메뉴 건너뛰기




Volumn 19, Issue 12, 1999, Pages 2854-2862

Augmented expression of inducible NO synthase in vascular smooth muscle cells during aging is associated with enhanced NF-κB activation

Author keywords

Age; Inducible nitric oxide synthase; Nitric oxide; Nuclear factor B; Vascular smooth muscle cells

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MESSENGER RNA; NITRIC OXIDE SYNTHASE;

EID: 0033392430     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.19.12.2854     Document Type: Article
Times cited : (62)

References (46)
  • 1
    • 0028863627 scopus 로고
    • Molecular mechanisms and therapeutic strategies related to nitric oxide
    • Moncada S, Higgs EA. Molecular mechanisms and therapeutic strategies related to nitric oxide. FASEB J. 1995;9:1319-1330.
    • (1995) FASEB J. , vol.9 , pp. 1319-1330
    • Moncada, S.1    Higgs, E.A.2
  • 2
    • 0026655617 scopus 로고
    • Interferon-γ and tumor necrosis factor synergize to induce nitric oxide production and inhibit mitochondrial respiration in vascular smooth muscle cells
    • Geng Y, Hansson GK, Holme E. Interferon-γ and tumor necrosis factor synergize to induce nitric oxide production and inhibit mitochondrial respiration in vascular smooth muscle cells. Circ Res. 1992;71: 1268-1276.
    • (1992) Circ Res. , vol.71 , pp. 1268-1276
    • Geng, Y.1    Hansson, G.K.2    Holme, E.3
  • 3
    • 0029887353 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase inhibits platelet adhesion and restores blood flow in the injured artery
    • Yan ZQ, Yokota T, Zhang WG, Hansson GK. Expression of inducible nitric oxide synthase inhibits platelet adhesion and restores blood flow in the injured artery. Circ Res. 1996;79:38-44.
    • (1996) Circ Res. , vol.79 , pp. 38-44
    • Yan, Z.Q.1    Yokota, T.2    Zhang, W.G.3    Hansson, G.K.4
  • 4
    • 0031906154 scopus 로고    scopus 로고
    • Overexpression of inducible nitric oxide synthase by neointimal smooth muscle cells
    • Yan ZQ, Hansson GK. Overexpression of inducible nitric oxide synthase by neointimal smooth muscle cells. Circ Res. 1998;82:21-29.
    • (1998) Circ Res. , vol.82 , pp. 21-29
    • Yan, Z.Q.1    Hansson, G.K.2
  • 5
    • 0028850008 scopus 로고
    • The cytokine responsive vascular smooth muscle cell enhancer of inducible nitric oxide synthase: Activation by nuclear factor-κB
    • Spink J, Cohen J, Evans TJ. The cytokine responsive vascular smooth muscle cell enhancer of inducible nitric oxide synthase: activation by nuclear factor-κB. J Biol Chem. 1995;270:29541-29547.
    • (1995) J Biol Chem. , vol.270 , pp. 29541-29547
    • Spink, J.1    Cohen, J.2    Evans, T.J.3
  • 7
    • 0027939931 scopus 로고
    • Role of transcription factor NE-κB/Rel in induction of nitric oxide synthase
    • Xie QW, Kashiwabara Y, Nathan C. Role of transcription factor NE-κB/Rel in induction of nitric oxide synthase. J Biol Chem. 1994;269: 4705-4708.
    • (1994) J Biol Chem. , vol.269 , pp. 4705-4708
    • Xie, Q.W.1    Kashiwabara, Y.2    Nathan, C.3
  • 9
    • 0025078530 scopus 로고
    • Cloning of the p50 DNA binding subunit of NF-κB: Homology to rel and dorsal
    • Ghosh S, Gifford AM, Riviere LR, Tempst P, Nolan GP, Baltimore D. Cloning of the p50 DNA binding subunit of NF-κB: homology to rel and dorsal. Cell. 1990;62:1019-1029.
    • (1990) Cell , vol.62 , pp. 1019-1029
    • Ghosh, S.1    Gifford, A.M.2    Riviere, L.R.3    Tempst, P.4    Nolan, G.P.5    Baltimore, D.6
  • 10
    • 0023724778 scopus 로고
    • IκB: A specific inhibitor of the NF-κB transcription factor
    • Baeuerle PA, Baltimore D. IκB: a specific inhibitor of the NF-κB transcription factor. Science. 1988;242:540-546.
