Increased aortic calpain-1 activity mediates age-associated angiotensin II signaling of vascular smooth muscle cells

PLoS ONE

Volumn 3, Issue 5, 2008, Pages

  Jiang, Liqun ^a   Wang, Mingyi ^a   Zhang, Jing ^a   Monticone, Robert E ^a   Telljohann, Richard ^a   Spinetti, Gaia ^b   Pintus, Gianfranco ^c   Lakatta, Edward G ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b IRCCS MULTIMEDICA   (Italy)

^c UNIVERSITY OF SASSARI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ANGIOTENSIN II; CALPAIN 1; CALPASTATIN; GELATINASE A; ILOMASTAT; VIMENTIN; CALPAIN;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY LABELING; AORTA; AORTA WALL; ARTERY WALL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; EX VIVO STUDY; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; IN VITRO STUDY; IN VIVO STUDY; LEUKOCYTE MIGRATION INHIBITION TEST; MALE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; RNA TRANSLATION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; UPREGULATION; VASCULAR RING; VASCULAR SMOOTH MUSCLE; ANIMAL; CYTOLOGY; ENZYMOLOGY; FISCHER 344 RAT; METABOLISM; PHYSIOLOGY; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

RATTUS;

AGING; ANGIOTENSIN II; ANIMALS; AORTA; CALPAIN; MALE; MATRIX METALLOPROTEINASE 2; MUSCLE, SMOOTH, VASCULAR; PROTEIN BIOSYNTHESIS; RATS; RATS, INBRED F344; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

EID: 48249108338     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0002231     Document Type: Article

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