메뉴 건너뛰기




Volumn 8, Issue 6, 2009, Pages 902-908

Upregulation of Nox4 in the aging vasculature and its association with smooth muscle cell polyploidy

Author keywords

Aging; Hypertrophy; NADPH oxidase 4 (Nox4); Polyploidy; Vascular smooth muscle

Indexed keywords

REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SURVIVIN;

EID: 65349104490     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.8.6.7900     Document Type: Article
Times cited : (57)

References (62)
  • 1
    • 1242272076 scopus 로고    scopus 로고
    • Vascular smooth muscle polyploidization as a biomarker for aging and its impact on differential gene expression
    • Jones MR, Ravid K. Vascular smooth muscle polyploidization as a biomarker for aging and its impact on differential gene expression. J Biol Chem 2004; 279:5306-13.
    • (2004) J Biol Chem , vol.279 , pp. 5306-5313
    • Jones, M.R.1    Ravid, K.2
  • 2
    • 33947427515 scopus 로고    scopus 로고
    • Increased polyploidy in aortic vascular smooth muscle cells during aging is marked by cellular senescence
    • Yang D, McCrann DJ, Nguyen H, St. Hilaire C, DePinho RA, Jones MR, et al. Increased polyploidy in aortic vascular smooth muscle cells during aging is marked by cellular senescence. Aging Cell 2007; 6:257-60.
    • (2007) Aging Cell , vol.6 , pp. 257-260
    • Yang, D.1    McCrann, D.J.2    Nguyen, H.3    St. Hilaire, C.4    DePinho, R.A.5    Jones, M.R.6
  • 3
    • 21344440000 scopus 로고    scopus 로고
    • Reactive oxygen species as mediators of cellular senescence
    • Colavitti R, Finkel T. Reactive oxygen species as mediators of cellular senescence. IUBMB Life 2005; 57:277-81.
    • (2005) IUBMB Life , vol.57 , pp. 277-281
    • Colavitti, R.1    Finkel, T.2
  • 4
    • 0034626735 scopus 로고    scopus 로고
    • Oxidants, oxidative stress and the biology of ageing
    • Finkel T, Holbrook NJ. Oxidants, oxidative stress and the biology of ageing. Nature 2000; 408:239-47.
    • (2000) Nature , vol.408 , pp. 239-247
    • Finkel, T.1    Holbrook, N.J.2
  • 5
    • 0034678050 scopus 로고    scopus 로고
    • Homocysteine accelerates endothelial cell senescence
    • Xu D, Neville R, Finkel T. Homocysteine accelerates endothelial cell senescence. FEBS Lett 2000; 470:20-4.
    • (2000) FEBS Lett , vol.470 , pp. 20-24
    • Xu, D.1    Neville, R.2    Finkel, T.3
  • 6
    • 4644310560 scopus 로고    scopus 로고
    • Role of oxidative modifications in atherosclerosis
    • Stocker R, Keaney JF Jr. Role of oxidative modifications in atherosclerosis. Physiol Rev 2004; 84:1381-478.
    • (2004) Physiol Rev , vol.84 , pp. 1381-1478
    • Stocker, R.1    Keaney Jr, J.F.2
  • 7
    • 15744390035 scopus 로고    scopus 로고
    • Neuronal expression of the NADPH oxidase NOX4, and its regulation in mouse experimental brain ischemia
    • Vallet P, Charnay Y, Steger K, Ogier-Denis E, Kovari E, Herrmann F, et al. Neuronal expression of the NADPH oxidase NOX4, and its regulation in mouse experimental brain ischemia. Neuroscience 2005; 132:233-8.
    • (2005) Neuroscience , vol.132 , pp. 233-238
    • Vallet, P.1    Charnay, Y.2    Steger, K.3    Ogier-Denis, E.4    Kovari, E.5    Herrmann, F.6
  • 8
    • 0028365310 scopus 로고
    • Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells
    • Griendling KK, Minieri CA, Ollerenshaw JD, Alexander RW. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res 1994; 74:1141-8.
    • (1994) Circ Res , vol.74 , pp. 1141-1148
    • Griendling, K.K.1    Minieri, C.A.2    Ollerenshaw, J.D.3    Alexander, R.W.4
  • 9
    • 0032737361 scopus 로고    scopus 로고
    • Ang II-stimulated superoxide production is mediated via phospholipase D in human vascular smooth muscle cells
    • Touyz RM, Schiffrin EL. Ang II-stimulated superoxide production is mediated via phospholipase D in human vascular smooth muscle cells. Hypertension 1999; 34:976-82.
