메뉴 건너뛰기




Volumn 5, Issue , 2014, Pages

A dual role for autophagy in a murine model of lung cancer

(25)  Rao, Shuan a   Tortola, Luigi a   Perlot, Thomas a   Wirnsberger, Gerald a   Novatchkova, Maria a   Nitsch, Roberto a   Sykacek, Peter b   Frank, Lukas c   Schramek, Daniel a   Komnenovic, Vukoslav a   Sigl, Verena a   Aumayr, Karin a   Schmauss, Gerald a   Fellner, Nicole d   Handschuh, Stephan e   Glösmann, Martin e   Pasierbek, Pawel a   Schlederer, Michaela c,f   Resch, Guenter P d   Ma, Yuting g,h,i   more..


Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; ATG5 PROTEIN, MOUSE; MICROTUBULE ASSOCIATED PROTEIN;

EID: 84892882660     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4056     Document Type: Article
Times cited : (359)

References (54)
  • 1
    • 81055144784 scopus 로고    scopus 로고
    • Autophagy: Renovation of cells and tissues
    • Mizushima, N. & Komatsu, M. Autophagy: Renovation of cells and tissues. Cell 147, 728-741 (2011
    • (2011) Cell , vol.147 , pp. 728-741
    • Mizushima, N.1    Komatsu, M.2
  • 2
    • 0023065242 scopus 로고    scopus 로고
    • Intracellular protein catabolism and its control during nutrient deprivation and supply
    • Mortimore, G. & Poso, A. Intracellular protein catabolism and its control during nutrient deprivation and supply. Annu. Rev. Nutr. 7, 539-564 (2002
    • (2002) Annu. Rev. Nutr , vol.7 , pp. 539-564
    • Mortimore, G.1    Poso, A.2
  • 3
    • 0034537290 scopus 로고    scopus 로고
    • Autophagy as a regulated pathway of cellular degradation
    • DOI 10.1126/science.290.5497.1717
    • Klionsky, D. J. Autophagy as a regulated pathway of cellular degradation. Science 290, 1717-1721 (2000 (Pubitemid 32004796)
    • (2000) Science , vol.290 , Issue.5497 , pp. 1717-1721
    • Klionsky, D.J.1    Emr, S.D.2
  • 4
    • 33745192802 scopus 로고    scopus 로고
    • Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
    • Hara, T. et al. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 441, 885-889 (2006
    • (2006) Nature , vol.441 , pp. 885-889
    • Hara, T.1
  • 7
    • 79251592842 scopus 로고    scopus 로고
    • Why starving cells eat themselves
    • Hardie, D. G. Why starving cells eat themselves. Science 331, 410-411 (2011
    • (2011) Science , vol.331 , pp. 410-411
    • Hardie, D.G.1
  • 8
    • 57649184088 scopus 로고    scopus 로고
    • Control of autophagy by oncogenes and tumor suppressor genes
    • Maiuri, M. C. et al. Control of autophagy by oncogenes and tumor suppressor genes. Cell Death Differ. 16, 87-93 (2008
    • (2008) Cell Death Differ , vol.16 , pp. 87-93
    • Maiuri, M.C.1
  • 11
    • 84855712059 scopus 로고    scopus 로고
    • Autophagic removal of micronuclei
    • Rello-Varona, S. et al. Autophagic removal of micronuclei. Cell Cycle 11, 170-176 (2012
    • (2012) Cell Cycle , vol.11 , pp. 170-176
    • Rello-Varona, S.1
  • 12
    • 80053564250 scopus 로고    scopus 로고
    • Ncb2332
    • Kuo, T-C. et al. ncb2332. Nature 13, 1214-1223 (2011
    • (2011) Nature , vol.13 , pp. 1214-1223
    • Kuo, T.-C.1
  • 13
    • 84880585547 scopus 로고    scopus 로고
    • Lysosome-mediated processing of chromatin in senescence
    • Ivanov, A. et al. Lysosome-mediated processing of chromatin in senescence. J. Cell Biol. 202, 129-143 (2013
    • (2013) J. Cell Biol , vol.202 , pp. 129-143
    • Ivanov, A.1
  • 14
    • 84885574879 scopus 로고    scopus 로고
    • Prolonged autophagy by MTOR inhibitor leads radioresistant cancer cells into senescence