    • (1988) Science , vol.242 , pp. 540-546
    • Baeuerle, P.A.1    Baltimore, D.2
  • 11
    • 0027332498 scopus 로고
    • The IκB proteins: Multifunctional regulators of Rel/NF-κB transcription factors
    • Beg AA, Baldwin AJ. The IκB proteins: multifunctional regulators of Rel/NF-κB transcription factors. Genes Dev. 1993;7:2064-2070.
    • (1993) Genes Dev. , vol.7 , pp. 2064-2070
    • Beg, A.A.1    Baldwin, A.J.2
  • 13
    • 0025943986 scopus 로고
    • The p65 subunit is responsible for the strong transcription activating potential of NF-κB
    • Schmitz ML, Baeuerle PA. The p65 subunit is responsible for the strong transcription activating potential of NF-κB. EMBO J. 1991;10: 3805-3817.
    • (1991) EMBO J. , vol.10 , pp. 3805-3817
    • Schmitz, M.L.1    Baeuerle, P.A.2
  • 14
    • 0027176524 scopus 로고
    • Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB
    • Henkel T, Machleidt T, Alkalay I, Kronke M, Ben NY, Baeuerle PA. Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB. Nature. 1993;365:182-185.
    • (1993) Nature , vol.365 , pp. 182-185
    • Henkel, T.1    Machleidt, T.2    Alkalay, I.3    Kronke, M.4    Ben, N.Y.5    Baeuerle, P.A.6
  • 15
    • 0029874138 scopus 로고    scopus 로고
    • The NF-κB and IκB proteins: New discoveries and insights
    • Baldwin AJ. The NF-κB and IκB proteins: new discoveries and insights. Annu Rev Immunol. 1996;14:649-683.
    • (1996) Annu Rev Immunol. , vol.14 , pp. 649-683
    • Baldwin, A.J.1
  • 16
    • 0030615201 scopus 로고    scopus 로고
    • Mechanisms of disease: Nuclear factor-κB: A pivotal transcription factor in chronic inflammatory diseases
    • Barnes PJ, Larin M. Mechanisms of disease: nuclear factor-κB: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med. 1997;336:1066-1071.
    • (1997) N Engl J Med. , vol.336 , pp. 1066-1071
    • Barnes, P.J.1    Larin, M.2
  • 17
    • 0343183539 scopus 로고
    • Production of platelet-derived growth factor-like molecules by cultured arterial smooth muscle cells accompanies proliferation after arterial injury
    • Walker LN, Bowen PD, Ross R, Reidy MA. Production of platelet-derived growth factor-like molecules by cultured arterial smooth muscle cells accompanies proliferation after arterial injury. Proc Natl Acad Sci U S A. 1986;83:7311-7315.
    • (1986) Proc Natl Acad Sci U S A , vol.83 , pp. 7311-7315
    • Walker, L.N.1    Bowen, P.D.2    Ross, R.3    Reidy, M.A.4
  • 18
    • 0028179532 scopus 로고
    • Rat aortic smooth muscle cells isolated from different layers and at different times after endothelial denudation show distinct biological features in vitro
    • Orlandi A, Ehrlich HP, Ropraz P, Spagnoli LG, Gabbiani G. Rat aortic smooth muscle cells isolated from different layers and at different times after endothelial denudation show distinct biological features in vitro. Arterioscler Thromb. 1994;14:982-989.
    • (1994) Arterioscler Thromb. , vol.14 , pp. 982-989
    • Orlandi, A.1    Ehrlich, H.P.2    Ropraz, P.3    Spagnoli, L.G.4    Gabbiani, G.5
  • 19
    • 0028132601 scopus 로고
    • Isolation of a morphologically and functionally distinct smooth muscle cell type from the intimal aspect of the normal rat aorta: Evidence for smooth muscle cell heterogeneity
    • Villaschi S, Nicosia RF, Smith MR. Isolation of a morphologically and functionally distinct smooth muscle cell type from the intimal aspect of the normal rat aorta: evidence for smooth muscle cell heterogeneity. In Vitro Cell Dev Biol Anim. 1994;30A:589-595.