    • (1999) Hypertension , vol.34 , pp. 976-982
    • Touyz, R.M.1    Schiffrin, E.L.2
  • 10
    • 22144435873 scopus 로고    scopus 로고
    • Intracellular mechanisms involved in vascular remodelling of resistance arteries in hypertension: Role of angiotensin II
    • Touyz RM. Intracellular mechanisms involved in vascular remodelling of resistance arteries in hypertension: role of angiotensin II. Exp Physiol 2005; 90:449-55.
    • (2005) Exp Physiol , vol.90 , pp. 449-455
    • Touyz, R.M.1
  • 11
    • 33750880616 scopus 로고    scopus 로고
    • Vascular smooth muscle cell polyploidy and cardiomyocyte hypertrophy due to chronic NOS inhibition in vivo
    • Devlin A, Brosnan M, Graham D, Morton J, McPhaden A, McIntyre M, et al. Vascular smooth muscle cell polyploidy and cardiomyocyte hypertrophy due to chronic NOS inhibition in vivo. Am J Physiol 1998; 274:52-9.
    • (1998) Am J Physiol , vol.274 , pp. 52-59
    • Devlin, A.1    Brosnan, M.2    Graham, D.3    Morton, J.4    McPhaden, A.5    McIntyre, M.6
  • 12
    • 0034851729 scopus 로고    scopus 로고
    • Polyploidy associated with oxidative injury attenuates proliferative potential of cells
    • Gorla GR, Malhi H, Gupta S. Polyploidy associated with oxidative injury attenuates proliferative potential of cells. J Cell Sci 2001; 114:2943-51.
    • (2001) J Cell Sci , vol.114 , pp. 2943-2951
    • Gorla, G.R.1    Malhi, H.2    Gupta, S.3
  • 13
    • 0034604540 scopus 로고    scopus 로고
    • Selective activation of p38 MAPK cascade and mitotic arrest caused by low level oxidative stress
    • Kurata S. Selective activation of p38 MAPK cascade and mitotic arrest caused by low level oxidative stress. J Biol Chem 2000; 275:23413-6.
    • (2000) J Biol Chem , vol.275 , pp. 23413-23416
    • Kurata, S.1
  • 15
    • 0037040947 scopus 로고    scopus 로고
    • Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling
    • Mollnau H, Wendt M, Szocs K, Lassegue B, Schulz E, Oelze M, et al. Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling. Circ Res 2002; 90:58-65.
    • (2002) Circ Res , vol.90 , pp. 58-65
    • Mollnau, H.1    Wendt, M.2    Szocs, K.3    Lassegue, B.4    Schulz, E.5    Oelze, M.6
  • 16
    • 0036936265 scopus 로고    scopus 로고
    • NAD(P)H oxidase-derived reactive oxygen species as mediators of angiotensin II signaling
    • Hanna IR, Taniyama Y, Szocs K, Rocic P, Griendling KK. NAD(P)H oxidase-derived reactive oxygen species as mediators of angiotensin II signaling. Antioxid Redox Signal 2002; 4:899-914.
    • (2002) Antioxid Redox Signal , vol.4 , pp. 899-914
    • Hanna, I.R.1    Taniyama, Y.2    Szocs, K.3    Rocic, P.4    Griendling, K.K.5
  • 17
    • 0345690184 scopus 로고    scopus 로고
    • Role of NADPH oxidases in the control of vascular gene expression
    • Brandes RP. Role of NADPH oxidases in the control of vascular gene expression. Antioxid Redox Signal 2003; 5:803-11.
    • (2003) Antioxid Redox Signal , vol.5 , pp. 803-811
    • Brandes, R.P.1
  • 18
    • 0035584538 scopus 로고    scopus 로고
    • Upregulation of the vascular NAD(P)H-oxidase isoforms Nox1 and Nox4 by the renin-angiotensin system in vitro and in vivo
    • Wingler K, Wunsch S, Kreutz R, Rothermund L, Paul M, Schmidt HH. Upregulation of the vascular NAD(P)H-oxidase isoforms Nox1 and Nox4 by the renin-angiotensin system in vitro and in vivo. Free Radic Biol Med 2001; 31:1456-64.
