Stimulation of autophagy by rapamycin protects neurons from remote degeneration after acute focal brain damage

Autophagy

Volumn 8, Issue 2, 2012, Pages 222-235

  Viscomi, Maria Teresa ^a   D'Amelio, Marcello ^a,b   Cavallucci, Virve ^a   Latini, Laura ^a   Bisicchia, Elisa ^a,c   Nazio, Francesca ^d   Fanelli, Francesca ^e   Maccarrone, Mauro ^a,c   Moreno, Sandra ^a,c   Cecconi, Francesco ^a,d   Molinari, Marco ^a  

^a IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^b UNIVERSITY CAMPUS BIO MEDICO   (Italy)

^c UNIVERSITY OF TERAMO   (Italy)

^d UNIVERSITY OF ROME TOR VERGATA   (Italy)

^e ROMA TRE UNIVERSITY   (Italy)

Author keywords

Acute brain damage; Neurodegeneration; Neuronal death; Neuroprotection; Rapamycin

Indexed keywords

BECLIN 1; CASPASE 3; CHLOROQUINE; CYTOCHROME C; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MANGANESE SUPEROXIDE DISMUTASE; MICROTUBULE ASSOCIATED LIGHT CHAIN 3 II PROTEIN; MICROTUBULE ASSOCIATED LIGHT CHAIN 3 PROTEIN; PROTEIN; PROTEIN P62; RAPAMYCIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL SURVIVAL; CEREBELLECTOMY; CONTROLLED STUDY; CYTOSOL; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA FRAGMENTATION; ENZYME ACTIVATION; INFERIOR OLIVE; LYSOSOME; MALE; MOUSE; NERVE CELL DEGENERATION; NEUROPROTECTION; NONHUMAN; PONTINE NUCLEUS; TRANSGENIC MOUSE; UPREGULATION; WILD TYPE;

EID: 84857301687     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.8.2.18599     Document Type: Article

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