Therapeutic targeting of mitochondrial superoxide in hypertension

Circulation Research

Volumn 107, Issue 1, 2010, Pages 106-116

  Dikalova, Anna E ^a   Bikineyeva, Alfiya T ^a   Budzyn, Klaudia ^a   Nazarewicz, Rafal R ^a   McCann, Louise ^a   Lewis, William ^a   Harrison, David G ^a   Dikalov, Sergey I ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Hypertension; Mitochondria; Mitochondrial targeted antioxidant; Superoxide

Indexed keywords

( 2 ( 2,2,6,6 TETRAMETHYLPIPERIDIN 1 OXYL 4 YLAMINO) 2 OXOETHYL)TRIPHENYLPHOSPHONIUM; ANGIOTENSIN II; ANGIOTENSIN II ANTAGONIST; DEOXYCORTICOSTERONE ACETATE; MANGANESE SUPEROXIDE DISMUTASE; NITRIC OXIDE; OXYGEN; PIPERIDINE DERIVATIVE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SMALL INTERFERING RNA; SUPEROXIDE; TEMPOL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; ATTENUATION; BIOAVAILABILITY; BLOOD PRESSURE; CONTROLLED STUDY; DRUG INFUSION; ENZYME ACTIVITY; ENZYME SYNTHESIS; GENE EXPRESSION; HEART MITOCHONDRION; HEART MUSCLE RELAXATION; HYPERTENSION; IN VIVO STUDY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN TARGETING; SCAVENGING SYSTEM; TRANSGENE; VASCULAR ENDOTHELIUM; VASODILATATION;

ANIMALS; ANTIOXIDANTS; CATTLE; CELLS, CULTURED; CYCLIC N-OXIDES; DRUG DELIVERY SYSTEMS; ENDOTHELIAL CELLS; HUMANS; HYPERTENSION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOCHONDRIA; SUPEROXIDE DISMUTASE; SUPEROXIDES;

EID: 77954698808     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.109.214601     Document Type: Article

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