Synergistic effect of HIF-1α gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 48, 2009, Pages 20399-20404

  Rey, Sergio ^a   Lee, KangAe ^a   Wang, C Joanne ^b   Gupta, Kshitiz ^b   Chen, Shaoping ^a   McMillan, Alexandra ^a   Bhise, Nupura ^b   Levchenko, Andre ^b   Semenza, Gregg L ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Johns Hopkins University   (United States)

Author keywords

Angiogenesis; Cell therapy; Hypoxia; Prolyl hydroxylation

Indexed keywords

BETA2 INTEGRIN; BLOCKING ANTIBODY; DIGOXIN; ENZYME INHIBITOR; HYPOXIA INDUCIBLE FACTOR 1;

ANGIOGENIC GENE THERAPY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY LIGATION; ARTICLE; BONE MARROW CELL; CELL HOMING; CELL SURFACE; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMORAL ARTERY; HUMAN; LIMB ISCHEMIA; LIMB SALVAGE; MOTOR PERFORMANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TISSUE PERFUSION;

ADENOVIRIDAE; AGE FACTORS; AMINO ACIDS, DICARBOXYLIC; ANGIOGENESIS INDUCING AGENTS; ANIMALS; BONE MARROW TRANSPLANTATION; CELL ADHESION; CELL MOVEMENT; FEMORAL ARTERY; FLOW CYTOMETRY; GENE THERAPY; HINDLIMB; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INJECTIONS, INTRAMUSCULAR; ISCHEMIA; LIGATION; MICE; PROCOLLAGEN-PROLINE DIOXYGENASE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

ADENOVIRIDAE; LENTIVIRUS; MUS;

EID: 73949085704     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0911921106     Document Type: Article

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