is essential for the development of myeloid-related CD8alpha?dendritic cells but not of lymphoid-related CD8alpha+ dendritic cells. Immunity. 9:839-847.
-
Wu, L., A. D ' Amico, K.D. Winkel, M. Suter, D. Lo, and K. Shortman. 1998. RelB is essential for the development of myeloid-related CD8alpha?dendritic cells but not of lymphoid-related CD8alpha+ dendritic cells. Immunity. 9:839-847.
-
-
-
-
18
-
-
20444466497
-
The transcriptional repressor Gfi1 controls STAT3-dependent dendritic cell development and function
-
Rathinam, C., R. Geffers, R. Yucel, J. Buer, K. Welte, T. Moroy, and C. Klein. 2005. The transcriptional repressor Gfi1 controls STAT3-dependent dendritic cell development and function. Immunity. 22:717-728.
-
(2005)
Immunity
, vol.22
, pp. 717-728
-
-
Rathinam, C.1
Geffers, R.2
Yucel, R.3
Buer, J.4
Welte, K.5
Moroy, T.6
Klein, C.7
-
19
-
-
0037386339
-
Transcriptional profiling identifies Id2 function in dendritic cell development
-
Hacker, C., R.D. Kirsch, X.S. Ju, T. Hieronymus, T.C. Gust, C. Kuhl, T. Jorgas, S.M. Kurz, S. Rose-John, Y. Yokota, and M. Zenke. 2003. Transcriptional profiling identifies Id2 function in dendritic cell development. Nat. Immunol. 4:380-386.
-
(2003)
Nat. Immunol
, vol.4
, pp. 380-386
-
-
Hacker, C.1
Kirsch, R.D.2
Ju, X.S.3
Hieronymus, T.4
Gust, T.C.5
Kuhl, C.6
Jorgas, T.7
Kurz, S.M.8
Rose-John, S.9
Yokota, Y.10
Zenke, M.11
-
20
-
-
14044270784
-
-
Tamura, T., P. Tailor, K. Yamaoka, H.J. Kong, H. Tsujimura, J.J. O ' Shea, H. Singh, and K. Ozato. 2005. IFN regulatory factor-4 and -8 govern dendritic cell subset development and their functional diversity. J. Immunol. 174:2573-2581.
-
Tamura, T., P. Tailor, K. Yamaoka, H.J. Kong, H. Tsujimura, J.J. O ' Shea, H. Singh, and K. Ozato. 2005. IFN regulatory factor-4 and -8 govern dendritic cell subset development and their functional diversity. J. Immunol. 174:2573-2581.
-
-
-
-
21
-
-
0037011021
-
+ dendritic cells
-
+ dendritic cells. J. Exp. Med. 196:1415-1425.
-
(2002)
J. Exp. Med
, vol.196
, pp. 1415-1425
-
-
Schiavoni, G.1
Mattei, F.2
Sestili, P.3
Borghi, P.4
Venditti, M.5
Morse III, H.C.6
Belardelli, F.7
Gabriele, L.8
-
22
-
-
0034651965
-
Transcription factor PU.1 is necessary for development of thymic and myeloid progenitor-derived dendritic cells
-
Anderson, K.L., H. Perkin, C.D. Surh, S. Venturini, R.A. Maki, and B.E. Torbett. 2000. Transcription factor PU.1 is necessary for development of thymic and myeloid progenitor-derived dendritic cells. J. Immunol. 164:1855-1861.
-
(2000)
J. Immunol
, vol.164
, pp. 1855-1861
-
-
Anderson, K.L.1
Perkin, H.2
Surh, C.D.3
Venturini, S.4
Maki, R.A.5
Torbett, B.E.6
-
23
-
-
0347480225
-
STAT3 is required for Flt3L-dependent dendritic cell differentiation
-
Laouar, Y., T. Welte, X.Y. Fu, and R.A. Flavell. 2003. STAT3 is required for Flt3L-dependent dendritic cell differentiation. Immunity. 19:903-912.
-
(2003)
Immunity
, vol.19
, pp. 903-912
-
-
Laouar, Y.1
Welte, T.2
Fu, X.Y.3
Flavell, R.A.4
-
24
-
-
33644518698
-
Towards an understanding of the transcription factor network of dendritic cell development
-
Zenke, M., and T. Hieronymus. 2006. Towards an understanding of the transcription factor network of dendritic cell development. Trends Immunol. 27:140-145.