    • (2001) Free Radic Biol Med , vol.31 , pp. 1456-1464
    • Wingler, K.1    Wunsch, S.2    Kreutz, R.3    Rothermund, L.4    Paul, M.5    Schmidt, H.H.6
  • 19
    • 0035844030 scopus 로고    scopus 로고
    • Novel gp91(phox) homologues in vascular smooth muscle cells: Nox1 mediates angiotensin II-induced superoxide formation and redox-sensitive signaling pathways
    • Lassegue B, Sorescu D, Szocs K, Yin Q, Akers M, Zhang Y, et al. Novel gp91(phox) homologues in vascular smooth muscle cells: nox1 mediates angiotensin II-induced superoxide formation and redox-sensitive signaling pathways. Circ Res 2001; 88:888-94.
    • (2001) Circ Res , vol.88 , pp. 888-894
    • Lassegue, B.1    Sorescu, D.2    Szocs, K.3    Yin, Q.4    Akers, M.5    Zhang, Y.6
  • 20
    • 27444447834 scopus 로고    scopus 로고
    • Nox1 over- expression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice
    • Dikalova A, Clempus R, Lassegue B, Cheng G, McCoy J, Dikalov S, et al. Nox1 over- expression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice. Circulation 2005; 112:2668-76.
    • (2005) Circulation , vol.112 , pp. 2668-2676
    • Dikalova, A.1    Clempus, R.2    Lassegue, B.3    Cheng, G.4    McCoy, J.5    Dikalov, S.6
  • 23
    • 0037076798 scopus 로고    scopus 로고
    • Expression of a functionally active gp91phox-containing neutrophil-type NAD(P)H oxidase in smooth muscle cells from human resistance arteries: Regulation by angiotensin II
    • Touyz RM, Chen X, Tabet F, Yao G, He G, Quinn MT, et al. Expression of a functionally active gp91phox-containing neutrophil-type NAD(P)H oxidase in smooth muscle cells from human resistance arteries: regulation by angiotensin II. Circ Res 2002; 90:1205-13.
    • (2002) Circ Res , vol.90 , pp. 1205-1213
    • Touyz, R.M.1    Chen, X.2    Tabet, F.3    Yao, G.4    He, G.5    Quinn, M.T.6
  • 24
    • 20144389459 scopus 로고    scopus 로고
    • Vascular smooth muscle cell polyploidization involves changes in chromosome passenger proteins and an endomitotic cell cycle
    • Nagata Y, Jones MR, Nguyen HG, McCrann DJ, St. Hilaire C, Schreiber BM, et al. Vascular smooth muscle cell polyploidization involves changes in chromosome passenger proteins and an endomitotic cell cycle. Exp Cell Res 2005; 305:277-91.
    • (2005) Exp Cell Res , vol.305 , pp. 277-291
    • Nagata, Y.1    Jones, M.R.2    Nguyen, H.G.3    McCrann, D.J.4    St. Hilaire, C.5    Schreiber, B.M.6
  • 25
    • 0033791526 scopus 로고    scopus 로고
    • Akt1/PKB upregulation leads to vascular smooth muscle cell hypertrophy and polyploidization
    • Hixon ML, Muro-Cacho C, Wagner MW, Obejero-Paz C, Millie E, Fujio Y, et al. Akt1/PKB upregulation leads to vascular smooth muscle cell hypertrophy and polyploidization. J Clin Invest 2000; 106:1011-20.
    • (2000) J Clin Invest , vol.106 , pp. 1011-1020
    • Hixon, M.L.1    Muro-Cacho, C.2    Wagner, M.W.3    Obejero-Paz, C.4    Millie, E.5    Fujio, Y.6
  • 27
    • 33947327842 scopus 로고    scopus 로고
    • Oxidative stress overrides the spindle checkpoint
    • D'Angiolella V, Santarpia C, Grieco D. Oxidative stress overrides the spindle checkpoint. Cell Cycle 2007; 6:576-9.
    • (2007) Cell Cycle , vol.6 , pp. 576-579
    • D'Angiolella, V.1    Santarpia, C.2    Grieco, D.3
  • 28
    • 33847185842 scopus 로고    scopus 로고
    • A redox cycle within the cell cycle: Ring in the old with the new
    • Menon SG, Goswami PC. A redox cycle within the cell cycle: Ring in the old with the new Oncogene 2007; 26:1101-9.
    • (2007) Oncogene , vol.26 , pp. 1101-1109
    • Menon, S.G.1    Goswami, P.C.2
  • 30
    • 33749830382 scopus 로고    scopus 로고
    • Oxidative stress induces a prolonged but reversible arrest in p53-null cancer cells, involving a Chk1-dependent G2 checkpoint
    • Macip S, Kosoy A, Lee SW, O'Connell MJ, Aaronson SA. Oxidative stress induces a prolonged but reversible arrest in p53-null cancer cells, involving a Chk1-dependent G2 checkpoint. Oncogene 2006; 25:6037-47.
