메뉴 건너뛰기




Volumn 3, Issue 10, 2011, Pages 913-919

Deciphering the role of nuclear factor-κB in cellular senescence

Author keywords

Ageing; Cellular senescence; NF b; SASP

Indexed keywords


EID: 80855165243     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100390     Document Type: Article
Times cited : (63)

References (62)
  • 2
    • 14644410453 scopus 로고    scopus 로고
    • The signals and pathways activating cellular senescence
    • Ben-Porath I, Weinberg RA. The signals and pathways activating cellular senescence. Int J Biochem Cell Biol. 2005; 37: 961-976.
    • (2005) Int J Biochem Cell Biol , vol.37 , pp. 961-976
    • Ben-Porath, I.1    Weinberg, R.A.2
  • 3
    • 34548186667 scopus 로고    scopus 로고
    • Cellular senescence: when bad things happen to good cells
    • Campisi J, d'Adda di Fagagna F. Cellular senescence: when bad things happen to good cells. Nat Rev Mol Cell Biol. 2007; 8: 729-740.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 729-740
    • Campisi, J.1    d'Adda di Fagagna, F.2
  • 4
    • 70349773104 scopus 로고    scopus 로고
    • Healing and hurting: molecular mechanisms, functions, and pathologies of cellular senescence
    • Adams PD. Healing and hurting: molecular mechanisms, functions, and pathologies of cellular senescence. Mol Cell. 2009; 36: 2-14.
    • (2009) Mol Cell , vol.36 , pp. 2-14
    • Adams, P.D.1
  • 5
    • 67649424560 scopus 로고    scopus 로고
    • p21 in cancer: intricate networks and multiple activities
    • Abbas T, Dutta A. p21 in cancer: intricate networks and multiple activities. Nat Rev Cancer. 2009; 9: 400-14.
    • (2009) Nat Rev Cancer , vol.9 , pp. 400-414
    • Abbas, T.1    Dutta, A.2
  • 6
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011; 144:646-74.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 7
    • 79952269372 scopus 로고    scopus 로고
    • DNA damaging agents and p53 do not cause senescence in quiescent cells, while consecutive re-activation of mTOR is associated with conversion to senescence
    • Leontieva OV, Blagosklonny MV. DNA damaging agents and p53 do not cause senescence in quiescent cells, while consecutive re-activation of mTOR is associated with conversion to senescence. Aging (Albany NY). 2010; 2:924-35.
    • (2010) Aging (Albany NY) , vol.2 , pp. 924-935
    • Leontieva, O.V.1    Blagosklonny, M.V.2
  • 8
    • 79957880743 scopus 로고    scopus 로고
    • Cell cycle arrest is not senescence
    • Blagosklonny MV. Cell cycle arrest is not senescence. Aging (Albany NY). 2011; 3:94-101.
    • (2011) Aging (Albany NY) , vol.3 , pp. 94-101
    • Blagosklonny, M.V.1
  • 9
    • 80655140442 scopus 로고    scopus 로고
    • Progeria, rapamycin and normal aging:recent breakthrough
    • Blagosklonny MV. Progeria, rapamycin and normal aging:recent breakthrough. Aging (Albany NY). 2011; 3:685-91.
    • (2011) Aging (Albany NY) , vol.3 , pp. 685-691
    • Blagosklonny, M.V.1
  • 10
    • 38849199203 scopus 로고    scopus 로고
    • Shared principles in NF-kappaB signaling
    • Hayden MS, Ghosh S. Shared principles in NF-kappaB signaling. Cell. 2008; 132: 344-362.
    • (2008) Cell , vol.132 , pp. 344-362
    • Hayden, M.S.1    Ghosh, S.2
  • 11
    • 33750443289 scopus 로고    scopus 로고
    • IkappaB kinase complexes: gateways to NFkappaB activation and transcription
    • Scheidereit C. IkappaB kinase complexes: gateways to NFkappaB activation and transcription. Oncogene. 2006; 25: 6685- 6705.
    • (2006) Oncogene , vol.25 , pp. 6685-6705
    • Scheidereit, C.1
  • 15
