Nrf2 regulates hyperoxia-induced Nox4 expression in human lung endothelium: Identification of functional antioxidant response elements on the Nox4 promoter

Free Radical Biology and Medicine

Volumn 50, Issue 12, 2011, Pages 1749-1759

  Pendyala, Srikanth ^a   Moitra, Jaideep ^b   Kalari, Satish ^c   Kleeberger, Steven R ^d   Zhao, Yutong ^e   Reddy, Sekhar P ^f   Garcia, Joe G N ^a   Natarajan, Viswanathan ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b Gennova Biopharmaceuticals Limited   (India)

^c CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^e UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^f JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

ARE; Endothelium; Free radicals; Nox4; Nrf2; ROS

Indexed keywords

REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NRF2;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CELL MIGRATION; CELL NUCLEUS; CHROMATIN IMMUNOPRECIPITATION; COMPUTER MODEL; CONSENSUS SEQUENCE; CONTROLLED STUDY; CYTOPLASM; FEMALE; GENE ACTIVITY; GENE DELETION; GENE SILENCING; HUMAN; HUMAN CELL; HYPEROXIA; LUNG ENDOTHELIUM; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTON TRANSPORT; REGULATORY MECHANISM; TRANSIENT TRANSFECTION;

ANIMALS; CELL MOVEMENT; CELLS, CULTURED; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; FREE RADICALS; HUMANS; HYDROGEN PEROXIDE; HYPEROXIA; LUNG; MICE; MICE, KNOCKOUT; NADPH OXIDASE; NF-E2-RELATED FACTOR 2; REACTIVE OXYGEN SPECIES; RESPONSE ELEMENTS; RNA, SMALL INTERFERING; SUPEROXIDES;

MUS;

EID: 79956121323     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.03.022     Document Type: Article

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