    • (2006) Oncogene , vol.25 , pp. 6037-6047
    • Macip, S.1    Kosoy, A.2    Lee, S.W.3    O'Connell, M.J.4    Aaronson, S.A.5
  • 32
    • 50549087736 scopus 로고    scopus 로고
    • Growth stimulation leads to cellular senescence when the cell cycle is blocked
    • Demidenko ZN, Blagosklonny MV. Growth stimulation leads to cellular senescence when the cell cycle is blocked. Cell Cycle 2008; 7:3355-61.
    • (2008) Cell Cycle , vol.7 , pp. 3355-3361
    • Demidenko, Z.N.1    Blagosklonny, M.V.2
  • 33
    • 34447525369 scopus 로고    scopus 로고
    • Nox4 mediates TGFbeta1-induced retinoblastoma protein phosphorylation, proliferation and hypertrophy in human airway smooth muscle cells
    • Sturrock A, Huecksteadt TP, Norman K, Sanders K, Murphy TM, Chitano P, et al. Nox4 mediates TGFbeta1-induced retinoblastoma protein phosphorylation, proliferation and hypertrophy in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2007; 292:1543-55.
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.292 , pp. 1543-1555
    • Sturrock, A.1    Huecksteadt, T.P.2    Norman, K.3    Sanders, K.4    Murphy, T.M.5    Chitano, P.6
  • 34
    • 33846597164 scopus 로고    scopus 로고
    • Resveratrol modulates mRNA transcripts of genes related to redox metabolism and cell proliferation in non-small-cell lung carcinoma cells
    • Hu Y, Rahlfs S, Mersch-Sundermann V, Becker K. Resveratrol modulates mRNA transcripts of genes related to redox metabolism and cell proliferation in non-small-cell lung carcinoma cells. Biol Chem 2007; 388:207-19.
    • (2007) Biol Chem , vol.388 , pp. 207-219
    • Hu, Y.1    Rahlfs, S.2    Mersch-Sundermann, V.3    Becker, K.4
  • 35
    • 33845726964 scopus 로고    scopus 로고
    • Increased ROS generation and p53 activation in alpha-lipoic acid-induced apoptosis of hepatoma cells
    • Simbula G, Columbano A, Ledda-Columbano GM, Sanna L, Deidda M, Diana A, et al. Increased ROS generation and p53 activation in alpha-lipoic acid-induced apoptosis of hepatoma cells. Apoptosis 2007; 12:113-23.
    • (2007) Apoptosis , vol.12 , pp. 113-123
    • Simbula, G.1    Columbano, A.2    Ledda-Columbano, G.M.3    Sanna, L.4    Deidda, M.5    Diana, A.6
  • 36
    • 33845760859 scopus 로고    scopus 로고
    • Sulindac-derived reactive oxygen species induce apoptosis of human multiple myeloma cells via p38 mitogen activated protein kinase-induced mitochondrial dysfunction
    • Seo SK, Lee HC, Woo SH, Jin HO, Yoo DH, Lee SJ, et al. Sulindac-derived reactive oxygen species induce apoptosis of human multiple myeloma cells via p38 mitogen activated protein kinase-induced mitochondrial dysfunction. Apoptosis 2007; 12:195-209.
    • (2007) Apoptosis , vol.12 , pp. 195-209
    • Seo, S.K.1    Lee, H.C.2    Woo, S.H.3    Jin, H.O.4    Yoo, D.H.5    Lee, S.J.6
  • 37
    • 33747625689 scopus 로고    scopus 로고
    • Vascular smooth muscle cells undergo telomere-based senescence in human atherosclerosis: Effects of telom- erase and oxidative stress
    • Matthews C, Gorenne I, Scott S, Figg N, Kirkpatrick P, Ritchie A, et al. Vascular smooth muscle cells undergo telomere-based senescence in human atherosclerosis: effects of telom- erase and oxidative stress. Circ Res 2006; 99:156-64.
    • (2006) Circ Res , vol.99 , pp. 156-164
    • Matthews, C.1    Gorenne, I.2    Scott, S.3    Figg, N.4    Kirkpatrick, P.5    Ritchie, A.6
  • 39
    • 36249022195 scopus 로고    scopus 로고
    • Vascular superoxide and hydrogen peroxide production and oxidative stress resistance in two closely related rodent species with disparate longevity
    • Csiszar A, Labinskyy N, Zhao X, Hu F, Serpillon S, Huang Z, et al. Vascular superoxide and hydrogen peroxide production and oxidative stress resistance in two closely related rodent species with disparate longevity. Aging Cell 2007; 6:783-97.