    • Nam, H. Y., Han, M. W., Chang, H. W., Kim, S. Y. & Kim, S. W. Prolonged autophagy by MTOR inhibitor leads radioresistant cancer cells into senescence. Autophagy 9, 1-2 (2013
    • (2013) Autophagy , vol.9 , pp. 1-2
    • Nam, H.Y.1    Han, M.W.2    Chang, H.W.3    Kim, S.Y.4    Kim, S.W.5
  • 16
    • 84861526009 scopus 로고    scopus 로고
    • Deconvoluting the context-dependent role for autophagy in cancer
    • White, E. Deconvoluting the context-dependent role for autophagy in cancer. Nat. Rev. Cancer 12, 401-410 (2012
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 401-410
    • White, E.1
  • 17
    • 84865191462 scopus 로고    scopus 로고
    • Autophagic activity dictates the cellular response to oncogenic RAS
    • Wang, Y., Wang, X. D., Lapi, E. & Sullivan, A. Autophagic activity dictates the cellular response to oncogenic RAS. PNAS 109, 13325-13330 (2012
    • (2012) PNAS , vol.109 , pp. 13325-13330
    • Wang, Y.1    Wang, X.D.2    Lapi, E.3    Sullivan, A.4
  • 18
    • 79952228407 scopus 로고    scopus 로고
    • Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
    • Guo, J. Y. et al. Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. Genes Dev. 25, 460-470 (2011
    • (2011) Genes Dev , vol.25 , pp. 460-470
    • Guo, J.Y.1
  • 19
    • 78751511180 scopus 로고    scopus 로고
    • Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation
    • Lock, R. et al. Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation. Mol. Biol. Cell 22, 165-178 (2011
    • (2011) Mol. Biol. Cell , vol.22 , pp. 165-178
    • Lock, R.1
  • 20
    • 70849093011 scopus 로고    scopus 로고
    • The Rac1/MKK7/JNK pathway signals upregulation of Atg5 and subsequent autophagic cell death in response to oncogenic Ras
    • Byun, J. Y. et al. The Rac1/MKK7/JNK pathway signals upregulation of Atg5 and subsequent autophagic cell death in response to oncogenic Ras. Carcinogenesis 30, 1880-1888 (2009
    • (2009) Carcinogenesis , vol.30 , pp. 1880-1888
    • Byun, J.Y.1
  • 21
    • 79953306808 scopus 로고    scopus 로고
    • Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival
    • Elgendy, M., Sheridan, C., Brumatti, G. & Martin, S. J. Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival. Mol. Cell 42, 23-35 (2011
    • (2011) Mol. Cell , vol.42 , pp. 23-35
    • Elgendy, M.1    Sheridan, C.2    Brumatti, G.3    Martin, S.J.4
  • 22
    • 84892853222 scopus 로고    scopus 로고
    • Ras inhibition enhances autophagy, which partially protects cells from death
    • Schmukler, E. et al. Ras inhibition enhances autophagy, which partially protects cells from death. Oncotarget 4, 142-152 (2012
    • (2012) Oncotarget , vol.4 , pp. 142-152
    • Schmukler, E.1
  • 25
    • 84867031825 scopus 로고    scopus 로고
    • Down-regulated expression of ATG5 in colorectal cancer
    • Cho, D. H., Jo, Y. K., Kim, S. C., Park, I. J. & Kim, J. C. Down-regulated expression of ATG5 in colorectal cancer. Anticancer Res. 32, 4091-4096 (2012
    • (2012) Anticancer Res , vol.32 , pp. 4091-4096
    • Cho, D.H.1    Jo, Y.K.2    Kim, S.C.3    Park, I.J.4    Kim, J.C.5
  • 26
    • 84884693919 scopus 로고    scopus 로고
    • Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma
    • 202ra123
    • Liu, H. et al. Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma. Sci. Transl. Med. 5, 202ra123 (2013
    • (2013) Sci. Transl. Med , vol.5
    • Liu, H.1
  • 29
    • 79952123700 scopus 로고    scopus 로고
