Endothelial regulation of vasomotion in ApoE-deficient mice: Implications for interactions between peroxynitrite and tetrahydrobiopterin

Circulation

Volumn 103, Issue 9, 2001, Pages 1282-1288

  Laursen, Jørn Bech ^a,c   Somers, Mark ^a   Kurz, Sabine ^a   McCann, Louise ^a   Warnholtz, Ascan ^a   Freeman, Bruce A ^b   Tarpey, Margaret ^b   Fukai, Tohru ^a   Harrison, David G ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c University of Copenhagen   (Denmark)

Author keywords

Endothelium; Genes; Vessels

Indexed keywords

APOLIPOPROTEIN E; EBSELEN; HYDROGEN PEROXIDE; LIPOSOME; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PEROXYNITRITE; SEPIAPTERIN; SUPEROXIDE DISMUTASE; TETRAHYDROBIOPTERIN; URIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; BLOOD VESSEL REACTIVITY; CHEMOLUMINESCENCE; ENDOTHELIUM CELL; ENZYME ACTIVITY; FEMALE; IMMUNOHISTOCHEMISTRY; LIPOPROTEIN DEFICIENCY; MALE; MOUSE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; SPECTROPHOTOMETRY; STATISTICAL ANALYSIS; VASODILATATION; WESTERN BLOTTING;

EID: 0035814951     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.103.9.1282     Document Type: Article

References (29)

1. Hypercholesterolemia increases endothelial superoxide anion production
2. Superoxide and peroxynitrite in atherosclerosis
3. Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry
4. Cellular and molecular mechanisms of endothelial cell dysfunction
5. Tetrahydrobiopterin restores endothelial function in hypercholesterolemia
6. 2+/calmodulin-dependent and tetrahydrobiopterin regulatory process
7. Superoxide generation by endothelial nitric oxide synthase: The influence of cofactors
8. Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion
9. Tetrahydrobiopterin and dysfunction of endothelial nitric oxide synthase in coronary arteries
10. Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells
11. A role of superoxide in angiotensin II-but not catecholamine-induced hypertension
12. Peroxynitrite oxidation of sulfhydryls: The cytotoxic potential of superoxide and nitric oxide
13. Protein expression, vascular reactivity and soluble guanylate cyclase activity in mice lacking the endothelial cell nitric oxide synthase: Contributions of NOS isoforms to blood pressure and heart rate control
14. Regulation of the vascular extracellular superoxide dismutase by nitric oxide and exercise training
15. Validation of lucigenin as a chemiluminiscent probe to monitor vascular superoxide as well as basal vascular nitric oxide production
16. Validation of lucigenin (bis-N-methylacridinium) as a chemilumigenic probe for detecting superoxide anion radical production by enzymatic and cellular systems
17. Peroxynitrite-induced luminol chemiluminescence
18. The reaction of ebselen with peroxynitrite
19. Uric acid, a natural scavenger of peroxynitrite, in experimental allergic encephalomyelitis and multiple sclerosis
20. Protection agaisnt peroxynitrite-dependent tyrosine nitration and alpha 1-antiproteinase inactivation by ascorbic acid: A comparison with other biological antioxidants
21. On the chemical reactivity of superoxide
22. Oxidation of tetrahydrobiopterin by peroxynitrite: Implications for vascular endothelial function
23. The pecking order of free radicals and antioxidants: Lipid peroxidation, alpha-tocopherol, and ascorbate
24. Action of biologically-relevant oxidizing species upon uric acid: Identification of uric acid oxidation products
25. Crystal structure of constitutive endothelial nitric oxide synthase: A paradigm for pterin function involving a novel metal center
26. Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression by hydrogen peroxide
27. Cytokines stimulate GTP cyclohydrolase I gene expression in cultured human umbilical vein endothelial cells