    • 0035379555 scopus 로고    scopus 로고
    • Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38
    • Madrid LV, Mayo MW, Reuther JY, Baldwin AS Jr. Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38. J Biol Chem. 2001; 276:18934-40.
    • (2001) J Biol Chem , vol.276 , pp. 18934-18940
    • Madrid, L.V.1    Mayo, M.W.2    Reuther, J.Y.3    Baldwin Jr., A.S.4
  • 16
    • 74449090245 scopus 로고    scopus 로고
    • Insulin/IGF-1 paradox of aging: regulation via AKT/IKK/NF-kappaB signaling
    • Salminen A, Kaarniranta K. Insulin/IGF-1 paradox of aging: regulation via AKT/IKK/NF-kappaB signaling. Cell Signal. 2010; 22: 573-577.
    • (2010) Cell Signal , vol.22 , pp. 573-577
    • Salminen, A.1    Kaarniranta, K.2
  • 17
    • 77953859606 scopus 로고    scopus 로고
    • NF-kappaB as a critical link between inflammation and cancer
    • Karin M. NF-kappaB as a critical link between inflammation and cancer. Cold Spring Harb Perspect Biol. 2009; 1: a000141.
    • (2009) Cold Spring Harb Perspect Biol , vol.1
    • Karin, M.1
  • 19
  • 22
    • 41049114747 scopus 로고    scopus 로고
    • How to make a melanoma: what do we know of the primary clonal events?
    • Bennett DC. How to make a melanoma: what do we know of the primary clonal events? Pigment Cell Melanoma Res. 2008; 21:27-38.
    • (2008) , vol.21 , pp. 27-38
    • Bennett, D.C.1
  • 24
    • 67349284299 scopus 로고    scopus 로고
    • Chronic NFkappaB activation delays RasV12-induced premature senescence of human fibroblasts by suppressing the DNA damage checkpoint response
    • Batsi C, Markopoulou S, Vartholomatos G, Georgiou I, Kanavaros P, Gorgoulis VG, Marcu KB, Kolettas E. Chronic NFkappaB activation delays RasV12-induced premature senescence of human fibroblasts by suppressing the DNA damage checkpoint response. Mech Ageing Dev. 2009; 130: 409-419.
    • (2009) Mech Ageing Dev , vol.130 , pp. 409-419
    • Batsi, C.1    Markopoulou, S.2    Vartholomatos, G.3    Georgiou, I.4    Kanavaros, P.5    Gorgoulis, V.G.6    Marcu, K.B.7    Kolettas, E.8
  • 25
    • 48549099463 scopus 로고    scopus 로고
    • Cell autonomous expression of inflammatory genes in biologically aged fibroblasts associated with elevated NF-kappaB activity
    • Kriete A, Mayo KL, Yalamanchili N, Beggs W, Bender P, Kari C, Rodeck U. Cell autonomous expression of inflammatory genes in biologically aged fibroblasts associated with elevated NF-kappaB activity." Immun Ageing. 2008; 5: 5.
    • (2008) "Immun Ageing , vol.5 , pp. 5
    • Kriete, A.1    Mayo, K.L.2    Yalamanchili, N.3    Beggs, W.4    Bender, P.5    Kari, C.6    Rodeck, U.7
  • 26
    • 0242606930 scopus 로고    scopus 로고
    • A unifying view of ageing and disease: the doubleagent theory
    • Lane N. A unifying view of ageing and disease: the doubleagent theory. J Theor Biol. 2003; 225: 531-540.
    • (2003) J Theor Biol , vol.225 , pp. 531-540
    • Lane, N.1
  • 27
    • 40949123149 scopus 로고    scopus 로고
    • Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging
    • Salminen A, Huuskonen J, Ojala J, Kauppinen A, Kaarniranta K, Suuronen T. Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging. Ageing Res Rev. 2008; 7: 83-105.
    • (2008) Ageing Res Rev , vol.7 , pp. 83-105
    • Salminen, A.1    Huuskonen, J.2    Ojala, J.3    Kauppinen, A.4    Kaarniranta, K.5    Suuronen, T.6
  • 30
    • 79955017452 scopus 로고    scopus 로고
    • Campisi J. p38MAPK is a novel DNA damage response-independent regulator of the senescenceassociated secretory phenotype
