메뉴 건너뛰기




Volumn 58, Issue 5, 2013, Pages 993-999

Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice

Author keywords

Alcohol; Carbamazepine; Hepatic steatosis; High fat diet; Macroautophagy

Indexed keywords

ALCOHOL; CARBAMAZEPINE; CHLOROQUINE; GLUCOSE; INSULIN; LIVER ENZYME; RAPAMYCIN; TRIACYLGLYCEROL;

EID: 84876287362     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2013.01.011     Document Type: Article
Times cited : (366)

References (32)
  • 1
    • 37749053679 scopus 로고    scopus 로고
    • Determinants of alcohol use and abuse: Impact of quantity and frequency patterns on liver disease
    • S. Zakhari, and T.K. Li Determinants of alcohol use and abuse: impact of quantity and frequency patterns on liver disease Hepatology 46 2007 2032 2039
    • (2007) Hepatology , vol.46 , pp. 2032-2039
    • Zakhari, S.1    Li, T.K.2
  • 2
    • 12844288099 scopus 로고    scopus 로고
    • Alcoholic fatty liver: Its pathogenesis and mechanism of progression to inflammation and fibrosis
    • C.S. Lieber Alcoholic fatty liver: its pathogenesis and mechanism of progression to inflammation and fibrosis Alcohol 34 2004 9 19
    • (2004) Alcohol , vol.34 , pp. 9-19
    • Lieber, C.S.1
  • 4
    • 0028677870 scopus 로고
    • Pathological spectrum of alcoholic liver disease
    • P.D. Hall Pathological spectrum of alcoholic liver disease Alcohol Alcohol Suppl 2 1994 303 313
    • (1994) Alcohol Alcohol Suppl , vol.2 , pp. 303-313
    • Hall, P.D.1
  • 5
    • 0037129380 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease
    • P. Angulo Nonalcoholic fatty liver disease N Engl J Med 346 2002 1221 1231
    • (2002) N Engl J Med , vol.346 , pp. 1221-1231
    • Angulo, P.1
  • 6
    • 75449094816 scopus 로고    scopus 로고
    • Obesity and nonalcoholic fatty liver disease: Biochemical, metabolic, and clinical implications
    • E. Fabbrini, S. Sullivan, and S. Klein Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications Hepatology 51 2009 679 689
    • (2009) Hepatology , vol.51 , pp. 679-689
    • Fabbrini, E.1    Sullivan, S.2    Klein, S.3
  • 7
    • 4344628553 scopus 로고    scopus 로고
    • Insulin resistance and the pathogenesis of nonalcoholic fatty liver disease
    • J. Choudhury, and A.J. Sanyal Insulin resistance and the pathogenesis of nonalcoholic fatty liver disease Clin Liver Dis 8 2004 575 594
    • (2004) Clin Liver Dis , vol.8 , pp. 575-594
    • Choudhury, J.1    Sanyal, A.J.2
  • 8
    • 56649083495 scopus 로고    scopus 로고
    • Mechanisms of disease progression in nonalcoholic fatty liver disease
    • J. Jou, S.S. Choi, and A.M. Diehl Mechanisms of disease progression in nonalcoholic fatty liver disease Semin Liver Dis 28 2008 370 379
    • (2008) Semin Liver Dis , vol.28 , pp. 370-379
    • Jou, J.1    Choi, S.S.2    Diehl, A.M.3
  • 9
    • 0023801758 scopus 로고
    • Alcohol like liver disease in nonalcoholics. A clinical and histologic comparison with alcohol-induced liver injury
    • A.M. Diehl, Z. Goodman, and K.G. Ishak Alcohol like liver disease in nonalcoholics. A clinical and histologic comparison with alcohol-induced liver injury Gastroenterology 95 1988 1056 1062
    • (1988) Gastroenterology , vol.95 , pp. 1056-1062
    • Diehl, A.M.1    Goodman, Z.2    Ishak, K.G.3
  • 11
    • 67650901984 scopus 로고    scopus 로고
    • Pharmacological interventions for nonalcoholic fatty liver disease in adults and in children: A systematic review
    • P. Socha, A. Horvath, P. Vajro, P. Dziechciarz, A. Dhawan, and H. Szajewska Pharmacological interventions for nonalcoholic fatty liver disease in adults and in children: a systematic review J Pediatr Gastroenterol Nutr 48 2009 587 596
