Adaptive mechanisms to oxidative stress during aging

Mechanisms of Ageing and Development

Volumn 127, Issue 5, 2006, Pages 436-443

  Yu, Byung Pal ^a,b   Chung, Hae Young ^b,c  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b Longevity Life Science and Technology Institutes   (South Korea)

^c Pusan National University   (South Korea)

Author keywords

Aging; Exercise; Gene regulation; Inflammation; Mitochondrial uncoupling; NF B; Oxidative stress; p66; PPARs; Transcription factors

Indexed keywords

CATALASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PROTEIN P66; SUPEROXIDE DISMUTASE;

ADAPTATION; AGING; ARTICLE; DEFENSE MECHANISM; EXERCISE; GENE CONTROL; HUMAN; MITOCHONDRION; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL;

AGING; ANIMALS; EVOLUTION, MOLECULAR; EXERCISE; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; MITOCHONDRIA; NF-KAPPA B; OXIDATIVE STRESS; OXYGEN; TRANSCRIPTION, GENETIC;

EID: 33645870996     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2006.01.023     Document Type: Article

References (67)

1. Beckman K.B., and Ames B.N. The free radical theory of aging nature. Physiol. Rev. 78 (1998) 547-581
2. Beutnner G.R. The pecking order of free radicals and antioxidants: lipid peroxidation, alpha-tocopherol, and ascorbate. Arch. Biochim. Biophys. 300 (1993) 535-543
3. Borras C., Sastre J., Garcia-Sala D., Lloret A., Pallardo F.V., and Vina J. Mitochondria from females exhibit higher antioxidant gene expression and lower oxidative damage than males. Free Rad. Bio. Med. 34 (2003) 546-552
4. Brand M.D. Uncoupling to survive? The role of mitochondrial inefficiency in aging. Exp. Gerontol. 35 (2000) 811-820
5. Bronikowski A.M., Carther P.A., Morgan T.J., Garland T., Ung N., Pugh T., Weindruch R., and Prolla T.A. Lifelong voluntary exercise in the mouse prevents age-related alterations in gene expression in the heart. Physiol. Genomics. 12 (2003) 129-138
6. Brown-Borg H.M., and Rakoczy S.G. Glutathione metabolism in long-living Ames dwarf mice. Exp. Geront. 40 (2005) 115-120
7. Cho C.G., Kim H.J., Chung S.W., Shim K.H., Yu B.P., Yodori J., and Chung H.Y. Modulation of glutathione and thioredoxine systems by calorie restriction during aging process. Exp. Gerontol. 38 (2003) 539-548
8. Chow, C.K. (Ed.), Interrelationships of cellular antioxidant defense systems. In: Cellular Antioxidant Defense Mechanisms, vol. 2. CRC Press, Boca Raton, 1988, pp. 217-237.
9. Chung H.Y., Kim H.J., Kim W.J., and Yu B.P. The inflammatory hypothesis of aging: molecular modulation by calorie restriction. Ann. NY Acad. Sci. 928 (2001) 327-335
10. Chung H.Y., Kim H.J., Kim K.W., Choi J.S., and Yu B.P. Molecular inflammation hypothesis based on the anti-aging mechanism of calorie restriction. Microsc. Res. Tech. 59 (2002) 264-272
11. Chung H.Y., Jung K.J., and Yu B.P. Molecular inflammation as an underlying mechanism of aging: The anti-inflammatory action of calorie restriction. In: Surh Y.J., and Packer L. (Eds). Oxidative stress, Inflammation and Health (2005), Marcel Dekker, NY 387-419
12. Cook C.I., and Yu B.P. Iron accumulation in aging: modulation by dietary restriction. Mech. Ageing Dev. 102 (1998) 1-13
13. Crawford D.R., and Cerutti P.A. Expression of oxidant stress-related genes in tumor promotion of mouse epidermal JB6 cells. In: Nyggard O.F. (Ed). Proceedings of the Second Conference on Anticarcinogens and Radioprotectors. Plenum Press, NY (1987) 183-190
14. Devi S.A., and Kiran T.R. Regional responses in antioxidant system to exercise training and dietary Vitamin E in aging rat brain. Neurobiol. Aging 25 (2004) 501-508
15. Echtay K.S., Roussel D., St-Pierre J., Jekabsons M.B., Cadenas S., Stuart J.A., Harper J.A., Roebuck S.J., Morrison A., Pickering S., Clapham J.C., and Brand M.D. Superoxide activates mitochondrial uncoupling proteins. Nature 415 (2002) 96-99
16. Ferrucci L., Ble A., Bandinelli S., Lauretani F., Suthers K., and Guralnik J.M. A flame burning within. Aging Clin. Exp. Res. 16 (2004) 240-243
17. Fisher A.B., Forman H.J., and Glass A. Mechanism of pulmonary oxygen toxicity. Lung 162 (1981) 255-259