    • The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression
    • Schramek, D. et al. The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression. Nat. Genet. 43, 212-219 (2011
    • (2011) Nat. Genet , vol.43 , pp. 212-219
    • Schramek, D.1
  • 31
    • 78650906609 scopus 로고    scopus 로고
    • Regulation of E2Fs and senescence by PML nuclear bodies
    • Vernier, M. et al. Regulation of E2Fs and senescence by PML nuclear bodies. Genes Dev. 25, 41-50 (2011
    • (2011) Genes Dev , vol.25 , pp. 41-50
    • Vernier, M.1
  • 33
    • 17744406409 scopus 로고    scopus 로고
    • Epithelial-neutrophil activating peptide (ENA-78) is an important angiogenic factor in non-small cell lung cancer
    • Arenberg, D. A. D. et al. Epithelial-neutrophil activating peptide (ENA-78) is an important angiogenic factor in non-small cell lung cancer. J. Clin. Invest. 102, 465-472 (1998
    • (1998) J. Clin. Invest , vol.102 , pp. 465-472
    • Arenberg, D.A.D.1
  • 34
    • 70350504453 scopus 로고    scopus 로고
    • The DNA-damage response in human biology and disease
    • Jackson, S. P. & Bartek, J. The DNA-damage response in human biology and disease. Nature 461, 1071-1078 (2009
    • (2009) Nature , vol.461 , pp. 1071-1078
    • Jackson, S.P.1    Bartek, J.2
  • 36
    • 79953151458 scopus 로고    scopus 로고
    • Cancer immunoediting: Integrating immunity's roles in cancer suppression and promotion
    • Schreiber, R. D., Old, L. J. & Smyth, M. J. Cancer immunoediting: Integrating immunity's roles in cancer suppression and promotion. Science 331, 1565-1570 (2011
    • (2011) Science , vol.331 , pp. 1565-1570
    • Schreiber, R.D.1    Old, L.J.2    Smyth, M.J.3
  • 37
    • 78751672975 scopus 로고    scopus 로고
    • Autophagy in immunity and inflammation
    • Levine, B., Mizushima, N. & Virgin, H. W. Autophagy in immunity and inflammation. Nature 469, 323-335 (2011
    • (2011) Nature , vol.469 , pp. 323-335
    • Levine, B.1    Mizushima, N.2    Virgin, H.W.3
  • 38
    • 79951910694 scopus 로고    scopus 로고
    • Autophagy in immunity and cell-Autonomous defense against intracellular microbes
    • Deretic, V. Autophagy in immunity and cell-Autonomous defense against intracellular microbes. Immunol. Rev. 240, 92-104 (2011
    • (2011) Immunol. Rev , vol.240 , pp. 92-104
    • Deretic, V.1
  • 39
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • DOI 10.1126/science.1079490
    • Hori, S. Control of regulatory T cell development by the transcription factor Foxp3. Science 299, 1057-1061 (2003 (Pubitemid 36222930)
    • (2003) Science , vol.299 , Issue.5609 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 41
    • 43949105866 scopus 로고    scopus 로고
    • Regulatory T cells and immune tolerance
    • DOI 10.1016/j.cell.2008.05.009, PII S0092867408006247
    • Sakaguchi, S., Yamaguchi, T., Nomura, T. & Ono, M. Regulatory T cells and immune tolerance. Cell 133, 775-787 (2008 (Pubitemid 351707693)
    • (2008) Cell , vol.133 , Issue.5 , pp. 775-787
    • Sakaguchi, S.1    Yamaguchi, T.2    Nomura, T.3    Ono, M.4
  • 42
    • 34447643405 scopus 로고    scopus 로고
    • Control of immune responses by antigen-specific regulatory t cells expressing the folate receptor
    • DOI 10.1016/j.immuni.2007.04.017, PII S1074761307003263
    • Yamaguchi, T. et al. Control of immune responses by antigen-specific regulatory T cells expressing the folate receptor. Immunity 27, 145-159 (2007 (Pubitemid 47089022)
    • (2007) Immunity , vol.27 , Issue.1 , pp. 145-159
