Reduced release of nitric oxide to shear stress in mesenteric arteries of aged rats

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 286, Issue 6 55-6, 2004, Pages

  Sun, Dong ^a   Huang, An ^a   Yan, Ellen H ^a   Wu, Zhiping ^a   Yan, Changdong ^a   Kaminski, Pawel M ^a   Oury, Tim D ^b   Wolin, Michael S ^a   Kaley, Gabor ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

Endothelium; Superoxide; Superoxide dismutase

Indexed keywords

ACETYLCHOLINE; COPPER ZINC SUPEROXIDE DISMUTASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; NITRATE; NITRIC OXIDE; NITRITE; SUPEROXIDE; SUPEROXIDE DISMUTASE; TIRON;

ADOLESCENT; AGED; AGING; ANIMAL TISSUE; ARTERIOLE; ARTERY ENDOTHELIUM; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; MALE; MESENTERIC ARTERIOLE; MESENTERIC ARTERY; NONHUMAN; PRIORITY JOURNAL; RAT; RESISTANCE BLOOD VESSEL; SHEAR STRESS; VASODILATATION;

AGING; ANIMALS; BLOOD PRESSURE; ENDOTHELIUM, VASCULAR; MALE; MESENTERIC ARTERIES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; RATS; RATS, INBRED F344; STRESS, MECHANICAL; SUPEROXIDE DISMUTASE; SUPEROXIDES; VASODILATION;

EID: 2542467787     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00854.2003     Document Type: Article

References (37)