    • (1994) In Vitro Cell Dev Biol Anim. , vol.30 A , pp. 589-595
    • Villaschi, S.1    Nicosia, R.F.2    Smith, M.R.3
  • 20
    • 0027363216 scopus 로고
    • Age influences the replicative activity and the differentiation features of cultured rat aortic smooth muscle cell populations and clones
    • Bochaton-Piallat M, Gabbiani F, Ropraz P, Gabbiani G. Age influences the replicative activity and the differentiation features of cultured rat aortic smooth muscle cell populations and clones. Arterioscler Thromb. 1993;13:1449-1455.
    • (1993) Arterioscler Thromb. , vol.13 , pp. 1449-1455
    • Bochaton-Piallat, M.1    Gabbiani, F.2    Ropraz, P.3    Gabbiani, G.4
  • 21
    • 0029952051 scopus 로고    scopus 로고
    • Phenotypic heterogeneity of rat arterial smooth muscle cell clones: Implications for the development of experimental intimai thickening
    • Bochaton-Piallat M, Ropraz P, Gabbiani F, Gabbiani G. Phenotypic heterogeneity of rat arterial smooth muscle cell clones: implications for the development of experimental intimai thickening. Arterioscler Thromb Vasc Biol. 1996;16:815-820.
    • (1996) Arterioscler Thromb Vasc Biol. , vol.16 , pp. 815-820
    • Bochaton-Piallat, M.1    Ropraz, P.2    Gabbiani, F.3    Gabbiani, G.4
  • 23
    • 0031019611 scopus 로고    scopus 로고
    • Cellular retinol-binding protein-1 is expressed by distinct subsets of rat arterial smooth muscle cells in vitro and in vivo
    • Neuville P, Geinoz A, Benzonana G, Redard M, Gabbiani F, Ropraz P, Gabbiani G. Cellular retinol-binding protein-1 is expressed by distinct subsets of rat arterial smooth muscle cells in vitro and in vivo. Am J Pathol. 1997;150:509-521.
    • (1997) Am J Pathol. , vol.150 , pp. 509-521
    • Neuville, P.1    Geinoz, A.2    Benzonana, G.3    Redard, M.4    Gabbiani, F.5    Ropraz, P.6    Gabbiani, G.7
  • 24
    • 0026540611 scopus 로고
    • Cultured aortic smooth muscle cells from newborn and adult rats show distinct cytoskeletal features
    • Bochaton-Piallat M, Gabbiani F, Ropraz P, Gabbiani G. Cultured aortic smooth muscle cells from newborn and adult rats show distinct cytoskeletal features. Differentiation. 1992;49:175-185.
    • (1992) Differentiation , vol.49 , pp. 175-185
    • Bochaton-Piallat, M.1    Gabbiani, F.2    Ropraz, P.3    Gabbiani, G.4
  • 25
    • 0028064729 scopus 로고
    • Protein kinase C activation inhibits cytokine-induced nitric oxide synthesis in vascular smooth muscle cells
    • Geng YJ, Wu Q, Hansson GK. Protein kinase C activation inhibits cytokine-induced nitric oxide synthesis in vascular smooth muscle cells. Biochim Biophvs Acta. 1994;1223:125-132.
    • (1994) Biochim Biophvs Acta , vol.1223 , pp. 125-132
    • Geng, Y.J.1    Wu, Q.2    Hansson, G.K.3
  • 26
    • 0027255749 scopus 로고
    • Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon-γand bacterial lipopolysaccharide
    • Xie QW, Whisnant R, Nathan C. Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon-γand bacterial lipopolysaccharide. J Exp Med. 1993;177: 1779-1784.
    • (1993) J Exp Med. , vol.177 , pp. 1779-1784
    • Xie, Q.W.1    Whisnant, R.2    Nathan, C.3
  • 27
    • 0029130938 scopus 로고
    • Oxidized LDL induces transcription factor activator protein-1 but inhibits activation of nuclear factor-κB in human vascular smooth muscle cells
    • Ares MP, Kallin B, Eriksson P, Nilsson J. Oxidized LDL induces transcription factor activator protein-1 but inhibits activation of nuclear factor-κB in human vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 1995;15:1584-1590.