    • (2007) Aging Cell , vol.6 , pp. 783-797
    • Csiszar, A.1    Labinskyy, N.2    Zhao, X.3    Hu, F.4    Serpillon, S.5    Huang, Z.6
  • 40
    • 33750499504 scopus 로고    scopus 로고
    • Cell senescence: Hypertrophic arrest beyond the restriction point
    • Blagosklonny MV. Cell senescence: Hypertrophic arrest beyond the restriction point. J Cell Physiol 2006; 209:592-7.
    • (2006) J Cell Physiol , vol.209 , pp. 592-597
    • Blagosklonny, M.V.1
  • 41
    • 38149107357 scopus 로고    scopus 로고
    • Paradoxes of aging
    • Blagosklonny MV. Paradoxes of aging. Cell Cycle 2007; 6:2997-3003.
    • (2007) Cell Cycle , vol.6 , pp. 2997-3003
    • Blagosklonny, M.V.1
  • 42
    • 55849152355 scopus 로고    scopus 로고
    • Aging: ROS or TOR
    • Blagosklonny MV. Aging: ROS or TOR. Cell Cycle 2008; 7:3344-54.
    • (2008) Cell Cycle , vol.7 , pp. 3344-3354
    • Blagosklonny, M.V.1
  • 44
    • 33644769115 scopus 로고    scopus 로고
    • Mammalian target of rapamycin (mTOR) regulates both proliferation of megakaryocyte progenitors and late stages of megakaryocyte differentiation
    • Raslova H, Baccini V, Loussaief L, Comba B, Larghero J, Debili N, et al. Mammalian target of rapamycin (mTOR) regulates both proliferation of megakaryocyte progenitors and late stages of megakaryocyte differentiation. Blood 2006; 107:2303-10.
    • (2006) Blood , vol.107 , pp. 2303-2310
    • Raslova, H.1    Baccini, V.2    Loussaief, L.3    Comba, B.4    Larghero, J.5    Debili, N.6
  • 49
    • 33748351173 scopus 로고    scopus 로고
    • Angiotensin II induces premature senescence of vascular smooth muscle cells and accelerates the development of atherosclerosis via a p21-dependent pathway
    • Kunieda T, Minamino T, Nishi J, Tateno K, Oyama T, Katsuno T, et al. Angiotensin II induces premature senescence of vascular smooth muscle cells and accelerates the development of atherosclerosis via a p21-dependent pathway. Circulation 2006; 114:953-60.
    • (2006) Circulation , vol.114 , pp. 953-960
    • Kunieda, T.1    Minamino, T.2    Nishi, J.3    Tateno, K.4    Oyama, T.5    Katsuno, T.6
  • 50
    • 2342527764 scopus 로고    scopus 로고
    • Aberrant quantity and localization of Aurora-B/AIM-1 and survivin during megakaryocyte polyploidization and the consequences of Aurora-B/AIM-1-deregulated expression
    • Zhang Y, Nagata Y, Yu G, Nguyen HG, Jones MR, Toselli P, et al. Aberrant quantity and localization of Aurora-B/AIM-1 and survivin during megakaryocyte polyploidization and the consequences of Aurora-B/AIM-1-deregulated expression. Blood 2004; 103:3717-26.
    • (2004) Blood , vol.103 , pp. 3717-3726
    • Zhang, Y.1    Nagata, Y.2    Yu, G.3    Nguyen, H.G.4    Jones, M.R.5    Toselli, P.6
  • 52
    • 0345826036 scopus 로고    scopus 로고
    • tosis. J Biol Chem 2004; 279:2077-84.
    • tosis. J Biol Chem 2004; 279:2077-84.
  • 53
    • 9144247196 scopus 로고    scopus 로고
    • Downregulation of survivin by antisense oligonucleotides increases apoptosis, inhibits cytokinesis and anchorage-independent growth
    • Chen J, Wu W, Tahir SK, Kroeger PE, Rosenberg SH, Cowsert LM, et al. Downregulation of survivin by antisense oligonucleotides increases apoptosis, inhibits cytokinesis and anchorage-independent growth. Neoplasia 2000; 2:235-41.
