-
1
-
-
34249672703
-
Biological aging is no longer an unsolved problem
-
DOI 10.1196/annals.1395.001, Biogerontology: Mechanisms and Interventions
-
L. Hayflick Biological aging is no longer an unsolved problem Ann. N. Y. Acad. Sci. 1100 2007 1 13 (Pubitemid 47092635)
-
(2007)
Annals of the New York Academy of Sciences
, vol.1100
, pp. 1-13
-
-
Hayflick, L.1
-
2
-
-
16344387162
-
Aging hearts and vessels: Masters of adaptation and survival
-
DOI 10.1016/j.cardiores.2005.03.004
-
S. Pepe, and E.G. Lakatta Aging hearts and vessels: masters of adaptation and survival Cardiovasc. Res. 66 2005 190 193 (Pubitemid 40471033)
-
(2005)
Cardiovascular Research
, vol.66
, Issue.2
, pp. 190-193
-
-
Pepe, S.1
Lakatta, E.G.2
-
3
-
-
25444523801
-
Arterial aging: Is it an immutable cardiovascular risk factor?
-
DOI 10.1161/01.HYP.0000177474.06749.98
-
S.S. Najjar, A. Scuteri, and E.G. Lakatta Arterial aging: is it an immutable cardiovascular risk factor? Hypertension 46 2005 454 462 (Pubitemid 41376818)
-
(2005)
Hypertension
, vol.46
, Issue.3
, pp. 454-462
-
-
Najjar, S.S.1
Scuteri, A.2
Lakatta, E.G.3
-
4
-
-
84872029837
-
Bringing prevention in geriatrics: Evidences from cardiovascular medicine supporting the new challenge
-
A. Scuteri, and E.G. Lakatta Bringing prevention in geriatrics: evidences from cardiovascular medicine supporting the new challenge Exp. Gerontol. 2012
-
(2012)
Exp. Gerontol.
-
-
Scuteri, A.1
Lakatta, E.G.2
-
5
-
-
80052400687
-
Vascular contributions to cognitive impairment and dementia: A statement for healthcare professionals from the american heart association/american stroke association
-
P.B. Gorelick, A. Scuteri, S.E. Black, C. Decarli, S.M. Greenberg, C. Iadecola, L.J. Launer, S. Laurent, O.L. Lopez, D. Nyenhuis, R.C. Petersen, J.A. Schneider, C. Tzourio, D.K. Arnett, D.A. Bennett, H.C. Chui, R.T. Higashida, R. Lindquist, P.M. Nilsson, G.C. Roman, F.W. Sellke, and S. Seshadri Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association Stroke 42 2011 2672 2713
-
(2011)
Stroke
, vol.42
, pp. 2672-2713
-
-
Gorelick, P.B.1
Scuteri, A.2
Black, S.E.3
Decarli, C.4
Greenberg, S.M.5
Iadecola, C.6
Launer, L.J.7
Laurent, S.8
Lopez, O.L.9
Nyenhuis, D.10
Petersen, R.C.11
Schneider, J.A.12
Tzourio, C.13
Arnett, D.K.14
Bennett, D.A.15
Chui, H.C.16
Higashida, R.T.17
Lindquist, R.18
Nilsson, P.M.19
Roman, G.C.20
Sellke, F.W.21
Seshadri, S.22
more..
-
6
-
-
33646779226
-
Modulatory influences on ageing of the vasculature in healthy humans
-
DOI 10.1016/j.exger.2006.01.001, PII S0531556506000234
-
D.R. Seals, K.L. Moreau, P.E. Gates, and I. Eskurza Modulatory influences on ageing of the vasculature in healthy humans Exp. Gerontol. 41 2006 501 507 (Pubitemid 43765901)
-
(2006)
Experimental Gerontology
, vol.41
, Issue.5
, pp. 501-507
-
-
Seals, D.R.1
Moreau, K.L.2
Gates, P.E.3
Eskurza, I.4
-
7
-
-
33846670534
-
Ageing of the conduit arteries
-
DOI 10.1002/path.2101
-
S.E. Greenwald Ageing of the conduit arteries J. Pathol. 211 2007 157 172 (Pubitemid 46195514)
-
(2007)
Journal of Pathology
, vol.211
, Issue.2
, pp. 157-172
-
-
Greenwald, S.E.1
-
8
-
-
0032916924
-
Increased expression of matrix metalloproteinase-2 in the thickened intima of aged rats
-
Z. Li, J. Froehlich, Z.S. Galis, and E.G. Lakatta Increased expression of matrix metalloproteinase-2 in the thickened intima of aged rats Hypertension 33 1999 116 123 (Pubitemid 29061851)
-
(1999)
Hypertension
, vol.33
, Issue.1
, pp. 116-123
-
-
Li, Z.1
Froehlich, J.2
Galis, Z.S.3
Lakatta, E.G.4
-
9
-
-
0038119606
-
Aging increases aortic MMP-2 activity and angiotensin II in nonhuman primates
-
DOI 10.1161/01.HYP.0000073843.56046.45
-
M. Wang, G. Takagi, K. Asai, R.G. Resuello, F.F. Natividad, D.E. Vatner, S.F. Vatner, and E.G. Lakatta Aging increases aortic MMP-2 activity and angiotensin II in nonhuman primates Hypertension 41 2003 1308 1316 (Pubitemid 36706082)
-
(2003)
Hypertension
, vol.41
, Issue.6
, pp. 1308-1316
-
-
Wang, M.1
Takagi, G.2
Asai, K.3
Resuello, R.G.4
Natividad, F.F.5
Vatner, D.E.6
Vatner, S.F.7
Lakatta, E.G.8
-
10
-
-
0036235417
-
Altered regulation of matrix metalloproteinase-2 in aortic remodeling during aging
-
DOI 10.1161/01.HYP.0000014506.13322.66
-
M. Wang, and E.G. Lakatta Altered regulation of matrix metalloproteinase-2 in aortic remodeling during aging Hypertension 39 2002 865 873 (Pubitemid 34437541)
-
(2002)
Hypertension
, vol.39
, Issue.4
, pp. 865-873
-
-
Wang, M.1
Lakatta, E.G.2
-
11
-
-
44849099266
-
Increased matrix metalloproteinase 2 activity in the human internal mammary artery is associated with ageing, hypertension, diabetes and kidney dysfunction
-
DOI 10.1159/000119755
-
A.W. Chung, A.D. Booth, C. Rose, C.R. Thompson, A. Levin, and C. van Breemen Increased matrix metalloproteinase 2 activity in the human internal mammary artery is associated with ageing, hypertension, diabetes and kidney dysfunction J. Vasc. Res. 45 2008 357 362 (Pubitemid 351793739)
-
(2008)
Journal of Vascular Research
, vol.45
, Issue.4
, pp. 357-362
-
-
Chung, A.W.1
Booth, A.D.2
Rose, C.3
Thompson, C.R.4
Levin, A.5
Van Breemen, C.6
-
12
-
-
68549124902
-
COL4A1 is associated with arterial stiffness by genome-wide association scan
-
K.V. Tarasov, S. Sanna, A. Scuteri, J.B. Strait, M. Orru, A. Parsa, P.I. Lin, A. Maschio, S. Lai, M.G. Piras, M. Masala, T. Tanaka, W. Post, J.R. O'Connell, D. Schlessinger, A. Cao, R. Nagaraja, B.D. Mitchell, G.R. Abecasis, A.R. Shuldiner, M. Uda, E.G. Lakatta, and S.S. Najjar COL4A1 is associated with arterial stiffness by genome-wide association scan Circ. Cardiovasc. Genet 2 2009 151 158
-
(2009)
Circ. Cardiovasc. Genet
, vol.2
, pp. 151-158
-
-
Tarasov, K.V.1
Sanna, S.2
Scuteri, A.3
Strait, J.B.4
Orru, M.5
Parsa, A.6
Lin, P.I.7
Maschio, A.8
Lai, S.9
Piras, M.G.10
Masala, M.11
Tanaka, T.12
Post, W.13
O'Connell, J.R.14
Schlessinger, D.15
Cao, A.16
Nagaraja, R.17
Mitchell, B.D.18
Abecasis, G.R.19
Shuldiner, A.R.20
Uda, M.21
Lakatta, E.G.22
Najjar, S.S.23
more..
-
13
-
-
33750336400
-
Collagen type-I degradation is related to arterial stiffness in hypertensive and normotensive subjects
-
DOI 10.1038/sj.jhh.1002015, PII 1002015
-
M. McNulty, A. Mahmud, P. Spiers, and J. Feely Collagen type-I degradation is related to arterial stiffness in hypertensive and normotensive subjects J. Hum. Hypertens. 20 2006 867 873 (Pubitemid 44614069)
-
(2006)
Journal of Human Hypertension
, vol.20
, Issue.11
, pp. 867-873
-
-
McNulty, M.1
Mahmud, A.2
Spiers, P.3
Feely, J.4
-
14
-
-
44349182201
-
Endothelial function and arterial stiffness in normotensive normoglycemic first-degree relatives of diabetic patients are independent of the metabolic syndrome
-
DOI 10.1016/j.numecd.2007.03.008, PII S0939475307000798
-
A. Scuteri, M. Tesauro, S. Rizza, M. Iantorno, M. Federici, D. Lauro, U. Campia, M. Turriziani, A. Fusco, G. Cocciolillo, and R. Lauro Endothelial function and arterial stiffness in normotensive normoglycemic first-degree relatives of diabetic patients are independent of the metabolic syndrome Nutr. Metab. Cardiovasc. Dis. 18 2008 349 356 (Pubitemid 351749803)
-
(2008)
Nutrition, Metabolism and Cardiovascular Diseases
, vol.18
, Issue.5
, pp. 349-356
-
-
Scuteri, A.1
Tesauro, M.2
Rizza, S.3
Iantorno, M.4
Federici, M.5
Lauro, D.6
Campia, U.7
Turriziani, M.8
Fusco, A.9
Cocciolillo, G.10
Lauro, R.11
-
15
-
-
66249112184
-
Endothelial dysfunction in aged humans is related with oxidative stress and vascular inflammation
-
L. Rodriguez-Mañas, M. El-Assar, S. Vallejo, P. Lopez-Doriga, J. Solis, R. Petidier, M. Montes, J. Nevado, M. Castro, C. Gomez-Guerrero, C. Peiro, and C.F. Sanchez-Ferrer Endothelial dysfunction in aged humans is related with oxidative stress and vascular inflammation Aging Cell 8 2009 226 238
-
(2009)
Aging Cell
, vol.8
, pp. 226-238
-
-
Rodriguez-Mañas, L.1
El-Assar, M.2
Vallejo, S.3
Lopez-Doriga, P.4
Solis, J.5
Petidier, R.6
Montes, M.7
Nevado, J.8
Castro, M.9
Gomez-Guerrero, C.10
Peiro, C.11
Sanchez-Ferrer, C.F.12
-
16
-
-
68549109651
-
Large and small artery cross-talk and recent morbidity-mortality trials in hypertension
-
S. Laurent, M. Briet, and P. Boutouyrie Large and small artery cross-talk and recent morbidity-mortality trials in hypertension Hypertension 54 2009 388 392
-
(2009)
Hypertension
, vol.54
, pp. 388-392
-
-
Laurent, S.1
Briet, M.2
Boutouyrie, P.3
-
17
-
-
79960594573
-
Microvascular brain damage with aging and hypertension: Pathophysiological consideration and clinical implications
-
A. Scuteri, P.M. Nilsson, C. Tzourio, J. Redon, and S. Laurent Microvascular brain damage with aging and hypertension: pathophysiological consideration and clinical implications J. Hypertens. 29 2011 1469 1477
-
(2011)
J. Hypertens.
, vol.29
, pp. 1469-1477
-
-
Scuteri, A.1
Nilsson, P.M.2
Tzourio, C.3
Redon, J.4
Laurent, S.5
-
20
-
-
84855836122
-
Physical exercise attenuates age-associated reduction in endothelium-reparative capacity of endothelial progenitor cells by increasing CXCR4/JAK-2 signaling in healthy men
-
W.H. Xia, J. Li, C. Su, Z. Yang, L. Chen, F. Wu, Y.Y. Zhang, B.B. Yu, Y.X. Qiu, S.M. Wang, and J. Tao Physical exercise attenuates age-associated reduction in endothelium-reparative capacity of endothelial progenitor cells by increasing CXCR4/JAK-2 signaling in healthy men Aging Cell 11 2012 111 119
-
(2012)
Aging Cell
, vol.11
, pp. 111-119
-
-
Xia, W.H.1
Li, J.2
Su, C.3
Yang, Z.4
Chen, L.5
Wu, F.6
Zhang, Y.Y.7
Yu, B.B.8
Qiu, Y.X.9
Wang, S.M.10
Tao, J.11
-
21
-
-
33745254210
-
Circulating endothelial progenitor cell deficiency contributes to impaired arterial elasticity in persons of advancing age
-
DOI 10.1038/sj.jhh.1001996, PII 1001996
-
J. Tao, Y. Wang, Z. Yang, C. Tu, M.G. Xu, and J.M. Wang Circulating endothelial progenitor cell deficiency contributes to impaired arterial elasticity in persons of advancing age J. Hum. Hypertens. 20 2006 490 495 (Pubitemid 43923118)
-
(2006)
Journal of Human Hypertension
, vol.20
, Issue.7
, pp. 490-495
-
-
Tao, J.1
Wang, Y.2
Yang, Z.3
Tu, C.4
Xu, M.-G.5
Wang, J.-M.6
-
22
-
-
33847039083
-
Age-dependent impairment of endothelial progenitor cells is corrected by growth-hormone-mediated increase of insulin-like growth-factor-1
-
T. Thum, S. Hoeber, S. Froese, I. Klink, D.O. Stichtenoth, P. Galuppo, M. Jakob, D. Tsikas, S.D. Anker, P.A. Poole-Wilson, J. Borlak, G. Ertl, and J. Bauersachs Age-dependent impairment of endothelial progenitor cells is corrected by growth-hormone-mediated increase of insulin-like growth-factor-1 Circ. Res. 100 2007 434 443
-
(2007)
Circ. Res.
, vol.100
, pp. 434-443
-
-
Thum, T.1
Hoeber, S.2
Froese, S.3
Klink, I.4
Stichtenoth, D.O.5
Galuppo, P.6
Jakob, M.7
Tsikas, D.8
Anker, S.D.9
Poole-Wilson, P.A.10
Borlak, J.11
Ertl, G.12
Bauersachs, J.13
-
23
-
-
18144377085
-
Impaired progenitor cell activity in age-related endothelial dysfunction
-
DOI 10.1016/j.jacc.2004.12.074
-
C. Heiss, S. Keymel, U. Niesler, J. Ziemann, M. Kelm, and C. Kalka Impaired progenitor cell activity in age-related endothelial dysfunction J. Am. Coll. Cardiol. 45 2005 1441 1448 (Pubitemid 40615616)
-
(2005)
Journal of the American College of Cardiology
, vol.45
, Issue.9
, pp. 1441-1448
-
-
Heiss, C.1
Keymel, S.2
Niesler, U.3
Ziemann, J.4
Kelm, M.5
Kalka, C.6
-
24
-
-
77955920784
-
Endothelial dysfunction and vascular disease in later life
-
A. Virdis, L. Ghiadoni, C. Giannarelli, and S. Taddei Endothelial dysfunction and vascular disease in later life Maturitas 67 2010 20 24
-
(2010)
Maturitas
, vol.67
, pp. 20-24
-
-
Virdis, A.1
Ghiadoni, L.2
Giannarelli, C.3
Taddei, S.4
-
25
-
-
84885680836
-
Age-related changes in endothelial function and blood flow regulations
-
Toda, N. Age-related changes in endothelial function and blood flow regulation. Pharmacol. Ther.; 2011.
-
(2011)
Pharmacol. Ther.
-
-
Toda, N.1
-
26
-
-
0038171187
-
Age-related endothelial dysfunction: Potential implications for pharmacotherapy
-
DOI 10.2165/00002512-200320070-00005
-
R.L. Matz, and R. Andriantsitohaina Age-related endothelial dysfunction: potential implications for pharmacotherapy Drugs Aging 20 2003 527 550 (Pubitemid 36688138)
-
(2003)
Drugs and Aging
, vol.20
, Issue.7
, pp. 527-550
-
-
Matz, R.L.1
Andriantsitohaina, R.2
-
27
-
-
0037422592
-
Arterial and cardiac aging: Major shareholders in cardiovascular disease enterprises: Part I: Aging arteries: A "set up" for vascular disease
-
DOI 10.1161/01.CIR.0000048892.83521.58
-
E.G. Lakatta, and D. Levy Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a "set up" for vascular disease Circulation 107 2003 139 146 (Pubitemid 36070946)
-
(2003)
Circulation
, vol.107
, Issue.1
, pp. 139-146
-
-
Lakatta, E.G.1
Levy, D.2
-
29
-
-
84864956001
-
Age-related differences in the effects of alpha and gamma peroxisome proliferator-activated receptor subtype agonists on endothelial vasodilation in human microvessels
-
J. Angulo, S. Vallejo, M. El Assar, J. Garcia-Septiem, C.F. Sanchez-Ferrer, and L. Rodriguez-Manas Age-related differences in the effects of alpha and gamma peroxisome proliferator-activated receptor subtype agonists on endothelial vasodilation in human microvessels Exp. Gerontol 47 2012 734 740
-
(2012)
Exp. Gerontol
, vol.47
, pp. 734-740
-
-
Angulo, J.1
Vallejo, S.2
El Assar, M.3
Garcia-Septiem, J.4
Sanchez-Ferrer, C.F.5
Rodriguez-Manas, L.6
-
30
-
-
0027132065
-
Endothelium-dependent hyperpolarization caused by bradykinin in human coronary arteries
-
M. Nakashima, J.V. Mombouli, A.A. Taylor, and P.M. Vanhoutte Endothelium-dependent hyperpolarization caused by bradykinin in human coronary arteries J. Clin. Invest. 92 1993 2867 2871 (Pubitemid 24006555)
-
(1993)
Journal of Clinical Investigation
, vol.92
, Issue.6
, pp. 2867-2871
-
-
Nakashima, M.1
Mombouli, J.-V.2
Taylor, A.A.3
Vanhoutte, P.M.4
-
31
-
-
0029763530
-
Effect of pregnancy on mechanisms of relaxation in human omental microvessels
-
I.F. Pascoal, and J.G. Umans Effect of pregnancy on mechanisms of relaxation in human omental microvessels Hypertension 28 1996 183 187 (Pubitemid 26322787)
-
(1996)
Hypertension
, vol.28
, Issue.2
, pp. 183-187
-
-
Pascoal, I.F.1
Umans, J.G.2
-
32
-
-
38849085948
-
Differential effects of glucose on agonist-induced relaxations in human mesenteric and subcutaneous arteries
-
DOI 10.1038/sj.bjp.0707592, PII 0707592
-
A. MacKenzie, E.J. Cooper, and F.J. Dowell Differential effects of glucose on agonist-induced relaxations in human mesenteric and subcutaneous arteries Br. J. Pharmacol. 153 2008 480 487 (Pubitemid 351199020)
-
(2008)
British Journal of Pharmacology
, vol.153
, Issue.3
, pp. 480-487
-
-
MacKenzie, A.1
Cooper, E.J.2
Dowell, F.J.3
-
33
-
-
0038340085
-
Calcium dobesilate potentiates endothelium-derived hyperpolarizing factor-mediated relaxation of human penile resistance arteries
-
DOI 10.1038/sj.bjp.0705293
-
J. Angulo, P. Cuevas, A. Fernandez, S. Gabancho, and S. Videla Saenz de Tejada, I. Calcium dobesilate potentiates endothelium-derived hyperpolarizing factor-mediated relaxation of human penile resistance arteries Br. J. Pharmacol. 139 2003 854 862 (Pubitemid 36819613)
-
(2003)
British Journal of Pharmacology
, vol.139
, Issue.4
, pp. 854-862
-
-
Angulo, J.1
Cuevas, P.2
Fernandez, A.3
Gabancho, S.4
Videla, S.5
Saenz De Tejada, I.6
-
34
-
-
30944434869
-
Loss of nitric oxide and endothelial-derived hyperpolarizing factor-mediated responses in aging
-
DOI 10.1111/j.1523-1755.2005.00671.x, PII 4494858
-
D.A. Long, M.A. Newaz, S.S. Prabhakar, K.L. Price, L.D. Truong, L. Feng, W. Mu, A.O. Oyekan, and R.J. Johnson Loss of nitric oxide and endothelial-derived hyperpolarizing factor-mediated responses in aging Kidney Int. 68 2005 2154 2163 (Pubitemid 43117789)
-
(2005)
Kidney International
, vol.68
, Issue.5
, pp. 2154-2163
-
-
Long, D.A.1
Newaz, M.A.2
Prabhakar, S.S.3
Price, K.L.4
Truong, L.D.5
Feng, L.6
Mu, W.7
Oyekan, A.O.8
Johnson, R.J.9
-
35
-
-
33646564988
-
ROS-sensitive cytochrome P450 activity maintains endothelial dilatation in ageing but is transitory in dyslipidaemic mice
-
S. Krummen, A. Drouin, M.E. Gendron, J.R. Falck, and E. Thorin ROS-sensitive cytochrome P450 activity maintains endothelial dilatation in ageing but is transitory in dyslipidaemic mice Br. J. Pharmacol. 147 2006 897 904
-
(2006)
Br. J. Pharmacol.
, vol.147
, pp. 897-904
-
-
Krummen, S.1
Drouin, A.2
Gendron, M.E.3
Falck, J.R.4
Thorin, E.5
-
36
-
-
84880271033
-
Endothelium-dependent hyperpolarization-related relaxations diminish with age in murine saphenous arteries of both sexes
-
Chennupati, R.; Lamers, W. H.; Koehler, S. E.; Mey, J. G. Endothelium-dependent hyperpolarization-related relaxations diminish with age in murine saphenous arteries of both sexes. Br. J. Pharmacol; 2013.
-
(2013)
Br. J. Pharmacol
-
-
Chennupati, R.1
Lamers W., .H.2
Koehler S., .E.3
Mey J., .G.4
-
37
-
-
36649019329
-
Endothelium-derived hyperpolarizing factor as an in vivo back-up mechanism in the cutaneous microcirculation in old mice
-
DOI 10.1113/jphysiol.2007.143750
-
M.L. Gaubert, D. Sigaudo-Roussel, M. Tartas, G. Berrut, J.L. Saumet, and B. Fromy Endothelium-derived hyperpolarizing factor as an in vivo back-up mechanism in the cutaneous microcirculation in old mice J. Physiol. 585 2007 617 626 (Pubitemid 350193929)
-
(2007)
Journal of Physiology
, vol.585
, Issue.2
, pp. 617-626
-
-
Gaubert, M.L.1
Sigaudo-Roussel, D.2
Tartas, M.3
Berrut, G.4
Saumet, J.L.5
Fromy, B.6
-
38
-
-
0031467884
-
Importance of endothelium-derived hyperpolarizing factor in human arteries
-
L. Urakami-Harasawa, H. Shimokawa, M. Nakashima, K. Egashira, and A. Takeshita Importance of endothelium-derived hyperpolarizing factor in human arteries J. Clin. Invest. 100 1997 2793 2799 (Pubitemid 28007548)
-
(1997)
Journal of Clinical Investigation
, vol.100
, Issue.11
, pp. 2793-2799
-
-
Urakami-Harasawa, L.1
Shimokawa, H.2
Nakashima, M.3
Egashira, K.4
Takeshita, A.5
-
39
-
-
84857611520
-
Grape-derived polyphenols improve aging-related endothelial dysfunction in rat mesenteric artery: Role of oxidative stress and the angiotensin system
-
N. Idris Khodja, T. Chataigneau, C. Auger, and V.B. Schini-Kerth Grape-derived polyphenols improve aging-related endothelial dysfunction in rat mesenteric artery: role of oxidative stress and the angiotensin system PLoS One 7 2012 e32039
-
(2012)
PLoS One
, vol.7
, pp. 32039
-
-
Idris Khodja, N.1
Chataigneau, T.2
Auger, C.3
Schini-Kerth, V.B.4
-
40
-
-
4944267105
-
Changes in endothelium-derived hyperpolarizing factor in hypertension and ageing: Response to chronic treatment with renin-angiotensin system inhibitors
-
DOI 10.1111/j.1440-1681.2004.04054.x
-
K. Goto, K. Fujii, Y. Kansui, and M. Iida Changes in endothelium-derived hyperpolarizing factor in hypertension and ageing: response to chronic treatment with renin-angiotensin system inhibitors Clin. Exp. Pharmacol. Physiol. 31 2004 650 655 (Pubitemid 39329769)
-
(2004)
Clinical and Experimental Pharmacology and Physiology
, vol.31
, Issue.9
, pp. 650-655
-
-
Goto, K.1
Fujii, K.2
Kansui, Y.3
Iida, M.4
-
42
-
-
77952506392
-
Exercise training attenuates ageing-induced BKCa channel downregulation in rat coronary arteries
-
S. Albarwani, S. Al-Siyabi, H. Baomar, and M.O. Hassan Exercise training attenuates ageing-induced BKCa channel downregulation in rat coronary arteries Exp. Physiol. 95 2010 746 755
-
(2010)
Exp. Physiol.
, vol.95
, pp. 746-755
-
-
Albarwani, S.1
Al-Siyabi, S.2
Baomar, H.3
Hassan, M.O.4
-
43
-
-
84868271246
-
Aging-shifted prostaglandin profile in endothelium as a factor in cardiovascular disorders
-
H. Qian, N. Luo, and Y. Chi Aging-shifted prostaglandin profile in endothelium as a factor in cardiovascular disorders J. Aging Res 2012 2012 121390
-
(2012)
J. Aging Res
, vol.2012
, pp. 121390
-
-
Qian, H.1
Luo, N.2
Chi, Y.3
-
44
-
-
33846979103
-
Ageing reduces nitric-oxide- and prostaglandin-mediated vasodilatation in exercising humans
-
W.G. Schrage, J.H. Eisenach, and M.J. Joyner Ageing reduces nitric-oxide- and prostaglandin-mediated vasodilatation in exercising humans J. Physiol. 579 2007 227 236
-
(2007)
J. Physiol.
, vol.579
, pp. 227-236
-
-
Schrage, W.G.1
Eisenach, J.H.2
Joyner, M.J.3
-
45
-
-
67049134326
-
Aging is associated with reduced prostacyclin-mediated dilation in the human forearm
-
W.T. Nicholson, B. Vaa, C. Hesse, J.H. Eisenach, and M.J. Joyner Aging is associated with reduced prostacyclin-mediated dilation in the human forearm Hypertension 53 2009 973 978
-
(2009)
Hypertension
, vol.53
, pp. 973-978
-
-
Nicholson, W.T.1
Vaa, B.2
Hesse, C.3
Eisenach, J.H.4
Joyner, M.J.5
-
46
-
-
0031020629
-
Hypertension causes premature aging of endothelial function in humans
-
S. Taddei, A. Virdis, P. Mattei, L. Ghiadoni, C.B. Fasolo, I. Sudano, and A. Salvetti Hypertension causes premature aging of endothelial function in humans Hypertension 29 1997 736 743 (Pubitemid 27097978)
-
(1997)
Hypertension
, vol.29
, Issue.3
, pp. 736-743
-
-
Taddei, S.1
Virdis, A.2
Mattei, P.3
Ghiadoni, L.4
Fasolo, C.B.5
Sudano, I.6
Salvetti, A.7
-
47
-
-
14844320534
-
Endothelium-dependent contractions in hypertension
-
DOI 10.1038/sj.bjp.0706042
-
P.M. Vanhoutte, M. Feletou, and S. Taddei Endothelium-dependent contractions in hypertension Br. J. Pharmacol. 144 2005 449 458 (Pubitemid 40349452)
-
(2005)
British Journal of Pharmacology
, vol.144
, Issue.4
, pp. 449-458
-
-
Vanhoutte, P.M.1
Feletou, M.2
Taddei, S.3
-
48
-
-
56649094583
-
Endothelium-dependent contractions: When a good guy turns bad!
