메뉴 건너뛰기




Volumn 169, Issue 7, 2013, Pages 1486-1499

Endothelium-dependent hyperpolarization-related relaxations diminish with age in murine saphenous arteries of both sexes

Author keywords

EDH related responses; KCa2.3; KCa3.1; L NAME

Indexed keywords

1 [(2 CHLOROPHENYL)DIPHENYLMETHYL] 1H PYRAZOLE; 6, 7 DICHLORO 1H INDOLE 2,3 DIONE 3 OXIME; 6,10 DIAZA 3(1,3)8,(1,4) DIBENZENA 1,5(1,4) DIQUINOLINACYCLODECAPHANE; ACETYLCHOLINE; INDOMETACIN; INTERMEDIATE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; N(G) NITROARGININE METHYL ESTER; NAPHTHO[1,2 D]THIAZOL-2 YLAMINE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITROPRUSSIDE SODIUM; NS 309; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL STIMULATING AGENT; SKA 31; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; UNCLASSIFIED DRUG;

EID: 84880271033     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12175     Document Type: Article
Times cited : (26)

References (52)
  • 2
    • 0028220671 scopus 로고
    • Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle
    • Bolotina VM, Najibi S, Palacino JJ, Pagano PJ, Cohen RA, (1994). Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle. Nature 368: 850-853.
    • (1994) Nature , vol.368 , pp. 850-853
    • Bolotina, V.M.1    Najibi, S.2    Palacino, J.J.3    Pagano, P.J.4    Cohen, R.A.5
  • 3
    • 66349089328 scopus 로고    scopus 로고
    • Genetic deficit of SK3 and IK1 channels disrupts the endothelium-derived hyperpolarizing factor vasodilator pathway and causes hypertension
    • Brahler S, Kaistha A, Schmidt VJ, Wolfle SE, Busch C, Kaistha BP, et al. (2009). Genetic deficit of SK3 and IK1 channels disrupts the endothelium-derived hyperpolarizing factor vasodilator pathway and causes hypertension. Circulation 119: 2323-2332.
    • (2009) Circulation , vol.119 , pp. 2323-2332
    • Brahler, S.1    Kaistha, A.2    Schmidt, V.J.3    Wolfle, S.E.4    Busch, C.5    Kaistha, B.P.6
  • 5
    • 0141893558 scopus 로고    scopus 로고
    • Aged spontaneously hypertensive rats exhibit a selective loss of EDHF-mediated relaxation in the renal artery
    • Bussemaker E, Popp R, Fisslthaler B, Larson CM, Fleming I, Busse R, et al. (2003). Aged spontaneously hypertensive rats exhibit a selective loss of EDHF-mediated relaxation in the renal artery. Hypertension 42: 562-568.
    • (2003) Hypertension , vol.42 , pp. 562-568
    • Bussemaker, E.1    Popp, R.2    Fisslthaler, B.3    Larson, C.M.4    Fleming, I.5    Busse, R.6
  • 6
    • 0036186223 scopus 로고    scopus 로고
    • What is new in endothelium-derived hyperpolarizing factors?
    • Campbell WB, Gauthier KM, (2002). What is new in endothelium-derived hyperpolarizing factors? Curr Opin Nephrol Hypertens 11: 177-183.
    • (2002) Curr Opin Nephrol Hypertens , vol.11 , pp. 177-183
    • Campbell, W.B.1    Gauthier, K.M.2
  • 7
    • 0021354536 scopus 로고
    • Epidemiology of coronary heart disease: The Framingham study
    • Castelli WP, (1984). Epidemiology of coronary heart disease: the Framingham study. Am J Med 76 (2A): 4-12.
    • (1984) Am J Med , vol.76 , Issue.2 A , pp. 4-12
    • Castelli, W.P.1
  • 8
    • 79951970991 scopus 로고    scopus 로고
    • Endothelium-dependent vasodilation in human mesenteric artery is primarily mediated by myoendothelial gap junctions intermediate conductance calcium-activated K+ channel and nitric oxide
    • Chadha PS, Liu L, Rikard-Bell M, Senadheera S, Howitt L, Bertrand RL, et al. (2011). Endothelium-dependent vasodilation in human mesenteric artery is primarily mediated by myoendothelial gap junctions intermediate conductance calcium-activated K+ channel and nitric oxide. J Pharmacol Exp Ther 336: 701-708.
