Essential role of D1R in the regulation of mTOR complex1 signaling induced by cocaine

Neuropharmacology

Volumn 99, Issue , 2015, Pages 610-619

  Sutton, Laurie P ^a   Caron, Marc G ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Cell signaling; Cocaine; Dopamine; mTOR; Nucleus accumbens; Raptor

Indexed keywords

6 CHLORO 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; COCAINE; DOPAMINE 1 RECEPTOR; INITIATION FACTOR 4E BINDING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; RACLOPRIDE; REGULATORY ASSOCIATED PROTEIN WITH MTOR; S6 KINASE; SERINE; THREONINE; UNCLASSIFIED DRUG; BENZAZEPINE DERIVATIVE; DOPAMINE RECEPTOR STIMULATING AGENT; DOPAMINE TRANSPORTER; DOPAMINE UPTAKE INHIBITOR; DRD1A PROTEIN, MOUSE; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MTOR PROTEIN, MOUSE; MULTIPROTEIN COMPLEX; RPTOR PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SK&F 81297; TARGET OF RAPAMYCIN KINASE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; GENE DELETION; KNOCKOUT MOUSE; LOCOMOTION; MALE; MOUSE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; DRUG EFFECTS; GENETICS; METABOLISM; MOTOR ACTIVITY; NERVE CELL; PHOSPHORYLATION; PHYSIOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BENZAZEPINES; COCAINE; DOPAMINE AGENTS; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINE UPTAKE INHIBITORS; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR ACTIVITY; MULTIPROTEIN COMPLEXES; NEURONS; NUCLEUS ACCUMBENS; PHOSPHORYLATION; RACLOPRIDE; RECEPTORS, DOPAMINE D1; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84940973020     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2015.08.024     Document Type: Article

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