    • Yamaguchi, T.1    Hirota, K.2    Nagahama, K.3    Ohkawa, K.4    Takahashi, T.5    Nomura, T.6    Sakaguchi, S.7
  • 43
    • 77950794689 scopus 로고    scopus 로고
    • Multiple antitumor mechanisms downstream of prophylactic regulatory T-cell depletion
    • Teng, M. W. L. et al. Multiple antitumor mechanisms downstream of prophylactic regulatory T-cell depletion. Cancer Res. 70, 2665-2674 (2010
    • (2010) Cancer Res , vol.70 , pp. 2665-2674
    • Teng, M.W.L.1
  • 44
    • 85047685683 scopus 로고    scopus 로고
    • Ecto-50-nucleotidase (CD73) regulation by hypoxiainducible factor-1 mediates permeability changes in intestinal epithelia
    • Synnestvedt, K. et al. Ecto-50-nucleotidase (CD73) regulation by hypoxiainducible factor-1 mediates permeability changes in intestinal epithelia. J. Clin. Invest. 110, 993-1002 (2002
    • (2002) J. Clin. Invest , vol.110 , pp. 993-1002
    • Synnestvedt, K.1
  • 45
    • 77957564570 scopus 로고    scopus 로고
    • Extracellular adenosine triphosphate and adenosine in cancer
    • Stagg, J. & Smyth, M. J. Extracellular adenosine triphosphate and adenosine in cancer. Oncogene 29, 5346-5358 (2010
    • (2010) Oncogene , vol.29 , pp. 5346-5358
    • Stagg, J.1    Smyth, M.J.2
  • 46
    • 77956134431 scopus 로고    scopus 로고
    • CD39/ENTPD1 expression by CD4Foxp3 regulatory T cells promotes hepatic metastatic tumor growth in mice
    • Sun, X. et al. CD39/ENTPD1 expression by CD4Foxp3 regulatory T cells promotes hepatic metastatic tumor growth in mice. YGAST 139, 1030-1040 (2010
    • (2010) YGAST , vol.139 , pp. 1030-1040
    • Sun, X.1
  • 48
    • 66449099090 scopus 로고    scopus 로고
    • Autophagy suppresses tumorigenesis through elimination of p62
    • Mathew, R. et al. Autophagy suppresses tumorigenesis through elimination of p62. Cell 137, 1062-1075 (2009
    • (2009) Cell , vol.137 , pp. 1062-1075
    • Mathew, R.1
  • 49
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine, B. & Kroemer, G. Autophagy in the pathogenesis of disease. Cell 132, 27-42 (2008
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 50
    • 84879777723 scopus 로고    scopus 로고
    • Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
    • Guo, J. Y. et al. Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis. Genes Dev. 27, 1447-1461 (2013
    • (2013) Genes Dev , vol.27 , pp. 1447-1461
    • Guo, J.Y.1
  • 52
    • 79952613153 scopus 로고    scopus 로고
    • Mesodermal developmental gene Tbx15 impairs adipocyte differentiation and mitochondrial respiration
    • Gesta, S. et al. Mesodermal developmental gene Tbx15 impairs adipocyte differentiation and mitochondrial respiration. PNAS 108, 2771-2776 (2011
    • (2011) PNAS , vol.108 , pp. 2771-2776
    • Gesta, S.1
  • 53
    • 79952122321 scopus 로고    scopus 로고
    • Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism
    • Ren, D. et al. Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism. PNAS 108, 1433-1438 (2011
    • (2011) PNAS , vol.108 , pp. 1433-1438
    • Ren, D.1
  • 54
    • 61649124483 scopus 로고    scopus 로고
    • MicroCT for developmental biology: A versatile tool for high-contrast 3D imaging at histological resolutions
    • Metscher, B. D. MicroCT for developmental biology: A versatile tool for high-contrast 3D imaging at histological resolutions. Dev. Dyn 238, 632-640 (2009
    • (2009) Dev. Dyn , vol.238 , pp. 632-640
    • Metscher, B.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.