    • Freund A, Patil CK, Campisi J. p38MAPK is a novel DNA damage response-independent regulator of the senescenceassociated secretory phenotype. EMBO J. 2011; 30: 1536-1548.
    • (2011) EMBO J , vol.30 , pp. 1536-1548
    • Freund, A.1    Patil, C.K.2
  • 32
    • 70449102637 scopus 로고    scopus 로고
    • A nuclear poly[ADP-ribose]-dependent signalosome confers DNA damage-induced IkappaB kinase activation
    • Stilmann M, Hinz M, Arslan SC, Zimmer A, Schreiber V, Scheidereit C. A nuclear poly[ADP-ribose]-dependent signalosome confers DNA damage-induced IkappaB kinase activation. Mol Cell. 2009; 36: 365-78.
    • (2009) Mol Cell , vol.36 , pp. 365-378
    • Stilmann, M.1    Hinz, M.2    Arslan, S.C.3    Zimmer, A.4    Schreiber, V.5    Scheidereit, C.6
  • 33
    • 77957333810 scopus 로고    scopus 로고
    • A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation
    • Hinz M, Stilmann M, Arslan SÇ, Khanna KK, Dittmar G, Scheidereit C. A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation. Mol Cell. 2010; 40: 63-74.
    • (2010) Mol Cell , vol.40 , pp. 63-74
    • Hinz, M.1    Stilmann, M.2    Arslan, Sç.3    Khanna, K.K.4    Dittmar, G.5    Scheidereit, C.6
  • 34
    • 33846128155 scopus 로고    scopus 로고
    • The DNA damage signaling pathway is a critical mediator of oncogeneinduced senescence
    • Mallette FA, Gaumont-Leclerc MF, Ferbeyre G. The DNA damage signaling pathway is a critical mediator of oncogeneinduced senescence. Genes & Development. 2007; 21: 43-48.
    • (2007) Genes & Development , vol.21 , pp. 43-48
    • Mallette, F.A.1    Gaumont-Leclerc, M.F.2    Ferbeyre, G.3
  • 35
    • 77949449274 scopus 로고    scopus 로고
    • Cellular senescence in the development and treatment of cancer
    • Saretzki G. Cellular senescence in the development and treatment of cancer. Curr Pharm Des. 2010; 16: 79-100.
    • (2010) Curr Pharm Des , vol.16 , pp. 79-100
    • Saretzki, G.1
  • 38
    • 40949123149 scopus 로고    scopus 로고
    • Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging
    • Salminen A, Huuskonen J, Ojala J, Kauppinen A, Kaarniranta K, Suuronen T. Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging." Ageing Res Rev. 2008; 7: 83-105.
    • (2008) "Ageing Res Rev , vol.7 , pp. 83-105
    • Salminen, A.1    Huuskonen, J.2    Ojala, J.3    Kauppinen, A.4    Kaarniranta, K.5    Suuronen, T.6
  • 39
    • 43049128529 scopus 로고    scopus 로고
    • Tenets of PTEN tumor suppression
    • Salmena L, Carracedo A, Pandolfi PP. Tenets of PTEN tumor suppression. Cell. 2008; 133: 403-14.
    • (2008) Cell , vol.133 , pp. 403-414
    • Salmena, L.1    Carracedo, A.2    Pandolfi, P.P.3
  • 41
    • 3242719545 scopus 로고    scopus 로고
    • Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
    • Yeung F, Hoberg JE, Ramsey CS, Keller MD, Jones DR, Frye RA, Mayo MW. Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J. 2004; 23: 2369-2380.
    • (2004) EMBO J , vol.23 , pp. 2369-2380
    • Yeung, F.1    Hoberg, J.E.2    Ramsey, C.S.3    Keller, M.D.4    Jones, D.R.5    Frye, R.A.6    Mayo, M.W.7
  • 43
    • 78649482634 scopus 로고    scopus 로고
    • SIRT1: recent lessons from mouse models
    • Herranz D, Serrano M. SIRT1: recent lessons from mouse models. Nat Rev Cancer. 2010; 10:819-23.
    • (2010) Nat Rev Cancer , vol.10 , pp. 819-823
    • Herranz, D.1    Serrano, M.2
  • 44
    • 79959996690 scopus 로고    scopus 로고
    • An RNA interference screen for identifying downstream effectors of the p53 and pRB tumour suppressor pathways involved in senescence
