PPARγ regulates hypoxia-induced Nox4 expression in human pulmonary artery smooth muscle cells through NF-κB

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 299, Issue 4, 2010, Pages

  Lu, Xianghuai ^a   Murphy, Tamara C ^a   Nanes, Mark S ^a   Hart, C Michael ^a  

^a EMORY UNIVERSITY   (United States)

Author keywords

Nuclear factor B; Peroxisome proliferator activated receptor

Indexed keywords

HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN P50; PROTEIN SUBUNIT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; ROSIGLITAZONE; SMALL INTERFERING RNA; SUPEROXIDE; SYNAPTOTAGMIN I; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIDIABETIC AGENT; NOX4 PROTEIN, HUMAN; OXYGEN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY MUSCLE; ARTICLE; BINDING KINETICS; BLOOD VESSEL WALL; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HYPOXIA; INHIBITION KINETICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PULMONARY HYPERTENSION; REGULATORY MECHANISM; SMOOTH MUSCLE FIBER; TISSUE REPAIR; UPREGULATION; ANIMAL; ANOXIA; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; GENETICS; METABOLISM; PATHOLOGY; PULMONARY ARTERY;

ANIMALS; ANOXIA; CELL PROLIFERATION; CELLS, CULTURED; HUMANS; HYDROGEN PEROXIDE; HYPOGLYCEMIC AGENTS; MICE; MYOCYTES, SMOOTH MUSCLE; NADPH OXIDASE; NF-KAPPA B; OXYGEN; PPAR GAMMA; PROMOTER REGIONS, GENETIC; PULMONARY ARTERY; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; THIAZOLIDINEDIONES;

EID: 77957350902     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00090.2010     Document Type: Article

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