    • (2011) J Pharmacol Exp Ther , vol.336 , pp. 701-708
    • Chadha, P.S.1    Liu, L.2    Rikard-Bell, M.3    Senadheera, S.4    Howitt, L.5    Bertrand, R.L.6
  • 9
    • 81555229242 scopus 로고    scopus 로고
    • Pharmacological activation of KCa3.1/KCa2.3 channels produces endothelial hyperpolarization and lowers blood pressure in conscious dogs
    • Damkjaer M, Nielsen G, Bodendiek S, Staehr M, Gramsbergen JB, de Wit C, et al. (2012). Pharmacological activation of KCa3.1/KCa2.3 channels produces endothelial hyperpolarization and lowers blood pressure in conscious dogs. Br J Pharmacol 165: 223-234.
    • (2012) Br J Pharmacol , vol.165 , pp. 223-234
    • Damkjaer, M.1    Nielsen, G.2    Bodendiek, S.3    Staehr, M.4    Gramsbergen, J.B.5    De Wit, C.6
  • 10
    • 0034687139 scopus 로고    scopus 로고
    • Regular aerobic exercise prevents and restores age-related declines in endothelium-dependent vasodilation in healthy men
    • DeSouza CA, Shapiro LF, Clevenger CM, Dinenno FA, Monahan KD, Tanaka H, et al. (2000). Regular aerobic exercise prevents and restores age-related declines in endothelium-dependent vasodilation in healthy men. Circulation 102: 1351-1357.
    • (2000) Circulation , vol.102 , pp. 1351-1357
    • Desouza, C.A.1    Shapiro, L.F.2    Clevenger, C.M.3    Dinenno, F.A.4    Monahan, K.D.5    Tanaka, H.6
  • 11
    • 33845567347 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase activation leads to dilatory H2O2 production in mouse cerebral arteries
    • Drouin A, Thorin-Trescases N, Hamel E, Falck JR, Thorin E, (2007). Endothelial nitric oxide synthase activation leads to dilatory H2O2 production in mouse cerebral arteries. Cardiovasc Res 73: 73-81.
    • (2007) Cardiovasc Res , vol.73 , pp. 73-81
    • Drouin, A.1    Thorin-Trescases, N.2    Hamel, E.3    Falck, J.R.4    Thorin, E.5
  • 12
    • 77955292086 scopus 로고    scopus 로고
    • Endothelium-derived hyperpolarising factors and associated pathways: A synopsis
    • Edwards G, Feletou M, Weston AH, (2010). Endothelium-derived hyperpolarising factors and associated pathways: a synopsis. Pflugers Arch 459: 863-879.
    • (2010) Pflugers Arch , vol.459 , pp. 863-879
    • Edwards, G.1    Feletou, M.2    Weston, A.H.3
  • 13
    • 0027252930 scopus 로고
    • Effects of age on endothelium-dependent vasodilation of resistance coronary artery by acetylcholine in humans
    • Egashira K, Inou T, Hirooka Y, Kai H, Sugimachi M, Suzuki S, et al. (1993). Effects of age on endothelium-dependent vasodilation of resistance coronary artery by acetylcholine in humans. Circulation 88: 77-81.
    • (1993) Circulation , vol.88 , pp. 77-81
    • Egashira, K.1    Inou, T.2    Hirooka, Y.3    Kai, H.4    Sugimachi, M.5    Suzuki, S.6
  • 14
    • 0029962414 scopus 로고    scopus 로고
    • The vascular protective effects of estrogen
    • Farhat MY, Lavigne MC, Ramwell PW, (1996). The vascular protective effects of estrogen. FASEB J 10: 615-624.
    • (1996) FASEB J , vol.10 , pp. 615-624
    • Farhat, M.Y.1    Lavigne, M.C.2    Ramwell, P.W.3
  • 15
    • 0033377927 scopus 로고    scopus 로고
    • The third pathway: Endothelium-dependent hyperpolarization
    • Feletou M, Vanhoutte PM, (1999). The third pathway: endothelium-dependent hyperpolarization. J Physiol Pharmacol 50: 525-534.
    • (1999) J Physiol Pharmacol , vol.50 , pp. 525-534
    • Feletou, M.1    Vanhoutte, P.M.2
  • 17
    • 0027161927 scopus 로고
    • Age-related changes in endothelium-dependent hyperpolarization in the rat mesenteric artery
    • Fujii K, Ohmori S, Tominaga M, Abe I, Takata Y, Ohya Y, et al. (1993). Age-related changes in endothelium-dependent hyperpolarization in the rat mesenteric artery. Am J Physiol 265 (2 Pt 2): H509-H516.
