Impaired autophagy in macrophages promotes inflammatory eye disease

Autophagy

Volumn 12, Issue 10, 2016, Pages 1876-1885

  Santeford, Andrea ^a   Wiley, Luke A ^b   Park, Sunmin ^a   Bamba, Sonya ^a   Nakamura, Rei ^a   Gdoura, Abdelaziz ^a   Ferguson, Thomas A ^a   Rao, P Kumar ^a   Guan, Jun Lin ^c   Saitoh, Tatsuya ^d   Akira, Shizuo ^e   Xavier, Ramnik ^f,g   Virgin, Herbert W ^a   Apte, Rajendra S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF TOKUSHIMA   (Japan)

^e OSAKA UNIVERSITY   (Japan)

^f BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^g HARVARD MEDICAL SCHOOL   (United States)

Author keywords

autophagy; eye; inflammasome; innate immunity; macrophage; uveitis

Indexed keywords

CASPASE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; INFLAMMASOME; INTERLEUKIN 1BETA; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; ATG16L1 PROTEIN, HUMAN; ATG5 PROTEIN, MOUSE; AUTOPHAGY RELATED PROTEIN; AUTOPHAGY RELATED PROTEIN 5; CYTOKINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNE UVEITIS; AUTOPHAGY; BLINDNESS; CONTROLLED STUDY; CROHN DISEASE; CYTOKINE RELEASE; DISEASE ASSOCIATION; DISEASE SEVERITY; ENDOTOXIN-INDUCED UVEITIS; ENZYME ACTIVITY; EYE DISEASE; GENE DELETION; GENE LOSS; HISTOPATHOLOGY; HOMEOSTASIS; HUMAN; INFLAMMATION; MEDIATOR; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PHENOTYPE; SYSTEMIC DISEASE; ANIMAL; COMPLICATION; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; MACROPHAGE; METABOLISM; PATHOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM; ULTRASTRUCTURE; UVEITIS;

ANIMALS; AUTOPHAGY; AUTOPHAGY-RELATED PROTEIN 5; AUTOPHAGY-RELATED PROTEINS; CYTOKINES; EYE DISEASES; GENE DELETION; GENE EXPRESSION REGULATION; HUMANS; INFLAMMASOMES; INFLAMMATION; INTERLEUKIN-1BETA; MACROPHAGES; MICE, KNOCKOUT; POLYMORPHISM, SINGLE NUCLEOTIDE; UVEITIS;

EID: 84982295433     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.1080/15548627.2016.1207857     Document Type: Article

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