-
(2006)
Trends Immunol
, vol.27
, pp. 140-145
-
-
Zenke, M.1
Hieronymus, T.2
-
25
-
-
0034614892
-
TRANCE, a tumor necrosis factor family member, enhances the longevity and adjuvant properties of dendritic cells in vivo
-
Josien, R., H.L. Li, E. Ingulli, S. Sarma, B.R. Wong, M. Vologodskaia, R.M. Steinman, and Y. Choi. 2000. TRANCE, a tumor necrosis factor family member, enhances the longevity and adjuvant properties of dendritic cells in vivo. J. Exp. Med. 191:495-502.
-
(2000)
J. Exp. Med
, vol.191
, pp. 495-502
-
-
Josien, R.1
Li, H.L.2
Ingulli, E.3
Sarma, S.4
Wong, B.R.5
Vologodskaia, M.6
Steinman, R.M.7
Choi, Y.8
-
26
-
-
0031439265
-
TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor
-
Wong, B.R., R. Josien, S.Y. Lee, B. Sauter, H.-L. Li, R.M. Steinman, and Y. Choi. 1997. TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor. J. Exp. Med. 186:2075-2080.
-
(1997)
J. Exp. Med
, vol.186
, pp. 2075-2080
-
-
Wong, B.R.1
Josien, R.2
Lee, S.Y.3
Sauter, B.4
Li, H.-L.5
Steinman, R.M.6
Choi, Y.7
-
27
-
-
0036199656
-
Dendritic cell development and survival require distinct NF-κB subunits
-
Ouaaz, F., J. Arron, Y. Zheng, Y. Choi, and A.A. Beg. 2002. Dendritic cell development and survival require distinct NF-κB subunits. Immunity. 16:257-270.
-
(2002)
Immunity
, vol.16
, pp. 257-270
-
-
Ouaaz, F.1
Arron, J.2
Zheng, Y.3
Choi, Y.4
Beg, A.A.5
-
28
-
-
0034254811
-
The PI3 kinase, p38 SAP kinase, and NF-kappaB signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte-derived dendritic cells
-
Ardeshna, K.M., A.R. Pizzey, S. Devereux, and A. Khwaja. 2000. The PI3 kinase, p38 SAP kinase, and NF-kappaB signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte-derived dendritic cells. Blood. 96:1039-1046.
-
(2000)
Blood
, vol.96
, pp. 1039-1046
-
-
Ardeshna, K.M.1
Pizzey, A.R.2
Devereux, S.3
Khwaja, A.4
-
29
-
-
33646237823
-
Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha
-
Hetz, C., P. Bernasconi, J. Fisher, A.H. Lee, M.C. Bassik, B. Antonsson, G.S. Brandt, N.N. Iwakoshi, A. Schinzel, L.H. Glimcher, and S.J. Korsmeyer. 2006. Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha. Science. 312:572-576.
-
(2006)
Science
, vol.312
, pp. 572-576
-
-
Hetz, C.1
Bernasconi, P.2
Fisher, J.3
Lee, A.H.4
Bassik, M.C.5
Antonsson, B.6
Brandt, G.S.7
Iwakoshi, N.N.8
Schinzel, A.9
Glimcher, L.H.10
Korsmeyer, S.J.11
-
30
-
-
17644372733
-
IPC: Professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors
-
Liu, Y.J. 2005. IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors. Annu. Rev. Immunol. 23:275-306.
-
(2005)
Annu. Rev. Immunol
, vol.23
, pp. 275-306
-
-
Liu, Y.J.1
-
31
-
-
16844378439
-
CY15, a malignant histiocytic tumor that is phenotypically similar to immature dendritic cells
-
Kammertoens, T., R. Willebrand, B. Erdmann, L. Li, Y. Li, B. Engels, W. Uckert, and T. Blankenstein. 2005. CY15, a malignant histiocytic tumor that is phenotypically similar to immature dendritic cells. Cancer Res. 65:2560-2564.
-
(2005)
Cancer Res
, vol.65
, pp. 2560-2564
-
-
Kammertoens, T.1
Willebrand, R.2
Erdmann, B.3
Li, L.4
Li, Y.5
Engels, B.6
Uckert, W.7
Blankenstein, T.8
-
32
-
-
3142658576
-
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation
-
Shaffer, A.L., M. Shapiro-Shelef, N.N. Iwakoshi, A.H. Lee, S.B. Qian, H. Zhao, X. Yu, L. Yang, B.K. Tan, A. Rosenwald, et al. 2004. XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. Immunity. 21:81-93.