1. Amrani M, Goodwin AT, Gray CC, and Yacoub MH. Ageing is associated with reduced basal and stimulated release of nitric oxide by the coronary endothelium. Acta Physiol Scand 157: 79-84, 1996.
2. Bonner FT. Nitric oxide gas. Methods Enzymol 268: 50-57, 1996.
3. Cai H and Harrison DG. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res 87: 840-844, 2000.
4. Celermajer DS, Sorensen KE, Spiegelhalter DJ, Georgakopoulos D, Robinson J, and Deanfield JE. Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women. J Am Coll Cardiol 24: 471-476, 1994.
5. Cernadas MR, Sanchez dM, Garcia-Duran M, Gonzalez-Fernandez F, Millas I, Monton M, Rodrigo J, Rico L, Fernandez P, de Frutos T, Rodriguez-Feo JA, Guerra J, Caramelo C, Casado S, and Lopez F. Expression of constitutive and inducible nitric oxide synthases in the vascular wall of young and aging rats. Circ Res 83: 279-286, 1998.
6. Challah M, Nadaud S, Philippe M, Battle T, Soubrier F, Corman B, and Michel JB. Circulating and cellular markers of endothelial dysfunction with aging in rats. Am J Physiol Heart Circ Physiol 273: H1941-H1948, 1997.
7. Csiszar A, Ungvari Z, Edwards JG, Kaminski P, Wolin MS, Koller A, and Kaley G. Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function. Circ Res 90: 1159-1166, 2002.
8. De Keulenaer GW, Chappell DC, Ishizaka N, Nerem RM, Alexander RW, and Griendling KK. Oscillatory and steady laminar shear stress differentially affect human endothelial redox state: role of a superoxide-producing NADH oxidase. Circ Res 82: 1094-1101, 1998.
9. Demchenko IT, Oury TD, Crapo JD, and Piantadosi CA. Regulation of the brain's vascular responses to oxygen. Circ Res 91: 1031-1037, 2002.
10. Didion SP, Ryan MJ, Didion LA, Fegan PE, Sigmund CD, and Faraci FM. Increased superoxide and vascular dysfunction in CuZnSOD-deficient mice. Circ Res 91: 938-944, 2002.
11. Fattman CL, Schaefer LM, and Oury TD. Extracellular superoxide dismutase in biology and medicine. Free Radic Biol Med 35: 236-256, 2003.
12. Gaballa MA, Jacob CT, Raya TE, Liu J, Simon B, and Goldman S. Large artery remodeling during aging: biaxial passive and active stiffness. Hypertension 32: 437-443, 1998.
13. Hamilton CA, Brosnan MJ, McIntyre M, Graham D, and Dominiczak AF. Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction. Hypertension 37: 529-534, 2001.
14. Hsieh HJ, Cheng CC, Wu ST, Chiu JJ, Wung BS, and Wang DL. Increase of reactive oxygen species (ROS) in endothelial cells by shear flow and involvement of ROS in shear-induced c-fos expression. J Cell Physiol 175: 156-162, 1998.
15. Huang A, Sun D, Kaley G, and Koller A. Superoxide released to high intra-arteriolar pressure reduces nitric oxide-mediated shear stress- and agonist-induced dilations. Circ Res 83: 960-965, 1998.
16. Landmesser U, Dikalov S, Price SR, McCann L, Fukai T, Holland SM, Mitch WE, and Harrison DG. Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension. J Clin Invest 111: 1201-1209, 2003.
17. Landmesser U, Merten R, Spiekermann S, Buttner K, Drexler H, and Hornig B. Vascular extracellular superoxide dismutase activity in patients with coronary artery disease: relation to endothelium-dependent vasodilation. Circulation 101: 2264-2270, 2000.
18. Landmesser U, Spiekermann S, Dikalov S, Tatge H, Wilke R, Kohler C, Harrison DG, Hornig B, and Drexler H. Vascular oxidative stress and endothelial dysfunction in patients with chronic heart failure: role of xanthine-oxidase and extracellular superoxide dismutase. Circulation 106: 3073-3078, 2002.
19. MacMillan-Crow LA, Crow JP, and Thompson JA. Peroxynitrite-mediated inactivation of manganese superoxide dismutase involves nitration and oxidation of critical tyrosine residues. Biochemistry 37: 1613-1622, 1998.
20. Marklund S and Marklund G. Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 47: 469-474, 1974.
21. Miles AM, Wink DA, Cook JC, and Grisham MB. Determination of nitric oxide using fluorescence spectroscopy. Methods Enzymol 268: 105-120, 1996.
22. Misko TP, Schilling RJ, Salvemini D, Moore WM, and Currie MG. A fluorometric assay for the measurement of nitrite in biological samples. Anal Biochem 214: 11-16, 1993.
23. Mohazzab KM, Kaminski PM, and Wolin MS. NADH oxidoreductase is a major source of superoxide anion in bovine coronary artery endothelium. Am J Physiol Heart Circ Physiol 266: H2568-H2572, 1994.
24. Moreau P, d'Uscio LV, and Luscher TF. Structure and reactivity of small arteries in aging. Cardiovasc Res 37: 247-253, 1998.
25. Muller-Delp JM, Spier SA, Ramsey MW, and Delp MD. Aging impairs endothelium-dependent vasodilation in rat skeletal muscle arterioles. Am J Physiol Heart Circ Physiol 283: H1662-H1672, 2002.
26. Oury TD, Day BJ, and Crapo JD. Extracellular superoxide dismutase in vessels and airways of humans and baboons. Free Radic Biol Med 20: 957-965, 1996.
27. Peng X, Haldar S, Deshpande S, Irani K, and Kass DA. Wall stiffness suppresses Akt/eNOS and cytoprotection in pulse-perfused endothelium. Hypertension 41: 378-381, 2003.
28. Qiu W, Kass DA, Hu Q, and Ziegelstein RC. Determinants of shear stress-stimulated endothelial nitric oxide production assessed in real-time by 4,5-diaminofluorescein fluorescence. Biochem Biophys Res Commun 286: 328-335, 2001.
29. Reckelhoff JF, Kellum JA, Blanchard EJ, Bacon EE, Wesley AJ, and Kruckeberg WC. Changes in nitric oxide precursor, 1-arginine, and metabolites, nitrate and nitrite, with aging. Life Sci 55: 1895-1902, 1994.
30. Rey FE, Li XC, Carretero OA, Garvin JL, and Pagano PJ. Perivascular superoxide anion contributes to impairment of endothelium-dependent relaxation: role of gp91(phox). Circulation 106: 2497-2502, 2002.
31. Sun D, Huang A, Koller A, and Kaley G. Decreased arteriolar sensitivity to shear stress in adult rats is reversed by chronic exercise activity. Microcirculation 9: 91-97, 2002.
32. Sun D, Messina EJ, Kaley G, and Koller A. Characteristics and origin of myogenic response in isolated mesenteric arterioles. Am J Physiol Heart Circ Physiol 263: H1486-H1491, 1992.
33. Taddei S, Virdis A, Ghiadoni L, Salvetti G, Bernini G, Magagna A, and Salvetti A. Age-related reduction of NO availability and oxidative stress in humans. Hypertension 38: 274-279, 2001.
34. Van der Loo B, Labugger R, Skepper JN, Bachschmid M, Kilo J, Powell JM, Palacios-Callender M, Erusalimsky JD, Quaschning T, Malinski T, Gygi D, Ullrich V, and Luscher TF. Enhanced peroxynitrite formation is associated with vascular aging. J Exp Med 192: 1731-1744, 2000.
35. Woodman CR, Price EM, and Laughlin MH. Aging induces muscle-specific impairment of endothelium-dependent dilation in skeletal muscle feed arteries. J Appl Physiol 93: 1685-1690, 2002.
36. Woodman CR, Price EM, and Laughlin MH. Selected Contribution: Aging impairs nitric oxide and prostacyclin mediation of endothelium-dependent dilation in soleus feed arteries. J Appl Physiol 95: 2164-2170, 2003.
37. Zou MH, Shi C, and Cohen RA. Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite. J Clin Invest 109: 817-826, 2002.