Pharmacological modulation of autophagy: Therapeutic potential and persisting obstacles

Nature Reviews Drug Discovery

Volumn 16, Issue 7, 2017, Pages 487-511

  Galluzzi, Lorenzo ^a,b   Bravo San Pedro, José Manuel ^b,c,d,e,f   Levine, Beth ^g,h   Green, Douglas R ⁱ   Kroemer, Guido ^{b,c,d,e,f,j,k}  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c SORBONNE UNIVERSITÉ   (France)

^d CENTRE DE RECHERCHE DES CORDELIERS   (France)

^e INSERM   (France)

^f INSTITUT GUSTAVE ROUSSY   (France)

^g UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^h HOWARD HUGHES MEDICAL INSTITUTE   (United States)

ⁱ ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^j KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^k HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 6,7 DIHYDRO 4 HYDROXY 3 (2' HYDROXY 1,1' BIPHENYL 4 YL) 6 OXOTHIENO[2,3 B]PYRIDINE 5 CARBONITRILE; ANTIMYCOBACTERIAL AGENT; AUTOPHAGY MODULATOR; BIOLOGICAL MARKER; BIOLOGICAL PRODUCT; BRD 5631; CARBAMAZEPINE; CARBON MONOXIDE; CHLORAMPHENICOL; EVEROLIMUS; GAMMA INTERFERON; HYDROGEN SULFIDE; HYDROXYCITRIC ACID; LITHIUM; LYS 05; MELATONIN; METFORMIN; MRT 67307; MRT 68921; NSC 185058; RAPAMYCIN; RESVERATROL; RETINOIC ACID; SAR 405; SBI 0206965; SIMVASTATIN; SPERMIDINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; WORTMANNIN;

ACUTE NEURONAL INJURY; AGING; ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; AUTOIMMUNE DISEASE; AUTOPHAGY; BACTERIAL INFECTION; BONE DISEASE; CALORIC RESTRICTION; CARDIOVASCULAR DISEASE; CEREBROVASCULAR ACCIDENT; CROHN DISEASE; DISEASE MARKER; DRUG EFFECT; DRUG TARGETING; EXERCISE; GENETIC MODEL; HUMAN; HUNTINGTON CHOREA; INFLAMMATION; INTOXICATION; KIDNEY DISEASE; LIVER DISEASE; LUNG DISEASE; LYSOSOMAL STORAGE DISORDER; MALIGNANT NEOPLASM; METABOLIC DISORDER; MULTIPLE SCLEROSIS; NERVE CELL LESION; NERVE DEGENERATION; NERVOUS SYSTEM INJURY; NEWBORN HYPOXIA; NONHUMAN; PARASITE; PARKINSONISM; PHARMACOLOGICAL MODULATION; PRIORITY JOURNAL; REVIEW; RHEUMATOID ARTHRITIS; SEIZURE; SYSTEMIC LUPUS ERYTHEMATOSUS; VIRUS INFECTION; VISUAL DISORDER; ANIMAL; DRUG DESIGN; DRUG EFFECTS; HEART DISEASES; MOLECULARLY TARGETED THERAPY; NEOPLASMS; NEURODEGENERATIVE DISEASES; PATHOLOGY; PATHOPHYSIOLOGY;

ANIMALS; AUTOPHAGY; DRUG DESIGN; HEART DISEASES; HUMANS; MOLECULAR TARGETED THERAPY; NEOPLASMS; NEURODEGENERATIVE DISEASES;

EID: 85019709546     PISSN: 14741776     EISSN: 14741784     Source Type: Journal    
DOI: 10.1038/nrd.2017.22     Document Type: Review

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