18. Francia P., delli Gatti C., Bachschmid M., Martin-Padura I., Savoia C., Migliaccio E., Pelicci P.G., Schiavoni M., Luscher T.F., Volpe M., and Cosentino F. Deletion of p66shc gene protects against age-related endothelial dysfunction. Circulation 110 (2004) 2889-2895
19. Fulle S., Protasi F., Di Tano G., Pietrangelo T., Beltramin A., Boncompagni S., Vecchiet L., and Fano G. The contribution of reactive oxygen species to sarcopenia and muscle ageing. Exp. Gerontol. 39 (2004) 17-24
20. Golden T.R., Hinerfeld D.A., and Melov S. Oxidative stress and aging: beyond correlation. Aging Cell 2 (2002) 117-123
21. Goto S., Radak Z., Nyakas C., Chung H.Y., Naito H., Takahashi R., Nakamoto H., and Abea R. Regular exercise: an effective means to reduce oxidative stress in old rats. Ann. NY Acad. Sci. 1019 (2004) 471-474
22. Harman D. Role of free radicals in aging and disease. In: Johnson H.A. (Ed). Relations between Normal Aging and Disease (1985), Raven Press, New York 45-84
23. Holzenberger M., Dupont J., Ducos B., Leneuve P., Geloen A., Evan P.C., Cervera P., and le Bouc Y. IGF-1 receptor regulated lifespan and resistance to oxidative stress on mice. Nature 421 (2003) 182-187
24. Je J.H., Lee J.Y., Jung K.J., Sung B., Go E.K., Yu B.P., and Chung H.Y. NF-kappaB activation mechanism of 4-hydroxyhexanal via NIK/IKK and p38 MARK pathway. FEBS Lett. 566 (2004) 183-189
25. Jenkins R.R., Krause K., and Scofield L.S. Influence of exercise on clearance of oxidant stress products and loosely bound iron. Med. Sci. Sports Exerc. 25 (1993) 213-217
26. Jenkins R.R. Exercise and oxidative stress methodology: a critique. Am. J. Clin. Nutr. 72 (2000) 670s-674s
27. Ji L.L. Antioxidant enzyme response to exercise and aging. Med. Sci. Sports Exerc. 25 (1993) 225-231
28. Holliday R. Understanding Ageing (1995), Cambridge University Press
29. Martin G.M., Austad S.N., and Johnson T.E. Genetic analysis of aging: role of oxidative damage and environmental stresses. Nat. Genet. 13 (1996) 25-34
30. Massabuau J.-C. Primitive, and protective, our cellular oxygenation status?. Mech. Ageing Dev. 124 (2003) 857-863
31. Merry B.J. Molecular mechanisms linking calorie restriction and longevity. Intl. J. Biochem. Cell Biol. 34 (2002) 1340-1354
32. Migliaccio E., Giorgio M., Mele S., Pelicci G., Reboldi P., Pandolfi P.P., Lanfranconne L., and Pelicci P.G. The p66shc adaptor protein controls oxidative stress response and life span in mammals. Nature 402 (1999) 243-245
33. Killilea D.W., Wong S.L., Cahaya H.S., Atamna H., and Ames B.N. Iron accumulation during cellular senescence. Ann. NY Acad. Sci. 1019 (2004) 365-367
34. Kim C.H., Park D.H., Chung A., Zou Y., Jung K.J., Sung B.K., Yu B.P., and Chung H.Y. Proteomic analysis of post-mitochondrial fractions of young and old rat kidney. Exp. Geront. 39 (2004) 1155-1168
35. Kim H.J., Kim K.W., Yu B.P., and Chung H.Y. The effect of age on cyclooxygenases-2 gene expression: NFkB activation and IKBa degradation. Free Rad. Biol. Med. 28 (2000) 683-692
36. Kim H.J., Yu B.P., and Chung H.Y. Molecular exploration of age-related NFkB/IKK downregulation by calorie restriction in rat kidney. Free Rad. Biol. Med. 32 (2002) 991-1005
37. Kim H.J., Jung K.J., Yu B.P., Cho C.G., and Chung H.Y. Influence of aging and calorie restriction on MAPK activity in rat kidney. Exp. Gerontol. 37 (2002) 1041-1053
38. Lane N. A unifying view of ageing and disease: the double-agent theory. J. Theor. Biol. 225 (2003) 531-540
39. Lee J.Y., Je J.H., Yu B.P., and Chung H.Y. Induction of endothelial iNOS by 4-hydroxyhexanal through NF-kB activation. Free Rad. Biol. Med. 37 (2004) 539-548
40. Leonard S.S., Harris G.K., and Shi X. Metal-induced oxidative and signal transduction. Free Rad. Biol. Med. 37 (2004) 1921-1942
41. Luquet S., lopez-Soriano J., Holst D., Fredenrich A., Melki J., Rassoulzadegan M., and Grimaldi P.A. Peroxisome proliferator-activated receptor delta controls muscle development and oxidative capacity. FASEB J. 15 (2003) 2299-2301
42. Park D.U., Lee J.H., Kim H.J., Kim C.H., Hong S.E., Chang G.Y., Yu B.P., and Chung H.Y. Aging DB: Aging database for oxidative stress, calorie restriction in the aging study. J. Am. Aging Assoc. 26 (2003) 11-18
43. Park S.K., and Prolla T. Lessons learned from gene expression profile studies of aging and calorie restriction. Ageing Rev. Res. 4 (2005) 55-65
