메뉴 건너뛰기




Volumn 30, Issue 37, 2010, Pages 12535-12544

Pathogenic lysosomal depletion in Parkinson's disease

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; RAPAMYCIN; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR; DOPAMINE; PEPTIDE HYDROLASE;

EID: 77956855813     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1920-10.2010     Document Type: Article
Times cited : (652)

References (52)
  • 1
    • 7444237665 scopus 로고    scopus 로고
    • Mutations in the glucocerebrosidase gene and Parkinson's disease in Ashkenazi Jews
    • Aharon-Peretz J, Rosenbaum H, Gershoni-Baruch R (2004) Mutations in the glucocerebrosidase gene and Parkinson's disease in Ashkenazi Jews. N Engl J Med 351:1972-1977.
    • (2004) N Engl J Med , vol.351 , pp. 1972-1977
    • Aharon-Peretz, J.1    Rosenbaum, H.2    Gershoni-Baruch, R.3
  • 3
    • 33748754701 scopus 로고    scopus 로고
    • Lysosome-associated membrane protein 1 (LAMP-1) in Alzheimer's disease
    • Barrachina M, Maes T, Buesa C, Ferrer I (2006) Lysosome-associated membrane protein 1 (LAMP-1) in Alzheimer's disease. Neuropathol Appl Neurobiol 32:505-516.
    • (2006) Neuropathol Appl Neurobiol , vol.32 , pp. 505-516
    • Barrachina, M.1    Maes, T.2    Buesa, C.3    Ferrer, I.4
  • 4
    • 54949137644 scopus 로고    scopus 로고
    • Lysosomal membrane permeabilization in cell death
    • Boya P, Kroemer G (2008) Lysosomal membrane permeabilization in cell death. Oncogene 27:6434-6451.
    • (2008) Oncogene , vol.27 , pp. 6434-6451
    • Boya, P.1    Kroemer, G.2
  • 7
    • 38349043984 scopus 로고    scopus 로고
    • Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species
    • Chen Y, McMillan-Ward E, Kong J, Israels SJ, Gibson SB (2007) Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species. J Cell Sci 120:4155-4166.
    • (2007) J Cell Sci , vol.120 , pp. 4155-4166
    • Chen, Y.1    McMillan-Ward, E.2    Kong, J.3    Israels, S.J.4    Gibson, S.B.5
  • 8
    • 35848947235 scopus 로고    scopus 로고
    • Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: Implications for neurodegeneration and cell death
    • Chu CT, Zhu J, Dagda R (2007) Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: implications for neurodegeneration and cell death. Autophagy 3:663-666.
    • (2007) Autophagy , vol.3 , pp. 663-666
    • Chu, C.T.1    Zhu, J.2    Dagda, R.3
  • 9
    • 68149123529 scopus 로고    scopus 로고
    • Alterations in lysosomal and proteasomal markers in Parkinson's disease: Relationship to alpha-synuclein inclusions
    • Chu Y, Dodiya H, Aebischer P, Olanow CW, Kordower JH (2009) Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions. Neurobiol Dis 35:385-398.
    • (2009) Neurobiol Dis , vol.35 , pp. 385-398
    • Chu, Y.1    Dodiya, H.2    Aebischer, P.3    Olanow, C.W.4    Kordower, J.H.5
  • 10
    • 4344659685 scopus 로고    scopus 로고
    • Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy
    • Cuervo AM, Stefanis L, Fredenburg R, Lansbury PT, Sulzer D (2004) Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy. Science 305:1292-1295.
    • (2004) Science , vol.305 , pp. 1292-1295
    • Cuervo, A.M.1    Stefanis, L.2    Fredenburg, R.3    Lansbury, P.T.4    Sulzer, D.5
  • 11
    • 50249168137 scopus 로고    scopus 로고
    • Mitochondrially localized ERK2 regulates mitophagy and autophagic cell stress: Implications for Parkinson's disease
    • Dagda RK, Zhu J, Kulich SM, Chu CT (2008) Mitochondrially localized ERK2 regulates mitophagy and autophagic cell stress: implications for Parkinson's disease. Autophagy 4:770-782.
    • (2008) Autophagy , vol.4 , pp. 770-782
    • Dagda, R.K.1    Zhu, J.2    Kulich, S.M.3    Chu, C.T.4
  • 12
    • 0141741347 scopus 로고    scopus 로고
    • Parkinson's disease: Mechanisms and models
    • Dauer W, Przedborski S (2003) Parkinson's disease: mechanisms and models. Neuron 39:889-909.
    • (2003) Neuron , vol.39 , pp. 889-909
    • Dauer, W.1    Przedborski, S.2
  • 15
    • 0033811707 scopus 로고    scopus 로고
    • The organic cation transporter OCT2 mediates the uptake of beta-adrenoceptor antagonists across the apical membrane of renal LLC-PK(1) cell monolayers