    • (2009) J Pediatr Gastroenterol Nutr , vol.48 , pp. 587-596
    • Socha, P.1    Horvath, A.2    Vajro, P.3    Dziechciarz, P.4    Dhawan, A.5    Szajewska, H.6
  • 12
    • 75449116707 scopus 로고    scopus 로고
    • Long-term efficacy of rosiglitazone in nonalcoholic steatohepatitis: Results of the fatty liver improvement by rosiglitazone therapy (FLIRT 2) extension trial
    • V. Ratziu, F. Charlotte, C. Bernhardt, P. Giral, M. Halbron, and G. Lenaour Long-term efficacy of rosiglitazone in nonalcoholic steatohepatitis: results of the fatty liver improvement by rosiglitazone therapy (FLIRT 2) extension trial Hepatology 51 2010 445 453
    • (2010) Hepatology , vol.51 , pp. 445-453
    • Ratziu, V.1    Charlotte, F.2    Bernhardt, C.3    Giral, P.4    Halbron, M.5    Lenaour, G.6
  • 13
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • N. Mizushima, B. Levine, A.M. Cuervo, and D.J. Klionsky Autophagy fights disease through cellular self-digestion Nature 451 2008 1069 1075
    • (2008) Nature , vol.451 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 14
    • 43949123866 scopus 로고    scopus 로고
    • Autophagy in the liver
    • X.M. Yin, W.X. Ding, and W. Gao Autophagy in the liver Hepatology 47 2008 1773 1785
    • (2008) Hepatology , vol.47 , pp. 1773-1785
    • Yin, X.M.1    Ding, W.X.2    Gao, W.3
  • 17
    • 77956400005 scopus 로고    scopus 로고
    • Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance
    • L. Yang, P. Li, S. Fu, E.S. Calay, and G.S. Hotamisligil Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance Cell Metab 11 2010 467 478
    • (2010) Cell Metab , vol.11 , pp. 467-478
    • Yang, L.1    Li, P.2    Fu, S.3    Calay, E.S.4    Hotamisligil, G.S.5
  • 18
    • 78049467743 scopus 로고    scopus 로고
    • Autophagy reduces acute ethanol-Induced hepatotoxicity and steatosis in mice
    • W.X. Ding, M. Li, X. Chen, H.M. Ni, C.W. Lin, and W. Gao Autophagy reduces acute ethanol-Induced hepatotoxicity and steatosis in mice Gastroenterology 139 2010 1740 1752
    • (2010) Gastroenterology , vol.139 , pp. 1740-1752
    • Ding, W.X.1    Li, M.2    Chen, X.3    Ni, H.M.4    Lin, C.W.5    Gao, W.6
  • 19
    • 78049236043 scopus 로고    scopus 로고
    • CYP2E1 enhances ethanol-induced lipid accumulation but impairs autophagy in HepG2 E47 cells
    • D. Wu, X. Wang, R. Zhou, and A. Cederbaum CYP2E1 enhances ethanol-induced lipid accumulation but impairs autophagy in HepG2 E47 cells Biochem Biophys Res Commun 402 2010 116 122
    • (2010) Biochem Biophys Res Commun , vol.402 , pp. 116-122
    • Wu, D.1    Wang, X.2    Zhou, R.3    Cederbaum, A.4
  • 20
    • 78650448754 scopus 로고    scopus 로고
    • Chemical modulators of autophagy as biological probes and potential therapeutics
    • A. Fleming, T. Noda, T. Yoshimori, and D.C. Rubinsztein Chemical modulators of autophagy as biological probes and potential therapeutics Nat Chem Biol 7 2011 9 17
    • (2011) Nat Chem Biol , vol.7 , pp. 9-17
    • Fleming, A.1    Noda, T.2    Yoshimori, T.3    Rubinsztein, D.C.4
  • 21
    • 46249115957 scopus 로고    scopus 로고
    • Autophagy activation by rapamycin eliminates mouse Mallory-Denk bodies and blocks their proteasome inhibitor-mediated formation
    • M. Harada, S. Hanada, D.M. Toivola, N. Ghori, and M.B. Omary Autophagy activation by rapamycin eliminates mouse Mallory-Denk bodies and blocks their proteasome inhibitor-mediated formation Hepatology 47 2008 2026 2035
    • (2008) Hepatology , vol.47 , pp. 2026-2035
    • Harada, M.1    Hanada, S.2    Toivola, D.M.3    Ghori, N.4    Omary, M.B.5
  • 22
    • 77954597127 scopus 로고    scopus 로고