-
P.M. Vanhoutte, and E.H. Tang Endothelium-dependent contractions: when a good guy turns bad! J. Physiol. 586 2008 5295 5304
-
(2008)
J. Physiol.
, vol.586
, pp. 5295-5304
-
-
Vanhoutte, P.M.1
Tang, E.H.2
-
49
-
-
0035224729
-
Cyclo-oxygenase-1 and -2 contribution to endothelial dysfunction in ageing
-
C. Heymes, A. Habib, D. Yang, E. Mathieu, F. Marotte, J. Samuel, and C.M. Boulanger Cyclo-oxygenase-1 and -2 contribution to endothelial dysfunction in ageing Br. J. Pharmacol. 131 2000 804 810
-
(2000)
Br. J. Pharmacol.
, vol.131
, pp. 804-810
-
-
Heymes, C.1
Habib, A.2
Yang, D.3
Mathieu, E.4
Marotte, F.5
Samuel, J.6
Boulanger, C.M.7
-
50
-
-
28944445413
-
Improvement of age-related endothelial dysfunction by simvastatin: Effect on NO and COX pathways
-
DOI 10.1038/sj.bjp.0706420
-
(de) M.A. Sotomayor, C. Perez-Guerrero, M.D. Herrrera, L. Jimenez, R. Marin, E. Marhuenda, and R. Andriantsitohaina Improvement of age-related endothelial dysfunction by simvastatin: effect on NO and COX pathways Br. J. Pharmacol. 146 2005 1130 1138 (Pubitemid 41785324)
-
(2005)
British Journal of Pharmacology
, vol.146
, Issue.8
, pp. 1130-1138
-
-
De Sotomayor, M.A.1
Perez-Guerrero, C.2
Herrrera, Ma.D.3
Jimenez, L.4
Marin, R.5
Marhuenda, E.6
Andriantsitohaina, R.7
-
51
-
-
38749089857
-
Two isoforms of cyclooxygenase contribute to augmented endothelium- dependent contractions in femoral arteries of 1-year-old rats
-
DOI 10.1111/j.1745-7254.2008.00749.x
-
Y. Shi, R.Y. Man, and P.M. Vanhoutte Two isoforms of cyclooxygenase contribute to augmented endothelium-dependent contractions in femoral arteries of 1-year-old rats Acta Pharmacol. Sin 29 2008 185 192 (Pubitemid 351178432)
-
(2008)
Acta Pharmacologica Sinica
, vol.29
, Issue.2
, pp. 185-192
-
-
Shi, Y.1
Man, R.Y.2
Vanhoutte, P.M.3
-
52
-
-
33745934653
-
Oxidative alterations of cyclooxygenase during atherogenesis
-
DOI 10.1016/j.prostaglandins.2006.05.009, PII S1098882306000669
-
R.K. Upmacis, R.S. Deeb, and D.P. Hajjar Oxidative alterations of cyclooxygenase during atherogenesis Prostaglandins Other Lipid Mediat. 80 2006 1 14 (Pubitemid 44056286)
-
(2006)
Prostaglandins and Other Lipid Mediators
, vol.80
, Issue.1-2
, pp. 1-14
-
-
Upmacis, R.K.1
Deeb, R.S.2
Hajjar, D.P.3
-
53
-
-
29344465714
-
Medicine: Inducible nitric oxide synthase binds, S-nitrosylates, and activates cyclooxygenase-2
-
DOI 10.1126/science.1119407
-
S.F. Kim, D.A. Huri, and S.H. Snyder Inducible nitric oxide synthase binds, S-nitrosylates, and activates cyclooxygenase-2 Science 310 2005 1966 1970 (Pubitemid 43005992)
-
(2005)
Science
, vol.310
, Issue.5756
, pp. 1966-1970
-
-
Kim, S.F.1
Huri, D.A.2
Snyder, S.H.3
-
54
-
-
74549142287
-
The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha
-
L. Zhong, A. D'Urso, D. Toiber, C. Sebastian, R.E. Henry, D.D. Vadysirisack, A. Guimaraes, B. Marinelli, J.D. Wikstrom, T. Nir, C.B. Clish, B. Vaitheesvaran, O. Iliopoulos, I. Kurland, Y. Dor, R. Weissleder, O.S. Shirihai, L.W. Ellisen, J.M. Espinosa, and R. Mostoslavsky The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha Cell 140 2010 280 293
-
(2010)
Cell
, vol.140
, pp. 280-293
-
-
Zhong, L.1
D'Urso, A.2
Toiber, D.3
Sebastian, C.4
Henry, R.E.5
Vadysirisack, D.D.6
Guimaraes, A.7
Marinelli, B.8
Wikstrom, J.D.9
Nir, T.10
Clish, C.B.11
Vaitheesvaran, B.12
Iliopoulos, O.13
Kurland, I.14
Dor, Y.15
Weissleder, R.16
Shirihai, O.S.17
Ellisen, L.W.18
Espinosa, J.M.19
Mostoslavsky, R.20
more..
-
55
-
-
67649877883
-
Nitric oxide synthases and cardiovascular diseases: Insights from genetically modified mice
-
M. Tsutsui, H. Shimokawa, Y. Otsuji, Y. Ueta, Y. Sasaguri, and N. Yanagihara Nitric oxide synthases and cardiovascular diseases: insights from genetically modified mice Circ. J. 73 2009 986 993
-
(2009)
Circ. J.
, vol.73
, pp. 986-993
-
-
Tsutsui, M.1
Shimokawa, H.2
Otsuji, Y.3
Ueta, Y.4
Sasaguri, Y.5
Yanagihara, N.6
-
56
-
-
0037499422
-
Aged endothelial nitric oxide synthase knockout mice exhibit higher mortality concomitant with impaired open-field habituation and alterations in forebrain neurotransmitter levels
-
DOI 10.1034/j.1601-183X.2002.10402.x
-
E. Dere, M.A. De Souza Silva, B. Topic, C. Fiorillo, J.S. Li, A.G. Sadile, C. Frisch, and J.P. Huston Aged endothelial nitric oxide synthase knockout mice exhibit higher mortality concomitant with impaired open-field habituation and alterations in forebrain neurotransmitter levels Genes Brain Behav. 1 2002 204 213 (Pubitemid 36717666)
-
(2002)
Genes, Brain and Behavior
, vol.1
, Issue.4
, pp. 204-213
-
-
Dere, E.1
De Souza Silva, M.A.2
Topic, B.3
Fiorillo, C.4
Li, J.-S.5
Sadile, A.G.6
Frisch, C.7
Huston, J.P.8
-
57
-
-
26844558334
-
Cell biology: Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS
-
DOI 10.1126/science.1117728
-
E. Nisoli, C. Tonello, A. Cardile, V. Cozzi, R. Bracale, L. Tedesco, S. Falcone, A. Valerio, O. Cantoni, E. Clementi, S. Moncada, and M.O. Carruba Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS Science 310 2005 314 317 (Pubitemid 41457197)
-
(2005)
Science
, vol.310
, Issue.5746
, pp. 314-317
-
-
Nisoli, E.1
Tonello, C.2
Cardile, A.3
Cozzi, V.4
Bracale, R.5
Tedesco, L.6
Falcone, S.7
Valerio, A.8
Cantoni, O.9
Clementi, E.10
Moncada, S.11
Carruba, M.O.12
-
58
-
-
2542467787
-
Reduced release of nitric oxide to shear stress in mesenteric arteries of aged rats
-
D. Sun, A. Huang, E.H. Yan, Z. Wu, C. Yan, P.M. Kaminski, T.D. Oury, M.S. Wolin, and G. Kaley Reduced release of nitric oxide to shear stress in mesenteric arteries of aged rats Am. J. Physiol. Heart Circ. Physol 286 2004 H2249 H2256
-
(2004)
Am. J. Physiol. Heart Circ. Physol
, vol.286
-
-
Sun, D.1
Huang, A.2
Yan, E.H.3
Wu, Z.4
Yan, C.5
Kaminski, P.M.6
Oury, T.D.7
Wolin, M.S.8
Kaley, G.9
-
59
-
-
20644454629
-
Circulating and cellular markers of endothelial dysfunction with aging in rats
-
M. Challah, S. Nadaud, M. Philippe, T. Battle, F. Soubrier, B. Corman, and J.B. Michel Circulating and cellular markers of endothelial dysfunction with aging in rats Am. J. Physiol. 273 1997 H1941 H1948
-
(1997)
Am. J. Physiol.
, vol.273
-
-
Challah, M.1
Nadaud, S.2
Philippe, M.3
Battle, T.4
Soubrier, F.5
Corman, B.6
Michel, J.B.7
-
60
-
-
0032504749
-
Expression of constitutive and inducible nitric oxide synthases in the vascular wall of young and aging rats
-
M.R. Cernadas, L. Sanchez de Miguel, M. Garcia-Duran, F. Gonzalez-Fernandez, I. Millas, M. Monton, J. Rodrigo, L. Rico, P. Fernandez, T. de Frutos, J.A. Rodriguez-Feo, J. Guerra, C. Caramelo, S. Casado, and F. Lopez Expression of constitutive and inducible nitric oxide synthases in the vascular wall of young and aging rats Cir. Res 83 1998 279 286 (Pubitemid 28371317)
-
(1998)
Circulation Research
, vol.83
, Issue.3
, pp. 279-286
-
-
Cernadas, M.R.1
De Miguel, L.S.2
Garcia-Duran, M.3
Gonzalez-Fernandez, F.4
Millas, I.5
Monton, M.6
Rodrigo, J.7
Rico, L.8
Fernandez, P.9
De Frutos, T.10
Rodriguez-Feo, J.A.11
Guerra, J.12
Caramelo, C.13
Casado, S.14
Lopez-Farre, A.15
-
61
-
-
26044445766
-
Ageing affects nitric oxide synthase, cyclooxygenase and oxidative stress enzymes expression differently in mesenteric resistance arteries
-
DOI 10.1111/j.1474-8673.2005.00344.x
-
A.M. Briones, N. Montoya, J. Giraldo, and E. Vila Ageing affects nitric oxide synthase, cyclooxygenase and oxidative stress enzymes expression differently in mesenteric resistance arteries Auton. Autacoid Pharmacol 25 2005 155 162 (Pubitemid 41406039)
-
(2005)
Autonomic and Autacoid Pharmacology
, vol.25
, Issue.4
, pp. 155-162
-
-
Briones, A.M.1
Montoya, N.2
Giraldo, J.3
Vila, E.4
-
62
-
-
67650073156
-
Vascular endothelial dysfunction with aging: Endothelin-1 and endothelial nitric oxide synthase
-
A.J. Donato, L.B. Gano, I. Eskurza, A.E. Silver, P.E. Gates, K. Jablonski, and D.R. Seals Vascular endothelial dysfunction with aging: endothelin-1 and endothelial nitric oxide synthase Am. J. Physiol. Heart Circ. Physol 297 2009 H425 H432
-
(2009)
Am. J. Physiol. Heart Circ. Physol
, vol.297
-
-
Donato, A.J.1
Gano, L.B.2
Eskurza, I.3
Silver, A.E.4
Gates, P.E.5
Jablonski, K.6
Seals, D.R.7
-
63
-
-
84866346582
-
Differential modulation of nitric oxide synthases in aging: Therapeutic opportunities
-
S.B. Cau, F.S. Carneiro, and R.C. Tostes Differential modulation of nitric oxide synthases in aging: therapeutic opportunities Front. Physiol 3 2012 218
-
(2012)
Front. Physiol
, vol.3
, pp. 218
-
-
Cau, S.B.1
Carneiro, F.S.2
Tostes, R.C.3
-
65
-
-
33845400838
-
Impaired shear stress-induced nitric oxide production through decreased NOS phosphorylation contributes to age-related vascular stiffness
-
DOI 10.1152/japplphysiol.00138.2006
-
K.G. Soucy, S. Ryoo, A. Benjo, H.K. Lim, G. Gupta, J.S. Sohi, J. Elser, M.A. Aon, D. Nyhan, A.A. Shoukas, and D.E. Berkowitz Impaired shear stress-induced nitric oxide production through decreased NOS phosphorylation contributes to age-related vascular stiffness J. Appl. Physiol. 101 2006 1751 1759 (Pubitemid 44904498)
-
(2006)
Journal of Applied Physiology
, vol.101
, Issue.6
, pp. 1751-1759
-
-
Soucy, K.G.1
Ryoo, S.2
Benjo, A.3
Hyun, K.L.4
Gupta, G.5
Sohi, J.S.6
Elser, J.7
Aon, M.A.8
Nyhan, D.9
Shoukas, A.A.10
Berkowitz, D.E.11
-
67
-
-
34250216014
-
Direct evidence of endothelial oxidative stress with aging in humans: Relation to impaired endothelium-dependent dilation and upregulation of nuclear factor-κB
-
DOI 10.1161/01.RES.0000269183.13937.e8
-
A.J. Donato, I. Eskurza, A.E. Silver, A.S. Levy, G.L. Pierce, P.E. Gates, and D.R. Seals Direct evidence of endothelial oxidative stress with aging in humans: relation to impaired endothelium-dependent dilation and upregulation of nuclear factor-kappaB Cir. Res 100 2007 1659 1666 (Pubitemid 46897269)
-
(2007)
Circulation Research
, vol.100
, Issue.11
, pp. 1659-1666
-
-
Donato, A.J.1
Eskurza, I.2
Silver, A.E.3
Levy, A.S.4
Pierce, G.L.5
Gates, P.E.6
Seals, D.R.7
-
68
-
-
1942438660
-
Effect of acute and chronic ascorbic acid on flow-mediated dilatation with sedentary and physically active human ageing
-
DOI 10.1113/jphysiol.2003.057042
-
I. Eskurza, K.D. Monahan, J.A. Robinson, and D.R. Seals Effect of acute and chronic ascorbic acid on flow-mediated dilatation with sedentary and physically active human ageing J. Physiol. 556 2004 315 324 (Pubitemid 38519054)
-
(2004)
Journal of Physiology
, vol.556
, Issue.1
, pp. 315-324
-
-
Eskurza, I.1
Monahan, K.D.2
Robinson, J.A.3
Seals, D.R.4
-
69
-
-
33646402907
-
Tetrahydrobiopterin improves aging-related impairment of endothelium-dependent vasodilation through increase in nitric oxide production
-
Y. Higashi, S. Sasaki, K. Nakagawa, M. Kimura, K. Noma, K. Hara, D. Jitsuiki, C. Goto, T. Oshima, K. Chayama, and M. Yoshizumi Tetrahydrobiopterin improves aging-related impairment of endothelium-dependent vasodilation through increase in nitric oxide production Atherosclerosis 186 2006 390 395
-
(2006)
Atherosclerosis
, vol.186
, pp. 390-395
-
-
Higashi, Y.1
Sasaki, S.2
Nakagawa, K.3
Kimura, M.4
Noma, K.5
Hara, K.6
Jitsuiki, D.7
Goto, C.8
Oshima, T.9
Chayama, K.10
Yoshizumi, M.11
-
70
-
-
33646052273
-
Endothelium, aging, and hypertension
-
S. Taddei, A. Virdis, L. Ghiadoni, D. Versari, and A. Salvetti Endothelium, aging, and hypertension Curr. Hypertens. Rep. 8 2006 84 89
-
(2006)
Curr. Hypertens. Rep.
, vol.8
, pp. 84-89
-
-
Taddei, S.1
Virdis, A.2
Ghiadoni, L.3
Versari, D.4
Salvetti, A.5
-
71
-
-
0016414528
-
Superoxide dismutases
-
I. Fridovich Superoxide dismutases Annu. Rev. Biochem. 44 1975 147 159
-
(1975)
Annu. Rev. Biochem.
, vol.44
, pp. 147-159
-
-
Fridovich, I.1
-
72
-
-
0018776894
-
Hydroperoxide metabolism in mammalian organs
-
B. Chance, H. Sies, and A. Boveris Hydroperoxide metabolism in mammalian organs Physiol. Rev. 59 1979 527 605 (Pubitemid 9236599)
-
(1979)
Physiological Reviews
, vol.59
, Issue.3
, pp. 527-605
-
-
Chance, B.1
Sies, H.2
Boveris, A.3
-
73
-
-
33749986298
-
Free radicals and antioxidants in normal physiological functions and human disease
-
DOI 10.1016/j.biocel.2006.07.001, PII S1357272506002196
-
M. Valko, D. Leibfritz, J. Moncol, M.T. Cronin, M. Mazur, and J. Telser Free radicals and antioxidants in normal physiological functions and human disease Int. J. Biochem. Cell Biol. 39 2007 44 84 (Pubitemid 44566469)
-
(2007)
International Journal of Biochemistry and Cell Biology
, vol.39
, Issue.1
, pp. 44-84
-
-
Valko, M.1
Leibfritz, D.2
Moncol, J.3
Cronin, M.T.D.4
Mazur, M.5
Telser, J.6
-
75
-
-
58849155179
-
Vascular endothelial senescence: From mechanisms to pathophysiology
-
J.D. Erusalimsky Vascular endothelial senescence: from mechanisms to pathophysiology J. Appl. Physiol. 106 2009 326 332
-
(2009)
J. Appl. Physiol.
, vol.106
, pp. 326-332
-
-
Erusalimsky, J.D.1
-
76
-
-
33750944018
-
Endothelial cellular senescence is inhibited by nitric oxide: Implications in atherosclerosis associated with menopause and diabetes
-
DOI 10.1073/pnas.0607873103
-
T. Hayashi, H. Matsui-Hirai, A. Miyazaki-Akita, A. Fukatsu, J. Funami, Q.F. Ding, S. Kamalanathan, Y. Hattori, L.J. Ignarro, and A. Iguchi Endothelial cellular senescence is inhibited by nitric oxide: implications in atherosclerosis associated with menopause and diabetes Proc. Natl. Acad. Sci. USA 103 2006 17018 17023 (Pubitemid 44737370)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.45
, pp. 17018-17023
-
-
Hayashi, T.1
Matsui-Hirai, H.2
Miyazaki-Akita, A.3
Fukatsu, A.4
Funami, J.5
Ding, Q.-F.6
Kamalanathan, S.7
Nation, Y.8
Ignarro, L.J.9
Iguchi, A.10
-
77
-
-
84885680740
-
2 on cell death, reactive oxygen species and glutathione levels in calf pulmonary artery and human umbilical vein endothelial cells
-
2 on cell death, reactive oxygen species and glutathione levels in calf pulmonary artery and human umbilical vein endothelial cells Int. J. Mol. Med 2012
-
(2012)
Int. J. Mol. Med
-
-
Park, W.H.1
-
78
-
-
36048960679
-
Nuclear redox-signaling is essential for apoptosis inhibition in endothelial cells-important role for nuclear thioredoxin-1
-
DOI 10.1161/ATVBAHA.107.149419, PII 0004360520071100000009
-
P. Schroeder, R. Popp, B. Wiegand, J. Altschmied, and J. Haendeler Nuclear redox-signaling is essential for apoptosis inhibition in endothelial cells - important role for nuclear thioredoxin-1 Arterioscler. Thromb. Vasc. Biol. 27 2007 2325 2331 (Pubitemid 350203946)
-
(2007)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.27
, Issue.11
, pp. 2325-2331
-
-
Schroeder, P.1
Popp, R.2
Wiegand, B.3
Altschmied, J.4
Haendeler, J.5
-
79
-
-
80051622409
-
Accelerated vascular aging in CuZnSOD-deficient mice: Impact on EPC function and reparative neovascularization
-
J. Groleau, S. Dussault, J. Turgeon, P. Haddad, and A. Rivard Accelerated vascular aging in CuZnSOD-deficient mice: impact on EPC function and reparative neovascularization PLoS One 6 2011 e23308
-
(2011)
PLoS One
, vol.6
, pp. 23308
-
-
Groleau, J.1
Dussault, S.2
Turgeon, J.3
Haddad, P.4
Rivard, A.5
-
80
-
-
84863090733
-
Protection against vascular aging in Nox2-deficient mice: Impact on endothelial progenitor cells and reparative neovascularization
-
J. Turgeon, P. Haddad, S. Dussault, J. Groleau, F. Maingrette, G. Perez, and A. Rivard Protection against vascular aging in Nox2-deficient mice: impact on endothelial progenitor cells and reparative neovascularization Atherosclerosis 223 2012 122 129
-
(2012)
Atherosclerosis
, vol.223
, pp. 122-129
-
-
Turgeon, J.1
Haddad, P.2
Dussault, S.3
Groleau, J.4
Maingrette, F.5
Perez, G.6
Rivard, A.7
-
81
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
D. Harman Aging: a theory based on free radical and radiation chemistry J. Gerontol. 11 1956 298 300
-
(1956)
J. Gerontol.
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
82
-
-
64049083005
-
Reactive oxygen species and the control of vascular function
-
M.S. Wolin Reactive oxygen species and the control of vascular function Am. J. Physiol. Heart Circ. Physol 296 2009 H539 H549
-
(2009)
Am. J. Physiol. Heart Circ. Physol
, vol.296
-
-
Wolin, M.S.1
-
83
-
-
33846863589
-
Nitric oxide and peroxynitrite in health and disease
-
DOI 10.1152/physrev.00029.2006
-
P. Pacher, J.S. Beckman, and L. Liaudet Nitric oxide and peroxynitrite in health and disease Physiol. Rev. 87 2007 315 424 (Pubitemid 46217686)
-
(2007)
Physiological Reviews
, vol.87
, Issue.1
, pp. 315-424
-
-
Pacher, P.1
Beckman, J.S.2
Liaudet, L.3
-
84
-
-
0037046214
-
Mechanisms of increased vascular superoxide production in human diabetes mellitus: Role of NAD(P)H oxidase and endothelial nitric oxide synthase
-
DOI 10.1161/01.CIR.0000012748.58444.08
-
T.J. Guzik, S. Mussa, D. Gastaldi, J. Sadowski, C. Ratnatunga, R. Pillai, and K.M. Channon Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthase Circulation 105 2002 1656 1662 (Pubitemid 34298608)
-
(2002)
Circulation
, vol.105
, Issue.14
, pp. 1656-1662
-
-
Guzik, T.J.1
Mussa, S.2
Gastaldi, D.3
Sadowski, J.4
Ratnatunga, C.5
Pillai, R.6
Channon, K.M.7
-
85
-
-
0034684652
-
Enhanced peroxynitrite formation is associated with vascular aging
-
B. van der Loo, R. Labugger, J.N. Skepper, M. Bachschmid, J. Kilo, J.M. Powell, M. Palacios-Callender, J.D. Erusalimsky, T. Quaschning, T. Malinski, D. Gygi, V. Ullrich, and T.F. Luscher Enhanced peroxynitrite formation is associated with vascular aging J. Exp. Med. 192 2000 1731 1744
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1731-1744
-
-
Van Der Loo, B.1
Labugger, R.2
Skepper, J.N.3
Bachschmid, M.4
Kilo, J.5
Powell, J.M.6
Palacios-Callender, M.7
Erusalimsky, J.D.8
Quaschning, T.9
Malinski, T.10
Gygi, D.11
Ullrich, V.12
Luscher, T.F.13
-
86
-
-
34547673497
-
Peroxynitrite: Biochemistry, pathophysiology and development of therapeutics
-
DOI 10.1038/nrd2222, PII NRD2222
-
C. Szabo, H. Ischiropoulos, and R. Radi Peroxynitrite: biochemistry, pathophysiology and development of therapeutics Nat. Rev. Drug Discov. 6 2007 662 680 (Pubitemid 47207751)
-
(2007)
Nature Reviews Drug Discovery
, vol.6
, Issue.8
, pp. 662-680
-
-
Szabo, C.1
Ischiropoulos, H.2
Radi, R.3
-
87
-
-
0035097953
-
Superoxide excess in hypertension and aging a common cause of endothelial dysfunction
-
C.A. Hamilton, M.J. Brosnan, M. McIntyre, D. Graham, and A.F. Dominiczak Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction Hypertension 37 2001 529 534 (Pubitemid 32199023)
-
(2001)
Hypertension
, vol.37
, Issue.2
, pp. 529-534
-
-
Hamilton, C.A.1
Brosnan, M.J.2
McIntyre, M.3
Graham, D.4
Dominiczak, A.F.5
-
88
-
-
39049135381
-
Loss of adaptation to oxidative stress as a mechanism for aortic damage in aging rats
-
F. Marmol, J. Sanchez, D. Lopez, N. Martinez, J. Rosello-Catafau, M.T. Mitjavila, and P. Puig-Parellada Loss of adaptation to oxidative stress as a mechanism for aortic damage in aging rats J. Physiol. Biochem. 63 2007 239 247
-
(2007)
J. Physiol. Biochem.
, vol.63
, pp. 239-247
-
-
Marmol, F.1
Sanchez, J.2
Lopez, D.3
Martinez, N.4
Rosello-Catafau, J.5
Mitjavila, M.T.6
Puig-Parellada, P.7
-
89
-
-
79961043903
-
Vascular oxidative stress in aging: A homeostatic failure due to dysregulation of NRF2-mediated antioxidant response
-
Z. Ungvari, L. Bailey-Downs, D. Sosnowska, T. Gautam, P. Koncz, G. Losonczy, P. Ballabh, R. de Cabo, W.E. Sonntag, and A. Csiszar Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of NRF2-mediated antioxidant response Am. J. Physiol. Heart Circ. Physol 301 2011 H363 H372
-
(2011)
Am. J. Physiol. Heart Circ. Physol
, vol.301
-
-
Ungvari, Z.1
Bailey-Downs, L.2
Sosnowska, D.3
Gautam, T.4
Koncz, P.5
Losonczy, G.6
Ballabh, P.7
De Cabo, R.8
Sonntag, W.E.9
Csiszar, A.10
-
90
-
-
0038718728
-
Aging-induced proinflammatory shift in cytokine expression profile in coronary arteries
-
A. Csiszar, Z. Ungvari, A. Koller, J.G. Edwards, and G. Kaley Aging-induced proinflammatory shift in cytokine expression profile in coronary arteries FASEB J 17 2003 1183 1185
-
(2003)
FASEB J
, vol.17
, pp. 1183-1185
-
-
Csiszar, A.1
Ungvari, Z.2
Koller, A.3
Edwards, J.G.4
Kaley, G.5
-
91
-
-
8144229685
-
shc gene protects against age-related endothelial dysfunction
-
DOI 10.1161/01.CIR.0000147731.24444.4D
-
P. Francia, C. delli Gatti, M. Bachschmid, I. Martin-Padura, C. Savoia, E. Migliaccio, P.G. Pelicci, M. Schiavoni, T.F. Luscher, M. Volpe, and F. Cosentino Deletion of p66shc gene protects against age-related endothelial dysfunction Circulation 110 2004 2889 2895 (Pubitemid 39473614)
-
(2004)
Circulation
, vol.110
, Issue.18
, pp. 2889-2895
-
-
Francia, P.1
Delli Gatti, C.2
Bachschmid, M.3
Martin-Padura, I.4
Savoia, C.5
Migliaccio, E.6
Pelicci, P.G.7
Schiavoni, M.8
Luscher, T.F.9
Volpe, M.10
Cosentino, F.11
-
92
-
-
36249022195
-
Vascular superoxide and hydrogen peroxide production and oxidative stress resistance in two closely related rodent species with disparate longevity
-
DOI 10.1111/j.1474-9726.2007.00339.x
-
A. Csiszar, N. Labinskyy, X. Zhao, F. Hu, S. Serpillon, Z. Huang, P. Ballabh, R.J. Levy, T.H. Hintze, M.S. Wolin, S.N. Austad, A. Podlutsky, and Z. Ungvari Vascular superoxide and hydrogen peroxide production and oxidative stress resistance in two closely related rodent species with disparate longevity Aging Cell 6 2007 783 797 (Pubitemid 350131047)
-
(2007)
Aging Cell
, vol.6
, Issue.6
, pp. 783-797
-
-
Csiszar, A.1
Labinskyy, N.2
Zhao, X.3
Hu, F.4
Serpillon, S.5
Huang, Z.6
Ballabh, P.7
Levy, R.J.8
Hintze, T.H.9
Wolin, M.S.10
Austad, S.N.11
Podlutsky, A.12
Ungvari, Z.13
-
93
-
-
58149279843
-
Lipoteichoic acid induces HO-1 expression via the TLR2/MyD88/c-Src/NADPH oxidase pathway and Nrf2 in human tracheal smooth muscle cells
-
I.T. Lee, S.W. Wang, C.W. Lee, C.C. Chang, C.C. Lin, S.F. Luo, and C.M. Yang Lipoteichoic acid induces HO-1 expression via the TLR2/MyD88/c-Src/NADPH oxidase pathway and Nrf2 in human tracheal smooth muscle cells J. Immunol. 181 2008 5098 5110
-
(2008)
J. Immunol.
, vol.181
, pp. 5098-5110
-
-
Lee, I.T.1
Wang, S.W.2
Lee, C.W.3
Chang, C.C.4
Lin, C.C.5
Luo, S.F.6
Yang, C.M.7
-
94
-
-
84858314014
-
Increased expression of Nox1 in neointimal smooth muscle cells promotes activation of matrix metalloproteinase-9
-
S. Xu, A.S. Shriver, D.K. Jagadeesha, A.H. Chamseddine, K. Szocs, N.L. Weintraub, K.K. Griendling, R.C. Bhalla, and F.J. Miller Jr. Increased expression of Nox1 in neointimal smooth muscle cells promotes activation of matrix metalloproteinase-9 J. Vasc. Res. 49 2012 242 248
-
(2012)
J. Vasc. Res.
, vol.49
, pp. 242-248
-
-
Xu, S.1
Shriver, A.S.2
Jagadeesha, D.K.3
Chamseddine, A.H.4
Szocs, K.5
Weintraub, N.L.6
Griendling, K.K.7
Bhalla, R.C.8
Miller, Jr.F.J.9
-
95
-
-
33847029945
-
Phagocytic NADPH oxidase-dependent superoxide production stimulates matrix metalloproteinase-9: Implications for human atherosclerosis
-
G. Zalba, A. Fortuno, J. Orbe, G. San Jose, M.U. Moreno, M. Belzunce, J.A. Rodriguez, O. Beloqui, J.A. Paramo, and J. Diez Phagocytic NADPH oxidase-dependent superoxide production stimulates matrix metalloproteinase-9: implications for human atherosclerosis Arterioscler. Thromb. Vasc. Biol. 27 2007 587 593
-
(2007)
Arterioscler. Thromb. Vasc. Biol.