    • Dudley AJ, Bleasby K, Brown CD (2000) The organic cation transporter OCT2 mediates the uptake of beta-adrenoceptor antagonists across the apical membrane of renal LLC-PK(1) cell monolayers. Br J Pharmacol 131:71-79.
    • (2000) Br J Pharmacol , vol.131 , pp. 71-79
    • Dudley, A.J.1    Bleasby, K.2    Brown, C.D.3
  • 16
    • 0017288256 scopus 로고
    • Ultrastructure of Lewy bodies in the stellate ganglion
    • Forno LS, Norville RL (1976) Ultrastructure of Lewy bodies in the stellate ganglion. Acta Neuropathol 34:183-197.
    • (1976) Acta Neuropathol , vol.34 , pp. 183-197
    • Forno, L.S.1    Norville, R.L.2
  • 17
    • 77952007543 scopus 로고    scopus 로고
    • Mammalian target of rapamycin (mTOR): Conducting the cellular signaling symphony
    • Foster KG, Fingar DC (2010) Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony. J Biol Chem 285:14071-14077.
    • (2010) J Biol Chem , vol.285 , pp. 14071-14077
    • Foster, K.G.1    Fingar, D.C.2
  • 20
    • 72649106290 scopus 로고    scopus 로고
    • Phosphorus and proton magnetic resonance spectroscopy demonstrates mitochondrial dysfunction in early and advanced Parkinson's disease
    • Hattingen E, Magerkurth J, Pilatus U, Mozer A, Seifried C, Steinmetz H, Zanella F, Hilker R (2009) Phosphorus and proton magnetic resonance spectroscopy demonstrates mitochondrial dysfunction in early and advanced Parkinson's disease. Brain 132:3285-3297.
    • (2009) Brain , vol.132 , pp. 3285-3297
    • Hattingen, E.1    Magerkurth, J.2    Pilatus, U.3    Mozer, A.4    Seifried, C.5    Steinmetz, H.6    Zanella, F.7    Hilker, R.8
  • 21
    • 0347986548 scopus 로고    scopus 로고
    • Sucrose-induced vacuolation results in increased expression of cholesterol biosynthesis and lysosomal genes
    • Helip-Wooley A, Thoene JG (2004) Sucrose-induced vacuolation results in increased expression of cholesterol biosynthesis and lysosomal genes. Exp Cell Res 292:89-100.
    • (2004) Exp Cell Res , vol.292 , pp. 89-100
    • Helip-Wooley, A.1    Thoene, J.G.2
  • 24
    • 34548077575 scopus 로고    scopus 로고
    • Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3
    • Kimura S, Noda T, Yoshimori T (2007) Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3. Autophagy 3:452-460.
    • (2007) Autophagy , vol.3 , pp. 452-460
    • Kimura, S.1    Noda, T.2    Yoshimori, T.3
  • 26
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine B, Kroemer G (2008) Autophagy in the pathogenesis of disease. Cell 132:27-42.
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 28
    • 75749127850 scopus 로고    scopus 로고
    • Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease
    • Malagelada C, Jin ZH, Jackson-Lewis V, Przedborski S, Greene LA (2010) Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. J Neurosci 30:1166-1175.
    • (2010) J Neurosci , vol.30 , pp. 1166-1175
    • Malagelada, C.1    Jin, Z.H.2    Jackson-Lewis, V.3    Przedborski, S.4    Greene, L.A.5
  • 31
    • 36249025723 scopus 로고    scopus 로고
    • Autophagy: Process and function
    • Mizushima N (2007) Autophagy: process and function. Genes Dev 21: 2861-2873.
    • (2007) Genes Dev , vol.21 , pp. 2861-2873
    • Mizushima, N.1
  • 32
    • 35848967804 scopus 로고    scopus 로고
    • How to interpret LC3 immunoblotting
    • Mizushima N, Yoshimori T (2007) How to interpret LC3 immunoblotting. Autophagy 3:542-545.
    • (2007) Autophagy , vol.3 , pp. 542-545
    • Mizushima, N.1    Yoshimori, T.2
  • 33
    • 58149314211 scopus 로고    scopus 로고
    • Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
    • Narendra D, Tanaka A, Suen DF, Youle RJ (2008) Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol 183:795-803.
    • (2008) J Cell Biol , vol.183 , pp. 795-803
    • Narendra, D.1    Tanaka, A.2    Suen, D.F.3    Youle, R.J.4
  • 39
    • 34247161367 scopus 로고    scopus 로고
    • Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein
    • Sarkar S, Davies JE, Huang Z, Tunnacliffe A, Rubinsztein DC (2007) Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein. J Biol Chem 282:5641-5652.