    • (1995) Arterioscler Thromb Vasc Biol. , vol.15 , pp. 1584-1590
    • Ares, M.P.1    Kallin, B.2    Eriksson, P.3    Nilsson, J.4
  • 28
    • 0026590541 scopus 로고
    • Dithiocarbamates as potent inhibitors of nuclear factor κB activation in intact cells
    • Schreck R, Meier B, Mannel DN, Droge W, Baeuerle PA. Dithiocarbamates as potent inhibitors of nuclear factor κB activation in intact cells. J Exp Med. 1992;175:1181-1194.
    • (1992) J Exp Med. , vol.175 , pp. 1181-1194
    • Schreck, R.1    Meier, B.2    Mannel, D.N.3    Droge, W.4    Baeuerle, P.A.5
  • 29
    • 0028148227 scopus 로고
    • A proteasome inhibitor prevents activation of NF- B and stabilizes a newly phosphorylated form of IκB-α that is still bound to NF-κB
    • Traenckner EB, Wilk S, Baeuerle PA. A proteasome inhibitor prevents activation of NF- B and stabilizes a newly phosphorylated form of IκB-α that is still bound to NF-κB. EMBO J. 1994;13:5433-5441.
    • (1994) EMBO J. , vol.13 , pp. 5433-5441
    • Traenckner, E.B.1    Wilk, S.2    Baeuerle, P.A.3
  • 30
    • 0031022516 scopus 로고    scopus 로고
    • An interferon- γ-activated site (gas) is necessary for full expression of the mouse iNOS gene in response to interferon-γ and lipopolysaccharide
    • Gao JJ, Morrison DC, Parmely TJ, Russell SW, Murphy WJ. An interferon- γ-activated site (gas) is necessary for full expression of the mouse iNOS gene in response to interferon-γ and lipopolysaccharide. J Biol Chem. 1997;272:1226-1230.
    • (1997) J Biol Chem. , vol.272 , pp. 1226-1230
    • Gao, J.J.1    Morrison, D.C.2    Parmely, T.J.3    Russell, S.W.4    Murphy, W.J.5
  • 31
    • 0027267486 scopus 로고
    • Generation of nitnc oxide and induction of major histocompatibility complex class II antigen in macrophages from mice lacking the interferon-γ receptor
    • Kamijo R, Shapiro D, Le J, Huang S, Aguet M, Vilcek J. Generation of nitnc oxide and induction of major histocompatibility complex class II antigen in macrophages from mice lacking the interferon-γ receptor. Proc Natl Acad Sci U S A. 1993;90:6626-6630.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 6626-6630
    • Kamijo, R.1    Shapiro, D.2    Le, J.3    Huang, S.4    Aguet, M.5    Vilcek, J.6
  • 32
    • 0026052725 scopus 로고
    • Cloning of the human gene for intercellular adhesion molecule 1 and analysis of its 5′-regulatory region: Induction by cytokines and phorbol ester
    • Voraberger G, Schafer R, Stratowa C. Cloning of the human gene for intercellular adhesion molecule 1 and analysis of its 5′-regulatory region: induction by cytokines and phorbol ester. J Immunol. 1991;147: 2777-2786.
    • (1991) J Immunol. , vol.147 , pp. 2777-2786
    • Voraberger, G.1    Schafer, R.2    Stratowa, C.3
  • 33
    • 0030610362 scopus 로고    scopus 로고
    • A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
    • DiDonato JA, Hayakawa M, Rothwarf DM, Zandi E, Karin M. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB. Nature. 1997;388:548-554.
    • (1997) Nature , vol.388 , pp. 548-554
    • DiDonato, J.A.1    Hayakawa, M.2    Rothwarf, D.M.3    Zandi, E.4    Karin, M.5
  • 35
    • 0030611595 scopus 로고    scopus 로고
    • IκB kinase-β: NF-κB activation and complex formation with IκB kinase-α and NIK
    • Woronicz JD, Gao X, Cao Z, Rothe M, Goeddel DV. IκB kinase-β: NF-κB activation and complex formation with IκB kinase-α and NIK. Science. 1997;278:866-869.
    • (1997) Science , vol.278 , pp. 866-869
    • Woronicz, J.D.1    Gao, X.2    Cao, Z.3    Rothe, M.4    Goeddel, D.V.5
  • 36
    • 0028985190 scopus 로고
    • Phosphorylation of IκBα precedes but is not sufficient for its dissociation from NF-κB
    • DiDonato JA, Mercurio F, Karin M. Phosphorylation of IκBα precedes but is not sufficient for its dissociation from NF-κB. Mol Cell Biol. 1995;15:1302-1311.