-
(2004)
Immunity
, vol.21
, pp. 81-93
-
-
Shaffer, A.L.1
Shapiro-Shelef, M.2
Iwakoshi, N.N.3
Lee, A.H.4
Qian, S.B.5
Zhao, H.6
Yu, X.7
Yang, L.8
Tan, B.K.9
Rosenwald, A.10
-
33
-
-
31344441376
-
Activation of the Flt3 signal transduction cascade rescues and enhances type I interferon-producing and dendritic cell development
-
Onai, N., A. Obata-Onai, R. Tussiwand, A. Lanzavecchia, and M.G. Manz. 2006. Activation of the Flt3 signal transduction cascade rescues and enhances type I interferon-producing and dendritic cell development. J. Exp. Med. 203:227-238.
-
(2006)
J. Exp. Med
, vol.203
, pp. 227-238
-
-
Onai, N.1
Obata-Onai, A.2
Tussiwand, R.3
Lanzavecchia, A.4
Manz, M.G.5
-
34
-
-
0036134876
-
Cutting Edge: CpG DNA inhibits dendritic cell apoptosis by up-regulating cellular inhibitor of apoptosis proteins through the phosphatidylinositide-3′-OH kinase pathway
-
Park, Y., S.W. Lee, and Y.C. Sung. 2002. Cutting Edge: CpG DNA inhibits dendritic cell apoptosis by up-regulating cellular inhibitor of apoptosis proteins through the phosphatidylinositide-3′-OH kinase pathway. J. Immunol. 168:5-8.
-
(2002)
J. Immunol
, vol.168
, pp. 5-8
-
-
Park, Y.1
Lee, S.W.2
Sung, Y.C.3
-
35
-
-
0031775746
-
Dendritic cell survival and maturation are regulated by different signaling pathways
-
Rescigno, M., M. Martino, C.L. Sutherland, M.R. Gold, and P. Ricciardi-Castagnoli. 1998. Dendritic cell survival and maturation are regulated by different signaling pathways. J. Exp. Med. 188:2175-2180.
-
(1998)
J. Exp. Med
, vol.188
, pp. 2175-2180
-
-
Rescigno, M.1
Martino, M.2
Sutherland, C.L.3
Gold, M.R.4
Ricciardi-Castagnoli, P.5
-
36
-
-
0043193876
-
Proteasome inhibitors disrupt the unfolded protein response in myeloma cells
-
Lee, A.H., N.N. Iwakoshi, K.C. Anderson, and L.H. Glimcher. 2003. Proteasome inhibitors disrupt the unfolded protein response in myeloma cells. Proc. Natl. Acad. Sci. USA. 100:9946-9951.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 9946-9951
-
-
Lee, A.H.1
Iwakoshi, N.N.2
Anderson, K.C.3
Glimcher, L.H.4
-
37
-
-
0142059951
-
XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response
-
Lee, A.H., N.N. Iwakoshi, and L.H. Glimcher. 2003. XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response. Mol. Cell. Biol. 23:7448-7459.
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 7448-7459
-
-
Lee, A.H.1
Iwakoshi, N.N.2
Glimcher, L.H.3
-
38
-
-
24944452197
-
The adjuvant activity of CpG DNA requires T-bet expression in dendritic cells
-
Lugo-Villarino, G., S.C. Ito, D.M. Klinman, and L.H. Glimcher. 2005. The adjuvant activity of CpG DNA requires T-bet expression in dendritic cells. Proc. Natl. Acad. Sci. USA. 102:13248-13253.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 13248-13253
-
-
Lugo-Villarino, G.1
Ito, S.C.2
Klinman, D.M.3
Glimcher, L.H.4
-
39
-
-
0029828994
-
Transcription factor GATA-3 is required for development of the T-cell lineage
-
Ting, C.N., M.C. Olson, K.P. Barton, and J.M. Leiden. 1996. Transcription factor GATA-3 is required for development of the T-cell lineage. Nature. 384:474-478.
-
(1996)
Nature
, vol.384
, pp. 474-478
-
-
Ting, C.N.1
Olson, M.C.2
Barton, K.P.3
Leiden, J.M.4
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