, vol.27
, pp. 587-593
-
-
Zalba, G.1
Fortuno, A.2
Orbe, J.3
San Jose, G.4
Moreno, M.U.5
Belzunce, M.6
Rodriguez, J.A.7
Beloqui, O.8
Paramo, J.A.9
Diez, J.10
-
96
-
-
79956117923
-
NAD(P)H oxidase-derived reactive oxygen species contribute to age-related impairments of endothelium-dependent dilation in rat soleus feed arteries
-
D.W. Trott, J.W. Seawright, M.J. Luttrell, and C.R. Woodman NAD(P)H oxidase-derived reactive oxygen species contribute to age-related impairments of endothelium-dependent dilation in rat soleus feed arteries J. Appl. Physiol. 110 2011 1171 1180
-
(2011)
J. Appl. Physiol.
, vol.110
, pp. 1171-1180
-
-
Trott, D.W.1
Seawright, J.W.2
Luttrell, M.J.3
Woodman, C.R.4
-
97
-
-
84858333077
-
Superoxide-lowering therapy with TEMPOL reverses arterial dysfunction with aging in mice
-
B.S. Fleenor, D.R. Seals, M.L. Zigler, and A.L. Sindler Superoxide-lowering therapy with TEMPOL reverses arterial dysfunction with aging in mice Aging Cell 11 2012 269 276
-
(2012)
Aging Cell
, vol.11
, pp. 269-276
-
-
Fleenor, B.S.1
Seals, D.R.2
Zigler, M.L.3
Sindler, A.L.4
-
98
-
-
0034634281
-
Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress
-
H. Cai, and D.G. Harrison Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress Cir. Res 87 2000 840 844
-
(2000)
Cir. Res
, vol.87
, pp. 840-844
-
-
Cai, H.1
Harrison, D.G.2
-
100
-
-
0034624994
-
What we know and don't know about L-arginine and NO
-
J. Loscalzo What we know and don't know about L-arginine and NO Circulation 101 2000 2126 2129 (Pubitemid 30253037)
-
(2000)
Circulation
, vol.101
, Issue.18
, pp. 2126-2129
-
-
Loscalzo, J.1
-
101
-
-
60349119717
-
Signalling processes in endothelial ageing in relation to chronic oxidative stress and their potential therapeutic implications in humans
-
B. van der Loo, S. Schildknecht, R. Zee, and M.M. Bachschmid Signalling processes in endothelial ageing in relation to chronic oxidative stress and their potential therapeutic implications in humans Exp. Physiol 94 2009 305 310
-
(2009)
Exp. Physiol
, vol.94
, pp. 305-310
-
-
Van Der Loo, B.1
Schildknecht, S.2
Zee, R.3
Bachschmid, M.M.4
-
103
-
-
0034306267
-
Mitochondria, oxygen free radicals, disease and ageing
-
S. Raha, and B.H. Robinson Mitochondria, oxygen free radicals, disease and ageing Trends Biochem. Sci. 25 2000 502 508
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 502-508
-
-
Raha, S.1
Robinson, B.H.2
-
104
-
-
4444297565
-
Mitochondria: Are they the seat of senescence?
-
DOI 10.1046/j.1474-9728.2003.00075.x
-
I. Fridovich Mitochondria: are they the seat of senescence? Aging Cell 3 2004 13 16 (Pubitemid 40246656)
-
(2004)
Aging Cell
, vol.3
, Issue.1
, pp. 13-16
-
-
Fridovich, I.1
-
105
-
-
41949114990
-
Role of mitochondrial dysfunction in insulin resistance
-
DOI 10.1161/CIRCRESAHA.107.165472, PII 0000301220080229000005
-
J.A. Kim, Y. Wei, and J.R. Sowers Role of mitochondrial dysfunction in insulin resistance Cir. Res 102 2008 401 414 (Pubitemid 351651099)
-
(2008)
Circulation Research
, vol.102
, Issue.4
, pp. 401-414
-
-
Kim, J.-A.1
Wei, Y.2
Sowers, J.R.3
-
106
-
-
44949220235
-
Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats
-
Z. Ungvari, N. Labinskyy, S. Gupte, P.N. Chander, J.G. Edwards, and A. Csiszar Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats Am. J. Physiol. Heart Circ. Physol 294 2008 H2121 H2128
-
(2008)
Am. J. Physiol. Heart Circ. Physol
, vol.294
-
-
Ungvari, Z.1
Labinskyy, N.2
Gupte, S.3
Chander, P.N.4
Edwards, J.G.5
Csiszar, A.6
-
107
-
-
72249107744
-
Mitochondrial-derived hydrogen peroxide inhibits relaxation of bovine coronary arterial smooth muscle to hypoxia through stimulation of ERK MAP kinase
-
Q. Gao, X. Zhao, M. Ahmad, and M.S. Wolin Mitochondrial-derived hydrogen peroxide inhibits relaxation of bovine coronary arterial smooth muscle to hypoxia through stimulation of ERK MAP kinase Am. J. Physiol. Heart Circ. Physol 297 2009 H2262 H2269
-
(2009)
Am. J. Physiol. Heart Circ. Physol
, vol.297
-
-
Gao, Q.1
Zhao, X.2
Ahmad, M.3
Wolin, M.S.4
-
108
-
-
54149096363
-
Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction
-
P. Wenzel, S. Schuhmacher, J. Kienhofer, J. Muller, M. Hortmann, M. Oelze, E. Schulz, N. Treiber, T. Kawamoto, K. Scharffetter-Kochanek, T. Munzel, A. Burkle, M.M. Bachschmid, and A. Daiber Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction Cardiovasc. Res. 80 2008 280 289
-
(2008)
Cardiovasc. Res.
, vol.80
, pp. 280-289
-
-
Wenzel, P.1
Schuhmacher, S.2
Kienhofer, J.3
Muller, J.4
Hortmann, M.5
Oelze, M.6
Schulz, E.7
Treiber, N.8
Kawamoto, T.9
Scharffetter-Kochanek, K.10
Munzel, T.11
Burkle, A.12
Bachschmid, M.M.13
Daiber, A.14
-
109
-
-
84857653603
-
Mitochondrial oxidative stress in aortic stiffening with age: The role of smooth muscle cell function
-
R.H. Zhou, A.E. Vendrov, I. Tchivilev, X.L. Niu, K.C. Molnar, M. Rojas, J.D. Carter, H. Tong, G.A. Stouffer, N.R. Madamanchi, and M.S. Runge Mitochondrial oxidative stress in aortic stiffening with age: the role of smooth muscle cell function Arterioscler. Thromb. Vasc. Biol. 32 2012 745 755
-
(2012)
Arterioscler. Thromb. Vasc. Biol.
, vol.32
, pp. 745-755
-
-
Zhou, R.H.1
Vendrov, A.E.2
Tchivilev, I.3
Niu, X.L.4
Molnar, K.C.5
Rojas, M.6
Carter, J.D.7
Tong, H.8
Stouffer, G.A.9
Madamanchi, N.R.10
Runge, M.S.11
-
110
-
-
77953953488
-
P66Shc signals to age
-
M. Trinei, I. Berniakovich, E. Beltrami, E. Migliaccio, A. Fassina, P. Pelicci, and M. Giorgio P66Shc signals to age Aging (Albany NY) 1 2009 503 510
-
(2009)
Aging (Albany NY)
, vol.1
, pp. 503-510
-
-
Trinei, M.1
Berniakovich, I.2
Beltrami, E.3
Migliaccio, E.4
Fassina, A.5
Pelicci, P.6
Giorgio, M.7
-
111
-
-
0033581704
-
shc adaptor protein controls oxidative stress response and life span in mammals
-
E. Migliaccio, M. Giorgio, S. Mele, G. Pelicci, P. Reboldi, P.P. Pandolfi, L. Lanfrancone, and P.G. Pelicci The p66shc adaptor protein controls oxidative stress response and life span in mammals Nature 402 1999 309 313 (Pubitemid 129516269)
-
(1999)
Nature
, vol.402
, Issue.6759
, pp. 309-313
-
-
Migllaccio, E.1
Giorgio, M.2
Mele, S.3
Pelicci, G.4
Reboldl, P.5
Pandolfi, P.P.6
Lanfrancone, L.7
Pelicci, P.G.8
-
112
-
-
21344454467
-
shc is highly expressed in fibroblasts from centenarians
-
DOI 10.1016/j.mad.2005.03.004, PII S0047637405000667
-
S. Pandolfi, M. Bonafe, L. Di Tella, L. Tiberi, S. Salvioli, D. Monti, S. Sorbi, and C. Franceschi p66(shc) is highly expressed in fibroblasts from centenarians Mech. Ageing Dev. 126 2005 839 844 (Pubitemid 40909779)
-
(2005)
Mechanisms of Ageing and Development
, vol.126
, Issue.8
, pp. 839-844
-
-
Pandolfi, S.1
Bonafe, M.2
Di Tella, L.3
Tiberi, L.4
Salvioli, S.5
Monti, D.6
Sorbi, S.7
Franceschi, C.8
-
113
-
-
27644570778
-
P66shc regulates endothelial NO production and endothelium-dependent vasorelaxation: Implications for age-associated vascular dysfunction
-
DOI 10.1016/j.yjmcc.2005.09.003, PII S0022282805002828
-
T. Yamamori, A.R. White, I. Mattagajasingh, F.A. Khanday, A. Haile, B. Qi, B.H. Jeon, A. Bugayenko, K. Kasuno, D.E. Berkowitz, and K. Irani P66shc regulates endothelial NO production and endothelium-dependent vasorelaxation: implications for age-associated vascular dysfunction J. Mol. Cell. Cardiol. 39 2005 992 995 (Pubitemid 41572332)
-
(2005)
Journal of Molecular and Cellular Cardiology
, vol.39
, Issue.6
, pp. 992-995
-
-
Yamamori, T.1
White, A.R.2
Mattagajasingh, I.3
Khanday, F.A.4
Haile, A.5
Qi, B.6
Byeong, H.J.7
Bugayenko, A.8
Kasuno, K.9
Berkowitz, D.E.10
Irani, K.11
-
114
-
-
57049189743
-
The role of p66Shc deletion in age-associated arterial dysfunction and disease states
-
G.G. Camici, F. Cosentino, F.C. Tanner, and T.F. Luscher The role of p66Shc deletion in age-associated arterial dysfunction and disease states J. Appl. Physiol. 105 2008 1628 1631
-
(2008)
J. Appl. Physiol.
, vol.105
, pp. 1628-1631
-
-
Camici, G.G.1
Cosentino, F.2
Tanner, F.C.3
Luscher, T.F.4
-
115
-
-
42249097446
-
Final common molecular pathways of aging and cardiovascular disease: Role of the p66Shc protein
-
DOI 10.1161/ATVBAHA.107.156059
-
F. Cosentino, P. Francia, G.G. Camici, P.G. Pelicci, T.F. Luscher, and M. Volpe Final common molecular pathways of aging and cardiovascular disease: role of the p66Shc protein Arterioscler. Thromb. Vasc. Biol. 28 2008 622 628 (Pubitemid 351651330)
-
(2008)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.28
, Issue.4
, pp. 622-628
-
-
Cosentino, F.1
Francia, P.2
Camici, G.G.3
Pelicci, P.G.4
Luscher, T.F.5
-
116
-
-
77953741269
-
Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2
-
Z. Ungvari, Z. Bagi, A. Feher, F.A. Recchia, W.E. Sonntag, K. Pearson, R. de Cabo, and A. Csiszar Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2 Am. J. Physiol. Heart Circ. Physol 299 2010 H18 H24
-
(2010)
Am. J. Physiol. Heart Circ. Physol
, vol.299
-
-
Ungvari, Z.1
Bagi, Z.2
Feher, A.3
Recchia, F.A.4
Sonntag, W.E.5
Pearson, K.6
De Cabo, R.7
Csiszar, A.8
-
117
-
-
79959691138
-
Antiproliferative effect of estrogen in vascular smooth muscle cells is mediated by Kruppel-like factor-4 and manganese superoxide dismutase
-
D. Sivritas, M.U. Becher, T. Ebrahimian, O. Arfa, S. Rapp, A. Bohner, C.F. Mueller, T. Umemura, S. Wassmann, G. Nickenig, and K. Wassmann Antiproliferative effect of estrogen in vascular smooth muscle cells is mediated by Kruppel-like factor-4 and manganese superoxide dismutase Basic Res. Cardiol. 106 2011 563 575
-
(2011)
Basic Res. Cardiol.
, vol.106
, pp. 563-575
-
-
Sivritas, D.1
Becher, M.U.2
Ebrahimian, T.3
Arfa, O.4
Rapp, S.5
Bohner, A.6
Mueller, C.F.7
Umemura, T.8
Wassmann, S.9
Nickenig, G.10
Wassmann, K.11
-
118
-
-
79551703801
-
Kruppel-like factor 2 improves neovascularization capacity of aged proangiogenic cells
-
R.A. Boon, C. Urbich, A. Fischer, R.D. Fontijn, F.H. Seeger, M. Koyanagi, A.J. Horrevoets, and S. Dimmeler Kruppel-like factor 2 improves neovascularization capacity of aged proangiogenic cells Eur. Heart J. 32 2011 371 377
-
(2011)
Eur. Heart J.
, vol.32
, pp. 371-377
-
-
Boon, R.A.1
Urbich, C.2
Fischer, A.3
Fontijn, R.D.4
Seeger, F.H.5
Koyanagi, M.6
Horrevoets, A.J.7
Dimmeler, S.8
-
119
-
-
0034859820
-
Oxidation of zinc finger transcription factors: Physiological consequences
-
K.A. Webster, H. Prentice, and N.H. Bishopric Oxidation of zinc finger transcription factors: physiological consequences Antioxid. Redox Signal. 3 2001 535 548 (Pubitemid 32785979)
-
(2001)
Antioxidants and Redox Signaling
, vol.3
, Issue.4
, pp. 535-548
-
-
Webster, K.A.1
Prentice, H.2
Bishopric, N.H.3
-
120
-
-
33847620225
-
Aging: A revisited theory based on free radicals generated by NOX family NADPH oxidases
-
K.H. Krause Aging: a revisited theory based on free radicals generated by NOX family NADPH oxidases Exp. Gerontol 42 2007 256 262
-
(2007)
Exp. Gerontol
, vol.42
, pp. 256-262
-
-
Krause, K.H.1
-
121
-
-
1842423370
-
Distinct Subcellular Localizations of Nox1 and Nox4 in Vascular Smooth Muscle Cells
-
DOI 10.1161/01.ATV.0000112024.13727.2c
-
L.L. Hilenski, R.E. Clempus, M.T. Quinn, J.D. Lambeth, and K.K. Griendling Distinct subcellular localizations of Nox1 and Nox4 in vascular smooth muscle cells Arterioscler. Thromb. Vasc. Biol. 24 2004 677 683 (Pubitemid 38451603)
-
(2004)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.24
, Issue.4
, pp. 677-683
-
-
Hilenski, L.L.1
Clempus, R.E.2
Quinn, M.T.3
Lambeth, J.D.4
Griendling, K.K.5
-
122
-
-
33750845370
-
Expression of phagocyte NADPH oxidase components in human endothelial cells
-
S.A. Jones, V.B. O'Donnell, J.D. Wood, J.P. Broughton, E.J. Hughes, and O.T. Jones Expression of phagocyte NADPH oxidase components in human endothelial cells Am. J. Physiol. 271 1996 H1626 H1634
-
(1996)
Am. J. Physiol.
, vol.271
-
-
Jones, S.A.1
O'Donnell, V.B.2
Wood, J.D.3
Broughton, J.P.4
Hughes, E.J.5
Jones, O.T.6
-
123
-
-
0037076798
-
Expression of a functionally active gp91phox-containing neutrophil-type NAD(P)H oxidase in smooth muscle cells from human resistance arteries: Regulation by angiotensin II
-
DOI 10.1161/01.RES.0000020404.01971.2F
-
R.M. Touyz, X. Chen, F. Tabet, G. Yao, G. He, M.T. Quinn, P.J. Pagano, and E.L. Schiffrin Expression of a functionally active gp91phox-containing neutrophil-type NAD(P)H oxidase in smooth muscle cells from human resistance arteries: regulation by angiotensin II Circ. Res. 90 2002 1205 1213 (Pubitemid 34786906)
-
(2002)
Circulation Research
, vol.90
, Issue.11
, pp. 1205-1213
-
-
Touyz, R.M.1
Chen, X.2
Tabet, F.3
Yao, G.4
He, G.5
Quinn, M.T.6
Pagano, P.J.7
Schiffrin, E.L.8
-
124
-
-
53549113038
-
Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production
-
S.I. Dikalov, A.E. Dikalova, A.T. Bikineyeva, H.H. Schmidt, D.G. Harrison, and K.K. Griendling Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production Free Radic. Biol. Med. 45 2008 1340 1351
-
(2008)
Free Radic. Biol. Med.
, vol.45
, pp. 1340-1351
-
-
Dikalov, S.I.1
Dikalova, A.E.2
Bikineyeva, A.T.3
Schmidt, H.H.4
Harrison, D.G.5
Griendling, K.K.6
-
125
-
-
9144255403
-
Nox4 as the Major Catalytic Component of an Endothelial NAD(P)H Oxidase
-
DOI 10.1161/01.CIR.0000105680.92873.70
-
T. Ago, T. Kitazono, H. Ooboshi, T. Iyama, Y.H. Han, J. Takada, M. Wakisaka, S. Ibayashi, H. Utsumi, and M. Iida Nox4 as the major catalytic component of an endothelial NAD(P)H oxidase Circulation 109 2004 227 233 (Pubitemid 38114144)
-
(2004)
Circulation
, vol.109
, Issue.2
, pp. 227-233
-
-
Ago, T.1
Kitazono, T.2
Ooboshi, H.3
Iyama, T.4
Han, Y.H.5
Takada, J.6
Wakisaka, M.7
Ibayashi, S.8
Utsumi, H.9
Iida, M.10
-
126
-
-
79953881843
-
The E-loop is involved in hydrogen peroxide formation by the NADPH oxidase Nox4
-
I. Takac, K. Schroder, L. Zhang, B. Lardy, N. Anilkumar, J.D. Lambeth, A.M. Shah, F. Morel, and R.P. Brandes The E-loop is involved in hydrogen peroxide formation by the NADPH oxidase Nox4 J. Biol. Chem. 286 2011 13304 13313
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 13304-13313
-
-
Takac, I.1
Schroder, K.2
Zhang, L.3
Lardy, B.4
Anilkumar, N.5
Lambeth, J.D.6
Shah, A.M.7
Morel, F.8
Brandes, R.P.9
-
127
-
-
55949095391
-
Calcium-dependent NOX5 nicotinamide adenine dinucleotide phosphate oxidase contributes to vascular oxidative stress in human coronary artery disease
-
T.J. Guzik, W. Chen, M.C. Gongora, B. Guzik, H.E. Lob, D. Mangalat, N. Hoch, S. Dikalov, P. Rudzinski, B. Kapelak, J. Sadowski, and D.G. Harrison Calcium-dependent NOX5 nicotinamide adenine dinucleotide phosphate oxidase contributes to vascular oxidative stress in human coronary artery disease J. Am. Coll. Cardiol. 52 2008 1803 1809
-
(2008)
J. Am. Coll. Cardiol.
, vol.52
, pp. 1803-1809
-
-
Guzik, T.J.1
Chen, W.2
Gongora, M.C.3
Guzik, B.4
Lob, H.E.5
Mangalat, D.6
Hoch, N.7
Dikalov, S.8
Rudzinski, P.9
Kapelak, B.10
Sadowski, J.11
Harrison, D.G.12
-
128
-
-
33745234267
-
NADPH oxidases are in part responsible for increased cardiovascular superoxide production during aging
-
DOI 10.1016/j.freeradbiomed.2006.02.020, PII S0891584906001572
-
A. Oudot, C. Martin, D. Busseuil, C. Vergely, L. Demaison, and L. Rochette NADPH oxidases are in part responsible for increased cardiovascular superoxide production during aging Free Radic. Biol. Med. 40 2006 2214 2222 (Pubitemid 43922397)
-
(2006)
Free Radical Biology and Medicine
, vol.40
, Issue.12
, pp. 2214-2222
-
-
Oudot, A.1
Martin, C.2
Busseuil, D.3
Vergely, C.4
Demaison, L.5
Rochette, L.6
-
129
-
-
65349104490
-
Upregulation of Nox4 in the aging vasculature and its association with smooth muscle cell polyploidy
-
D.J. McCrann, D. Yang, H. Chen, S. Carroll, and K. Ravid Upregulation of Nox4 in the aging vasculature and its association with smooth muscle cell polyploidy Cell Cycle 8 2009 902 908
-
(2009)
Cell Cycle
, vol.8
, pp. 902-908
-
-
McCrann, D.J.1
Yang, D.2
Chen, H.3
Carroll, S.4
Ravid, K.5
-
130
-
-
72249100352
-
Abnormal nitric oxide production in aged rat mesenteric arteries is mediated by NAD(P)H oxidase-derived peroxide
-
X. Zhou, H.G. Bohlen, J.L. Unthank, and S.J. Miller Abnormal nitric oxide production in aged rat mesenteric arteries is mediated by NAD(P)H oxidase-derived peroxide Am. J. Physiol. Heart Circ. Physol 297 2009 H2227 H2233
-
(2009)
Am. J. Physiol. Heart Circ. Physol
, vol.297
-
-
Zhou, X.1
Bohlen, H.G.2
Unthank, J.L.3
Miller, S.J.4
-
131
-
-
78651377497
-
Chronic intake of red wine polyphenols by young rats prevents aging-induced endothelial dysfunction and decline in physical performance: Role of NADPH oxidase
-
S. Dal-Ros, J. Zoll, A.L. Lang, C. Auger, N. Keller, C. Bronner, B. Geny, and V.B. Schini-Kerth Chronic intake of red wine polyphenols by young rats prevents aging-induced endothelial dysfunction and decline in physical performance: role of NADPH oxidase Biochem. Biophys. Res. Commun. 404 2011 743 749
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.404
, pp. 743-749
-
-
Dal-Ros, S.1
Zoll, J.2
Lang, A.L.3
Auger, C.4
Keller, N.5
Bronner, C.6
Geny, B.7
Schini-Kerth, V.B.8
-
132
-
-
67650354412
-
Voluntary wheel running restores endothelial function in conduit arteries of old mice: Direct evidence for reduced oxidative stress, increased superoxide dismutase activity and down-regulation of NADPH oxidase
-
J.R. Durrant, D.R. Seals, M.L. Connell, M.J. Russell, B.R. Lawson, B.J. Folian, A.J. Donato, and L.A. Lesniewski Voluntary wheel running restores endothelial function in conduit arteries of old mice: direct evidence for reduced oxidative stress, increased superoxide dismutase activity and down-regulation of NADPH oxidase J. Physiol. 587 2009 3271 3285
-
(2009)
J. Physiol.
, vol.587
, pp. 3271-3285
-
-
Durrant, J.R.1
Seals, D.R.2
Connell, M.L.3
Russell, M.J.4
Lawson, B.R.5
Folian, B.J.6
Donato, A.J.7
Lesniewski, L.A.8
-
133
-
-
4744360664
-
NADPH oxidase and ERK signaling regulates hyperoxia-induced Nrf2-ARE transcriptional response in pulmonary epithelial cells
-
DOI 10.1074/jbc.M408275200
-
S. Papaiahgari, S.R. Kleeberger, H.Y. Cho, D.V. Kalvakolanu, and S.P. Reddy NADPH oxidase and ERK signaling regulates hyperoxia-induced Nrf2-ARE transcriptional response in pulmonary epithelial cells J. Biol. Chem. 279 2004 42302 42312 (Pubitemid 39313679)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.40
, pp. 42302-42312
-
-
Papaiahgari, S.1
Kleeberger, S.R.2
Cho, H.-Y.3
Kalvakolanu, D.V.4
Reddy, S.P.5
-
134
-
-
79957954491
-
Nox4 regulates Nrf2 and glutathione redox in cardiomyocytes in vivo
-
A.C. Brewer, T.V. Murray, M. Arno, M. Zhang, N.P. Anilkumar, G.E. Mann, and A.M. Shah Nox4 regulates Nrf2 and glutathione redox in cardiomyocytes in vivo Free Radic. Biol. Med. 51 2011 205 215
-
(2011)
Free Radic. Biol. Med.