    • (1993) Am J Physiol , vol.265 , Issue.2 PART 2
    • Fujii, K.1    Ohmori, S.2    Tominaga, M.3    Abe, I.4    Takata, Y.5    Ohya, Y.6
  • 18
    • 16244364414 scopus 로고    scopus 로고
    • Endothelium-derived hydrogen peroxide accounts for the enhancing effect of an angiotensin-converting enzyme inhibitor on endothelium-derived hyperpolarizing factor-mediated responses in mice
    • Fujiki T, Shimokawa H, Morikawa K, Kubota H, Hatanaka M, Talukder MA, et al. (2005). Endothelium-derived hydrogen peroxide accounts for the enhancing effect of an angiotensin-converting enzyme inhibitor on endothelium-derived hyperpolarizing factor-mediated responses in mice. Arterioscler Thromb Vasc Biol 25: 766-771.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 766-771
    • Fujiki, T.1    Shimokawa, H.2    Morikawa, K.3    Kubota, H.4    Hatanaka, M.5    Talukder, M.A.6
  • 19
    • 0033774380 scopus 로고    scopus 로고
    • Renin-angiotensin system blockade improves endothelial dysfunction in hypertension
    • Goto K, Fujii K, Onaka U, Abe I, Fujishima M, (2000). Renin-angiotensin system blockade improves endothelial dysfunction in hypertension. Hypertension 36: 575-580.
    • (2000) Hypertension , vol.36 , pp. 575-580
    • Goto, K.1    Fujii, K.2    Onaka, U.3    Abe, I.4    Fujishima, M.5
  • 20
    • 84864645795 scopus 로고    scopus 로고
    • Upregulation of endothelium-derived hyperpolarizing factor compensates for the loss of nitric oxide in mesenteric arteries of dahl salt-sensitive hypertensive rats
    • Goto K, Kansui Y, Oniki H, Ohtsubo T, Matsumura K, Kitazono T, (2012). Upregulation of endothelium-derived hyperpolarizing factor compensates for the loss of nitric oxide in mesenteric arteries of dahl salt-sensitive hypertensive rats. Hypertens Res 35: 849-854.
    • (2012) Hypertens Res , vol.35 , pp. 849-854
    • Goto, K.1    Kansui, Y.2    Oniki, H.3    Ohtsubo, T.4    Matsumura, K.5    Kitazono, T.6
  • 21
    • 70349895458 scopus 로고    scopus 로고
    • + channels in normal and impaired EDHF-dilator responses - Relevance to cardiovascular pathologies and drug discovery
    • + channels in normal and impaired EDHF-dilator responses-relevance to cardiovascular pathologies and drug discovery. Br J Pharmacol 157: 509-526.
    • (2009) Br J Pharmacol , vol.157 , pp. 509-526
    • Grgic, I.1    Kaistha, B.P.2    Hoyer, J.3    Kohler, R.4
  • 22
    • 79251633164 scopus 로고    scopus 로고
    • Diet-induced obesity impairs endothelium-derived hyperpolarization via altered potassium channel signaling mechanisms
    • Haddock RE, Grayson TH, Morris MJ, Howitt L, Chadha PS, Sandow SL, (2011). Diet-induced obesity impairs endothelium-derived hyperpolarization via altered potassium channel signaling mechanisms. PLoS ONE 6: e16423.
    • (2011) PLoS ONE , vol.6
    • Haddock, R.E.1    Grayson, T.H.2    Morris, M.J.3    Howitt, L.4    Chadha, P.S.5    Sandow, S.L.6
  • 24
    • 80051669926 scopus 로고    scopus 로고
    • Improvement of endothelium-dependent vasodilations by SKA-31 and SKA-20, activators of small- and intermediate-conductance Ca2+ -activated K+ -channels
    • Hasenau AL, Nielsen G, Morisseau C, Hammock BD, Wulff H, Kohler R, (2011). Improvement of endothelium-dependent vasodilations by SKA-31 and SKA-20, activators of small- and intermediate-conductance Ca2+ -activated K+ -channels. Acta Physiol (Oxf) 203: 117-126.
    • (2011) Acta Physiol (Oxf) , vol.203 , pp. 117-126
    • Hasenau, A.L.1    Nielsen, G.2    Morisseau, C.3    Hammock, B.D.4    Wulff, H.5    Kohler, R.6
  • 25
    • 0034387199 scopus 로고    scopus 로고
    • Endothelium-derived hyperpolarizing factor-fact or fiction?
