Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy

Nature Medicine

Volumn 19, Issue 3, 2013, Pages 351-357

  Papadakis, Michalis ^a   Hadley, Gina ^a   Xilouri, Maria ^b   Hoyte, Lisa C ^a   Nagel, Simon ^a,c   Mcmenamin, M Mary ^a   Tsaknakis, Grigorios ^d,e   Watt, Suzanne M ^d,e   Drakesmith, Cynthia Wright ^f   Chen, Ruoli ^a,g   Wood, Matthew J A ^a   Zhao, Zonghang ^h   Kessler, Benedikt ^f   Vekrellis, Kostas ^b   Buchan, Alastair M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b BIOMEDICAL RESEARCH FOUNDATION   (Greece)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d NHS BLOOD AND TRANSPLANT   (United Kingdom)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f UNIVERSITY OF OXFORD   (United Kingdom)

^g KEELE UNIVERSITY   (United Kingdom)

^h UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HAMARTIN; OXYGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; BRAIN ISCHEMIA; CELL DEATH; CONTROLLED STUDY; HABITUATION; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; ISCHEMIC PRECONDITIONING; LOCOMOTION; NERVE CELL; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; TASK PERFORMANCE; TUBEROUS SCLEROSIS; UPREGULATION;

ADENINE; ANIMALS; ANOXIA; AUTOPHAGY; CA1 REGION, HIPPOCAMPAL; CA3 REGION, HIPPOCAMPAL; CELLS, CULTURED; HYPOXIA-ISCHEMIA, BRAIN; ISCHEMIC PRECONDITIONING; MALE; NEUROPROTECTIVE AGENTS; PROSENCEPHALON; PROTEINS; RATS; RATS, WISTAR; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIROLIMUS; TUMOR SUPPRESSOR PROTEINS;

EID: 84875232070     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3097     Document Type: Article

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