, vol.51
, pp. 205-215
-
-
Brewer, A.C.1
Murray, T.V.2
Arno, M.3
Zhang, M.4
Anilkumar, N.P.5
Mann, G.E.6
Shah, A.M.7
-
135
-
-
77957350902
-
PPAR{gamma} regulates hypoxia-induced Nox4 expression in human pulmonary artery smooth muscle cells through NF-{kappa}B
-
X. Lu, T.C. Murphy, M.S. Nanes, and C.M. Hart PPAR{gamma} regulates hypoxia-induced Nox4 expression in human pulmonary artery smooth muscle cells through NF-{kappa}B Am. J. Physiol. Lung Cell Mol. Physiol 299 2010 L559 L566
-
(2010)
Am. J. Physiol. Lung Cell Mol. Physiol
, vol.299
-
-
Lu, X.1
Murphy, T.C.2
Nanes, M.S.3
Hart, C.M.4
-
136
-
-
77953518507
-
The NADPH oxidase subunit NOX4 is a new target gene of the hypoxia-inducible factor-1
-
I. Diebold, A. Petry, J. Hess, and A. Gorlach The NADPH oxidase subunit NOX4 is a new target gene of the hypoxia-inducible factor-1 Mol. Biol. Cell 21 2010 2087 2096
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 2087-2096
-
-
Diebold, I.1
Petry, A.2
Hess, J.3
Gorlach, A.4
-
137
-
-
79956121323
-
Nrf2 regulates hyperoxia-induced Nox4 expression in human lung endothelium: Identification of functional antioxidant response elements on the Nox4 promoter
-
S. Pendyala, J. Moitra, S. Kalari, S.R. Kleeberger, Y. Zhao, S.P. Reddy, J.G. Garcia, and V. Natarajan Nrf2 regulates hyperoxia-induced Nox4 expression in human lung endothelium: identification of functional antioxidant response elements on the Nox4 promoter Free Radic. Biol. Med. 50 2011 1749 1759
-
(2011)
Free Radic. Biol. Med.
, vol.50
, pp. 1749-1759
-
-
Pendyala, S.1
Moitra, J.2
Kalari, S.3
Kleeberger, S.R.4
Zhao, Y.5
Reddy, S.P.6
Garcia, J.G.7
Natarajan, V.8
-
138
-
-
85027947365
-
Age-related changes in xanthine oxidase activity and lipid peroxidation, as well as in the correlation between both parameters, in plasma and several organs from female mice
-
C. Vida, I. Corpas, M. De la Fuente, and E.M. Gonzalez Age-related changes in xanthine oxidase activity and lipid peroxidation, as well as in the correlation between both parameters, in plasma and several organs from female mice J. Physiol. Biochem 67 2011 551 558
-
(2011)
J. Physiol. Biochem
, vol.67
, pp. 551-558
-
-
Vida, C.1
Corpas, I.2
De La Fuente, M.3
Gonzalez, E.M.4
-
139
-
-
33749819577
-
Oxidative stress-associated vascular aging is xanthine oxidase-dependent but not NAD(P)H oxidase-dependent
-
DOI 10.1097/01.fjc.0000245402.62864.0a, PII 0000534420060900000003
-
M.A. Newaz, Z. Yousefipour, and A. Oyekan Oxidative stress-associated vascular aging is xanthine oxidase-dependent but not NAD(P)H oxidase-dependent J. Cardiovasc. Pharmacol. 48 2006 88 94 (Pubitemid 44562947)
-
(2006)
Journal of Cardiovascular Pharmacology
, vol.48
, Issue.3
, pp. 88-94
-
-
Newaz, M.A.1
Yousefipour, Z.2
Oyekan, A.3
-
140
-
-
36048983398
-
Age-related increase in xanthine oxidase activity in human plasma and rat tissues
-
DOI 10.1080/10715760701481461, PII 782740962
-
R. Aranda, E. Domenech, A.D. Rus, J.T. Real, J. Sastre, J. Vina, and F.V. Pallardo Age-related increase in xanthine oxidase activity in human plasma and
-
(2007)
Free Radical Research
, vol.41
, Issue.11
, pp. 1195-1200
-
-
Aranda, R.1
Domenech, E.2
Rus, A.D.3
Real, J.T.4
Sastre, J.5
Vina, J.6
Pallardo, F.7
-
141
-
-
0037076784
-
Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function
-
DOI 10.1161/01.RES.0000020401.61826.EA
-
A. Csiszar, Z. Ungvari, J.G. Edwards, P. Kaminski, M.S. Wolin, A. Koller, and G. Kaley Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function Circ. Res. 90 2002 1159 1166 (Pubitemid 34786900)
-
(2002)
Circulation Research
, vol.90
, Issue.11
, pp. 1159-1166
-
-
Csiszar, A.1
Ungvari, Z.2
Edwards, J.G.3
Kaminski, P.4
Wolin, M.S.5
Koller, A.6
Kaley, G.7
-
142
-
-
79957969884
-
Inhibition of xanthine oxidase reduces oxidative stress and improves skeletal muscle function in response to electrically stimulated isometric contractions in aged mice
-
M.J. Ryan, J.R. Jackson, Y. Hao, S.S. Leonard, and S.E. Alway Inhibition of xanthine oxidase reduces oxidative stress and improves skeletal muscle function in response to electrically stimulated isometric contractions in aged mice Free Radic. Biol. Med. 51 2011 38 52
-
(2011)
Free Radic. Biol. Med.
, vol.51
, pp. 38-52
-
-
Ryan, M.J.1
Jackson, J.R.2
Hao, Y.3
Leonard, S.S.4
Alway, S.E.5
-
143
-
-
34548452155
-
Aging enhances pressure-induced arterial superoxide formation
-
A. Jacobson, C. Yan, Q. Gao, T. Rincon-Skinner, A. Rivera, J. Edwards, A. Huang, G. Kaley, and D. Sun Aging enhances pressure-induced arterial superoxide formation Am. J. Physiol. Heart Circ. Physol 293 2007 H1344 H1350
-
(2007)
Am. J. Physiol. Heart Circ. Physol
, vol.293
-
-
Jacobson, A.1
Yan, C.2
Gao, Q.3
Rincon-Skinner, T.4
Rivera, A.5
Edwards, J.6
Huang, A.7
Kaley, G.8
Sun, D.9
-
144
-
-
33644672363
-
Xanthine oxidase does not contribute to impaired peripheral conduit artery endothelium-dependent dilatation with ageing
-
DOI 10.1113/jphysiol.2005.102566
-
I. Eskurza, Z.D. Kahn, and D.R. Seals Xanthine oxidase does not contribute to impaired peripheral conduit artery endothelium-dependent dilatation with ageing J. Physiol. 571 2006 661 668 (Pubitemid 43329554)
-
(2006)
Journal of Physiology
, vol.571
, Issue.3
, pp. 661-668
-
-
Eskurza, I.1
Kahn, Z.D.2
Seals, D.R.3
-
145
-
-
33645780634
-
Endothelial nitric oxide synthase in vascular disease: From marvel to menace
-
U. Forstermann, and T. Munzel Endothelial nitric oxide synthase in vascular disease: from marvel to menace Circulation 113 2006 1708 1714
-
(2006)
Circulation
, vol.113
, pp. 1708-1714
-
-
Forstermann, U.1
Munzel, T.2
-
146
-
-
0035805555
-
Oxygen Reduction by Nitric-oxide Synthases
-
DOI 10.1074/jbc.R100011200
-
D. Stuehr, S. Pou, and G.M. Rosen Oxygen reduction by nitric-oxide synthases J. Biol. Chem. 276 2001 14533 14536 (Pubitemid 37373319)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.18
, pp. 14533-14536
-
-
Stuehr, D.1
Pou, S.2
Rosen, G.M.3
-
147
-
-
0037399439
-
Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension
-
DOI 10.1172/JCI200314172
-
U. Landmesser, S. Dikalov, S.R. Price, L. McCann, T. Fukai, S.M. Holland, W.E. Mitch, and D.G. Harrison Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension J. Clin. Invest. 111 2003 1201 1209 (Pubitemid 36519937)
-
(2003)
Journal of Clinical Investigation
, vol.111
, Issue.8
, pp. 1201-1209
-
-
Landmesser, U.1
Dikalov, S.2
Price, S.R.3
McCann, L.4
Fukai, T.5
Holland, S.M.6
Mitch, W.E.7
Harrison, D.G.8
-
148
-
-
0033527413
-
Oxidation of tetrahydrobiopterin by peroxynitrite: Implications for vascular endothelial function
-
DOI 10.1006/bbrc.1999.1422
-
S. Milstien, and Z. Katusic Oxidation of tetrahydrobiopterin by peroxynitrite: implications for vascular endothelial function Biochem. Biophys. Res. Commun. 263 1999 681 684 (Pubitemid 29490686)
-
(1999)
Biochemical and Biophysical Research Communications
, vol.263
, Issue.3
, pp. 681-684
-
-
Milstien, S.1
Katusic, Z.2
-
149
-
-
0035814951
-
Endothelial regulation of vasomotion in ApoE-deficient mice: Implications for interactions between peroxynitrite and tetrahydrobiopterin
-
J.B. Laursen, M. Somers, S. Kurz, L. McCann, A. Warnholtz, B.A. Freeman, M. Tarpey, T. Fukai, and D.G. Harrison Endothelial regulation of vasomotion in apoE-deficient mice: implications for interactions between peroxynitrite and tetrahydrobiopterin Circulation 103 2001 1282 1288 (Pubitemid 32221353)
-
(2001)
Circulation
, vol.103
, Issue.9
, pp. 1282-1288
-
-
Laursen, J.B.1
Somers, M.2
Kurz, S.3
McCann, L.4
Warnholtz, A.5
Freeman, B.A.6
Tarpey, M.7
Fukai, T.8
Harrison, D.G.9
-
150
-
-
37349111784
-
Oxidative stress, nitric oxide synthase, and superoxide dismutase: A matter of imbalance underlies endothelial dysfunction in the human coronary circulation
-
DOI 10.1161/HYPERTENSIONAHA.107.103226, PII 0000426820080100000007
-
E.L. Schiffrin Oxidative stress, nitric oxide synthase, and superoxide dismutase: a matter of imbalance underlies endothelial dysfunction in the human coronary circulation Hypertension 51 2008 31 32 (Pubitemid 350307097)
-
(2008)
Hypertension
, vol.51
, Issue.1
, pp. 31-32
-
-
Schiffrin, E.L.1
-
151
-
-
39449118560
-
Ageing diminishes endothelium-dependent vasodilatation and tetrahydrobiopterin content in rat skeletal muscle arterioles
-
DOI 10.1113/jphysiol.2007.147686
-
M.D. Delp, B.J. Behnke, S.A. Spier, G. Wu, and J.M. Muller-Delp Ageing diminishes endothelium-dependent vasodilatation and tetrahydrobiopterin content in rat skeletal muscle arterioles J. Physiol. 586 2008 1161 1168 (Pubitemid 351267353)
-
(2008)
Journal of Physiology
, vol.586
, Issue.4
, pp. 1161-1168
-
-
Delp, M.D.1
Behnke, B.J.2
Spier, S.A.3
Wu, G.4
Muller-Delp, J.M.5
-
152
-
-
33748645122
-
5-Methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: Effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling
-
DOI 10.1161/CIRCULATIONAHA.106.612325, PII 0000301720060912000012
-
C. Antoniades, C. Shirodaria, N. Warrick, S. Cai, J. de Bono, J. Lee, P. Leeson, S. Neubauer, C. Ratnatunga, R. Pillai, H. Refsum, and K.M. Channon 5-Methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling Circulation 114 2006 1193 1201 (Pubitemid 44386484)
-
(2006)
Circulation
, vol.114
, Issue.11
, pp. 1193-1201
-
-
Antoniades, C.1
Shirodaria, C.2
Warrick, N.3
Cai, S.4
De Bono, J.5
Lee, J.6
Leeson, P.7
Neubauer, S.8
Ratnatunga, C.9
Pillai, R.10
Refsum, H.11
Channon, K.M.12
-
153
-
-
9344256749
-
Mechanisms of aging-induced impairment of endothelium-dependent relaxation: Role of tetrahydrobiopterin
-
K.A. Blackwell, J.P. Sorenson, D.M. Richardson, L.A. Smith, O. Suda, K. Nath, and Z.S. Katusic Mechanisms of aging-induced impairment of endothelium-dependent relaxation: role of tetrahydrobiopterin Am. J. Physiol. Heart Circ. Physol 287 2004 H2448 H2453
-
(2004)
Am. J. Physiol. Heart Circ. Physol
, vol.287
-
-
Blackwell, K.A.1
Sorenson, J.P.2
Richardson, D.M.3
Smith, L.A.4
Suda, O.5
Nath, K.6
Katusic, Z.S.7
-
154
-
-
79955526629
-
Hyperactive S6K1 mediates oxidative stress and endothelial dysfunction in aging: Inhibition by resveratrol
-
A.G. Rajapakse, G. Yepuri, J.M. Carvas, S. Stein, C.M. Matter, I. Scerri, J. Ruffieux, J.P. Montani, X.F. Ming, and Z. Yang Hyperactive S6K1 mediates oxidative stress and endothelial dysfunction in aging: inhibition by resveratrol PLoS One 6 2011 e19237
-
(2011)
PLoS One
, vol.6
, pp. 19237
-
-
Rajapakse, A.G.1
Yepuri, G.2
Carvas, J.M.3
Stein, S.4
Matter, C.M.5
Scerri, I.6
Ruffieux, J.7
Montani, J.P.8
Ming, X.F.9
Yang, Z.10
-
155
-
-
0033639306
-
Asymmetric dimethylarginine, derangements of the endothelial nitric oxide synthase pathway, and cardiovascular diseases
-
R.H. Boger, and S.M. Bode-Boger Asymmetric dimethylarginine, derangements of the endothelial nitric oxide synthase pathway, and cardiovascular diseases Semin. Thromb. Hemost. 26 2000 539 545
-
(2000)
Semin. Thromb. Hemost.
, vol.26
, pp. 539-545
-
-
Boger, R.H.1
Bode-Boger, S.M.2
-
156
-
-
0141607693
-
Oral L-arginine improves endothelial function in healthy individuals older than 70 years
-
DOI 10.1191/1358863x03vm474oa
-
S.M. Bode-Boger, J. Muke, A. Surdacki, G. Brabant, R.H. Boger, and J.C. Frolich Oral L-arginine improves endothelial function in healthy individuals older than 70 years Vasc. Med 8 2003 77 81 (Pubitemid 37168247)
-
(2003)
Vascular Medicine
, vol.8
, Issue.2
, pp. 77-81
-
-
Bode-Boger, S.M.1
Muke, J.2
Surdacki, A.3
Brabant, G.4
Boger, R.H.5
Frolich, J.C.6
-
157
-
-
33845502720
-
Acute ascorbate supplementation alone or combined with arginase inhibition augments reflex cutaneous vasodilation in aged human skin
-
L.A. Holowatz, C.S. Thompson, and W.L. Kenney Acute ascorbate supplementation alone or combined with arginase inhibition augments reflex cutaneous vasodilation in aged human skin Am. J. Physiol. Heart Circ. Physol 291 2006 H2965 H2970
-
(2006)
Am. J. Physiol. Heart Circ. Physol
, vol.291
-
-
Holowatz, L.A.1
Thompson, C.S.2
Kenney, W.L.3
-
158
-
-
33846159514
-
Impaired flow-mediated dilation with age is not explained by L-arginine bioavailability or endothelial asymmetric dimethylarginine protein expression
-
DOI 10.1152/japplphysiol.00660.2006
-
P.E. Gates, M.L. Boucher, A.E. Silver, K.D. Monahan, and D.R. Seals Impaired flow-mediated dilation with age is not explained by L-arginine bioavailability or endothelial asymmetric dimethylarginine protein expression J. Appl. Physiol. 102 2007 63 71 (Pubitemid 46089752)
-
(2007)
Journal of Applied Physiology
, vol.102
, Issue.1
, pp. 63-71
-
-
Gates, P.E.1
Boucher, M.L.2
Silver, A.E.3
Monahan, K.D.4
Seals, D.R.5
-
159
-
-
1342301460
-
An age-related decline in endothelial function is not associated with alterations in L-arginine transport in humans
-
DOI 10.1097/00004872-200402000-00016
-
B.A. Ahlers, M.M. Parnell, J.P. Chin-Dusting, and D.M. Kaye An age-related decline in endothelial function is not associated with alterations in L-arginine transport in humans J. Hypertens. 22 2004 321 327 (Pubitemid 38250991)
-
(2004)
Journal of Hypertension
, vol.22
, Issue.2
, pp. 321-327
-
-
Ahlers, B.A.1
Parnell, M.M.2
Chin-Dusting, J.P.F.3
Kaye, D.M.4
-
161
-
-
0142023863
-
Arginase Reciprocally Regulates Nitric Oxide Synthase Activity and Contributes to Endothelial Dysfunction in Aging Blood Vessels
-
DOI 10.1161/01.CIR.0000092948.04444.C7
-
D.E. Berkowitz, R. White, D. Li, K.M. Minhas, A. Cernetich, S. Kim, S. Burke, A.A. Shoukas, D. Nyhan, H.C. Champion, and J.M. Hare Arginase reciprocally regulates nitric oxide synthase activity and contributes to endothelial dysfunction in aging blood vessels Circulation 108 2003 2000 2006 (Pubitemid 37296546)
-
(2003)
Circulation
, vol.108
, Issue.16
, pp. 2000-2006
-
-
Berkowitz, D.E.1
White, R.2
Li, D.3
Minhas, K.M.4
Cernetich, A.5
Kim, S.6
Burke, S.7
Shoukas, A.A.8
Nyhan, D.9
Champion, H.C.10
Hare, J.M.11
-
162
-
-
34848861137
-
Inducible NO synthase-dependent S-nitrosylation and activation of arginase1 contribute to age-related endothelial dysfunction
-
DOI 10.1161/CIRCRESAHA.107.157727, PII 0000301220070928000011
-
L. Santhanam, H.K. Lim, H.K. Lim, V. Miriel, T. Brown, M. Patel, S. Balanson, S. Ryoo, M. Anderson, K. Irani, F. Khanday, L. Di Costanzo, D. Nyhan, J.M. Hare, D.W. Christianson, R. Rivers, A. Shoukas, and D.E. Berkowitz Inducible NO synthase dependent S-nitrosylation and activation of arginase1 contribute to age-related endothelial dysfunction Circ. Res. 101 2007 692 702 (Pubitemid 47494100)
-
(2007)
Circulation Research
, vol.101
, Issue.7
, pp. 692-702
-
-
Santhanam, L.1
Lim, H.K.2
Lim, H.K.3
Miriel, V.4
Brown, T.5
Patel, M.6
Balanson, S.7
Ryoo, S.8
Anderson, M.9
Irani, K.10
Khanday, F.11
Di Costanzo, L.12
Nyhan, D.13
Hare, J.M.14
Christianson, D.W.15
Rivers, R.16
Shoukas, A.17
Berkowitz, D.E.18
-
163
-
-
31944447852
-
Knockdown of arginase I restores NO signaling in the vasculature of old rats
-
DOI 10.1161/01.HYP.0000198543.34502.d7
-
A.R. White, S. Ryoo, D. Li, H.C. Champion, J. Steppan, D. Wang, D. Nyhan, A.A. Shoukas, J.M. Hare, and D.E. Berkowitz Knockdown of arginase I restores NO signaling in the vasculature of old rats Hypertension 47 2006 245 251 (Pubitemid 43189770)
-
(2006)
Hypertension
, vol.47
, Issue.2
, pp. 245-251
-
-
White, A.R.1
Ryoo, S.2
Li, D.3
Champion, H.C.4
Steppan, J.5
Wang, D.6
Nyhan, D.7
Shoukas, A.A.8
Hare, J.M.9
Berkowitz, D.E.10
-
164
-
-
33745740349
-
L-Arginine supplementation or arginase inhibition augments reflex cutaneous vasodilatation in aged human skin
-
L.A. Holowatz, C.S. Thompson, and W.L. Kenney L-Arginine supplementation or arginase inhibition augments reflex cutaneous vasodilatation in aged human skin J. Physiol. 574 2006 573 581
-
(2006)
J. Physiol.
, vol.574
, pp. 573-581
-
-
Holowatz, L.A.1
Thompson, C.S.2
Kenney, W.L.3
-
165
-
-
70350117109
-
Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats
-
J.H. Kim, L.J. Bugaj, Y.J. Oh, T.J. Bivalacqua, S. Ryoo, K.G. Soucy, L. Santhanam, A. Webb, A. Camara, G. Sikka, D. Nyhan, A.A. Shoukas, M. Ilies, D.W. Christianson, H.C. Champion, and D.E. Berkowitz Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats J. Appl. Physiol. 107 2009 1249 1257
-
(2009)
J. Appl. Physiol.
, vol.107
, pp. 1249-1257
-
-
Kim, J.H.1
Bugaj, L.J.2
Oh, Y.J.3
Bivalacqua, T.J.4
Ryoo, S.5
Soucy, K.G.6
Santhanam, L.7
Webb, A.8
Camara, A.9
Sikka, G.10
Nyhan, D.11
Shoukas, A.A.12
Ilies, M.13
Christianson, D.W.14
Champion, H.C.15
Berkowitz, D.E.16
-
166
-
-
0033813512
-
Does ADMA cause endothelial dysfunction?
-
J.P. Cooke Does ADMA cause endothelial dysfunction? Arterioscler. Thromb. Vasc. Biol. 20 2000 2032 2037
-
(2000)
Arterioscler. Thromb. Vasc. Biol.
, vol.20
, pp. 2032-2037
-
-
Cooke, J.P.1
-
167
-
-
0033594888
-
Novel mechanism for endothelial dysfunction: Dysregulation of dimethylarginine dimethylaminohydrolase
-
A. Ito, P.S. Tsao, S. Adimoolam, M. Kimoto, T. Ogawa, and J.P. Cooke Novel mechanism for endothelial dysfunction: dysregulation of dimethylarginine dimethylaminohydrolase Circulation 99 1999 3092 3095 (Pubitemid 29289071)
-
(1999)
Circulation
, vol.99
, Issue.24
, pp. 3092-3095
-
-
Ito, A.1
Tsao, P.S.2
Adimoolam, S.3
Kimoto, M.4
Ogawa, T.5
Cooke, J.P.6
-
168
-
-
26044460259
-
G- dimethyl-L-arginine in 500 subjects
-
DOI 10.1111/j.1365-2362.2005.01561.x
-
F. Schulze, R. Maas, R. Freese, E. Schwedhelm, E. Silberhorn, and R.H. Boger Determination of a reference value for N(G), N(G)-dimethyl-L-arginine in 500 subjects Eur. J. Clin. Invest. 35 2005 622 626 (Pubitemid 41406726)
-
(2005)
European Journal of Clinical Investigation
, vol.35
, Issue.10
, pp. 622-626
-
-
Schulze, F.1
Maas, R.2
Freese, R.3
Schwedhelm, E.4
Silberhorn, E.5
Boger, R.H.6
-
169
-
-
31344435701
-
Asymmetric dimethylarginine (ADMA) accelerates cell senescence
-
S.M. Bode-Boger, F. Scalera, and J. Martens-Lobenhoffer Asymmetric dimethylarginine (ADMA) accelerates cell senescence Vasc. Med 10 Suppl. 1 2005 S65 S71
-
(2005)
Vasc. Med
, vol.10
, Issue.SUPPL. 1
-
-
Bode-Boger, S.M.1
Scalera, F.2
Martens-Lobenhoffer, J.3
-
170
-
-
80052266526
-
Cross talk between mitochondria and NADPH oxidases
-
S. Dikalov Cross talk between mitochondria and NADPH oxidases Free Radic. Biol. Med. 51 2011 1289 1301
-
(2011)
Free Radic. Biol. Med.
, vol.51
, pp. 1289-1301
-
-
Dikalov, S.1
-
171
-
-
41949104144
-
Molecular mechanisms of angiotensin II-mediated mitochondrial dysfunction: Linking mitochondrial oxidative damage and vascular endothelial dysfunction
-
DOI 10.1161/CIRCRESAHA.107.162800
-
A.K. Doughan, D.G. Harrison, and S.I. Dikalov Molecular mechanisms of angiotensin II-mediated mitochondrial dysfunction: linking mitochondrial oxidative damage and vascular endothelial dysfunction Circ. Res. 102 2008 488 496 (Pubitemid 351651106)
-
(2008)
Circulation Research
, vol.102
, Issue.4
, pp. 488-496
-
-
Doughan, A.K.1
Harrison, D.G.2
Dikalov, S.I.3
-
172
-
-
79551601555
-
Redox regulation of the mitochondrial K(ATP) channel in cardioprotection
-
B.B. Queliconi, A.P. Wojtovich, S.M. Nadtochiy, A.J. Kowaltowski, and P.S. Brookes Redox regulation of the mitochondrial K(ATP) channel in cardioprotection Biochim. Biophys. Acta 1813 2011 1309 1315
-
(2011)
Biochim. Biophys. Acta
, vol.1813
, pp. 1309-1315
-
-
Queliconi, B.B.1
Wojtovich, A.P.2
Nadtochiy, S.M.3
Kowaltowski, A.J.4
Brookes, P.S.5
-
173
-
-
33644801415
-
The direct physiological effects of mitoK(ATP) opening on heart mitochondria
-
A.D. Costa, C.L. Quinlan, A. Andrukhiv, I.C. West, M. Jaburek, and K.D. Garlid The direct physiological effects of mitoK(ATP) opening on heart mitochondria Am. J. Physiol. Heart Circ. Physol 290 2006 H406 H415
-
(2006)
Am. J. Physiol. Heart Circ. Physol
, vol.290
-
-
Costa, A.D.1
Quinlan, C.L.2
Andrukhiv, A.3
West, I.C.4
Jaburek, M.5
Garlid, K.D.6
-
174
-
-
77954698808
-
Therapeutic targeting of mitochondrial superoxide in hypertension
-
A.E. Dikalova, A.T. Bikineyeva, K. Budzyn, R.R. Nazarewicz, L. McCann, W. Lewis, D.G. Harrison, and S.I. Dikalov Therapeutic targeting of mitochondrial superoxide in hypertension Circ. Res. 107 2010 106 116
-
(2010)
Circ. Res.
, vol.107
, pp. 106-116
-
-
Dikalova, A.E.1
Bikineyeva, A.T.2
Budzyn, K.3
Nazarewicz, R.R.4
McCann, L.5
Lewis, W.6
Harrison, D.G.7
Dikalov, S.I.8
-
175
-
-
53449086013
-
Hypoxia activates NADPH oxidase to increase [ROS]i and [Ca2+]i through the mitochondrial ROS-PKCepsilon signaling axis in pulmonary artery smooth muscle cells
-
R. Rathore, Y.M. Zheng, C.F. Niu, Q.H. Liu, A. Korde, Y.S. Ho, and Y.X. Wang Hypoxia activates NADPH oxidase to increase [ROS]i and [Ca2+]i through the mitochondrial ROS-PKCepsilon signaling axis in pulmonary artery smooth muscle cells Free Radic. Biol. Med. 45 2008 1223 1231
-
(2008)
Free Radic. Biol. Med.
, vol.45
, pp. 1223-1231
-
-
Rathore, R.1
Zheng, Y.M.2
Niu, C.F.3
Liu, Q.H.4
Korde, A.5
Ho, Y.S.6
Wang, Y.X.7
-
176
-
-
33746732912
-
2-induced endothelial dysfunction
-
DOI 10.1016/j.freeradbiomed.2006.05.030, PII S0891584906003601
-
2-induced endothelial dysfunction Free Radic. Biol. Med. 41 2006 810 817 (Pubitemid 44163414)
-
(2006)
Free Radical Biology and Medicine
, vol.41
, Issue.5
, pp. 810-817
-
-
Boulden, B.M.1
Widder, J.D.2
Allen, J.C.3
Smith, D.A.4
Al-Baldawi, R.N.5
Harrison, D.G.6
Dikalov, S.I.7
Jo, H.8
Dudley Jr., S.C.9
-
177
-
-
13844266737
-
Changes in tetrahydrobiopterin levels in endothelial cells and adult cardiomyocytes induced by LPS and hydrogen peroxide - A role for GFRP?