    • (2000) Neoplasia , vol.2 , pp. 235-241
    • Chen, J.1    Wu, W.2    Tahir, S.K.3    Kroeger, P.E.4    Rosenberg, S.H.5    Cowsert, L.M.6
  • 54
    • 0033258543 scopus 로고    scopus 로고
    • Pleiotropic cell- division defects and apoptosis induced by interference with survivin function
    • Li F, Ackermann EJ, Bennett CF, Rothermel AL, Plescia J, Tognin S, et al. Pleiotropic cell- division defects and apoptosis induced by interference with survivin function. Nat Cell Biol 1999; 1:461-6.
    • (1999) Nat Cell Biol , vol.1 , pp. 461-466
    • Li, F.1    Ackermann, E.J.2    Bennett, C.F.3    Rothermel, A.L.4    Plescia, J.5    Tognin, S.6
  • 55
    • 33750003233 scopus 로고    scopus 로고
    • Synergistic induction of apoptosis by sulindac and arsenic trioxide in human lung cancer A549 cells via reactive oxygen species-dependent downregulation of survivin
    • Jin HO, Yoon SI, Seo SK, Lee HC, Woo SH, Yoo DH, et al. Synergistic induction of apoptosis by sulindac and arsenic trioxide in human lung cancer A549 cells via reactive oxygen species-dependent downregulation of survivin. Biochem Pharmacol 2006; 72:1228-36.
    • (2006) Biochem Pharmacol , vol.72 , pp. 1228-1236
    • Jin, H.O.1    Yoon, S.I.2    Seo, S.K.3    Lee, H.C.4    Woo, S.H.5    Yoo, D.H.6
  • 56
    • 34047264640 scopus 로고    scopus 로고
    • Molecular mechanisms of transactivation and doxorubicin-mediated repression of survivin gene in cancer cells
    • Esteve PO, Chin HG, Pradhan S. Molecular mechanisms of transactivation and doxorubicin-mediated repression of survivin gene in cancer cells. J Biol Chem 2007; 282:2615-25.
    • (2007) J Biol Chem , vol.282 , pp. 2615-2625
    • Esteve, P.O.1    Chin, H.G.2    Pradhan, S.3
  • 57
    • 1642576201 scopus 로고    scopus 로고
    • Sensitization for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by the chemopreventive agent resveratrol
    • Fulda S, Debatin KM. Sensitization for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by the chemopreventive agent resveratrol. Cancer Res 2004; 64:337-46.
    • (2004) Cancer Res , vol.64 , pp. 337-346
    • Fulda, S.1    Debatin, K.M.2
  • 59
    • 42749091176 scopus 로고    scopus 로고
    • Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway
    • Vitale I, Galluzzi L, Vivet S, Nanty L, Dessen P, Senovilla L, et al. Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway. PLoS ONE 2007; 2:1337.
    • (2007) PLoS ONE , vol.2 , pp. 1337
    • Vitale, I.1    Galluzzi, L.2    Vivet, S.3    Nanty, L.4    Dessen, P.5    Senovilla, L.6
  • 60
    • 45849116227 scopus 로고    scopus 로고
    • Genetic stability of senescence reverted cells: Genome reduction division of polyploidy cells, aneuploidy and neoplasia
    • Walen KH. Genetic stability of senescence reverted cells: Genome reduction division of polyploidy cells, aneuploidy and neoplasia. Cell Cycle 2008; 7:1623-9.
    • (2008) Cell Cycle , vol.7 , pp. 1623-1629
    • Walen, K.H.1
  • 61
    • 0023277545 scopus 로고
    • Single step method of RNA isolation by acid Guanidinium Thiocyanate-Phenol-Chloroform extraction
    • Chomczynski P, Sacchi N. Single step method of RNA isolation by acid Guanidinium Thiocyanate-Phenol-Chloroform extraction. Anal Biochem 1987; 162:156.
    • (1987) Anal Biochem , vol.162 , pp. 156
    • Chomczynski, P.1    Sacchi, N.2
  • 62
    • 0031951593 scopus 로고    scopus 로고
    • An A3-subtype adenosine receptor is highly expressed in rat vascular smooth muscle cells: Its role in attenuating adenosine-induced increase in cAMP
    • Zhao Z, Francis C, Ravid K. An A3-subtype adenosine receptor is highly expressed in rat vascular smooth muscle cells: its role in attenuating adenosine-induced increase in cAMP. Microvasc Res 1997; 54:243-52.
    • (1997) Microvasc Res , vol.54 , pp. 243-252
    • Zhao, Z.1    Francis, C.2    Ravid, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.