    • (2007) J Biol Chem , vol.282 , pp. 5641-5652
    • Sarkar, S.1    Davies, J.E.2    Huang, Z.3    Tunnacliffe, A.4    Rubinsztein, D.C.5
  • 40
    • 57649227693 scopus 로고    scopus 로고
    • Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies
    • Sarkar S, Ravikumar B, Floto RA, Rubinsztein DC (2009) Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine- expanded huntingtin and related proteinopathies. Cell Death Differ 16:46-56.
    • (2009) Cell Death Differ , vol.16 , pp. 46-56
    • Sarkar, S.1    Ravikumar, B.2    Floto, R.A.3    Rubinsztein, D.C.4
  • 41
    • 34848920863 scopus 로고    scopus 로고
    • ROS, mitochondria and the regulation of autophagy
    • Scherz-Shouval R, Elazar Z (2007) ROS, mitochondria and the regulation of autophagy. Trends Cell Biol 17:422-427.
    • (2007) Trends Cell Biol , vol.17 , pp. 422-427
    • Scherz-Shouval, R.1    Elazar, Z.2
  • 43
    • 45449093259 scopus 로고    scopus 로고
    • Neuronal pigmented autophagic vacuoles: Lipofuscin, neuromelanin, and ceroid as macroautophagic responses during aging and disease
    • Sulzer D, Mosharov E, Talloczy Z, Zucca FA, Simon JD, Zecca L (2008) Neuronal pigmented autophagic vacuoles: lipofuscin, neuromelanin, and ceroid as macroautophagic responses during aging and disease. J Neurochem 106:24-36.
    • (2008) J Neurochem , vol.106 , pp. 24-36
    • Sulzer, D.1    Mosharov, E.2    Talloczy, Z.3    Zucca, F.A.4    Simon, J.D.5    Zecca, L.6
  • 45
    • 33744937070 scopus 로고    scopus 로고
    • Subcellular proteomics reveals neuromelanin granules to be a lysosome-related organelle
    • Tribl F, Marcus K, Meyer HE, Bringmann G, Gerlach M, Riederer P (2006) Subcellular proteomics reveals neuromelanin granules to be a lysosome-related organelle. J Neural Transm 113:741-749.
    • (2006) J Neural Transm , vol.113 , pp. 741-749
    • Tribl, F.1    Marcus, K.2    Meyer, H.E.3    Bringmann, G.4    Gerlach, M.5    Riederer, P.6
  • 46
    • 0038205745 scopus 로고    scopus 로고
    • Neurological diseases: Targeting programmed cell death in neurodegenerative diseases
    • Vila M, Przedborski S (2003) Neurological diseases: Targeting programmed cell death in neurodegenerative diseases. Nat Rev Neurosci 4:365-375.
    • (2003) Nat Rev Neurosci , vol.4 , pp. 365-375
    • Vila, M.1    Przedborski, S.2
  • 48
    • 53149087460 scopus 로고    scopus 로고
    • Mitochondrial alterations in Parkinson's disease: New clues
    • Vila M, Ramonet D, Perier C (2008) Mitochondrial alterations in Parkinson's disease: new clues. J Neurochem 107:317-328.
    • (2008) J Neurochem , vol.107 , pp. 317-328
    • Vila, M.1    Ramonet, D.2    Perier, C.3
  • 50
    • 53049098471 scopus 로고    scopus 로고
    • Wild type alphasynuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells
    • Vogiatzi T, Xilouri M, Vekrellis K, Stefanis L (2008) Wild type alphasynuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells. J Biol Chem 283:23542-23556.
    • (2008) J Biol Chem , vol.283 , pp. 23542-23556
    • Vogiatzi, T.1    Xilouri, M.2    Vekrellis, K.3    Stefanis, L.4
  • 51
    • 68449089023 scopus 로고    scopus 로고
    • Metabolic activity determines efficacy of macroautophagic clearance of pathological oligomeric alpha-synuclein
    • Yu WH, Dorado B, Figueroa HY, Wang L, Planel E, Cookson MR, Clark LN, Duff KE (2009) Metabolic activity determines efficacy of macroautophagic clearance of pathological oligomeric alpha-synuclein. Am J Pathol 175:736-747.
    • (2009) Am J Pathol , vol.175 , pp. 736-747
    • Yu, W.H.1    Dorado, B.2    Figueroa, H.Y.3    Wang, L.4    Planel, E.5    Cookson, M.R.6    Clark, L.N.7    Duff, K.E.8
  • 52
    • 33847048316 scopus 로고    scopus 로고
    • Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death
    • Zhu JH, Horbinski C, Guo F, Watkins S, Uchiyama Y, Chu CT (2007) Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death. Am J Pathol 170:75-86.
    • (2007) Am J Pathol , vol.170 , pp. 75-86
    • Zhu, J.H.1    Horbinski, C.2    Guo, F.3    Watkins, S.4    Uchiyama, Y.5    Chu, C.T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.