    • Hecker M, (2000). Endothelium-derived hyperpolarizing factor-fact or fiction? News Physiol Sci 15: 1-5.
    • (2000) News Physiol Sci , vol.15 , pp. 1-5
    • Hecker, M.1
  • 26
    • 34250860659 scopus 로고    scopus 로고
    • Reduced expression of SKCa and IKCa channel proteins in rat small mesenteric arteries during angiotensin II-induced hypertension
    • Hilgers RH, Webb RC, (2007). Reduced expression of SKCa and IKCa channel proteins in rat small mesenteric arteries during angiotensin II-induced hypertension. Am J Physiol Heart Circ Physiol 292: H2275-H2284.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • Hilgers, R.H.1    Webb, R.C.2
  • 27
    • 77949723623 scopus 로고    scopus 로고
    • Twenty-four-hour exposure to altered blood flow modifies endothelial Ca2+-activated K+ channels in rat mesenteric arteries
    • Hilgers RH, Janssen GM, Fazzi GE, De Mey JG, (2010). Twenty-four-hour exposure to altered blood flow modifies endothelial Ca2+-activated K+ channels in rat mesenteric arteries. J Pharmacol Exp Ther 333: 210-217.
    • (2010) J Pharmacol Exp Ther , vol.333 , pp. 210-217
    • Hilgers, R.H.1    Janssen, G.M.2    Fazzi, G.E.3    De Mey, J.G.4
  • 29
    • 77952891052 scopus 로고    scopus 로고
    • Endothelial dysfunction and blood pressure alterations in K+-channel transgenic mice
    • Kohler R, Ruth P, (2010). Endothelial dysfunction and blood pressure alterations in K+-channel transgenic mice. Pflugers Arch 459: 969-976.
    • (2010) Pflugers Arch , vol.459 , pp. 969-976
    • Kohler, R.1    Ruth, P.2
  • 31
    • 84856423507 scopus 로고    scopus 로고
    • Involvement of cyclo-oxygenase-1-mediated prostacyclin synthesis in the vasoconstrictor activity evoked by ACh in mouse arteries
    • Liu B, Luo W, Zhang Y, Li H, Zhu N, Huang D, et al. (2012). Involvement of cyclo-oxygenase-1-mediated prostacyclin synthesis in the vasoconstrictor activity evoked by ACh in mouse arteries. Exp Physiol 97: 277-289.
    • (2012) Exp Physiol , vol.97 , pp. 277-289
    • Liu, B.1    Luo, W.2    Zhang, Y.3    Li, H.4    Zhu, N.5    Huang, D.6
  • 32
    • 77649126524 scopus 로고    scopus 로고
    • Heart disease and stroke statistics - 2010 update: A report from the American Heart Association
    • Lloyd-Jones D, Adams RJ, Brown TM, Carnethon M, Dai S, De Simone G, et al. (2010). Heart disease and stroke statistics-2010 update: a report from the American Heart Association. Circulation 121: e46-e215.
    • (2010) Circulation , vol.121
    • Lloyd-Jones, D.1    Adams, R.J.2    Brown, T.M.3    Carnethon, M.4    Dai, S.5    De Simone, G.6
  • 33
    • 0031939150 scopus 로고    scopus 로고
    • Sex differences in the relative contributions of nitric oxide and EDHF to agonist-stimulated endothelium-dependent relaxations in the rat isolated mesenteric arterial bed
    • McCulloch AI, Randall MD, (1998). Sex differences in the relative contributions of nitric oxide and EDHF to agonist-stimulated endothelium-dependent relaxations in the rat isolated mesenteric arterial bed. Br J Pharmacol 123: 1700-1706.
    • (1998) Br J Pharmacol , vol.123 , pp. 1700-1706
    • McCulloch, A.I.1    Randall, M.D.2
  • 35
    • 0031603012 scopus 로고    scopus 로고
    • Bis-quinolinium cyclophanes: 6,10-diaza-3(1,3),8(1,4)-dibenzena-1,5(1,4)- diquinolinacyclodecaphane (UCL 1684), the first nanomolar, non-peptidic blocker of the apamin-sensitive Ca(2+)-activated K+ channel
    • Rosa JC, Galanakis D, Ganellin CR, Dunn PM, Jenkinson DH, (1998). Bis-quinolinium cyclophanes: 6,10-diaza-3(1,3),8(1,4)-dibenzena-1,5(1,4)- diquinolinacyclodecaphane (UCL 1684), the first nanomolar, non-peptidic blocker of the apamin-sensitive Ca(2+)-activated K+ channel. J Med Chem 41: 2-5.