-
DOI 10.1016/j.freeradbiomed.2004.11.004
-
S. Kalivendi, K. Hatakeyama, J. Whitsett, E. Konorev, B. Kalyanaraman, and J. Vasquez-Vivar Changes in tetrahydrobiopterin levels in endothelial cells and adult cardiomyocytes induced by LPS and hydrogen peroxide - a role for GFRP? Free Radic. Biol. Med 38 2005 481 491 (Pubitemid 40247438)
-
(2005)
Free Radical Biology and Medicine
, vol.38
, Issue.4
, pp. 481-491
-
-
Kalivendi, S.1
Hatakeyama, K.2
Whitsett, J.3
Konorev, E.4
Kalyanaraman, B.5
Vasquez-Vivar, J.6
-
178
-
-
0031919108
-
Interaction between superoxide anion and nitric oxide in the regulation of vascular endothelial function
-
DOI 10.1038/sj.bjp.0701814
-
D.W. Laight, A.V. Kaw, M.J. Carrier, and E.E. Anggard Interaction between superoxide anion and nitric oxide in the regulation of vascular endothelial function Br. J. Pharmacol. 124 1998 238 244 (Pubitemid 28210065)
-
(1998)
British Journal of Pharmacology
, vol.124
, Issue.1
, pp. 238-244
-
-
Laight, D.W.1
Kaw, A.V.2
Carrier, M.J.3
Anggard, E.E.4
-
179
-
-
3943073829
-
Vascular protection: Superoxide dismutase isoforms in the vessel wall
-
DOI 10.1161/01.ATV.0000133604.20182.cf
-
F.M. Faraci, and S.P. Didion Vascular protection: superoxide dismutase isoforms in the vessel wall Arterioscler. Thromb. Vasc. Biol. 24 2004 1367 1373 (Pubitemid 39050427)
-
(2004)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.24
, Issue.8
, pp. 1367-1373
-
-
Faraci, F.M.1
Didion, S.P.2
-
180
-
-
38849168859
-
Alteration in flow (shear stress)-induced remodelling in rat resistance arteries with aging: Improvement by a treatment with hydralazine
-
DOI 10.1093/cvr/cvm055
-
O. Dumont, F. Pinaud, A.L. Guihot, C. Baufreton, L. Loufrani, and D. Henrion Alteration in flow (shear stress)-induced remodelling in rat resistance arteries with aging: improvement by a treatment with hydralazine Cardiovasc. Res. 77 2008 600 608 (Pubitemid 351197657)
-
(2008)
Cardiovascular Research
, vol.77
, Issue.3
, pp. 600-608
-
-
Dumont, O.1
Pinaud, F.2
Guihot, A.-L.3
Baufreton, C.4
Loufrani, L.5
Henrion, D.6
-
182
-
-
0029848789
-
Extracellular superoxide dismutase: A regulator of nitric oxide bioavailability
-
T.D. Oury, B.J. Day, and J.D. Crapo Extracellular superoxide dismutase: a regulator of nitric oxide bioavailability Lab. Invest. 75 1996 617 636 (Pubitemid 26392794)
-
(1996)
Laboratory Investigation
, vol.75
, Issue.5
, pp. 617-636
-
-
Oury, T.D.1
Day, B.J.2
Crapo, J.D.3
-
183
-
-
66949146904
-
Protective effect of extracellular superoxide dismutase on endothelial function during aging
-
D.D. Lund, Y. Chu, J.D. Miller, and D.D. Heistad Protective effect of extracellular superoxide dismutase on endothelial function during aging Am. J. Physiol. Heart Circ. Physol 296 2009 H1920 H1925
-
(2009)
Am. J. Physiol. Heart Circ. Physol
, vol.296
-
-
Lund, D.D.1
Chu, Y.2
Miller, J.D.3
Heistad, D.D.4
-
184
-
-
0141864392
-
Extracellular superoxide dismutase is a major determinant of nitric oxide bioavailability: In vivo and ex vivo evidence from ecSOD-deficient mice
-
DOI 10.1161/01.RES.0000092140.81594.A8
-
O. Jung, S.L. Marklund, H. Geiger, T. Pedrazzini, R. Busse, and R.P. Brandes Extracellular superoxide dismutase is a major determinant of nitric oxide bioavailability: in vivo and ex vivo evidence from ecSOD-deficient mice Circ. Res. 93 2003 622 629 (Pubitemid 37222158)
-
(2003)
Circulation Research
, vol.93
, Issue.7
, pp. 622-629
-
-
Jung, O.1
Marklund, S.L.2
Geiger, H.3
Pedrazzini, T.4
Busse, R.5
Brandes, R.P.6
-
185
-
-
31744439108
-
Impaired plasma nitric oxide availability and extracellular superoxide dismutase activity in healthy humans with advancing age
-
DOI 10.1016/j.lfs.2005.06.037, PII S0024320505009094
-
C. Di Massimo, P. Scarpelli, N. Di Lorenzo, G. Caimi, F. di Orio, and M.G. Ciancarelli Impaired plasma nitric oxide availability and extracellular superoxide dismutase activity in healthy humans with advancing age Life Sci. 78 2006 1163 1167 (Pubitemid 43176709)
-
(2006)
Life Sciences
, vol.78
, Issue.11
, pp. 1163-1167
-
-
Di Massimo, C.1
Scarpelli, P.2
Lorenzo, N.D.3
Caimi, G.4
Orio, F.D.5
Ciancarelli, M.G.T.6
-
186
-
-
81155128684
-
Habitually exercising older men do not demonstrate age-associated vascular endothelial oxidative stress
-
G.L. Pierce, A.J. Donato, T.J. LaRocca, I. Eskurza, A.E. Silver, and D.R. Seals Habitually exercising older men do not demonstrate age-associated vascular endothelial oxidative stress Aging Cell 10 2011 1032 1037
-
(2011)
Aging Cell
, vol.10
, pp. 1032-1037
-
-
Pierce, G.L.1
Donato, A.J.2
Larocca, T.J.3
Eskurza, I.4
Silver, A.E.5
Seals, D.R.6
-
187
-
-
67649840689
-
Regulation of superoxide dismutase genes: Implications in disease
-
L. Miao St, and D.K. Clair Regulation of superoxide dismutase genes: implications in disease Free Radic. Biol. Med. 47 2009 344 356
-
(2009)
Free Radic. Biol. Med.
, vol.47
, pp. 344-356
-
-
Miao St, L.1
Clair, D.K.2
-
188
-
-
84865700769
-
Stress resistance in the naked mole-rat: The bare essentials - A mini-review
-
K.N. Lewis, J. Mele, P.J. Hornsby, and R. Buffenstein Stress resistance in the naked mole-rat: the bare essentials - a mini-review Gerontology 58 2012 453 462
-
(2012)
Gerontology
, vol.58
, pp. 453-462
-
-
Lewis, K.N.1
Mele, J.2
Hornsby, P.J.3
Buffenstein, R.4
-
189
-
-
34548146108
-
Effect of aging, MnSOD deficiency, and genetic background on endothelial function: Evidence for MnSOD haploinsufficiency
-
DOI 10.1161/ATVBAHA.107.146852, PII 0004360520070900000012
-
K.A. Brown, S.P. Didion, J.J. Andresen, and F.M. Faraci Effect of aging, MnSOD deficiency, and genetic background on endothelial function: evidence for MnSOD haploinsufficiency Arterioscler. Thromb. Vasc. Biol. 27 2007 1941 1946 (Pubitemid 47312302)
-
(2007)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.27
, Issue.9
, pp. 1941-1946
-
-
Brown, K.A.1
Didion, S.P.2
Andresen, J.J.3
Faraci, F.M.4
-
190
-
-
71549137764
-
Aging decreases expression and activity of glutathione peroxidase-1 in human endothelial progenitor cells
-
T. He, M.J. Joyner, and Z.S. Katusic Aging decreases expression and activity of glutathione peroxidase-1 in human endothelial progenitor cells Microvasc. Res. 78 2009 447 452
-
(2009)
Microvasc. Res.
, vol.78
, pp. 447-452
-
-
He, T.1
Joyner, M.J.2
Katusic, Z.S.3
-
191
-
-
33751094316
-
Heterozygous CuZn superoxide dismutase deficiency produces a vascular phenotype with aging
-
DOI 10.1161/01.HYP.0000247302.20559.3a, PII 0000426820061200000015
-
S.P. Didion, D.A. Kinzenbaw, L.I. Schrader, and F.M. Faraci Heterozygous CuZn superoxide dismutase deficiency produces a vascular phenotype with aging Hypertension 48 2006 1072 1079 (Pubitemid 44772710)
-
(2006)
Hypertension
, vol.48
, Issue.6
, pp. 1072-1079
-
-
Didion, S.P.1
Kinzenbaw, D.A.2
Schrader, L.I.3
Faraci, F.M.4
-
192
-
-
84862855317
-
Evidence of increased oxidative stress in aged mesenteric lymphatic vessels
-
S. Thangaswamy, E.A. Bridenbaugh, and A.A. Gashev Evidence of increased oxidative stress in aged mesenteric lymphatic vessels Lymphat. Res. Biol 10 2012 53 62
-
(2012)
Lymphat. Res. Biol
, vol.10
, pp. 53-62
-
-
Thangaswamy, S.1
Bridenbaugh, E.A.2
Gashev, A.A.3
-
193
-
-
33845619005
-
Shear stress stabilizes NF-E2-related factor 2 and induces antioxidant genes in endothelial cells: Role of reactive oxygen/nitrogen species
-
DOI 10.1016/j.freeradbiomed.2006.10.043, PII S0891584906006745
-
E. Warabi, W. Takabe, T. Minami, K. Inoue, K. Itoh, M. Yamamoto, T. Ishii, T. Kodama, and N. Noguchi Shear stress stabilizes NF-E2-related factor 2 and induces antioxidant genes in endothelial cells: role of reactive oxygen/nitrogen species Free Radic. Biol. Med. 42 2007 260 269 (Pubitemid 44959746)
-
(2007)
Free Radical Biology and Medicine
, vol.42
, Issue.2
, pp. 260-269
-
-
Warabi, E.1
Takabe, W.2
Minami, T.3
Inoue, K.4
Itoh, K.5
Yamamoto, M.6
Ishii, T.7
Kodama, T.8
Noguchi, N.9
-
194
-
-
58149352893
-
Activation of NF-E2-related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease
-
M. Xue, Q. Qian, A. Adaikalakoteswari, N. Rabbani, R. Babaei-Jadidi, and P.J. Thornalley Activation of NF-E2-related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease Diabetes 57 2008 2809 2817
-
(2008)
Diabetes
, vol.57
, pp. 2809-2817
-
-
Xue, M.1
Qian, Q.2
Adaikalakoteswari, A.3
Rabbani, N.4
Babaei-Jadidi, R.5
Thornalley, P.J.6
-
195
-
-
78649635403
-
Nrf2, a guardian of healthspan and gatekeeper of species longevity
-
K.N. Lewis, J. Mele, J.D. Hayes, and R. Buffenstein Nrf2, a guardian of healthspan and gatekeeper of species longevity Integr. Comp. Biol. 50 2010 829 843
-
(2010)
Integr. Comp. Biol.
, vol.50
, pp. 829-843
-
-
Lewis, K.N.1
Mele, J.2
Hayes, J.D.3
Buffenstein, R.4
-
196
-
-
80051484050
-
Age-associated vascular oxidative stress, Nrf2 dysfunction, and NF-{kappa}B activation in the nonhuman primate Macaca mulatta
-
Z. Ungvari, L. Bailey-Downs, T. Gautam, D. Sosnowska, M. Wang, R.E. Monticone, R. Telljohann, J.T. Pinto, R. de Cabo, W.E. Sonntag, E.G. Lakatta, and A. Csiszar Age-associated vascular oxidative stress, Nrf2 dysfunction, and NF-{kappa}B activation in the nonhuman primate Macaca mulatta J. Gerontol. A Biol. Sci. Med. Sci 66 2011 866 875
-
(2011)
J. Gerontol. A Biol. Sci. Med. Sci
, vol.66
, pp. 866-875
-
-
Ungvari, Z.1
Bailey-Downs, L.2
Gautam, T.3
Sosnowska, D.4
Wang, M.5
Monticone, R.E.6
Telljohann, R.7
Pinto, J.T.8
De Cabo, R.9
Sonntag, W.E.10
Lakatta, E.G.11
Csiszar, A.12
-
197
-
-
84866346444
-
Disruption of Nrf2 signaling impairs angiogenic capacity of endothelial cells: Implications for microvascular aging
-
M.N. Valcarcel-Ares, T. Gautam, J.P. Warrington, L. Bailey-Downs, D. Sosnowska, R. de Cabo, G. Losonczy, W.E. Sonntag, Z. Ungvari, and A. Csiszar Disruption of Nrf2 signaling impairs angiogenic capacity of endothelial cells: implications for microvascular aging J. Gerontol. A Biol. Sci. Med. Sci 67 2012 821 829
-
(2012)
J. Gerontol. A Biol. Sci. Med. Sci
, vol.67
, pp. 821-829
-
-
Valcarcel-Ares, M.N.1
Gautam, T.2
Warrington, J.P.3
Bailey-Downs, L.4
Sosnowska, D.5
De Cabo, R.6
Losonczy, G.7
Sonntag, W.E.8
Ungvari, Z.9
Csiszar, A.10
-
198
-
-
34548617735
-
Low rates of hydrogen peroxide production by isolated heart mitochondria associate with long maximum lifespan in vertebrate homeotherms
-
DOI 10.1111/j.1474-9726.2007.00312.x
-
A.J. Lambert, H.M. Boysen, J.A. Buckingham, T. Yang, A. Podlutsky, S.N. Austad, T.H. Kunz, R. Buffenstein, and M.D. Brand Low rates of hydrogen peroxide production by isolated heart mitochondria associate with long maximum lifespan in vertebrate homeotherms Aging Cell 6 2007 607 618 (Pubitemid 47400043)
-
(2007)
Aging Cell
, vol.6
, Issue.5
, pp. 607-618
-
-
Lambert, A.J.1
Boysen, H.M.2
Buckingham, J.A.3
Yang, T.4
Podlutsky, A.5
Austad, S.N.6
Kunz, T.H.7
Buffenstein, R.8
Brand, M.D.9
-
200
-
-
40849118472
-
Direct Inhibition of the Longevity-Promoting Factor SKN-1 by Insulin-like Signaling in C elegans
-
DOI 10.1016/j.cell.2008.01.030, PII S009286740800130X
-
J.M. Tullet, M. Hertweck, J.H. An, J. Baker, J.Y. Hwang, S. Liu, R.P. Oliveira, R. Baumeister, and T.K. Blackwell Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans Cell 132 2008 1025 1038 (Pubitemid 351391953)
-
(2008)
Cell
, vol.132
, Issue.6
, pp. 1025-1038
-
-
Tullet, J.M.A.1
Hertweck, M.2
An, J.H.3
Baker, J.4
Hwang, J.Y.5
Liu, S.6
Oliveira, R.P.7
Baumeister, R.8
Blackwell, T.K.9
-
202
-
-
33845388290
-
2 production, and vascular oxidative stress resistance between the longest-living rodent, the naked mole rat, and mice
-
2 production, and vascular oxidative stress resistance between the longest-living rodent, the naked mole rat, and mice. Am. J. Physiol. Heart Circ. Physol. 291 2006 H2698 H2704
-
(2006)
Am. J. Physiol. Heart Circ. Physol.
, vol.291
-
-
Labinskyy, N.1
Csiszar, A.2
Orosz, Z.3
Smith, K.4
Rivera, A.5
Buffenstein, R.6
Ungvari, Z.7
-
203
-
-
0033922968
-
Aging exacerbates hydrogen peroxide-induced alteration of vascular reactivity in rats
-
S. Tanguy, F. Boucher, M.C. Toufektsian, S. Besse, and J. de Leiris Aging exacerbates hydrogen peroxide-induced alteration of vascular reactivity in rats Antioxid. Redox Signal. 2 2000 363 368 (Pubitemid 30445947)
-
(2000)
Antioxidants and Redox Signaling
, vol.2
, Issue.2
, pp. 363-368
-
-
Tanguy, S.1
Boucher, F.2
Toufektsian, M.-C.3
Besse, S.4
De Leiris, J.5
-
204
-
-
0036266110
-
Attenuated HSP70 response in skeletal muscle of aged rats following contractile activity
-
DOI 10.1002/mus.10094
-
A. Vasilaki, M.J. Jackson, and A. McArdle Attenuated HSP70 response in skeletal muscle of aged rats following contractile activity Muscle Nerve 25 2002 902 905 (Pubitemid 34579001)
-
(2002)
Muscle and Nerve
, vol.25
, Issue.6
, pp. 902-905
-
-
Vasilaki, A.1
Jackson, M.J.2
McArdle, A.3
-
205
-
-
33750161128
-
Adaptive responses of mouse skeletal muscle to contractile activity: The effect of age
-
DOI 10.1016/j.mad.2006.08.004, PII S004763740600193X
-
A. Vasilaki, F. McArdle, L.M. Iwanejko, and A. McArdle Adaptive responses of mouse skeletal muscle to contractile activity: the effect of age Mech. Ageing Dev. 127 2006 830 839 (Pubitemid 44602139)
-
(2006)
Mechanisms of Ageing and Development
, vol.127
, Issue.11
, pp. 830-839
-
-
Vasilaki, A.1
McArdle, F.2
Iwanejko, L.M.3
McArdle, A.4
-
206
-
-
14644444464
-
Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle
-
DOI 10.1096/fj.04-2640fje
-
D. Cuthbertson, K. Smith, J. Babraj, G. Leese, T. Waddell, P. Atherton, H. Wackerhage, P.M. Taylor, and M.J. Rennie Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle FASEB J 19 2005 422 424 (Pubitemid 40316537)
-
(2005)
FASEB Journal
, vol.19
, Issue.3
, pp. 422-424
-
-
Cuthbertson, D.1
Smith, K.2
Babraj, J.3
Leese, G.4
Waddell, T.5
Atherton, P.6
Wackerhage, H.7
Taylor, P.M.8
Rennie, M.J.9
-
207
-
-
79955425933
-
Age-related changes in skeletal muscle reactive oxygen species generation and adaptive responses to reactive oxygen species
-
M.J. Jackson, and A. McArdle Age-related changes in skeletal muscle reactive oxygen species generation and adaptive responses to reactive oxygen species J. Physiol 589 2011 2139 2145
-
(2011)
J. Physiol
, vol.589
, pp. 2139-2145
-
-
Jackson, M.J.1
McArdle, A.2
-
208
-
-
78249273621
-
The age-related failure of adaptive responses to contractile activity in skeletal muscle is mimicked in young mice by deletion of Cu,Zn superoxide dismutase
-
A. Vasilaki, J.H. van der Meulen, L. Larkin, D.C. Harrison, T. Pearson, H. Van Remmen, A. Richardson, S.V. Brooks, M.J. Jackson, and A. McArdle The age-related failure of adaptive responses to contractile activity in skeletal muscle is mimicked in young mice by deletion of Cu,Zn superoxide dismutase Aging Cell 9 2010 979 990
-
(2010)
Aging Cell
, vol.9
, pp. 979-990
-
-
Vasilaki, A.1
Van Der Meulen, J.H.2
Larkin, L.3
Harrison, D.C.4
Pearson, T.5
Van Remmen, H.6
Richardson, A.7
Brooks, S.V.8
Jackson, M.J.9
McArdle, A.10
-
209
-
-
30544444397
-
Amadori adducts activate nuclear factor-κB-related proinflammatory genes in cultured human peritoneal mesothelial cells
-
DOI 10.1038/sj.bjp.0706309
-
J. Nevado, C. Peiro, S. Vallejo, M. El-Assar, N. Lafuente, N. Matesanz, V. Azcutia, E. Cercas, C.F. Sanchez-Ferrer, and L. Rodriguez-Manas Amadori adducts activate nuclear factor-kappaB-related proinflammatory genes in cultured human peritoneal mesothelial cells Br. J. Pharmacol. 146 2005 268 279 (Pubitemid 43079967)
-
(2005)
British Journal of Pharmacology
, vol.146
, Issue.2
, pp. 268-279
-
-
Nevado, J.1
Peiro, C.2
Vallejo, S.3
El-Assar, M.4
Lafuente, N.5
Matesanz, N.6
Azcutia, V.7
Cercas, E.8
Sanchez-Ferrer, C.F.9
Rodriguez-Manas, L.10
-
210
-
-
33845605922
-
Pro-inflammatory effects of early non-enzymatic glycated proteins in human mesothelial cells vary with cell donor's age
-
DOI 10.1038/sj.bjp.0706864, PII 0706864
-
L. Rodriguez-Manas, C. Sanchez-Rodriguez, S. Vallejo, M. El-Assar, C. Peiro, V. Azcutia, N. Matesanz, C.F. Sanchez-Ferrer, and J. Nevado Pro-inflammatory effects of early non-enzymatic glycated proteins in human mesothelial cells vary with cell donor's age Br. J. Pharmacol. 149 2006 979 987 (Pubitemid 44950801)
-
(2006)
British Journal of Pharmacology
, vol.149
, Issue.8
, pp. 979-987
-
-
Rodriguez-Manas, L.1
Sanchez-Rodriguez, C.2
Vallejo, S.3
El-Assar, M.4
Peiro, C.5
Azcutia, V.6
Matesanz, N.7
Sanchez-Ferrer, C.F.8
Nevado, J.9
-
211
-
-
33644644429
-
Changes in the human peritoneal mesothelial cells during aging
-
DOI 10.1038/sj.ki.5000082, PII 5000082
-
J. Nevado, S. Vallejo, M. El-Assar, C. Peiro, C.F. Sanchez-Ferrer, and L. Rodriguez-Manas Changes in the human peritoneal mesothelial cells during aging Kidney Int. 69 2006 313 322 (Pubitemid 43323082)
-
(2006)
Kidney International
, vol.69
, Issue.2
, pp. 313-322
-
-
Nevado, J.1
Vallejo, S.2
El-Assar, M.3
Peiro, C.4
Sanchez-Ferrer, C.F.5
Rodriguez-Manas, L.6
-
212
-
-
1842555356
-
Modulatory properties of various natural chemopreventive agents on the activation of NF-κB signaling pathway
-
DOI 10.1023/B:PHAM.0000022413.43212.cf
-
W.S. Jeong, I.W. Kim, R. Hu, and A.N. Kong Modulatory properties of various natural chemopreventive agents on the activation of NF-kappaB signaling pathway Pharm. Res. 21 2004 661 670 (Pubitemid 38457289)
-
(2004)
Pharmaceutical Research
, vol.21
, Issue.4
, pp. 661-670
-
-
Jeong, W.-S.1
Kim, I.-W.2
Hu, R.3
Kong, A.-N.T.4
-
213
-
-
22744440329
-
Suppression of NF-κB and NF-κB-regulated gene expression by sulforaphane and PEITC through IκBα, IKK pathway in human prostate cancer PC-3 cells
-
DOI 10.1038/sj.onc.1208656
-
C. Xu, G. Shen, C. Chen, C. Gelinas, and A.N. Kong Suppression of NF-kappaB and NF-kappaB-regulated gene expression by sulforaphane and PEITC through IkappaBalpha, IKK pathway in human prostate cancer PC-3 cells Oncogene 24 2005 4486 4495 (Pubitemid 41032612)
-
(2005)
Oncogene
, vol.24
, Issue.28
, pp. 4486-4495
-
-
Xu, C.1
Shen, G.2
Chen, C.3
Gelinas, C.4
Kong, A.-N.T.5
-
214
-
-
41949141296
-
NF-kappaB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK
-
G.H. Liu, J. Qu, and X. Shen NF-kappaB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK Biochim. Biophys. Acta 1783 2008 713 727
-
(2008)
Biochim. Biophys. Acta
, vol.1783
, pp. 713-727
-
-
Liu, G.H.1
Qu, J.2
Shen, X.3
-
215
-
-
74949135703
-
Exercise-induced brachial artery vasodilation: Effects of antioxidants and exercise training in elderly men
-
A.J. Donato, A. Uberoi, D.M. Bailey, D.W. Wray, and R.S. Richardson Exercise-induced brachial artery vasodilation: effects of antioxidants and exercise training in elderly men Am. J. Physiol. Heart Circ. Physol 298 2010 H671 H678
-
(2010)
Am. J. Physiol. Heart Circ. Physol
, vol.298
-
-
Donato, A.J.1
Uberoi, A.2
Bailey, D.M.3
Wray, D.W.4
Richardson, R.S.5
-
216
-
-
84878613877
-
Age and exercise training alter signaling through reactive oxygen species in the endothelium of skeletal muscle arterioles
-
A.L. Sindler, R. Reyes, B. Chen, P. Ghosh, A.N. Gurovich, L.S. Kang, A.J. Cardounel, M.D. Delp, and J.M. Muller-Delp Age and exercise training alter signaling through reactive oxygen species in the endothelium of skeletal muscle arterioles J. Appl. Physiol. 114 2013 681 693
-
(2013)
J. Appl. Physiol.
, vol.114
, pp. 681-693
-
-
Sindler, A.L.1
Reyes, R.2
Chen, B.3
Ghosh, P.4
Gurovich, A.N.5
Kang, L.S.6
Cardounel, A.J.7
Delp, M.D.8
Muller-Delp, J.M.9
-
217
-
-
84870291477
-
Moderate superoxide production is an early promoter of mitochondrial biogenesis in differentiating N2a neuroblastoma cells
-
T. Valero, G. Moschopoulou, L. Mayor-Lopez, and S. Kintzios Moderate superoxide production is an early promoter of mitochondrial biogenesis in differentiating N2a neuroblastoma cells Neurochem. Int. 61 2012 1333 1343
-
(2012)
Neurochem. Int.
, vol.61
, pp. 1333-1343
-
-
Valero, T.1
Moschopoulou, G.2
Mayor-Lopez, L.3
Kintzios, S.4
-
218
-
-
83155181828
-
Apnea stimulates the adaptive response to oxidative stress in elephant seal pups
-
J.P. Vazquez-Medina, T. Zenteno-Savin, M.S. Tift, H.J. Forman, D.E. Crocker, and R.M. Ortiz Apnea stimulates the adaptive response to oxidative stress in elephant seal pups J. Exp. Biol. 214 2011 4193 4200
-
(2011)
J. Exp. Biol.
, vol.214
, pp. 4193-4200
-
-
Vazquez-Medina, J.P.1
Zenteno-Savin, T.2
Tift, M.S.3
Forman, H.J.4
Crocker, D.E.5
Ortiz, R.M.6
-
219
-
-
44349140050
-
Hyperoxia exposure induced hormesis decreases mitochondrial superoxide radical levels via Ins/IGF-1 signaling pathway in a long-lived age-1 mutant of Caenorhabditis elegans
-
DOI 10.1269/jrr.07043
-
S. Yanase, and N. Ishii Hyperoxia exposure induced hormesis decreases mitochondrial superoxide radical levels via Ins/IGF-1 signaling pathway in a long-lived age-1 mutant of Caenorhabditis elegans J. Radiat. Res 49 2008 211 218 (Pubitemid 351744273)
-
(2008)
Journal of Radiation Research
, vol.49
, Issue.3
, pp. 211-218
-
-
Yanase, S.1
Ishii, N.2
-
220
-
-
55449136486
-
Inflammation and endothelial dysfunction during aging: Role of NF-kappaB
-
A. Csiszar, M. Wang, E.G. Lakatta, and Z. Ungvari Inflammation and endothelial dysfunction during aging: role of NF-kappaB J. Appl. Physiol. 105 2008 1333 1341
-
(2008)
J. Appl. Physiol.
, vol.105
, pp. 1333-1341
-
-
Csiszar, A.1
Wang, M.2
Lakatta, E.G.3
Ungvari, Z.4
-
221
-
-
39649085837
-
Inflammaging as a major characteristic of old people: Can it be prevented or cured?