    • An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis
    • T. Hidvegi, M. Ewing, P. Hale, C. Dippold, C. Beckett, and C. Kemp An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis Science 329 2010 229 232
    • (2010) Science , vol.329 , pp. 229-232
    • Hidvegi, T.1    Ewing, M.2    Hale, P.3    Dippold, C.4    Beckett, C.5    Kemp, C.6
  • 23
    • 33947497050 scopus 로고    scopus 로고
    • Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival
    • W.X. Ding, H.M. Ni, W. Gao, Y.F. Hou, M.A. Melan, and X. Chen Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival J Biol Chem 282 2007 4702 4710
    • (2007) J Biol Chem , vol.282 , pp. 4702-4710
    • Ding, W.X.1    Ni, H.M.2    Gao, W.3    Hou, Y.F.4    Melan, M.A.5    Chen, X.6
  • 24
    • 1542283812 scopus 로고    scopus 로고
    • In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
    • N. Mizushima, A. Yamamoto, M. Matsui, T. Yoshimori, and Y. Ohsumi In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker Mol Biol Cell 15 2004 1101 1111
    • (2004) Mol Biol Cell , vol.15 , pp. 1101-1111
    • Mizushima, N.1    Yamamoto, A.2    Matsui, M.3    Yoshimori, T.4    Ohsumi, Y.5
  • 25
    • 37749020003 scopus 로고    scopus 로고
    • Acute ethanol exposure inhibits insulin signaling in the liver
    • J. He, S. de la Monte, and J.R. Wands Acute ethanol exposure inhibits insulin signaling in the liver Hepatology 46 2007 1791 1800
    • (2007) Hepatology , vol.46 , pp. 1791-1800
    • He, J.1    De La Monte, S.2    Wands, J.R.3
  • 26
    • 0037047284 scopus 로고    scopus 로고
    • Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP)
    • M. You, M. Fischer, M.A. Deeg, and D.W. Crabb Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP) J Biol Chem 277 2002 29342 29347
    • (2002) J Biol Chem , vol.277 , pp. 29342-29347
    • You, M.1    Fischer, M.2    Deeg, M.A.3    Crabb, D.W.4
  • 28
    • 77956090723 scopus 로고    scopus 로고
    • Insulin assay standardization: Leading to measures of insulin sensitivity and secretion for practical clinical care: Response to Staten et al
    • author reply e84
    • L. Heinemann Insulin assay standardization: leading to measures of insulin sensitivity and secretion for practical clinical care: response to Staten et al Diabetes Care 33 2010 e83 author reply e84
    • (2010) Diabetes Care , vol.33 , pp. 83
    • Heinemann, L.1
  • 29
    • 79954576666 scopus 로고    scopus 로고
    • Hepatic FoxOs regulate lipid metabolism via modulation of expression of the nicotinamide phosphoribosyltransferase gene
    • R. Tao, D. Wei, H. Gao, Y. Liu, R.A. DePinho, and X.C. Dong Hepatic FoxOs regulate lipid metabolism via modulation of expression of the nicotinamide phosphoribosyltransferase gene J Biol Chem 286 2011 14681 14690
    • (2011) J Biol Chem , vol.286 , pp. 14681-14690
    • Tao, R.1    Wei, D.2    Gao, H.3    Liu, Y.4    Depinho, R.A.5    Dong, X.C.6
  • 31
    • 65649083316 scopus 로고    scopus 로고
    • Autophagy and ethanol-induced liver injury
    • T.M. Donohue Jr. Autophagy and ethanol-induced liver injury World J Gastroenterol 15 2009 1178 1185
    • (2009) World J Gastroenterol , vol.15 , pp. 1178-1185
    • Donohue, Jr.T.M.1
  • 32
    • 65549145048 scopus 로고    scopus 로고
    • An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1
    • C.C. Thoreen, S.A. Kang, J.W. Chang, Q. Liu, J. Zhang, and Y. Gao An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1 J Biol Chem 284 2009 8023 8032
    • (2009) J Biol Chem , vol.284 , pp. 8023-8032
    • Thoreen, C.C.1    Kang, S.A.2    Chang, J.W.3    Liu, Q.4    Zhang, J.5    Gao, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.