    • (1998) J Med Chem , vol.41 , pp. 2-5
    • Rosa, J.C.1    Galanakis, D.2    Ganellin, C.R.3    Dunn, P.M.4    Jenkinson, D.H.5
  • 36
    • 2442711422 scopus 로고    scopus 로고
    • Developmental changes in myoendothelial gap junction mediated vasodilator activity in the rat saphenous artery
    • Sandow SL, Goto K, Rummery NM, Hill CE, (2004). Developmental changes in myoendothelial gap junction mediated vasodilator activity in the rat saphenous artery. J Physiol 556 (Pt 3): 875-886.
    • (2004) J Physiol , vol.556 , Issue.PART 3 , pp. 875-886
    • Sandow, S.L.1    Goto, K.2    Rummery, N.M.3    Hill, C.E.4
  • 37
    • 59449098672 scopus 로고    scopus 로고
    • Naphtho[1,2-d]thiazol-2-ylamine (SKA-31), a new activator of KCa2 and KCa3.1 potassium channels, potentiates the endothelium-derived hyperpolarizing factor response and lowers blood pressure
    • Sankaranarayanan A, Raman G, Busch C, Schultz T, Zimin PI, Hoyer J, et al. (2009). Naphtho[1,2-d]thiazol-2-ylamine (SKA-31), a new activator of KCa2 and KCa3.1 potassium channels, potentiates the endothelium-derived hyperpolarizing factor response and lowers blood pressure. Mol Pharmacol 75: 281-295.
    • (2009) Mol Pharmacol , vol.75 , pp. 281-295
    • Sankaranarayanan, A.1    Raman, G.2    Busch, C.3    Schultz, T.4    Zimin, P.I.5    Hoyer, J.6
  • 38
    • 13844303855 scopus 로고    scopus 로고
    • Investigation of vascular responses in endothelial nitric oxide synthase/cyclooxygenase-1 double-knockout mice: Key role for endothelium-derived hyperpolarizing factor in the regulation of blood pressure in vivo
    • Scotland RS, Madhani M, Chauhan S, Moncada S, Andresen J, Nilsson H, et al. (2005). Investigation of vascular responses in endothelial nitric oxide synthase/cyclooxygenase-1 double-knockout mice: key role for endothelium-derived hyperpolarizing factor in the regulation of blood pressure in vivo. Circulation 111: 796-803.
    • (2005) Circulation , vol.111 , pp. 796-803
    • Scotland, R.S.1    Madhani, M.2    Chauhan, S.3    Moncada, S.4    Andresen, J.5    Nilsson, H.6
  • 39
    • 84865232170 scopus 로고    scopus 로고
    • Transient receptor potential canonical type 3 channels facilitate endothelium-derived hyperpolarization-mediated resistance artery vasodilator activity
    • Senadheera S, Kim Y, Grayson TH, Toemoe S, Kochukov MY, Abramowitz J, et al. (2012). Transient receptor potential canonical type 3 channels facilitate endothelium-derived hyperpolarization-mediated resistance artery vasodilator activity. Cardiovasc Res 95: 439-447.
    • (2012) Cardiovasc Res , vol.95 , pp. 439-447
    • Senadheera, S.1    Kim, Y.2    Grayson, T.H.3    Toemoe, S.4    Kochukov, M.Y.5    Abramowitz, J.6
  • 40
    • 33748345798 scopus 로고    scopus 로고
    • Impaired endothelium-derived hyperpolarizing factor-mediated dilations and increased blood pressure in mice deficient of the intermediate-conductance Ca2+-activated K+ channel
    • Si H, Heyken WT, Wolfle SE, Tysiac M, Schubert R, Grgic I, et al. (2006). Impaired endothelium-derived hyperpolarizing factor-mediated dilations and increased blood pressure in mice deficient of the intermediate-conductance Ca2+-activated K+ channel. Circ Res 99: 537-544.
    • (2006) Circ Res , vol.99 , pp. 537-544
    • Si, H.1    Heyken, W.T.2    Wolfle, S.E.3    Tysiac, M.4    Schubert, R.5    Grgic, I.6
  • 41
    • 4644325419 scopus 로고    scopus 로고
    • Activation of human IK and SK Ca2+ -activated K+ channels by NS309 (6,7-dichloro-1H-indole-2,3-dione 3-oxime)
    • Strobaek D, Teuber L, Jorgensen TD, Ahring PK, Kjaer K, Hansen RS, et al. (2004). Activation of human IK and SK Ca2+ -activated K+ channels by NS309 (6,7-dichloro-1H-indole-2,3-dione 3-oxime). Biochim Biophys Acta 1665: 1-5.