-
C. Franceschi Inflammaging as a major characteristic of old people: can it be prevented or cured? Nutr. Rev 65 2007 S173 176
-
(2007)
Nutr. Rev
, vol.65
, pp. 173-176
-
-
Franceschi, C.1
-
222
-
-
33646685457
-
The molecular inflammatory process in aging
-
DOI 10.1089/ars.2006.8.572
-
H.Y. Chung, B. Sung, K.J. Jung, Y. Zou, and B.P. Yu The molecular inflammatory process in aging Antioxid. Redox Signal. 8 2006 572 581 (Pubitemid 43741326)
-
(2006)
Antioxidants and Redox Signaling
, vol.8
, Issue.3-4
, pp. 572-581
-
-
Chung, H.Y.1
Sung, B.2
Jung, K.J.3
Zou, Y.4
Yu, B.P.5
-
223
-
-
79953031609
-
Independent and additive effects of cytokine patterns and the metabolic syndrome on arterial aging in the SardiNIA study
-
A. Scuteri, M. Orru, C. Morrell, M.G. Piras, D. Taub, D. Schlessinger, M. Uda, and E.G. Lakatta Independent and additive effects of cytokine patterns and the metabolic syndrome on arterial aging in the SardiNIA study Atherosclerosis 215 2011 459 464
-
(2011)
Atherosclerosis
, vol.215
, pp. 459-464
-
-
Scuteri, A.1
Orru, M.2
Morrell, C.3
Piras, M.G.4
Taub, D.5
Schlessinger, D.6
Uda, M.7
Lakatta, E.G.8
-
224
-
-
15244348518
-
The origins of age-related proinflammatory state
-
DOI 10.1182/blood-2004-07-2599
-
L. Ferrucci, A. Corsi, F. Lauretani, S. Bandinelli, B. Bartali, D.D. Taub, J.M. Guralnik, and D.L. Longo The origins of age-related proinflammatory state Blood 105 2005 2294 2299 (Pubitemid 40387022)
-
(2005)
Blood
, vol.105
, Issue.6
, pp. 2294-2299
-
-
Ferrucci, L.1
Corsi, A.2
Lauretani, F.3
Bandinelli, S.4
Bartali, B.5
Taub, D.D.6
Guralnik, J.M.7
Longo, D.L.8
-
225
-
-
38049004876
-
Age-related increases in circulating inflammatory markers in men are independent of BMI, blood pressure and blood lipid concentrations
-
E.A. Miles, D. Rees, T. Banerjee, R. Cazzola, S. Lewis, R. Wood, R. Oates, A. Tallant, B. Cestaro, P. Yaqoob, K.W. Wahle, and P.C. Calder Age-related increases in circulating inflammatory markers in men are independent of BMI, blood pressure and blood lipid concentrations Atherosclerosis 196 2008 298 305
-
(2008)
Atherosclerosis
, vol.196
, pp. 298-305
-
-
Miles, E.A.1
Rees, D.2
Banerjee, T.3
Cazzola, R.4
Lewis, S.5
Wood, R.6
Oates, R.7
Tallant, A.8
Cestaro, B.9
Yaqoob, P.10
Wahle, K.W.11
Calder, P.C.12
-
226
-
-
12344251549
-
Vascular inflammation in aging
-
DOI 10.1007/s00059-004-2625-x
-
Z. Ungvari, A. Csiszar, and G. Kaley Vascular inflammation in aging Herz 29 2004 733 740 (Pubitemid 40125707)
-
(2004)
Herz
, vol.29
, Issue.8
, pp. 733-740
-
-
Ungvari, Z.1
Csiszar, A.2
Kaley, G.3
-
227
-
-
84861025869
-
Oxidative damage, platelet activation, and inflammation to predict mobility disability and mortality in older persons: Results from the health aging and body composition study
-
M. Cesari, S.B. Kritchevsky, B. Nicklas, A.M. Kanaya, P. Patrignani, S. Tacconelli, G.J. Tranah, G. Tognoni, T.B. Harris, R.A. Incalzi, A.B. Newman, and M. Pahor Oxidative damage, platelet activation, and inflammation to predict mobility disability and mortality in older persons: results from the health aging and body composition study J. Gerontol. A Biol. Sci. Med. Sci 67 2012 671 676
-
(2012)
J. Gerontol. A Biol. Sci. Med. Sci
, vol.67
, pp. 671-676
-
-
Cesari, M.1
Kritchevsky, S.B.2
Nicklas, B.3
Kanaya, A.M.4
Patrignani, P.5
Tacconelli, S.6
Tranah, G.J.7
Tognoni, G.8
Harris, T.B.9
Incalzi, R.A.10
Newman, A.B.11
Pahor, M.12
-
228
-
-
4043073559
-
C-reactive protein and arterial stiffness in older adults: The Rotterdam Study
-
DOI 10.1016/j.atherosclerosis.2004.04.014, PII S002191500400228X
-
F.U. Mattace-Raso, T.J. van der Cammen, I.M. van der Meer, M.A. Schalekamp, R. Asmar, A. Hofman, and J.C. Witteman C-reactive protein and arterial stiffness in older adults: the Rotterdam Study Atherosclerosis 176 2004 111 116 (Pubitemid 39078652)
-
(2004)
Atherosclerosis
, vol.176
, Issue.1
, pp. 111-116
-
-
Mattace-Raso, F.U.S.1
Van Der Cammen, T.J.M.2
Van Der Meer, I.M.3
Schalekamp, M.A.D.H.4
Asmar, R.5
Hofman, A.6
Witteman, J.C.M.7
-
229
-
-
36448992617
-
C-reactive protein and aortic stiffness and wave reflection in middle-aged and elderly men from the community
-
DOI 10.1038/sj.jhh.1002255, PII 1002255
-
H.R. Nakhai-Pour, D.E. Grobbee, M.L. Bots, M. Muller, and Y.T. van der Schouw C-reactive protein and aortic stiffness and wave reflection in middle-aged and elderly men from the community J. Hum. Hypertens. 21 2007 949 955 (Pubitemid 350162703)
-
(2007)
Journal of Human Hypertension
, vol.21
, Issue.12
, pp. 949-955
-
-
Nakhai-Pour, H.R.1
Grobbee, D.E.2
Bots, M.L.3
Muller, M.4
Van Der Schouw, Y.T.5
-
230
-
-
34250816941
-
Proinflammatory profile within the grossly normal aged human aortic wall
-
DOI 10.1161/HYPERTENSIONAHA.107.089409
-
M. Wang, J. Zhang, L.Q. Jiang, G. Spinetti, G. Pintus, R. Monticone, F.D. Kolodgie, R. Virmani, and E.G. Lakatta Proinflammatory profile within the grossly normal aged human aortic wall Hypertension 50 2007 219 227 (Pubitemid 46986044)
-
(2007)
Hypertension
, vol.50
, Issue.1
, pp. 219-227
-
-
Wang, M.1
Zhang, J.2
Jiang, L.-Q.3
Spinetti, G.4
Pintus, G.5
Monticone, R.6
Kolodgie, F.D.7
Virmani, R.8
Lakatta, E.G.9
-
231
-
-
83655163745
-
Aging enhances the basal production of IL-6 and CCL2 in vascular smooth muscle cells
-
Y. Song, H. Shen, D. Schenten, P. Shan, P.J. Lee, and D.R. Goldstein Aging enhances the basal production of IL-6 and CCL2 in vascular smooth muscle cells Arterioscler. Thromb. Vasc. Biol. 32 2012 103 109
-
(2012)
Arterioscler. Thromb. Vasc. Biol.
, vol.32
, pp. 103-109
-
-
Song, Y.1
Shen, H.2
Schenten, D.3
Shan, P.4
Lee, P.J.5
Goldstein, D.R.6
-
232
-
-
57949087452
-
Molecular inflammation: Underpinnings of aging and age-related diseases
-
H.Y. Chung, M. Cesari, S. Anton, E. Marzetti, S. Giovannini, A.Y. Seo, C. Carter, B.P. Yu, and C. Leeuwenburgh Molecular inflammation: underpinnings of aging and age-related diseases Ageing Res. Rev. 8 2009 18 30
-
(2009)
Ageing Res. Rev.
, vol.8
, pp. 18-30
-
-
Chung, H.Y.1
Cesari, M.2
Anton, S.3
Marzetti, E.4
Giovannini, S.5
Seo, A.Y.6
Carter, C.7
Yu, B.P.8
Leeuwenburgh, C.9
-
233
-
-
0033392430
-
Augmented expression of inducible NO synthase in vascular smooth muscle cells during aging is associated with enhanced NF-κB activation
-
Z.Q. Yan, A. Sirsjo, M.L. Bochaton-Piallat, G. Gabbiani, and G.K. Hansson Augmented expression of inducible NO synthase in vascular smooth muscle cells during aging is associated with enhanced NF-kappaB activation Arterioscler. Thromb. Vasc. Biol. 19 1999 2854 2862 (Pubitemid 30029810)
-
(1999)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.19
, Issue.12
, pp. 2854-2862
-
-
Yan, Z.-Q.1
Sirsjo, A.2
Bochaton-Piallat, M.-L.3
Gabbiani, G.4
Hansson, G.K.5
-
234
-
-
0031906154
-
Overexpression of inducible nitric oxide synthase by neointimal smooth muscle cells
-
Z. Yan, and G.K. Hansson Overexpression of inducible nitric oxide synthase by neointimal smooth muscle cells Circ. Res. 82 1998 21 29 (Pubitemid 28074015)
-
(1998)
Circulation Research
, vol.82
, Issue.1
, pp. 21-29
-
-
Yan, Z.-Q.1
Hansson, G.K.2
-
235
-
-
33745223031
-
Deficiency of inducible NO synthase reduces advanced but not early atherosclerosis in apolipoprotein E-deficient mice
-
T. Miyoshi, Y. Li, D.M. Shih, X. Wang, V.E. Laubach, A.H. Matsumoto, G.A. Helm, A.J. Lusis, and W. Shi Deficiency of inducible NO synthase reduces advanced but not early atherosclerosis in apolipoprotein E-deficient mice Life Sci. 79 2006 525 531
-
(2006)
Life Sci.
, vol.79
, pp. 525-531
-
-
Miyoshi, T.1
Li, Y.2
Shih, D.M.3
Wang, X.4
Laubach, V.E.5
Matsumoto, A.H.6
Helm, G.A.7
Lusis, A.J.8
Shi, W.9
-
236
-
-
1842509760
-
Proinflammatory phenotype of coronary arteries promotes endothelial apoptosis in aging
-
DOI 10.1152/physiolgenomics.00136.2003
-
A. Csiszar, Z. Ungvari, A. Koller, J.G. Edwards, and G. Kaley Proinflammatory phenotype of coronary arteries promotes endothelial apoptosis in aging Physiol. Genomics 17 2004 21 30 (Pubitemid 38924147)
-
(2004)
Physiological Genomics
, vol.17
, pp. 21-30
-
-
Csiszar, A.1
Ungvari, Z.2
Koller, A.3
Edwards, J.G.4
Kaley, G.5
-
237
-
-
0037339694
-
Increased superoxide production in coronary arteries in hyperhomocysteinemia: Role of tumor necrosis factor-α, NAD(P)H oxidase, and inducible nitric oxide synthase
-
DOI 10.1161/01.ATV.0000061735.85377.40
-
Z. Ungvari, A. Csiszar, J.G. Edwards, P.M. Kaminski, M.S. Wolin, G. Kaley, and A. Koller Increased superoxide production in coronary arteries in hyperhomocysteinemia: role of tumor necrosis factor-alpha, NAD(P)H oxidase, and inducible nitric oxide synthase Arterioscler. Thromb. Vasc. Biol. 23 2003 418 424 (Pubitemid 36337217)
-
(2003)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.23
, Issue.3
, pp. 418-424
-
-
Ungvari, Z.1
Csiszar, A.2
Edwards, J.G.3
Kaminski, P.M.4
Wolin, M.S.5
Kaley, G.6
Koller, A.7
-
238
-
-
13944274907
-
Cytokines and vascular reactivity in resistance arteries
-
E. Vila, and M. Salaices Cytokines and vascular reactivity in resistance arteries Am. J. Physiol. Heart Circ. Physol 288 2005 H1016 H1021
-
(2005)
Am. J. Physiol. Heart Circ. Physol
, vol.288
-
-
Vila, E.1
Salaices, M.2
-
239
-
-
48249091745
-
Hyperglycemia-induced reactive oxygen species toxicity to endothelial cells is dependent on paracrine mediators
-
J.V. Busik, S. Mohr, and M.B. Grant Hyperglycemia-induced reactive oxygen species toxicity to endothelial cells is dependent on paracrine mediators Diabetes 57 2008 1952 1965
-
(2008)
Diabetes
, vol.57
, pp. 1952-1965
-
-
Busik, J.V.1
Mohr, S.2
Grant, M.B.3
-
240
-
-
33645734924
-
Age-associated impairment in vasorelaxation to fluid shear stress in the female vasculature is improved by TNF-alpha antagonism
-
I.A. Arenas, Y. Xu, and S.T. Davidge Age-associated impairment in vasorelaxation to fluid shear stress in the female vasculature is improved by TNF-alpha antagonism Am. J. Physiol. Heart Circ. Physol 290 2006 H1259 H1263
-
(2006)
Am. J. Physiol. Heart Circ. Physol
, vol.290
-
-
Arenas, I.A.1
Xu, Y.2
Davidge, S.T.3
-
241
-
-
33847032609
-
Vasculoprotective effects of anti-tumor necrosis factor-α treatment in aging
-
DOI 10.2353/ajpath.2007.060708
-
A. Csiszar, N. Labinskyy, K. Smith, A. Rivera, Z. Orosz, and Z. Ungvari Vasculoprotective effects of anti-tumor necrosis factor-alpha treatment in aging Am. J. Pathol. 170 2007 388 398 (Pubitemid 47339216)
-
(2007)
American Journal of Pathology
, vol.170
, Issue.1
, pp. 388-398
-
-
Csiszar, A.1
Labinskyy, N.2
Smith, K.3
Rivera, A.4
Orosz, Z.5
Ungvari, Z.6
-
242
-
-
74949106594
-
Vascular endothelial function is related to white blood cell count and myeloperoxidase among healthy middle-aged and older adults
-
A.E. Walker, S.M. Seibert, A.J. Donato, G.L. Pierce, and D.R. Seals Vascular endothelial function is related to white blood cell count and myeloperoxidase among healthy middle-aged and older adults Hypertension 55 2010 363 369
-
(2010)
Hypertension
, vol.55
, pp. 363-369
-
-
Walker, A.E.1
Seibert, S.M.2
Donato, A.J.3
Pierce, G.L.4
Seals, D.R.5
-
243
-
-
33847042684
-
Interleukin-1beta increases expression and activity of matrix metalloproteinase-2 in cardiac microvascular endothelial cells: Role of PKCalpha/beta1 and MAPKs
-
D.J. Mountain, M. Singh, B. Menon, and K. Singh Interleukin-1beta increases expression and activity of matrix metalloproteinase-2 in cardiac microvascular endothelial cells: role of PKCalpha/beta1 and MAPKs Am. J. Physiol. Cell Physiol 292 2007 C867 C875
-
(2007)
Am. J. Physiol. Cell Physiol
, vol.292
-
-
Mountain, D.J.1
Singh, M.2
Menon, B.3
Singh, K.4
-
244
-
-
33846820228
-
Phosphatidic acid as a regulator of matrix metalloproteinase-9 expression via the TNF-alpha signaling pathway
-
J.G. Lee, S.H. Lee, D.W. Park, Y.S. Bae, S.S. Yun, J.R. Kim, and S.H. Baek Phosphatidic acid as a regulator of matrix metalloproteinase-9 expression via the TNF-alpha signaling pathway FEBS Lett. 581 2007 787 793
-
(2007)
FEBS Lett.
, vol.581
, pp. 787-793
-
-
Lee, J.G.1
Lee, S.H.2
Park, D.W.3
Bae, Y.S.4
Yun, S.S.5
Kim, J.R.6
Baek, S.H.7
-
245
-
-
79951566579
-
A local proinflammatory signalling loop facilitates adverse age-associated arterial remodeling
-
M. Wang, G. Spinetti, R.E. Monticone, J. Zhang, J. Wu, L. Jiang, B. Khazan, R. Telljohann, and E.G. Lakatta A local proinflammatory signalling loop facilitates adverse age-associated arterial remodeling PLoS One 6 2011 e16653
-
(2011)
PLoS One
, vol.6
, pp. 16653
-
-
Wang, M.1
Spinetti, G.2
Monticone, R.E.3
Zhang, J.4
Wu, J.5
Jiang, L.6
Khazan, B.7
Telljohann, R.8
Lakatta, E.G.9
-
246
-
-
38849199203
-
Shared principles in NF-kappaB signaling
-
M.S. Hayden, and S. Ghosh Shared principles in NF-kappaB signaling Cell 132 2008 344 362
-
(2008)
Cell
, vol.132
, pp. 344-362
-
-
Hayden, M.S.1
Ghosh, S.2
-
247
-
-
33750435582
-
NF-kappaB and the immune response
-
M.S. Hayden, A.P. West, and S. Ghosh NF-kappaB and the immune response Oncogene 25 2006 6758 6780
-
(2006)
Oncogene
, vol.25
, pp. 6758-6780
-
-
Hayden, M.S.1
West, A.P.2
Ghosh, S.3
-
248
-
-
80855165243
-
Deciphering the role of nuclear factor-kappaB in cellular senescence
-
S. Vaughan, and P.S. Jat Deciphering the role of nuclear factor-kappaB in cellular senescence Aging (Albany NY) 3 2011 913 919
-
(2011)
Aging (Albany NY)
, vol.3
, pp. 913-919
-
-
Vaughan, S.1
Jat, P.S.2
-
249
-
-
0029834145
-
Changes associated with aging and replicative senescence in the regulation of transcription factor nuclear factor-κB
-
M. Helenius, M. Hanninen, S.K. Lehtinen, and A. Salminen Changes associated with aging and replicative senescence in the regulation of transcription factor nuclear factor-kappa B Biochem. J 318 Pt 2 1996 603 608 (Pubitemid 26305964)
-
(1996)
Biochemical Journal
, vol.318
, Issue.2
, pp. 603-608
-
-
Helenius, M.1
Hanninen, M.2
Lehtinen, S.K.3
Salminen, A.4
-
250
-
-
0030960606
-
Age-related changes in the regulation of transcription factor NF-κB in rat brain
-
DOI 10.1016/S0304-3940(97)00190-0, PII S0304394097001900
-
P. Korhonen, M. Helenius, and A. Salminen Age-related changes in the regulation of transcription factor NF-kappa B in rat brain Neurosci. Lett 225 1997 61 64 (Pubitemid 27154218)
-
(1997)
Neuroscience Letters
, vol.225
, Issue.1
, pp. 61-64
-
-
Korhonen, P.1
Helenius, M.2
Salminen, A.3
-
251
-
-
31344434396
-
The ubiquitin-proteasome system at the crossroads of stress-response and ageing pathways: A handle for skin care?
-
DOI 10.1016/j.arr.2005.09.002, PII S1568163705000486
-
F. Bregegere, Y. Milner, and B. Friguet The ubiquitin-proteasome system at the crossroads of stress-response and ageing pathways: a handle for skin care? Ageing Res. Rev 5 2006 60 90 (Pubitemid 43139668)
-
(2006)
Ageing Research Reviews
, vol.5
, Issue.1
, pp. 60-90
-
-
Bregegere, F.1
Milner, Y.2
Friguet, B.3
-
253
-
-
0033921321
-
Induction of transcriptional activity of AP-1 and NF-kappaB in the gastric mucosa during aging
-
Z.Q. Xiao, and A.P. Majumdar Induction of transcriptional activity of AP-1 and NF-kappaB in the gastric mucosa during aging Am. J. Physiol. Gastrointest. Liver Physiol. 278 2000 G855 G865
-
(2000)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.278
-
-
Xiao, Z.Q.1
Majumdar, A.P.2
-
254
-
-
80052333741
-
Aerobic exercise reverses arterial inflammation with aging in mice
-
L.A. Lesniewski, J.R. Durrant, M.L. Connell, G.D. Henson, A.D. Black, A.J. Donato, and D.R. Seals Aerobic exercise reverses arterial inflammation with aging in mice Am. J. Physiol. Heart Circ. Physol 301 2011 H1025 H1032
-
(2011)
Am. J. Physiol. Heart Circ. Physol
, vol.301
-
-
Lesniewski, L.A.1
Durrant, J.R.2
Connell, M.L.3
Henson, G.D.4
Black, A.D.5
Donato, A.J.6
Seals, D.R.7
-
255
-
-
37249009271
-
Motif module map reveals enforcement of aging by continual NF-κB activity
-
DOI 10.1101/gad.1588507
-
A.S. Adler, S. Sinha, T.L. Kawahara, J.Y. Zhang, E. Segal, and H.Y. Chang Motif module map reveals enforcement of aging by continual NF-kappaB activity Genes Dev. 21 2007 3244 3257 (Pubitemid 350277752)
-
(2007)
Genes and Development
, vol.21
, Issue.24
, pp. 3244-3257
-
-
Adler, A.S.1
Sinha, S.2
Kawahara, T.L.A.3
Zhang, J.Y.4
Segal, E.5
Chang, H.Y.6
-
256
-
-
33645870996
-
Adaptive mechanisms to oxidative stress during aging
-
B.P. Yu, and H.Y. Chung Adaptive mechanisms to oxidative stress during aging Mech. Ageing Dev. 127 2006 436 443
-
(2006)
Mech. Ageing Dev.
, vol.127
, pp. 436-443
-
-
Yu, B.P.1
Chung, H.Y.2
-
258
-
-
84860246804
-
STAT1 mediates cellular senescence induced by angiotensin II and H(2)O(2) in human glomerular mesangial cells
-
S. Jiao, F. Meng, J. Zhang, X. Yang, X. Zheng, and L. Wang STAT1 mediates cellular senescence induced by angiotensin II and H(2)O(2) in human glomerular mesangial cells Mol. Cell. Biochem. 365 2012 9 17
-
(2012)
Mol. Cell. Biochem.
, vol.365
, pp. 9-17
-
-
Jiao, S.1
Meng, F.2
Zhang, J.3
Yang, X.4
Zheng, X.5
Wang, L.6
-
260
-
-
84857914467
-
Blockade of the nuclear factor-kappaB pathway in the endothelium prevents insulin resistance and prolongs life spans
-
Y. Hasegawa, T. Saito, T. Ogihara, Y. Ishigaki, T. Yamada, J. Imai, K. Uno, J. Gao, K. Kaneko, T. Shimosawa, T. Asano, T. Fujita, Y. Oka, and H. Katagiri Blockade of the nuclear factor-kappaB pathway in the endothelium prevents insulin resistance and prolongs life spans Circulation 125 2012 1122 1133
-
(2012)
Circulation
, vol.125
, pp. 1122-1133
-
-
Hasegawa, Y.1
Saito, T.2
Ogihara, T.3
Ishigaki, Y.4
Yamada, T.5
Imai, J.6
Uno, K.7
Gao, J.8
Kaneko, K.9
Shimosawa, T.10
Asano, T.11
Fujita, T.12
Oka, Y.13
Katagiri, H.14
-
261
-
-
63649097932
-
Nuclear factor-{kappa}B activation contributes to vascular endothelial dysfunction via oxidative stress in overweight/obese middle-aged and older humans
-
G.L. Pierce, L.A. Lesniewski, B.R. Lawson, S.D. Beske, and D.R. Seals Nuclear factor-{kappa}B activation contributes to vascular endothelial dysfunction via oxidative stress in overweight/obese middle-aged and older humans Circulation 119 2009 1284 1292
-
(2009)
Circulation
, vol.119
, pp. 1284-1292
-
-
Pierce, G.L.1
Lesniewski, L.A.2
Lawson, B.R.3
Beske, S.D.4
Seals, D.R.5
-
262
-
-
84872008953
-
Sirtuins and renal diseases: Relationship with aging and diabetic nephropathy
-
M. Kitada, S. Kume, A. Takeda-Watanabe, K. Kanasaki, and D. Koya Sirtuins and renal diseases: relationship with aging and diabetic nephropathy Clin. Sci. (Lond.) 124 2013 153 164
-
(2013)
Clin. Sci. (Lond.)
, vol.124
, pp. 153-164
-
-
Kitada, M.1
Kume, S.2
Takeda-Watanabe, A.3
Kanasaki, K.4
Koya, D.5
-
264
-
-
35549008884
-
SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase
-
DOI 10.1073/pnas.0704329104
-
I. Mattagajasingh, C.S. Kim, A. Naqvi, T. Yamamori, T.A. Hoffman, S.B. Jung, J. DeRicco, K. Kasuno, and K. Irani SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase Proc. Natl. Acad. Sci. USA 104 2007 14855 14860 (Pubitemid 350003232)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.37
, pp. 14855-14860
-
-
Mattagajasingh, I.1
Kim, C.-S.2
Naqvi, A.3
Yamamori, T.4
Hoffman, T.A.5
Jung, S.-B.6
DeRicco, J.7
Kasuno, K.8
Irani, K.9
-
265
-
-
84860247019
-
Regulation of cerebral vascular function by sirtuin 1
-
N. Tajbakhsh, and E.M. Sokoya Regulation of cerebral vascular function by sirtuin 1 Microcirculation 19 2012 336 342
-
(2012)
Microcirculation
, vol.19
, pp. 336-342
-
-
Tajbakhsh, N.1
Sokoya, E.M.2
-
266
-
-
80052807171
-
SIRT-1 and vascular endothelial dysfunction with ageing in mice and humans
-
A.J. Donato, K.A. Magerko, B.R. Lawson, J.R. Durrant, L.A. Lesniewski, and D.R. Seals SIRT-1 and vascular endothelial dysfunction with ageing in mice and humans J. Physiol. 589 2011 4545 4554
-
(2011)
J. Physiol.
, vol.589
, pp. 4545-4554
-
-
Donato, A.J.1
Magerko, K.A.2
Lawson, B.R.3
Durrant, J.R.4
Lesniewski, L.A.5
Seals, D.R.6
-
267
-
-
77956701448
-
Short-term calorie restriction reverses vascular endothelial dysfunction in old mice by increasing nitric oxide and reducing oxidative stress
-
C. Rippe, L. Lesniewski, M. Connell, T. LaRocca, A. Donato, and D. Seals Short-term calorie restriction reverses vascular endothelial dysfunction in old mice by increasing nitric oxide and reducing oxidative stress Aging Cell 9 2010 304 312
-
(2010)
Aging Cell
, vol.9
, pp. 304-312
-
-
Rippe, C.1
Lesniewski, L.2
Connell, M.3
Larocca, T.4
Donato, A.5
Seals, D.6
-
268
-
-
33748164460
-
Vascular smooth muscle cell senescence in atherosclerosis
-
DOI 10.1016/j.cardiores.2006.06.004, PII S0008636306002550
-
I. Gorenne, M. Kavurma, S. Scott, and M. Bennett Vascular smooth muscle cell senescence in atherosclerosis Cardiovasc. Res. 72 2006 9 17 (Pubitemid 44310633)
-
(2006)
Cardiovascular Research
, vol.72
, Issue.1
, pp. 9-17
-
-
Gorenne, I.1
Kavurma, M.2
Scott, S.3
Bennett, M.4
-
269
-
-
34249696938
-
Extension of human cell lifespan by nicotinamide phosphoribosyltransferase
-
DOI 10.1074/jbc.C700018200
-
E. van der Veer, C. Ho, C. O'Neil, N. Barbosa, R. Scott, S.P. Cregan, and J.G. Pickering Extension of human cell lifespan by nicotinamide phosphoribosyltransferase J. Biol. Chem. 282 2007 10841 10845 (Pubitemid 47100731)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.15
, pp. 10841-10845
-
-
Van Der Veer, E.1
Ho, C.2
O'Neil, C.3
Barbosa, N.4
Scott, R.5
Cregan, S.P.6
Pickering, J.G.7
-
270
-
-
46249095235
-
SIRT1, a longevity gene, downregulates angiotensin II type 1 receptor expression in vascular smooth muscle cells
-
R. Miyazaki, T. Ichiki, T. Hashimoto, K. Inanaga, I. Imayama, J. Sadoshima, and K. Sunagawa SIRT1, a longevity gene, downregulates angiotensin II type 1 receptor expression in vascular smooth muscle cells Arterioscler. Thromb. Vasc. Biol. 28 2008 1263 1269
-
(2008)
Arterioscler. Thromb. Vasc. Biol.