    • (1995) Mol Cell Biol. , vol.15 , pp. 1302-1311
    • DiDonato, J.A.1    Mercurio, F.2    Karin, M.3
  • 37
    • 0028172869 scopus 로고
    • Inducible phosphorylalion of IκBα is not sufficient for its dissociation from NF-κB and is inhibited by protease inhibitors
    • Finco TS, Beg AA, Baldwin AJ. Inducible phosphorylalion of IκBα is not sufficient for its dissociation from NF-κB and is inhibited by protease inhibitors. Proc Natl Acad Sci U S A. 1994;91:11884-11888.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 11884-11888
    • Finco, T.S.1    Beg, A.A.2    Baldwin, A.J.3
  • 39
    • 0025965439 scopus 로고
    • Modulation of coronary vasomotor tone in humans: Progressive endothelial dysfunction with different early stages of coronary atherosclerosis
    • Zeiher AM, Drexler H, Wollschlager H, Just H. Modulation of coronary vasomotor tone in humans: progressive endothelial dysfunction with different early stages of coronary atherosclerosis. Circulation. 1991;83: 391-401.
    • (1991) Circulation , vol.83 , pp. 391-401
    • Zeiher, A.M.1    Drexler, H.2    Wollschlager, H.3    Just, H.4
  • 41
    • 0028786601 scopus 로고
    • A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter
    • Melillo G, Musso T, Sica A, Taylor LS, Cox GW, Varesio L. A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter. J Exp Med. 1995;182: 1683-1693.
    • (1995) J Exp Med. , vol.182 , pp. 1683-1693
    • Melillo, G.1    Musso, T.2    Sica, A.3    Taylor, L.S.4    Cox, G.W.5    Varesio, L.6
  • 42
    • 0028058917 scopus 로고
    • Cytokine-induced expression of nitric oxide synthase results in nitrosylation of heme and nonheme iron proteins in vascular smooth muscle cells
    • Geng YJ, Petersson AS, Wennmalm A, Hansson GK. Cytokine-induced expression of nitric oxide synthase results in nitrosylation of heme and nonheme iron proteins in vascular smooth muscle cells. Exp Cell Res. 1994;214:418-428.
    • (1994) Exp Cell Res. , vol.214 , pp. 418-428
    • Geng, Y.J.1    Petersson, A.S.2    Wennmalm, A.3    Hansson, G.K.4
  • 44
    • 0029671119 scopus 로고    scopus 로고
    • Age-associated differences in TNF-α and nitric oxide production in endotoxic mice
    • Chorinchath BB, Kong LY, Mao L, McCallum RE. Age-associated differences in TNF-α and nitric oxide production in endotoxic mice. J Immunol. 1996;156:1525-1530.
    • (1996) J Immunol. , vol.156 , pp. 1525-1530
    • Chorinchath, B.B.1    Kong, L.Y.2    Mao, L.3    McCallum, R.E.4
  • 45
    • 0028200179 scopus 로고
    • Arterial smooth muscle cells express nitric oxide synthase in response to endothelial injury
    • Hansson GK, Geng YJ, Holm J, Hardhammar P, Wennmalm A, Jennische E. Arterial smooth muscle cells express nitric oxide synthase in response to endothelial injury. J Exp Med. 1994;180:733-738.
    • (1994) J Exp Med. , vol.180 , pp. 733-738
    • Hansson, G.K.1    Geng, Y.J.2    Holm, J.3    Hardhammar, P.4    Wennmalm, A.5    Jennische, E.6
  • 46
    • 0029895815 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase is present within human atherosclerotic lesions and promotes the formation and activity of peroxynitrite
    • Buttery L, Springall DR, Chester AH, Evans TJ, Standfield N, Parums DV, Yacoub MH, Polak JM. Inducible nitric oxide synthase is present within human atherosclerotic lesions and promotes the formation and activity of peroxynitrite. Lab Invest. 1996;75:77-85.
    • (1996) Lab Invest. , vol.75 , pp. 77-85
    • Buttery, L.1    Springall, D.R.2    Chester, A.H.3    Evans, T.J.4    Standfield, N.5    Parums, D.V.6    Yacoub, M.H.7    Polak, J.M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.