    • (2004) Biochim Biophys Acta , vol.1665 , pp. 1-5
    • Strobaek, D.1    Teuber, L.2    Jorgensen, T.D.3    Ahring, P.K.4    Kjaer, K.5    Hansen, R.S.6
  • 42
    • 0033054349 scopus 로고    scopus 로고
    • Endothelium-derived relaxing, contracting and hyperpolarizing factors of mesenteric arteries of hypertensive and normotensive rats
    • Sunano S, Watanabe H, Tanaka S, Sekiguchi F, Shimamura K, (1999). Endothelium-derived relaxing, contracting and hyperpolarizing factors of mesenteric arteries of hypertensive and normotensive rats. Br J Pharmacol 126: 709-716.
    • (1999) Br J Pharmacol , vol.126 , pp. 709-716
    • Sunano, S.1    Watanabe, H.2    Tanaka, S.3    Sekiguchi, F.4    Shimamura, K.5
  • 44
    • 33746192641 scopus 로고    scopus 로고
    • Identification of a cytochrome P450 2C9-derived endothelium-derived hyperpolarizing factor in essential hypertensive patients
    • Taddei S, Versari D, Cipriano A, Ghiadoni L, Galetta F, Franzoni F, et al. (2006). Identification of a cytochrome P450 2C9-derived endothelium-derived hyperpolarizing factor in essential hypertensive patients. J Am Coll Cardiol 48: 508-515.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 508-515
    • Taddei, S.1    Versari, D.2    Cipriano, A.3    Ghiadoni, L.4    Galetta, F.5    Franzoni, F.6
  • 45
  • 46
    • 51049110692 scopus 로고    scopus 로고
    • Crucial role of nitric oxide synthases system in endothelium-dependent hyperpolarization in mice
    • Takaki A, Morikawa K, Tsutsui M, Murayama Y, Tekes E, Yamagishi H, et al. (2008b). Crucial role of nitric oxide synthases system in endothelium-dependent hyperpolarization in mice. J Exp Med 205: 2053-2063.
    • (2008) J Exp Med , vol.205 , pp. 2053-2063
    • Takaki, A.1    Morikawa, K.2    Tsutsui, M.3    Murayama, Y.4    Tekes, E.5    Yamagishi, H.6
  • 47
    • 0043269264 scopus 로고    scopus 로고
    • Altered expression of small-conductance Ca2+-activated K+ (SK3) channels modulates arterial tone and blood pressure
    • Taylor MS, Bonev AD, Gross TP, Eckman DM, Brayden JE, Bond CT, et al. (2003). Altered expression of small-conductance Ca2+-activated K+ (SK3) channels modulates arterial tone and blood pressure. Circ Res 93: 124-131.
    • (2003) Circ Res , vol.93 , pp. 124-131
    • Taylor, M.S.1    Bonev, A.D.2    Gross, T.P.3    Eckman, D.M.4    Brayden, J.E.5    Bond, C.T.6
  • 50
    • 77955293596 scopus 로고    scopus 로고
    • Connexins and gap junctions in the EDHF phenomenon and conducted vasomotor responses
    • de Wit C, Griffith TM, (2010). Connexins and gap junctions in the EDHF phenomenon and conducted vasomotor responses. Pflugers Arch 459: 897-914.
    • (2010) Pflugers Arch , vol.459 , pp. 897-914
    • De Wit, C.1    Griffith, T.M.2
  • 51
    • 0034608869 scopus 로고    scopus 로고
    • Design of a potent and selective inhibitor of the intermediate- conductance Ca2+-activated K+ channel, IKCa1: A potential immunosuppressant
    • Wulff H, Miller MJ, Hansel W, Grissmer S, Cahalan MD, Chandy KG, (2000). Design of a potent and selective inhibitor of the intermediate-conductance Ca2+-activated K+ channel, IKCa1: a potential immunosuppressant. Proc Natl Acad Sci U S A 97: 8151-8156.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 8151-8156
    • Wulff, H.1    Miller, M.J.2    Hansel, W.3    Grissmer, S.4    Cahalan, M.D.5    Chandy, K.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.