, vol.28
, pp. 1263-1269
-
-
Miyazaki, R.1
Ichiki, T.2
Hashimoto, T.3
Inanaga, K.4
Imayama, I.5
Sadoshima, J.6
Sunagawa, K.7
-
271
-
-
42749097951
-
Losartan improves impaired nitric oxide synthase-dependent dilatation of cerebral arterioles in type 1 diabetic rats
-
D.M. Arrick, G.M. Sharpe, H. Sun, and W.G. Mayhan Losartan improves impaired nitric oxide synthase-dependent dilatation of cerebral arterioles in type 1 diabetic rats Brain Res. 1209 2008 128 135
-
(2008)
Brain Res.
, vol.1209
, pp. 128-135
-
-
Arrick, D.M.1
Sharpe, G.M.2
Sun, H.3
Mayhan, W.G.4
-
272
-
-
40949123149
-
Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging
-
DOI 10.1016/j.arr.2007.09.002, PII S1568163707000566
-
A. Salminen, J. Huuskonen, J. Ojala, A. Kauppinen, K. Kaarniranta, and T. Suuronen Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging Ageing Res. Rev. 7 2008 83 105 (Pubitemid 351418294)
-
(2008)
Ageing Research Reviews
, vol.7
, Issue.2
, pp. 83-105
-
-
Salminen, A.1
Huuskonen, J.2
Ojala, J.3
Kauppinen, A.4
Kaarniranta, K.5
Suuronen, T.6
-
273
-
-
3242719545
-
Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase
-
DOI 10.1038/sj.emboj.7600244
-
F. Yeung, J.E. Hoberg, C.S. Ramsey, M.D. Keller, D.R. Jones, R.A. Frye, and M.W. Mayo Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase EMBO J. 23 2004 2369 2380 (Pubitemid 38954844)
-
(2004)
EMBO Journal
, vol.23
, Issue.12
, pp. 2369-2380
-
-
Yeung, F.1
Hoberg, J.E.2
Ramsey, C.S.3
Keller, M.D.4
Jones, D.R.5
Frye, R.A.6
Mayo, M.W.7
-
274
-
-
80052078788
-
The physiological roles of Sirt1 in skeletal muscle
-
P.S. Pardo, and A.M. Boriek The physiological roles of Sirt1 in skeletal muscle Aging (Albany NY) 3 2011 430 437
-
(2011)
Aging (Albany NY)
, vol.3
, pp. 430-437
-
-
Pardo, P.S.1
Boriek, A.M.2
-
275
-
-
58149090925
-
SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span
-
T.L. Kawahara, E. Michishita, A.S. Adler, M. Damian, E. Berber, M. Lin, R.A. McCord, K.C. Ongaigui, L.D. Boxer, H.Y. Chang, and K.F. Chua SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span Cell 136 2009 62 74
-
(2009)
Cell
, vol.136
, pp. 62-74
-
-
Kawahara, T.L.1
Michishita, E.2
Adler, A.S.3
Damian, M.4
Berber, E.5
Lin, M.6
McCord, R.A.7
Ongaigui, K.C.8
Boxer, L.D.9
Chang, H.Y.10
Chua, K.F.11
-
276
-
-
79960046164
-
Cellular stress response pathways and ageing: Intricate molecular relationships
-
N. Kourtis, and N. Tavernarakis Cellular stress response pathways and ageing: intricate molecular relationships EMBO J. 30 2011 2520 2531
-
(2011)
EMBO J.
, vol.30
, pp. 2520-2531
-
-
Kourtis, N.1
Tavernarakis, N.2
-
277
-
-
84876012415
-
Redox-regulating sirtuins in aging, caloric restriction, and exercise
-
Z. Radak, E. Koltai, A.W. Taylor, M. Higuchi, S. Kumagai, H. Ohno, S. Goto, and I. Boldogh Redox-regulating sirtuins in aging, caloric restriction, and exercise Free Radic. Biol. Med. 58 2013 87 97
-
(2013)
Free Radic. Biol. Med.
, vol.58
, pp. 87-97
-
-
Radak, Z.1
Koltai, E.2
Taylor, A.W.3
Higuchi, M.4
Kumagai, S.5
Ohno, H.6
Goto, S.7
Boldogh, I.8
-
278
-
-
79960027346
-
Interaction of p53 with tumor suppressive and oncogenic signaling pathways to control cellular reactive oxygen species production
-
M.F. Ladelfa, M.F. Toledo, J.E. Laiseca, and M. Monte Interaction of p53 with tumor suppressive and oncogenic signaling pathways to control cellular reactive oxygen species production Antioxid. Redox Signal. 15 2011 1749 1761
-
(2011)
Antioxid. Redox Signal.
, vol.15
, pp. 1749-1761
-
-
Ladelfa, M.F.1
Toledo, M.F.2
Laiseca, J.E.3
Monte, M.4
-
281
-
-
79952501323
-
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1alpha destabilization
-
L.W. Finley, A. Carracedo, J. Lee, A. Souza, A. Egia, J. Zhang, J. Teruya-Feldstein, P.I. Moreira, S.M. Cardoso, C.B. Clish, P.P. Pandolfi, and M.C. Haigis SIRT3 opposes reprogramming of cancer cell metabolism through HIF1alpha destabilization Cancer Cell 19 2011 416 428
-
(2011)
Cancer Cell
, vol.19
, pp. 416-428
-
-
Finley, L.W.1
Carracedo, A.2
Lee, J.3
Souza, A.4
Egia, A.5
Zhang, J.6
Teruya-Feldstein, J.7
Moreira, P.I.8
Cardoso, S.M.9
Clish, C.B.10
Pandolfi, P.P.11
Haigis, M.C.12
-
282
-
-
84860743760
-
FOXOs and sirtuins in vascular growth, maintenance, and aging
-
M.F. Oellerich, and M. Potente FOXOs and sirtuins in vascular growth, maintenance, and aging Circ. Res. 110 2012 1238 1251
-
(2012)
Circ. Res.
, vol.110
, pp. 1238-1251
-
-
Oellerich, M.F.1
Potente, M.2
-
283
-
-
12144290563
-
Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase
-
DOI 10.1126/science.1094637
-
A. Brunet, L.B. Sweeney, J.F. Sturgill, K.F. Chua, P.L. Greer, Y. Lin, H. Tran, S.E. Ross, R. Mostoslavsky, H.Y. Cohen, L.S. Hu, H.L. Cheng, M.P. Jedrychowski, S.P. Gygi, D.A. Sinclair, F.W. Alt, and M.E. Greenberg Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase Science 303 2004 2011 2015 (Pubitemid 38393275)
-
(2004)
Science
, vol.303
, Issue.5666
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
Tran, H.7
Ross, S.E.8
Mostoslavsy, R.9
Cohen, H.Y.10
Hu, L.S.11
Cheng, H.-L.12
Jedrychowski, M.P.13
Gygi, S.P.14
Sinclair, D.A.15
Alt, F.W.16
Greenberg, M.E.17
-
284
-
-
84860809347
-
SIRT3, a pivotal actor in mitochondrial functions: Metabolism, cell death and aging
-
A. Giralt, and F. Villarroya SIRT3, a pivotal actor in mitochondrial functions: metabolism, cell death and aging Biochem. J. 444 2012 1 10
-
(2012)
Biochem. J.
, vol.444
, pp. 1-10
-
-
Giralt, A.1
Villarroya, F.2
-
285
-
-
78649521247
-
Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation
-
X. Qiu, K. Brown, M.D. Hirschey, E. Verdin, and D. Chen Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation Cell Metab. 12 2010 662 667
-
(2010)
Cell Metab.
, vol.12
, pp. 662-667
-
-
Qiu, X.1
Brown, K.2
Hirschey, M.D.3
Verdin, E.4
Chen, D.5
-
286
-
-
84868023147
-
Caloric restriction: Is mammalian life extension linked to p53?
-
P. Tucci Caloric restriction: is mammalian life extension linked to p53? Aging (Albany NY) 4 2012 525 534
-
(2012)
Aging (Albany NY)
, vol.4
, pp. 525-534
-
-
Tucci, P.1
-
287
-
-
84875667635
-
Seven sirtuins for seven deadly diseases of aging
-
Morris, B. J. Seven sirtuins for seven deadly diseases of aging. Free Radic. Biol. Med.; 2012.
-
(2012)
Free Radic. Biol. Med.
-
-
Morris, B.J.1
-
288
-
-
37349115260
-
Effects of aging and hypoxia-inducible factor-1 activity on angiogenic
-
DOI 10.1161/CIRCRESAHA.107.153346, PII 0000301220071207000014
-
M. Bosch-Marce, H. Okuyama, J.B. Wesley, K. Sarkar, H. Kimura, Y.V. Liu, H. Zhang, M. Strazza, S. Rey, L. Savino, Y.F. Zhou, K.R. McDonald, Y. Na, S. Vandiver, A. Rabi, Y. Shaked, R. Kerbel, T. Lavallee, and G.L. Semenza Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia Circ. Res. 101 2007 1310 1318 (Pubitemid 350294648)
-
(2007)
Circulation Research
, vol.101
, Issue.12
, pp. 1310-1318
-
-
Bosch-Marce, M.1
Okuyama, H.2
Wesley, J.B.3
Sarkar, K.4
Kimura, H.5
Liu, Y.V.6
Zhang, H.7
Strazza, M.8
Rey, S.9
Savino, L.10
Zhou, Y.F.11
McDonald, K.R.12
Na, Y.13
Vandiver, S.14
Rabi, A.15
Shaked, Y.16
Kerbel, R.17
LaVallee, T.18
Semenza, G.L.19
-
289
-
-
78649364332
-
Hypoxia-inducible factors and the response to hypoxic stress
-
A.J. Majmundar, W.J. Wong, and M.C. Simon Hypoxia-inducible factors and the response to hypoxic stress Mol. Cell 40 2010 294 309
-
(2010)
Mol. Cell
, vol.40
, pp. 294-309
-
-
Majmundar, A.J.1
Wong, W.J.2
Simon, M.C.3
-
290
-
-
0032748767
-
The function of hypoxia-inducible factor 1 (HIF-1) is impaired in senescent mice
-
G. Frenkel-Denkberg, D. Gershon, and A.P. Levy The function of hypoxia-inducible factor 1 (HIF-1) is impaired in senescent mice FEBS Lett 462 1999 341 344
-
(1999)
FEBS Lett
, vol.462
, pp. 341-344
-
-
Frenkel-Denkberg, G.1
Gershon, D.2
Levy, A.P.3
-
291
-
-
0034703017
-
Age-dependent defect in vascular endothelial growth factor expression is associated with reduced hypoxia-inducible factor 1 activity
-
DOI 10.1074/jbc.M001029200
-
A. Rivard, and L. Berthou-Soulie Principe, N.; Kearney, M.; Curry, C.; Branellec, D.; Semenza, G. L.; Isner, J. M. Age-dependent defect in vascular endothelial growth factor expression is associated with reduced hypoxia-inducible factor 1 activity J. Biol. Chem. 275 2000 29643 29647 (Pubitemid 32043844)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.38
, pp. 29643-29647
-
-
Rivard, A.1
Berthou-Soulie, L.2
Principe, N.3
Kearney, M.4
Curry, C.5
Branellec, D.6
Semenza, G.L.7
Isner, J.M.8
-
292
-
-
67650065272
-
Increased prolyl 4-hydroxylase expression and differential regulation of hypoxia-inducible factors in the aged rat brain
-
O.I. Ndubuizu, J.C. Chavez, and J.C. LaManna Increased prolyl 4-hydroxylase expression and differential regulation of hypoxia-inducible factors in the aged rat brain Am. J. Physiol. Regul. Integr. Comp. Physiol 297 2009 R158 R165
-
(2009)
Am. J. Physiol. Regul. Integr. Comp. Physiol
, vol.297
-
-
Ndubuizu, O.I.1
Chavez, J.C.2
Lamanna, J.C.3
-
293
-
-
23644461909
-
Age-dependent increase of prolyl-4-hydroxylase domain (PHD) 3 expression in human and mouse heart
-
DOI 10.1007/s10522-005-7950-9
-
S. Rohrbach, A. Simm, R. Pregla, C. Franke, and D.M. Katschinski Age-dependent increase of prolyl-4-hydroxylase domain (PHD) 3 expression in human and mouse heart Biogerontology 6 2005 165 171 (Pubitemid 41131166)
-
(2005)
Biogerontology
, vol.6
, Issue.3
, pp. 165-171
-
-
Rohrbach, S.1
Simm, A.2
Pregla, R.3
Franke, C.4
Katschinski, D.M.5
-
294
-
-
43249114609
-
Caloric restriction counteracts age-dependent changes in prolyl-4-hydroxylase domain (PHD) 3 expression
-
S. Rohrbach, S. Teichert, B. Niemann, C. Franke, and D.M. Katschinski Caloric restriction counteracts age-dependent changes in prolyl-4-hydroxylase domain (PHD) 3 expression Biogerontology 9 2008 169 176
-
(2008)
Biogerontology
, vol.9
, pp. 169-176
-
-
Rohrbach, S.1
Teichert, S.2
Niemann, B.3
Franke, C.4
Katschinski, D.M.5
-
295
-
-
80052404569
-
Impaired hypoxic response in senescent mouse brain
-
T. Rabie, R. Kunze, and H.H. Marti Impaired hypoxic response in senescent mouse brain Int. J. Dev. Neurosci. 29 2011 655 661
-
(2011)
Int. J. Dev. Neurosci.
, vol.29
, pp. 655-661
-
-
Rabie, T.1
Kunze, R.2
Marti, H.H.3
-
296
-
-
73949085704
-
Synergistic effect of HIF-1alpha gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
-
S. Rey, K. Lee, C.J. Wang, K. Gupta, S. Chen, A. McMillan, N. Bhise, A. Levchenko, and G.L. Semenza Synergistic effect of HIF-1alpha gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia Proc. Natl. Acad. Sci. USA 106 2009 20399 20404
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 20399-20404
-
-
Rey, S.1
Lee, K.2
Wang, C.J.3
Gupta, K.4
Chen, S.5
McMillan, A.6
Bhise, N.7
Levchenko, A.8
Semenza, G.L.9
-
297
-
-
84885586061
-
Impaired cross-activation of beta integrin and VEGFR-2 on endothelial progenitor cells with aging decreases angiogenesis in response to hypoxia
-
Di, Q.; Cheng, Z.; Kim, W.; Liu, Z.; Song, H.; Li, X.; Nan, Y.; Wang, C.; Cheng, X. Impaired cross-activation of beta integrin and VEGFR-2 on endothelial progenitor cells with aging decreases angiogenesis in response to hypoxia. Int. J. Cardiol.; 2013.
-
(2013)
Int. J. Cardiol.
-
-
Di, Q.1
Cheng, Z.2
Kim, W.3
Liu, Z.4
Song, H.5
Li, X.6
Nan, Y.7
Wang, C.8
Cheng, X.9
-
298
-
-
77952512346
-
Hypoxia-inducible factor-1 improves inotropic responses of cardiac myocytes in ageing heart without affecting mitochondrial activity
-
T. Tan, J. Marin-Garcia, S. Damle, and H.R. Weiss Hypoxia-inducible factor-1 improves inotropic responses of cardiac myocytes in ageing heart without affecting mitochondrial activity Exp. Physiol 95 2010 712 722
-
(2010)
Exp. Physiol
, vol.95
, pp. 712-722
-
-
Tan, T.1
Marin-Garcia, J.2
Damle, S.3
Weiss, H.R.4
-
299
-
-
59249107409
-
Decreased vascular repair and neovascularization with ageing: Mechanisms and clinical relevance with an emphasis on hypoxia-inducible factor-1
-
M.R. Hoenig, C. Bianchi, A. Rosenzweig, and F.W. Sellke Decreased vascular repair and neovascularization with ageing: mechanisms and clinical relevance with an emphasis on hypoxia-inducible factor-1 Curr. Mol. Med. 8 2008 754 767
-
(2008)
Curr. Mol. Med.
, vol.8
, pp. 754-767
-
-
Hoenig, M.R.1
Bianchi, C.2
Rosenzweig, A.3
Sellke, F.W.4
-
300
-
-
37349021749
-
Age decreases endothelial progenitor cell recruitment through decreases in hypoxia-inducible factor 1α stabilization during ischemia
-
DOI 10.1161/CIRCULATIONAHA.107.715847
-
E.I. Chang, S.A. Loh, D.J. Ceradini, E.I. Chang, S.E. Lin, N. Bastidas, S. Aarabi, D.A. Chan, M.L. Freedman, A.J. Giaccia, and G.C. Gurtner Age decreases endothelial progenitor cell recruitment through decreases in hypoxia-inducible factor 1alpha stabilization during ischemia Circulation 116 2007 2818 2829 (Pubitemid 350291224)
-
(2007)
Circulation
, vol.116
, Issue.24
, pp. 2818-2829
-
-
Chang, E.I.1
Loh, S.A.2
Ceradini, D.J.3
Chang, E.I.4
Lin, S.-E.5
Bastidas, N.6
Aarabi, S.7
Chan, D.A.8
Freedman, M.L.9
Giaccia, A.J.10
Gurtner, G.C.11
-
301
-
-
67149107430
-
HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegans
-
D. Chen, E.L. Thomas, and P. Kapahi HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegans PLoS Genet. 5 2009 e1000486
-
(2009)
PLoS Genet.
, vol.5
, pp. 1000486
-
-
Chen, D.1
Thomas, E.L.2
Kapahi, P.3
-
302
-
-
68149149835
-
The HIF-1 hypoxia-inducible factor modulates lifespan in C elegans
-
Y. Zhang, Z. Shao, Z. Zhai, C. Shen, and J.A. Powell-Coffman The HIF-1 hypoxia-inducible factor modulates lifespan in C. elegans PLoS One 4 2009 e6348
-
(2009)
PLoS One
, vol.4
, pp. 6348
-
-
Zhang, Y.1
Shao, Z.2
Zhai, Z.3
Shen, C.4
Powell-Coffman, J.A.5
-
303
-
-
78650177082
-
Inhibition of respiration extends C elegans life span via reactive oxygen species that increase HIF-1 activity
-
S.J. Lee, A.B. Hwang, and C. Kenyon Inhibition of respiration extends C. elegans life span via reactive oxygen species that increase HIF-1 activity Curr. Biol. 20 2010 2131 2136
-
(2010)
Curr. Biol.
, vol.20
, pp. 2131-2136
-
-
Lee, S.J.1
Hwang, A.B.2
Kenyon, C.3
-
304
-
-
79952582588
-
HIF-1 modulates longevity and healthspan in a temperature-dependent manner
-
S.F. Leiser, A. Begun, and M. Kaeberlein HIF-1 modulates longevity and healthspan in a temperature-dependent manner Aging Cell 10 2011 318 326
-
(2011)
Aging Cell
, vol.10
, pp. 318-326
-
-
Leiser, S.F.1
Begun, A.2
Kaeberlein, M.3
-
305
-
-
34547914798
-
Mitochondrial reactive oxygen species trigger hypoxia-inducible factor-dependent extension of the replicative life span during hypoxia
-
DOI 10.1128/MCB.02265-06
-
E.L. Bell, T.A. Klimova, J. Eisenbart, P.T. Schumacker, and N.S. Chandel Mitochondrial reactive oxygen species trigger hypoxia-inducible factor-dependent extension of the replicative life span during hypoxia Mol. Cell. Biol. 27 2007 5737 5745 (Pubitemid 47257830)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.16
, pp. 5737-5745
-
-
Bell, E.L.1
Klimova, T.A.2
Eisenbart, J.3
Schumacker, P.T.4
Chandel, N.S.5
-
306
-
-
34548074395
-
The opposing effect of hypoxia-inducible factor-2α on expression of telomerase reverse transcriptase
-
DOI 10.1158/1541-7786.MCR-07-0065
-
F. Lou, X. Chen, M. Jalink, Q. Zhu, N. Ge, S. Zhao, X. Fang, Y. Fan, M. Bjorkholm, Z. Liu, and D. Xu The opposing effect of hypoxia-inducible factor-2alpha on expression of telomerase reverse transcriptase Mol. Cancer Res. 5 2007 793 800 (Pubitemid 47294807)
-
(2007)
Molecular Cancer Research
, vol.5
, Issue.8
, pp. 793-800
-
-
Lou, F.1
Chen, X.2
Jalink, M.3
Zhu, Q.4
Ge, N.5
Zhao, S.6
Fang, X.7
Fan, Y.8
Bjorkholm, M.9
Liu, Z.10
Xu, D.11
-
307
-
-
77952551627
-
Lifelong protection from global cerebral ischemia and reperfusion in long-lived Mclk1(+/)(-) mutants
-
H. Zheng, J. Lapointe, and S. Hekimi Lifelong protection from global cerebral ischemia and reperfusion in long-lived Mclk1(+/)(-) mutants Exp. Neurol. 223 2010 557 565
-
(2010)
Exp. Neurol.
, vol.223
, pp. 557-565
-
-
Zheng, H.1
Lapointe, J.2
Hekimi, S.3
-
308
-
-
56349161639
-
The angiotensin II type 2 receptor: What is its clinical significance?
-
I.H. Schulman, and L. Raij The angiotensin II type 2 receptor: what is its clinical significance? Curr. Hypertens Rep. 10 2008 188 193
-
(2008)
Curr. Hypertens Rep.
, vol.10
, pp. 188-193
-
-
Schulman, I.H.1
Raij, L.2
-
309
-
-
77956896591
-
Angiotensin II revisited: New roles in inflammation, immunology and aging
-
A. Benigni, P. Cassis, and G. Remuzzi Angiotensin II revisited: new roles in inflammation, immunology and aging EMBO Mol. Med 2 2010 247 257
-
(2010)
EMBO Mol. Med
, vol.2
, pp. 247-257
-
-
Benigni, A.1
Cassis, P.2
Remuzzi, G.3
-
310
-
-
84866484686
-
Distribution of the activity of the angiotensin-converting enzyme in the rat aorta and changes in the activity with aging and by the action of L-NAME
-
A.F. Korystova, M.O. Emel'yanov, L.N. Kublik, M. Levitman, V.V. Shaposhnikova, Y.A. Kim, and Y.N. Korystov Distribution of the activity of the angiotensin-converting enzyme in the rat aorta and changes in the activity with aging and by the action of L-NAME Age (Dordr.) 34 2012 821 830
-
(2012)
Age (Dordr.)
, vol.34
, pp. 821-830
-
-
Korystova, A.F.1
Emel'Yanov, M.O.2
Kublik, L.N.3
Levitman, M.4
Shaposhnikova, V.V.5
Kim, Y.A.6
Korystov, Y.N.7
-
311
-
-
48249108338
-
Increased aortic calpain-1 activity mediates age-associated angiotensin II signaling of vascular smooth muscle cells
-
L. Jiang, M. Wang, J. Zhang, R.E. Monticone, R. Telljohann, G. Spinetti, G. Pintus, and E.G. Lakatta Increased aortic calpain-1 activity mediates age-associated angiotensin II signaling of vascular smooth muscle cells PLoS One 3 2008 e2231
-
(2008)
PLoS One
, vol.3
, pp. 2231
-
-
Jiang, L.1
Wang, M.2
Zhang, J.3
Monticone, R.E.4
Telljohann, R.5
Spinetti, G.6
Pintus, G.7
Lakatta, E.G.8
-
312
-
-
45849086107
-
Role of the renin-angiotensin system in vascular inflammation
-
C. Marchesi, P. Paradis, and E.L. Schiffrin Role of the renin-angiotensin system in vascular inflammation Trends Pharmacol. Sci. 29 2008 367 374
-
(2008)
Trends Pharmacol. Sci.
, vol.29
, pp. 367-374
-
-
Marchesi, C.1
Paradis, P.2
Schiffrin, E.L.3
-
313
-
-
0038300382
-
Endothelial activation by angiotensin II through NFκB and p38 pathways: Involvement of NFκB-inducible kinase (NIK), free oxygen radicals, and selective inhibition by aspirin
-
DOI 10.1002/jcp.10191
-
A. Costanzo, F. Moretti, V.L. Burgio, C. Bravi, F. Guido, M. Levrero, and P.L. Puri Endothelial activation by angiotensin II through NFkappaB and p38 pathways: Involvement of NFkappaB-inducible kinase (NIK), free oxygen radicals, and selective inhibition by aspirin J. Cell Physiol. 195 2003 402 410 (Pubitemid 36531523)
-
(2003)
Journal of Cellular Physiology
, vol.195
, Issue.3
, pp. 402-410
-
-
Costanzo, A.1
Moretti, F.2
Burgio, V.L.3
Bravi, C.4
Guido, F.5
Levrero, M.6
Puri, P.L.7
-
314
-
-
79960060935
-
Angiotensin II modulates interleukin-1beta-induced inflammatory gene expression in vascular smooth muscle cells via interfering with ERK-NF-kappaB crosstalk
-
S. Xu, H. Zhi, X. Hou, and B. Jiang Angiotensin II modulates interleukin-1beta-induced inflammatory gene expression in vascular smooth muscle cells via interfering with ERK-NF-kappaB crosstalk Biochem. Biophys. Res. Commun 410 2011 543 548
-
(2011)
Biochem. Biophys. Res. Commun
, vol.410
, pp. 543-548
-
-
Xu, S.1
Zhi, H.2
Hou, X.3
Jiang, B.4
-
315
-
-
46449086217
-
Angiotensin II-dependent superoxide: Effects on hypertension and vascular dysfunction
-
W.J. Welch Angiotensin II-dependent superoxide: effects on hypertension and vascular dysfunction Hypertension 52 2008 51 56
-
(2008)
Hypertension
, vol.52
, pp. 51-56
-
-
Welch, W.J.1
-
316
-
-
1642369185
-
Reactive oxygen species in vascular biology: Role in arterial hypertension
-
R.M. Touyz Reactive oxygen species in vascular biology: role in arterial hypertension Expert Rev. Cardiovasc. Ther. 1 2003 91 106
-
(2003)
Expert Rev. Cardiovasc. Ther.
, vol.1
, pp. 91-106
-
-
Touyz, R.M.1
-
317
-
-
35548983106
-
From mitochondria to disease: Role of the renin-angiotensin system
-
DOI 10.1159/000107757
-
(de) E.M. Cavanagh, F. Inserra, M. Ferder, and L. Ferder From mitochondria to disease: role of the renin-angiotensin system Am. J. Nephrol. 27 2007 545 553 (Pubitemid 350014941)
-
(2007)
American Journal of Nephrology
, vol.27
, Issue.6
, pp. 545-553
-
-
De Cavanagh, E.M.V.1
Inserra, F.2
Ferder, M.3
Ferder, L.4
-
318
-
-
68549101834
-
Attenuation of angiotensin II-induced vascular dysfunction and hypertension by overexpression of thioredoxin 2
-
J.D. Widder, D. Fraccarollo, P. Galuppo, J.M. Hansen, D.P. Jones, G. Ertl, and J. Bauersachs Attenuation of angiotensin II-induced vascular dysfunction and hypertension by overexpression of thioredoxin 2 Hypertension 54 2009 338 344
-
(2009)
Hypertension
, vol.54
, pp. 338-344
-
-
Widder, J.D.1
Fraccarollo, D.2
Galuppo, P.3
Hansen, J.M.4
Jones, D.P.5
Ertl, G.6
Bauersachs, J.7
-
319
-
-
23244434000
-
Shc adaptor protein protects from angiotensin II-induced myocardial damage
-
DOI 10.1161/01.HYP.0000174986.73346.ba
-
G. Graiani, C. Lagrasta, E. Migliaccio, F. Spillmann, M. Meloni, P. Madeddu, F. Quaini, I.M. Padura, L. Lanfrancone, P. Pelicci, and C. Emanueli Genetic deletion of the p66Shc adaptor protein protects from angiotensin II-induced myocardial damage Hypertension 46 2005 433 440 (Pubitemid 41099181)
-
(2005)
Hypertension
, vol.46
, Issue.2
, pp. 433-440
-
-
Graiani, G.1
Lagrasta, C.2
Migliaccio, E.3
Spillmann, F.4
Meloni, M.5
Madeddu, P.6
Quaini, F.7
Padura, I.M.8
Lanfrancone, L.9
Pelicci, P.10
Emanueli, C.11
-
320
-
-
78650456535
-
Angiotensin II blockade: A strategy to slow ageing by protecting mitochondria?
