Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy

Human Molecular Genetics

Volumn 21, Issue 10, 2012, Pages 2245-2262

  Vidal, Rene L ^a,b   Figueroa, Alicia ^a,b   Court, Felipe A ^c   Thielen, Peter ^d   Molina, Claudia ^a,b   Wirth, Craig ^d   Caballero, Benjamin ^e   Kiffin, Roberta ^e   Segura Aguilar, Juan ^b   Cuervo, Ana Maria ^e   Glimcher, Laurie H ^f   Hetz, Claudio ^a,b,d  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSITY OF CHILE   (Chile)

^c PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^e ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^f WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; HUNTINGTIN; TRANSCRIPTION FACTOR FKHR; X BOX BINDING PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CELL SURVIVAL; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; GENE TARGETING; HUNTINGTON CHOREA; MACROAUTOPHAGY; MOTONEURON; MOTOR PERFORMANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; UNFOLDED PROTEIN RESPONSE;

ANIMALS; AUTOPHAGY; CORPUS STRIATUM; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; HUNTINGTON DISEASE; MICE; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; NEURONS; RNA SPLICING; RNA, MESSENGER; TRANSCRIPTION FACTORS; UNFOLDED PROTEIN RESPONSE;

ANIMALIA; MUS; MUS MUSCULUS;

EID: 84860471873     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/dds040     Document Type: Article

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