44. Parson P.A. The limit to human longevity: an approach through a stress theory of ageing. Mech. Ageing Dev. 87 (1996) 211-218
45. Poon H.F., Calabrese V., Scapagnini G., and Butterfield D.A. Free radicals and brain aging. Clin. Geriatr. Med. 20 (2004) 329-359
46. Poynter M.E., and Daynes R.A. Peroxisome proliferator-activated receptor alpha activation modulates cellular redox status, represses nuclear factor-kappa signaling, and reduces inflammatory cytokine production in aging. J. Biol. Chem. 273 (1998) 32833-32841
47. Shc: at the crossroad of oxidative stress and the genetics of aging. Trends Mol. Med. 9 (2003) 206-210
48. Radak Z., Kaneko T., Tahara S., Nakamoto H., Ohno H., Sasvari M., Nyakas C., and Goto S. The effect of exercise training on oxidative damage of lipids, proteins, and DNA in rat skeletal muscle: evidence for beneficial outcomes. Free Rad. Biol. Med. 27 (1999) 69-74
49. Radak Z., Taylor A.W., Ohno H., and Goto S. Adaptation to exercise-induced oxidative stress: from muscle to brain. Exerc. Immunol. Rev. 7 (2001) 90-107
50. Radak Z., Naito H., Kaneko T., Tahara S., Nakamoto H., Takahashi R., Cardozo-Pelaez F., and Goto S. Exercise training decreases DNA damage and increases DNA repair and resistance against oxidative stress of proteins in aged rat skeletal muscle. Pflugers. Arch. 445 (2002) 273-278
51. Radak Z., Chung H.Y., Naito H., Takahash R., Jung K.J., Kim H.J., and Goto S. Age-associated increase in oxidative stress and nuclear factor kappaB activation are attenuated in rat liver by regular exercise. FASEB J. 18 (2004) 749-750
52. Sagi O., Wolfson M., Utko N., Muradian K., and Fraifeld V. P66(ShcA) and ageing: modulation by longevity-promoting agent aurintricarboxylic acid. Mech. Ageing Dev. 126 (2005) 249-254
53. Shimokawa I., Higami Y., Utsuyama M., Tuchiya T., Komatsu T., Chiba T., and Yamaza H. Life span extension by reduction in growth hormone-insulin-like growth factor-1 axis in a transgenic rat model. Am. J. Pathol. 160 (2002) 2259-2265
54. Sies, H. (Ed.), Oxidative stress: introductory remarks. In: Oxidative Stress. Academic Press, Orlando, FL, 1985, pp. 1-8.
55. Speakman J.R., Talbot D.A., Selman C., Snart S., McLaren J.S., Redman P., Krol E., Jackson D.M., Johnson M.S., and Brand M.D. Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer. Aging Cell 3 (2004) 87-95
56. Sung B.K., Park S., Yu B.P., and Chung H.Y. Modulation of PPAR in aging, inflammation and calorie restriction. J. Geront. 59 (2004) B997-B1006
57. Suzuki T., Spitz D.R., Grandhi P., Lin H.Y., and Crawford D.R. Mammalian resistance to oxidative stress: a comparative analysis. Gene Expr. 10 (2002) 179-191
58. Vanden Berghe W., Vermeulen L., Delerive P., De Bosscher K., Staels B., and Haegeman G. A paradigm for gene regulation; inflammation, NF-kappaB and PPAR. Adv. Exp. Med. Biol. 544 (2003) 181-196
59. Wahli W. peroxisome proliferator-activated receptors (PPARs): from metabolic control to epidermal wound healing. Swiss Med. Wkly. 132 (2002) 83-91
60. Weindruch R., Kayo T., Lee C.K., and Prolla T.A. Gene expression profiling of aging using DNA microarrays. Mech. Ageing Dev. 123 (2002) 177-193
61. Yoon S.O., Yun C.H., and Chung A.S. Dose effect of oxidative stress on signal transduction in aging. Mech. Ageing Dev. 123 (2002) 1597-1604
62. Yu B.P. Cellular defenses against damage from reactive oxygen species. Physiol. Rev. 74 (1994) 139-162
63. Yu B.P., and Yang R. Critical evaluation of free radical theory of aging: a proposal of oxidative stress hypothesis. Ann. NY Acad. Sci. 786 (1996) 1-11
64. Yu B.P., and Chung H.Y. Oxidative stress and vascular aging. Diabetes Res. Clin. Pract. 54 Suppl. 2 (2001) S73-S80
65. Yu B.P., and Chung H.Y. Stress resistance by calorie restriction for longevity. Ann. NY Acad. Sci. 928 (2001) 39-47
66. Yu B.P. Calorie restriction as a potent anti-aging intervention: suppression of oxidative stress. In: Rattan, and Suresh (Eds). Aging Intervention and Therapies (2005), World Science Publishers 193-217
67. Zou Y., Jung K.J., Kim J.W., Yu B.P., and Chung H.Y. Alteration of soluble adhesion molecules during aging and their modulation by calorie restriction. FASEB J. 18 (2004) 320-322