-
(de)
-
(de) E.M. Cavanagh, F. Inserra, and L. Ferder Angiotensin II blockade: a strategy to slow ageing by protecting mitochondria? Cardiovasc. Res. 89 2011 31 40
-
(2011)
Cardiovasc. Res.
, vol.89
, pp. 31-40
-
-
Cavanagh, E.M.1
Inserra, F.2
Ferder, L.3
-
321
-
-
1442274621
-
Activated oxygen metabolites: Do they really play a role in angiotensin II-regulated vascular tone?
-
DOI 10.1097/00004872-200312000-00007
-
R.M. Touyz Activated oxygen metabolites: do they really play a role in angiotensin II-regulated vascular tone? J. Hypertens 21 2003 2235 2238 (Pubitemid 38293558)
-
(2003)
Journal of Hypertension
, vol.21
, Issue.12
, pp. 2235-2238
-
-
Touyz, R.M.1
-
322
-
-
65349128571
-
Disruption of the Ang II type 1 receptor promotes longevity in mice
-
A. Benigni, D. Corna, C. Zoja, A. Sonzogni, R. Latini, M. Salio, S. Conti, D. Rottoli, L. Longaretti, P. Cassis, M. Morigi, T.M. Coffman, and G. Remuzzi Disruption of the Ang II type 1 receptor promotes longevity in mice J. Clin. Invest. 119 2009 524 530
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 524-530
-
-
Benigni, A.1
Corna, D.2
Zoja, C.3
Sonzogni, A.4
Latini, R.5
Salio, M.6
Conti, S.7
Rottoli, D.8
Longaretti, L.9
Cassis, P.10
Morigi, M.11
Coffman, T.M.12
Remuzzi, G.13
-
323
-
-
0036739890
-
Inhibition of renin-angiotensin system ameliorates endothelial dysfunction associated with aging in rats
-
Y. Mukai, H. Shimokawa, M. Higashi, K. Morikawa, T. Matoba, J. Hiroki, I. Kunihiro, H.M. Talukder, and A. Takeshita Inhibition of renin-angiotensin system ameliorates endothelial dysfunction associated with aging in rats Arterioscler. Thromb. Vasc. Biol. 22 2002 1445 1450
-
(2002)
Arterioscler. Thromb. Vasc. Biol.
, vol.22
, pp. 1445-1450
-
-
Mukai, Y.1
Shimokawa, H.2
Higashi, M.3
Morikawa, K.4
Matoba, T.5
Hiroki, J.6
Kunihiro, I.7
Talukder, H.M.8
Takeshita, A.9
-
324
-
-
0036492013
-
Angiotensin II receptor antagonist improves age-related endothelial dysfunction
-
DOI 10.1097/00004872-200203000-00019
-
Y. Kansui, K. Fujii, K. Goto, I. Abe, and M. Iida Angiotensin II receptor antagonist improves age-related endothelial dysfunction J. Hypertens. 20 2002 439 446 (Pubitemid 34913743)
-
(2002)
Journal of Hypertension
, vol.20
, Issue.3
, pp. 439-446
-
-
Kansui, Y.1
Fujii, K.2
Goto, K.3
Abe, I.4
Iida, M.5
-
325
-
-
0036499185
-
Effect of losartan in aging-related endothelial impairment
-
DOI 10.1016/S0002-9149(01)02297-4, PII S0002914901022974
-
S. Rajagopalan, R. Brook, R.H. Mehta, M. Supiano, and B. Pitt Effect of losartan in aging-related endothelial impairment Am. J. Cardiol. 89 2002 562 566 (Pubitemid 34178568)
-
(2002)
American Journal of Cardiology
, vol.89
, Issue.5
, pp. 562-566
-
-
Rajagopalan, S.1
Brook, R.2
Mehta, R.H.3
Supiano, M.4
Pitt, B.5
-
326
-
-
34547598501
-
Angiotensin receptor blockade improves vascular compliance in healthy normotensive elderly individuals: Results from a randomized double-blind placebo-controlled trial
-
S. Rajagopalan, M. Kariisa, S. Dellegrottaglie, R.L. Bard, C. Kehrer, S. Matlow, W. Daley, B. Pitt, and R. Brook Angiotensin receptor blockade improves vascular compliance in healthy normotensive elderly individuals: results from a randomized double-blind placebo-controlled trial J. Clin. Hypertens. (Greenwich) 8 2006 783 790
-
(2006)
J. Clin. Hypertens. (Greenwich)
, vol.8
, pp. 783-790
-
-
Rajagopalan, S.1
Kariisa, M.2
Dellegrottaglie, S.3
Bard, R.L.4
Kehrer, C.5
Matlow, S.6
Daley, W.7
Pitt, B.8
Brook, R.9
-
327
-
-
84866363828
-
Mechanisms involved in the aging-induced vascular dysfunction
-
M. El Assar, J. Angulo, S. Vallejo, C. Peiro, C.F. Sanchez-Ferrer, and L. Rodriguez-Manas Mechanisms involved in the aging-induced vascular dysfunction Front. Physiol 3 2012 132
-
(2012)
Front. Physiol
, vol.3
, pp. 132
-
-
El Assar, M.1
Angulo, J.2
Vallejo, S.3
Peiro, C.4
Sanchez-Ferrer, C.F.5
Rodriguez-Manas, L.6
-
328
-
-
84869087625
-
Exercise and longevity
-
V. Gremeaux, M. Gayda, R. Lepers, P. Sosner, M. Juneau, and A. Nigam Exercise and longevity Maturitas 73 2012 312 317
-
(2012)
Maturitas
, vol.73
, pp. 312-317
-
-
Gremeaux, V.1
Gayda, M.2
Lepers, R.3
Sosner, P.4
Juneau, M.5
Nigam, A.6
-
329
-
-
84863026875
-
Amount of time spent in sedentary behaviors and cause-specific mortality in US adults
-
C.E. Matthews, S.M. George, S.C. Moore, H.R. Bowles, A. Blair, Y. Park, R.P. Troiano, A. Hollenbeck, and A. Schatzkin Amount of time spent in sedentary behaviors and cause-specific mortality in US adults Am. J. Clin. Nutr. 95 2012 437 445
-
(2012)
Am. J. Clin. Nutr.
, vol.95
, pp. 437-445
-
-
Matthews, C.E.1
George, S.M.2
Moore, S.C.3
Bowles, H.R.4
Blair, A.5
Park, Y.6
Troiano, R.P.7
Hollenbeck, A.8
Schatzkin, A.9
-
331
-
-
20144387438
-
Physical activity, plasma antioxidant capacity, and endothelium-dependent vasodilation in young and older men
-
F. Franzoni, L. Ghiadoni, F. Galetta, Y. Plantinga, V. Lubrano, Y. Huang, G. Salvetti, F. Regoli, S. Taddei, G. Santoro, and A. Salvetti Physical activity, plasma antioxidant capacity, and endothelium-dependent vasodilation in young and older men Am. J. Hypertens. 18 2005 510 516
-
(2005)
Am. J. Hypertens.
, vol.18
, pp. 510-516
-
-
Franzoni, F.1
Ghiadoni, L.2
Galetta, F.3
Plantinga, Y.4
Lubrano, V.5
Huang, Y.6
Salvetti, G.7
Regoli, F.8
Taddei, S.9
Santoro, G.10
Salvetti, A.11
-
332
-
-
77955985342
-
Exercise training stimulates ischemia-induced neovascularization via phosphatidylinositol 3-kinase/Akt-dependent hypoxia-induced factor-1 alpha reactivation in mice of advanced age
-
X.W. Cheng, M. Kuzuya, W. Kim, H. Song, L. Hu, A. Inoue, K. Nakamura, Q. Di, T. Sasaki, M. Tsuzuki, G.P. Shi, K. Okumura, and T. Murohara Exercise training stimulates ischemia-induced neovascularization via phosphatidylinositol 3-kinase/Akt-dependent hypoxia-induced factor-1 alpha reactivation in mice of advanced age Circulation 122 2010 707 716
-
(2010)
Circulation
, vol.122
, pp. 707-716
-
-
Cheng, X.W.1
Kuzuya, M.2
Kim, W.3
Song, H.4
Hu, L.5
Inoue, A.6
Nakamura, K.7
Di, Q.8
Sasaki, T.9
Tsuzuki, M.10
Shi, G.P.11
Okumura, K.12
Murohara, T.13
-
333
-
-
79952718104
-
Cardiovascular protection afforded by caloric restriction: Essential role of nitric oxide synthase
-
K. Shinmura Cardiovascular protection afforded by caloric restriction: essential role of nitric oxide synthase Geriatr. Gerontol. Int. 11 2011 143 156
-
(2011)
Geriatr. Gerontol. Int.
, vol.11
, pp. 143-156
-
-
Shinmura, K.1
-
334
-
-
67650659852
-
Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: Role of circulating factors and SIRT1
-
A. Csiszar, N. Labinskyy, R. Jimenez, J.T. Pinto, P. Ballabh, G. Losonczy, K.J. Pearson, R. de Cabo, and Z. Ungvari Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: role of circulating factors and SIRT1 Mech. Ageing Dev. 130 2009 518 527
-
(2009)
Mech. Ageing Dev.
, vol.130
, pp. 518-527
-
-
Csiszar, A.1
Labinskyy, N.2
Jimenez, R.3
Pinto, J.T.4
Ballabh, P.5
Losonczy, G.6
Pearson, K.J.7
De Cabo, R.8
Ungvari, Z.9
-
335
-
-
77957820976
-
Caloric restriction improves endothelial dysfunction during vascular aging: Effects on nitric oxide synthase isoforms and oxidative stress in rat aorta
-
M. Zanetti, G. Gortan Cappellari, I. Burekovic, R. Barazzoni, M. Stebel, and G. Guarnieri Caloric restriction improves endothelial dysfunction during vascular aging: effects on nitric oxide synthase isoforms and oxidative stress in rat aorta Exp. Gerontol. 45 2010 848 855
-
(2010)
Exp. Gerontol.
, vol.45
, pp. 848-855
-
-
Zanetti, M.1
Gortan Cappellari, G.2
Burekovic, I.3
Barazzoni, R.4
Stebel, M.5
Guarnieri, G.6
-
336
-
-
33947659941
-
Differential expressions of antioxidant status in aging rats: The role of transcriptional factor Nrf2 and MAPK signaling pathway
-
P.H. Shih, and G.C. Yen Differential expressions of antioxidant status in aging rats: the role of transcriptional factor Nrf2 and MAPK signaling pathway Biogerontology 8 2007 71 80
-
(2007)
Biogerontology
, vol.8
, pp. 71-80
-
-
Shih, P.H.1
Yen, G.C.2
-
337
-
-
34249891333
-
Two neurons mediate diet-restriction-induced longevity in C elegans
-
DOI 10.1038/nature05904, PII NATURE05904
-
N.A. Bishop, and L. Guarente Two neurons mediate diet-restriction-induced longevity in C. elegans Nature 447 2007 545 549 (Pubitemid 46868049)
-
(2007)
Nature
, vol.447
, Issue.7144
, pp. 545-549
-
-
Bishop, N.A.1
Guarente, L.2
-
338
-
-
40649108843
-
Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction
-
DOI 10.1073/pnas.0712162105
-
K.J. Pearson, K.N. Lewis, N.L. Price, J.W. Chang, E. Perez, M.V. Cascajo, K.L. Tamashiro, S. Poosala, A. Csiszar, Z. Ungvari, T.W. Kensler, M. Yamamoto, J.M. Egan, D.L. Longo, D.K. Ingram, P. Navas, and R. de Cabo Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction Proc. Natl. Acad. Sci. USA 105 2008 2325 2330 (Pubitemid 351520512)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.7
, pp. 2325-2330
-
-
Pearson, K.J.1
Lewis, K.N.2
Price, N.L.3
Chang, J.W.4
Perez, E.5
Cascajo, M.V.6
Tamashiro, K.L.7
Poosala, S.8
Csiszar, A.9
Ungvari, Z.10
Kensler, T.W.11
Yamamoto, M.12
Egan, J.M.13
Longo, D.L.14
Ingram, D.K.15
Navas, P.16
De Cabo, R.17
-
339
-
-
77649311383
-
Metformin induces a dietary restriction-like state and the oxidative stress response to extend C elegans Healthspan via AMPK, LKB1, and SKN-1
-
B. Onken, and M. Driscoll Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1 PLoS One 5 2010 e8758
-
(2010)
PLoS One
, vol.5
, pp. 8758
-
-
Onken, B.1
Driscoll, M.2
-
340
-
-
5644267729
-
Vascular aging: Molecular modulation of the prostanoid cascade by calorie restriction
-
J.W. Kim, Y. Zou, S. Yoon, J.H. Lee, Y.K. Kim, B.P. Yu, and H.Y. Chung Vascular aging: molecular modulation of the prostanoid cascade by calorie restriction J. Gerontol. A Biol. Sci. Med. Sci 59 2004 B876 B885
-
(2004)
J. Gerontol. A Biol. Sci. Med. Sci
, vol.59
-
-
Kim, J.W.1
Zou, Y.2
Yoon, S.3
Lee, J.H.4
Kim, Y.K.5
Yu, B.P.6
Chung, H.Y.7
-
341
-
-
1442265690
-
Alteration of soluble adhesion molecules during aging and their modulation by calorie restriction
-
Y. Zou, K.J. Jung, J.W. Kim, B.P. Yu, and H.Y. Chung Alteration of soluble adhesion molecules during aging and their modulation by calorie restriction FASEB J 18 2004 320 322
-
(2004)
FASEB J
, vol.18
, pp. 320-322
-
-
Zou, Y.1
Jung, K.J.2
Kim, J.W.3
Yu, B.P.4
Chung, H.Y.5
-
342
-
-
40949142846
-
Mechanisms underlying caloric restriction and lifespan regulation: Implications for vascular aging
-
Z. Ungvari, C. Parrado-Fernandez, A. Csiszar, and R de Cabo.Mechanisms underlying caloric restriction and lifespan regulation: implications for vascular aging Circ. Res. 102 2008 519 528
-
(2008)
Circ. Res.
, vol.102
, pp. 519-528
-
-
Ungvari, Z.1
Parrado-Fernandez, C.2
Csiszar, A.3
De Cabo, R.4
-
343
-
-
0029146956
-
A prospective study of consumption of carotenoids in fruits and vegetables and decreased cardiovascular mortality in the elderly
-
J.M. Gaziano, J.E. Manson, L.G. Branch, G.A. Colditz, W.C. Willett, and J.E. Buring A prospective study of consumption of carotenoids in fruits and vegetables and decreased cardiovascular mortality in the elderly Ann. Epidemiol. 5 1995 255 260
-
(1995)
Ann. Epidemiol.
, vol.5
, pp. 255-260
-
-
Gaziano, J.M.1
Manson, J.E.2
Branch, L.G.3
Colditz, G.A.4
Willett, W.C.5
Buring, J.E.6
-
344
-
-
0032899706
-
Dietary antioxidants and risk of myocardial infarction in the elderly: The Rotterdam Study
-
K. Klipstein-Grobusch, J.M. Geleijnse, J.H. den Breeijen, H. Boeing, A. Hofman, D.E. Grobbee, and J.C. Witteman Dietary antioxidants and risk of myocardial infarction in the elderly: the Rotterdam Study Am. J. Clin. Nutr. 69 1999 261 266 (Pubitemid 29065549)
-
(1999)
American Journal of Clinical Nutrition
, vol.69
, Issue.2
, pp. 261-266
-
-
Klipstein-Grobusch, K.1
Geleijnse, J.M.2
Den Breeijen, J.H.3
Boeing, H.4
Hofman, A.5
Grobbee, D.E.6
Witteman, J.C.M.7
-
345
-
-
0642310641
-
Antioxidant vitamins and mortality in older persons: Findings from the nutrition add-on study to the Medical Research Council Trial of Assessment and Management of Older People in the Community
-
A.E. Fletcher, E. Breeze, and P.S. Shetty Antioxidant vitamins and mortality in older persons: findings from the nutrition add-on study to the Medical Research Council Trial of Assessment and Management of Older People in the Community Am. J. Clin. Nutr 78 2003 999 1010 (Pubitemid 39663478)
-
(2003)
American Journal of Clinical Nutrition
, vol.78
, Issue.5
, pp. 999-1010
-
-
Fletcher, A.E.1
Breeze, E.2
Shetty, P.S.3
-
346
-
-
0030013268
-
Vitamin E and vitamin C supplement use and risk of all-cause and coronary heart disease mortality in older persons: The Established Populations for Epidemiologic Studies of the Elderly
-
K.G. Losonczy, T.B. Harris, and R.J. Havlik Vitamin E and vitamin C supplement use and risk of all-cause and coronary heart disease mortality in older persons: the Established Populations for Epidemiologic Studies of the Elderly Am. J. Clin. Nutr 64 1996 190 196 (Pubitemid 26250838)
-
(1996)
American Journal of Clinical Nutrition
, vol.64
, Issue.2
, pp. 190-196
-
-
Losonczy, K.G.1
Harris, T.B.2
Havlik, R.J.3
-
347
-
-
43049159738
-
Antioxidants in cardiovascular health and disease: Key lessons from epidemiologic studies
-
B.J. Willcox, J.D. Curb, and B.L. Rodriguez Antioxidants in cardiovascular health and disease: key lessons from epidemiologic studies Am. J. Cardiol. 101 2008 75D 86D
-
(2008)
Am. J. Cardiol.
, vol.101
-
-
Willcox, B.J.1
Curb, J.D.2
Rodriguez, B.L.3
-
348
-
-
84862786829
-
Acute reversal of endothelial dysfunction in the elderly after antioxidant consumption
-
D.W. Wray, S.K. Nishiyama, R.A. Harris, J. Zhao, J. McDaniel, A.S. Fjeldstad, M.A. Witman, S.J. Ives, Z. Barrett-O'Keefe, and R.S. Richardson Acute reversal of endothelial dysfunction in the elderly after antioxidant consumption Hypertension 59 2012 818 824
-
(2012)
Hypertension
, vol.59
, pp. 818-824
-
-
Wray, D.W.1
Nishiyama, S.K.2
Harris, R.A.3
Zhao, J.4
McDaniel, J.5
Fjeldstad, A.S.6
Witman, M.A.7
Ives, S.J.8
Barrett-O'Keefe, Z.9
Richardson, R.S.10
-
349
-
-
35648950423
-
High-dose ascorbic acid infusion abolishes chronic vasoconstriction and restores resting leg blood flow in healthy older men
-
DOI 10.1152/japplphysiol.00533.2007
-
K.L. Jablonski, D.R. Seals, I. Eskurza, K.D. Monahan, and A.J. Donato High-dose ascorbic acid infusion abolishes chronic vasoconstriction and restores resting leg blood flow in healthy older men J. Appl. Physiol. 103 2007 1715 1721 (Pubitemid 350033857)
-
(2007)
Journal of Applied Physiology
, vol.103
, Issue.5
, pp. 1715-1721
-
-
Jablonski, K.L.1
Seals, D.R.2
Eskurza, I.3
Monahan, K.D.4
Donato, A.J.5
-
350
-
-
78851468985
-
Anti-inflammatory effects of resveratrol: Possible role in prevention of age-related cardiovascular disease
-
A. Csiszar Anti-inflammatory effects of resveratrol: possible role in prevention of age-related cardiovascular disease Ann. N. Y. Acad. Sci. 1215 2011 117 122
-
(2011)
Ann. N. Y. Acad. Sci.
, vol.1215
, pp. 117-122
-
-
Csiszar, A.1
-
351
-
-
48349144852
-
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span
-
K.J. Pearson, J.A. Baur, K.N. Lewis, L. Peshkin, N.L. Price, N. Labinskyy, W.R. Swindell, D. Kamara, R.K. Minor, E. Perez, H.A. Jamieson, Y. Zhang, S.R. Dunn, K. Sharma, N. Pleshko, L.A. Woollett, A. Csiszar, Y. Ikeno, D. Le Couteur, P.J. Elliott, K.G. Becker, P. Navas, D.K. Ingram, N.S. Wolf, Z. Ungvari, D.A. Sinclair, and R. de Cabo Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span Cell Metab. 8 2008 157 168
-
(2008)
Cell Metab.
, vol.8
, pp. 157-168
-
-
Pearson, K.J.1
Baur, J.A.2
Lewis, K.N.3
Peshkin, L.4
Price, N.L.5
Labinskyy, N.6
Swindell, W.R.7
Kamara, D.8
Minor, R.K.9
Perez, E.10
Jamieson, H.A.11
Zhang, Y.12
Dunn, S.R.13
Sharma, K.14
Pleshko, N.15
Woollett, L.A.16
Csiszar, A.17
Ikeno, Y.18
Le Couteur, D.19
Elliott, P.J.20
Becker, K.G.21
Navas, P.22
Ingram, D.K.23
Wolf, N.S.24
Ungvari, Z.25
Sinclair, D.A.26
De Cabo, R.27
more..
-
352
-
-
84861865625
-
Age-associated proinflammatory secretory phenotype in vascular smooth muscle cells from the non-human primate Macaca mulatta: Reversal by resveratrol treatment
-
A. Csiszar, D. Sosnowska, M. Wang, E.G. Lakatta, W.E. Sonntag, and Z. Ungvari Age-associated proinflammatory secretory phenotype in vascular smooth muscle cells from the non-human primate Macaca mulatta: reversal by resveratrol treatment J. Gerontol. A Biol. Sci. Med. Sci 67 2012 811 820
-
(2012)
J. Gerontol. A Biol. Sci. Med. Sci
, vol.67
, pp. 811-820
-
-
Csiszar, A.1
Sosnowska, D.2
Wang, M.3
Lakatta, E.G.4
Sonntag, W.E.5
Ungvari, Z.6
-
353
-
-
77958559652
-
Resveratrol protects human endothelium from H(2)O(2)-induced oxidative stress and senescence via SirT1 activation
-
C.L. Kao, L.K. Chen, Y.L. Chang, M.C. Yung, C.C. Hsu, Y.C. Chen, W.L. Lo, S.J. Chen, H.H. Ku, and S.J. Hwang Resveratrol protects human endothelium from H(2)O(2)-induced oxidative stress and senescence via SirT1 activation J. Atheroscler. Thromb. 17 2010 970 979
-
(2010)
J. Atheroscler. Thromb.
, vol.17
, pp. 970-979
-
-
Kao, C.L.1
Chen, L.K.2
Chang, Y.L.3
Yung, M.C.4
Hsu, C.C.5
Chen, Y.C.6
Lo, W.L.7
Chen, S.J.8
Ku, H.H.9
Hwang, S.J.10
-
354
-
-
84865383114
-
Red wine and equivalent oral pharmacological doses of resveratrol delay vascular aging but do not extend life span in rats
-
P.L. da Luz, L. Tanaka, P.C. Brum, P.M. Dourado, D. Favarato, J.E. Krieger, and F.R. Laurindo Red wine and equivalent oral pharmacological doses of resveratrol delay vascular aging but do not extend life span in rats Atherosclerosis 224 2012 136 142
-
(2012)
Atherosclerosis
, vol.224
, pp. 136-142
-
-
Da Luz, P.L.1
Tanaka, L.2
Brum, P.C.3
Dourado, P.M.4
Favarato, D.5
Krieger, J.E.6
Laurindo, F.R.7
-
355
-
-
0029925181
-
Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)
-
DOI 10.1016/S0140-6736(96)90866-1
-
N.G. Stephens, A. Parsons, P.M. Schofield, F. Kelly, K. Cheeseman, and M.J. Mitchinson Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS) Lancet 347 1996 781 786 (Pubitemid 26091640)
-
(1996)
Lancet
, vol.347
, Issue.9004
, pp. 781-786
-
-
Stephens, N.G.1
Parsons, A.2
Schofield, P.M.3
Kelly, F.4
Cheeseman, K.5
Mitchinson, M.J.6
Brown, M.J.7
-
356
-
-
0037840165
-
Use of antioxidant vitamins for the prevention of cardiovascular disease: Meta-analysis of randomised trials
-
DOI 10.1016/S0140-6736(03)13637-9
-
D.P. Vivekananthan, M.S. Penn, S.K. Sapp, A. Hsu, and E.J. Topol Use of antioxidant vitamins for the prevention of cardiovascular disease: meta-analysis of randomised trials Lancet 361 2003 2017 2023 (Pubitemid 36695043)
-
(2003)
Lancet
, vol.361
, Issue.9374
, pp. 2017-2023
-
-
Vivekananthan, D.P.1
Penn, M.S.2
Sapp, S.K.3
Hsu, A.4
Topol, E.J.5
-
357
-
-
33847378451
-
Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: Systematic review and meta-analysis
-
DOI 10.1001/jama.297.8.842
-
G. Bjelakovic, D. Nikolova, L.L. Gluud, R.G. Simonetti, and C. Gluud Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis JAMA 297 2007 842 857 (Pubitemid 46333949)
-
(2007)
Journal of the American Medical Association
, vol.297
, Issue.8
, pp. 842-857
-
-
Bjelakovic, G.1
Nikolova, D.2
Gluud, L.L.3
Simonetti, R.G.4
Gluud, C.5
-
358
-
-
84875787136
-
Primary prevention of cardiovascular disease with a Mediterranean diet
-
R. Estruch, E. Ros, J. Salas-Salvado, M.I. Covas, D. Corella, F. Aros, E. Gomez-Gracia, V. Ruiz-Gutierrez, M. Fiol, J. Lapetra, R.M. Lamuela-Raventos, L. Serra-Majem, X. Pinto, J. Basora, M.A. Munoz, J.V. Sorli, J.A. Martinez, and M.A. Martinez-Gonzalez Primary prevention of cardiovascular disease with a Mediterranean diet N. Engl. J. Med. 368 2013 1279 1290
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 1279-1290
-
-
Estruch, R.1
Ros, E.2
Salas-Salvado, J.3
Covas, M.I.4
Corella, D.5
Aros, F.6
Gomez-Gracia, E.7
Ruiz-Gutierrez, V.8
Fiol, M.9
Lapetra, J.10
Lamuela-Raventos, R.M.11
Serra-Majem, L.12
Pinto, X.13
Basora, J.14
Munoz, M.A.15
Sorli, J.V.16
Martinez, J.A.17
Martinez-Gonzalez, M.A.18
-
359
-
-
0036774130
-
Effects of a 'healthy' diet and of acute and long-term vitamin C on vascular function in healthy older subjects
-
DOI 10.1016/S0008-6363(02)00514-X, PII S000863630200514X
-
N. Singh, J. Graves, P.D. Taylor, R.J. MacAllister, and D.R. Singer Effects of a 'healthy' diet and of acute and long-term vitamin C on vascular function in healthy older subjects Cardiovasc. Res. 56 2002 118 125 (Pubitemid 35247808)
-
(2002)
Cardiovascular Research
, vol.56
, Issue.1
, pp. 118-125
-
-
Singh, N.1
Graves, J.2
Taylor, P.D.3
MacAllister, R.J.4
Singer, D.R.J.5
-
360
-
-
84874704861
-
Mediterranean diet- and exercise-induced improvement in age-dependent vascular activity
-
M. Klonizakis, A. Alkhatib, G. Middleton, and M.F. Smith Mediterranean diet- and exercise-induced improvement in age-dependent vascular activity Clin. Sci. (Lond.) 124 2013 579 587
-
(2013)
Clin. Sci. (Lond.)
, vol.124
, pp. 579-587
-
-
Klonizakis, M.1
Alkhatib, A.2
Middleton, G.3
Smith, M.F.4
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