    • Rovillain E, Mansfield L, Lord CJ, Ashworth A, Jat PS. An RNA interference screen for identifying downstream effectors of the p53 and pRB tumour suppressor pathways involved in senescence. BMC Genomics. 2011; 12: 355.
    • (2011) BMC Genomics , vol.12 , pp. 355
    • Rovillain, E.1    Mansfield, L.2    Lord, C.J.3    Ashworth, A.4    Jat, P.S.5
  • 46
    • 52049117181 scopus 로고    scopus 로고
    • The lysosomal transmembrane protein 9B regulates the activity of inflammatory signaling pathways
    • Dodeller F, Gottar M, Huesken D, Iourgenko V, Cenni B. The lysosomal transmembrane protein 9B regulates the activity of inflammatory signaling pathways. J Biol Chem. 2008; 283: 21487-21494.
    • (2008) J Biol Chem , vol.283 , pp. 21487-21494
    • Dodeller, F.1    Gottar, M.2    Huesken, D.3    Iourgenko, V.4    Cenni, B.5
  • 48
    • 69749084749 scopus 로고    scopus 로고
    • The receptor interacting protein 1 mediates a link between NFkappaB and PI3-kinase signaling
    • 1
    • Chauncey SS, Boothman DA, Habib AA. The receptor interacting protein 1 mediates a link between NFkappaB and PI3-kinase signaling. Cell Cycle. 2009 1; 8:2671-2.
    • (2009) Cell Cycle , vol.8 , pp. 2671-2672
    • Chauncey, S.S.1    Boothman, D.A.2    Habib, A.A.3
  • 49
  • 52
    • 58149171655 scopus 로고    scopus 로고
    • Sustained NF-kappaB activation produces a short-term cell proliferation block in conjunction with repressing effectors of cell cycle progression controlled by E2F or FoxM1
    • Penzo M, Massa PE, Olivotto E, Bianchi F, Borzi RM, Hanidu A, Li X, Li J, Marcu KB. Sustained NF-kappaB activation produces a short-term cell proliferation block in conjunction with repressing effectors of cell cycle progression controlled by E2F or FoxM1. J Cell Physiol. 2009; 218: 215-227.
    • (2009) J Cell Physiol , vol.218 , pp. 215-227
    • Penzo, M.1    Massa, P.E.2    Olivotto, E.3    Bianchi, F.4    Borzi, R.M.5    Hanidu, A.6    Li, X.7    Li, J.8    Marcu, K.B.9
  • 55
    • 38849168162 scopus 로고    scopus 로고
    • Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7
    • Wajapeyee N, Serra RW, Zhu X, Mahalingam M, Green MR. Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7. Cell. 2008; 132: 363-74.
    • (2008) Cell , vol.132 , pp. 363-374
    • Wajapeyee, N.1    Serra, R.W.2    Zhu, X.3    Mahalingam, M.4    Green, M.R.5
  • 58
    • 58849154235 scopus 로고    scopus 로고
    • Senescence-messaging secretome: SMS-ing cellular stress
    • Kuilman T, Peeper DS. Senescence-messaging secretome: SMS-ing cellular stress. Nat Rev Cancer. 2009; 9: 81-94.
    • (2009) Nat Rev Cancer , vol.9 , pp. 81-94
    • Kuilman, T.1    Peeper, D.S.2
  • 59
    • 77949881221 scopus 로고    scopus 로고
    • The senescenceassociated secretory phenotype: the dark side of tumor suppression
    • Coppé JP, Desprez PY, Krtolica A, Campisi J. The senescenceassociated secretory phenotype: the dark side of tumor suppression. Annu Rev Pathol. 2010; 5: 99-118.
    • (2010) Annu Rev Pathol , vol.5 , pp. 99-118
    • Coppé, J.P.1    Desprez, P.Y.2    Krtolica, A.3    Campisi, J.4
  • 60
    • 77954563804 scopus 로고    scopus 로고
    • Senescent cells as a source of inflammatory factors for tumor progression
    • Davalos AR, Coppe JP, Campisi J, Desprez PY. Senescent cells as a source of inflammatory factors for tumor progression. Cancer Metastasis Rev. 2010; 29:273-83.
    • (2010) Cancer Metastasis Rev , vol.29 , pp. 273-283
    • Davalos, A.R.1    Coppe, J.P.2    Campisi, J.3    Desprez, P.Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.