HSV-1 ICP34.5 Confers Neurovirulence by Targeting the Beclin 1 Autophagy Protein

Cell Host and Microbe

Volumn 1, Issue 1, 2007, Pages 23-35

  Orvedahl, Anthony ^a   Alexander, Diane ^c   Tallóczy, Zsolt ^d   Sun, Qihua ^a   Wei, Yongjie ^a   Zhang, Wei ^b   Burns, Dennis ^a   Leib, David A ^c   Levine, Beth ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NONE   (United States)

Author keywords

MICROBIO

Indexed keywords

AMINO ACID; BECLIN1 PROTEIN; CELL PROTEIN; ICP34.5 PROTEIN; INITIATION FACTOR 2ALPHA; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; FATALITY; FEMALE; HERPES SIMPLEX VIRUS 1; HOST RESISTANCE; HUMAN; HUMAN CELL; INNATE IMMUNITY; MALE; MOLECULAR DYNAMICS; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; VIROGENESIS; VIRUS CELL INTERACTION; VIRUS ENCEPHALITIS; VIRUS IMMUNITY; VIRUS MUTANT; VIRUS PATHOGENESIS; VIRUS VIRULENCE;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CELL LINE; CEREBRAL CORTEX; EIF-2 KINASE; HUMANS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; PHAGOSOMES; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; SURVIVAL RATE; TWO-HYBRID SYSTEM TECHNIQUES; VIRAL PROTEINS;

HUMAN HERPESVIRUS 1; MAMMALIA; MUS;

EID: 33947715151     PISSN: 19313128     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chom.2006.12.001     Document Type: Article

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