Exercise training attenuates ageing-induced BKCa channel downregulation in rat coronary arteries

Experimental Physiology

Volumn 95, Issue 6, 2010, Pages 746-755

  Albarwani, Sulayma ^a   Al Siyabi, Sultan ^a   Baomar, Hajar ^a   Hassan, Mohammed O ^a  

^a SULTAN QABOOS UNIVERSITY   (Oman)

Author keywords

[No Author keywords available]

Indexed keywords

IBERIOTOXIN; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNIT; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL BETA SUBUNIT; POTASSIUM ION; SEROTONIN;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY MUSCLE; ARTERY TONE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY; CORONARY ARTERY CONSTRICTION; DOWN REGULATION; ELECTROPHYSIOLOGY; EXERCISE; FISCHER 344 RAT; MALE; MYOGRAPHY; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PROTEIN EXPRESSION; RAT; REST; SMOOTH MUSCLE FIBER; TREADMILL EXERCISE; WESTERN BLOTTING;

EID: 77952506392     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/expphysiol.2009.051250     Document Type: Article

References (48)

1. + channels in rat small cerebral arteries: molecular identity of the functional channels. J Physiol 551, 751 763.
2. 1 subunit in genetic hypertension. Circ Res 93, 965 971.
3. Betts LC Kozlowski RZ (2000). Electrophysiological effects of endothelin-1 and their relationship to contraction in rat renal arterial smooth muscle. Br J Pharmacol 130, 787 796.
4. Blanco-Centurion CA Shiromani PJ (2006). Beneficial effects of regular exercise on sleep in old F344 rats. Neurobiol Aging 27, 1859 1869.
5. Ca channels in metabolic syndrome. Am J Physiol Heart Circ Physiol 297, H1629 H1637.
6. Bowles DK, Hu Q, Laughlin MH Sturek M (1998a). Exercise training increases L-type calcium current density in coronary smooth muscle. Am J Physiol Heart Circ Physiol 275, H2159 H2169.
7. +-channel contribution to regulation of coronary arterial tone. J Appl Physiol 84, 1225 1233.
8. Brayden JE Nelson MT (1992). Regulation of arterial tone by activation of calcium-dependent potassium channels. Science 256, 532 535.
9. Brenner R, Peréz GJ, Bonev AD, Eckman DM, Kosek JC, Wiler SW, Patterson AJ, Nelson MT Aldrich RW (2000). Vasoregulation by the β1 subunit of the calcium-activated potassium channel. Nature 407, 870 876.
10. + channels from arteries of Type 2 diabetic Zucker diabetic fatty rats. Am J Physiol Heart Circ Physiol 290, H1520 H1527.
11. Chandrashekhar Y Anand IS (1991). Exercise as a coronary protective factor. Am Heart J 122, 1723 1739.
12. 2+ sensitivity. J Gen Physiol 116, 411 432.
13. DeSouza CA, Shapiro LF, Clevenger CM, Dinenno FA, Monahan KD, Tanaka H Seals DR (2000). Regular aerobic exercise prevents and restores age-related declines in endothelium-dependent vasodilation in healthy men. Circulation 102, 1351 1357.
14. Dick GM, Rossow CF, Smirnov S, Horowitz B Sanders KM (2001). Tamoxifen activates smooth muscle BK channels through the regulatory β1 subunit. J Biol Chem 276, 34594 34599.
15. Donato AJ, Gano LB, Eskurza I, Silver AE, Gates PE, Jablonski K Seals DR (2009). Vascular endothelial dysfunction with aging: endothelin-1 and endothelial nitric oxide synthase. Am J Physiol Heart Circ Physiol 297, H425 H432.
16. Duncker DJ Bache RJ (2008). Regulation of coronary blood flow during exercise. Physiol Rev 88, 1009 1086.
17. Fletcher GF, Balady G, Blair SN, Blumenthal J, Caspersen C, Chaitman B, Epstein S, Sivarajan Froelicher ES, Froelicher VF, Pina IL Pollock ML (1996). Statement on exercise: benefits and recommendations for physical activity programs for all Americans. A statement for health professionals by the Committee on Exercise and Cardiac Rehabilitation of the Council on Clinical Cardiology, American Heart Association. Circulation 94, 857 862.
18. Garcia ML, Hanner M, Knaus HG, Slaughter R Kaczorowski GJ (1999). Scorpion toxins as tools for studying potassium channels. Methods Enzymol 294, 624 639.
19. 2+ channels in arterial smooth muscle cells. Kidney Blood Press Res 20, 355 371.
20. Halpern W, Mulvany MJ Warshaw DM (1978). Mechanical properties of smooth muscle cells in the walls of arterial resistance vessels. J Physiol 275, 85 101.
