Loss of Autophagy Diminishes Pancreatic β Cell Mass and Function with Resultant Hyperglycemia

Cell Metabolism

Volumn 8, Issue 4, 2008, Pages 318-324

  Jung, Hye Seung ^a   Chung, Kun Wook ^a   Won Kim, Jeong ^a   Kim, Jin ^b   Komatsu, Masaaki ^c,d,e   Tanaka, Keiji ^c   Nguyen, Yen Hoang ^a   Kang, Tong Mook ^a   Yoon, Kun Ho ^f   Kim, Ji Won ^f   Jeong, Yeon Taek ^a   Han, Myoung Sook ^a   Lee, Moon Kyu ^a   Kim, Kwang Won ^a   Shin, Jaekyoon ^a   Lee, Myung Shik ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b The Catholic University of Korea College of Medicine   (South Korea)

^c TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^d JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^f The Catholic University of Korea   (South Korea)

Author keywords

HUMDISEASE; PROTEINS

Indexed keywords

ATG7 PROTEIN; CALCIUM ION; CYTOPLASM PROTEIN; INSULIN; PROTEIN P62; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CALCIUM CELL LEVEL; CELL PROLIFERATION; CELL STRUCTURE; CELL VACUOLE; CONTROLLED STUDY; DIABETES MELLITUS; ENDOPLASMIC RETICULUM; GLUCOSE HOMEOSTASIS; HYPERGLYCEMIA; IMPAIRED GLUCOSE TOLERANCE; INSULIN BLOOD LEVEL; INSULIN DEFICIENCY; INSULIN RELEASE; MITOCHONDRION SWELLING; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN LOCALIZATION;

ANIMALS; AUTOPHAGY; DIABETES MELLITUS, TYPE 2; GLUCOSE; HYPERGLYCEMIA; INSULIN; INSULIN-SECRETING CELLS; MICE; MICE, KNOCKOUT; MICROTUBULE-ASSOCIATED PROTEINS; UBIQUITIN;

MUS;

EID: 52749094770     PISSN: 15504131     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cmet.2008.08.013     Document Type: Article

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