21. 2+ accumulation. J Physiol 528, 435 445.
22. Ca channels is age-dependent. Eur J Pharmacol 578, 108 113.
23. Ca channel gating by endogenous signaling molecules. Physiology (Bethesda) 24, 26 35.
24. Ishida S, Hamasaki S, Kamekou M, Yoshitama T, Nakano F, Yoshikawa A, Kataoka T, Saihara K, Minagoe S Tei C (2003). Advancing age is associated with diminished vascular remodeling and impaired vasodilation in resistance coronary arteries. Coron Artery Dis 14, 443 449.
25. + channel isoform. J Neurophysiol 97, 3508 3516.
26. Korzick DH, Muller-Delp JM, Dougherty P, Heaps CL, Bowles DK Krick KK (2005). Exaggerated coronary vasoreactivity to endothelin-1 in aged rats: role of protein kinase C. Cardiovasc Res 66, 384 392.
27. Laughlin MH Muller JM (1998). Vasoconstrictor responses of coronary resistance arteries in exercise-trained pigs. J Appl Physiol 84, 884 889.
28. Laughlin MH, Pollock JS, Amann JF, Hollis ML, Woodman CR Price EM (2001). Training induces nonuniform increases in eNOS content along the coronary arterial tree. J Appl Physiol 90, 501 510.
29. Maeda S, Sugawara J, Yoshizawa M, Otsuki T, Shimojo N, Jesmin S, Ajisaka R, Miyauchi T Tanaka H (2009). Involvement of endothelin-1 in habitual exercise-induced increase in arterial compliance. Acta Physiol (Oxf) 196, 223 229.
30. + channels in coronary smooth muscle during aging. Circ Res 88, 210 216.
31. 1-subunit and altered vasoregulation in hypoxia. Circulation 112, 309 315.
32. Nelson MT, Patlak JB, Worley JF Standen NB (1990). Calcium channels, potassium channels, and voltage dependence of arterial smooth muscle tone. Am J Physiol Cell Physiol 259, C3 C18.
33. Nelson MT Quayle JM (1995). Physiological roles and properties of potassium channels in arterial smooth muscle. Am J Physiol Cell Physiol 268, C799 C822.
34. Nishimaru K, Eghbali M, Lu R, Marijic J, Stefani E Toro L (2004). Functional and molecular evidence of MaxiK channel β1 subunit decrease with coronary artery ageing in the rat. J Physiol 559, 849 862.
35. Parker JL, Oltman CL, Muller JM, Myers PR, Adams HR Laughlin MH (1994). Effects of exercise training on regulation of tone in coronary arteries and arterioles. Med Sci Sports Exerc 26, 1252 1261.
36. Ca channel in smooth muscle. Trends Pharmacol Sci 22, 505 512.
37. Sessa WC, Pritchard K, Seyedi N, Wang J Hintze TH (1994). Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression. Circ Res 74, 349 353.
38. Shipley RD Muller-Delp JM (2005). Aging decreases vasoconstrictor responses of coronary resistance arterioles through endothelium-dependent mechanisms. Cardiovasc Res 66, 374 383.
39. Stehno-Bittel L, Laughlin MH Sturek M (1991). Exercise training depletes sarcoplasmic reticulum calcium in coronary smooth muscle. J Appl Physiol 71, 1764 1773.
40. Stewart KJ (2005). Physical activity and aging. Ann N Y Acad Sci 1055, 193 206.
41. Tanaka S, Tamaya N, Matsuzawa K Miyaishi O (2000). Differences in survivability among F344 rats. Exp Anim 49, 141 145.
42. Tanaka Y, Koike K Toro L (2004). MaxiK channel roles in blood vessel relaxations induced by endothelium-derived relaxing factors and their molecular mechanisms. J Smooth Muscle Res 40, 125 153.
43. Ca channels in human coronary smooth muscle: predominant α + β subunit complexes. J Physiol 502, 545 557.
44. Van Guilder GP, Westby CM, Greiner JJ, Stauffer BL DeSouza CA (2007). Endothelin-1 vasoconstrictor tone increases with age in healthy men but can be reduced by regular aerobic exercise. Hypertension 50, 403 409.
45. + channels: a transmembrane β-subunit homolog. Proc Natl Acad Sci USA 96, 4137 4142.
46. Wei JY, Li Y Ragland J (1987). Effect of exercise training on resting blood pressure and heart rate in adult and aged rats. J Gerontol 42, 11 16.
47. Yildiz O (2007). Vascular smooth muscle and endothelial functions in aging. Ann N Y Acad Sci 1100, 353 360.
48. Ziada AM, Hassan MO, Tahlilkar KI Inuwa IM (2005). Long-term exercise training and angiotensin-converting enzyme inhibition differentially enhance myocardial capillarization in the spontaneously hypertensive rat. J Hypertens 23, 1233 1240.