Cell to cell spreading of misfolded proteins as a therapeutic target in motor neuron disease

Current Medicinal Chemistry

Volumn 21, Issue 31, 2014, Pages 3508-3534

  Pasquali, Livia ^a   Lenzi, Paola ^b   Biagioni, Francesca ^c   Siciliano, Gabriele ^a   Fornai, Francesco ^b,c  

^a Department of Clinical and Experimental Medicine ^*  (Italy)

^b UNIVERSITY OF PISA   (Italy)

^c IRCCS NEUROMED   (Italy)

Author keywords

Advanced glycation end products (AGEs); Amyotrophic lateral sclerosis (ALS); Autophagy; Misfolded proteins; Mitochondria; Prionoids; Renshaw cells; Stem cell therapy

Indexed keywords

ALSIN; COPPER ZINC SUPEROXIDE DISMUTASE; DYNACTIN; ESCRT PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; OPTINEURIN; PROTEIN AGGREGATE; TAR DNA BINDING PROTEIN; UNCLASSIFIED DRUG; ADVANCED GLYCATION END PRODUCT; PROTEIN;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; AUTOPHAGY; CELL SPREADING; CELL THERAPY; GENE MUTATION; GLIA; HUMAN; MITOCHONDRION; MOTOR NEURON DISEASE; NERVE CELL; NEUROPATHOLOGY; NONHUMAN; PROTEIN AGGREGATION; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; GENETICS; METABOLISM; MUTATION; PATHOLOGY; PROTEINOSIS; STEM CELL TRANSPLANTATION;

AUTOPHAGY; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMANS; MITOCHONDRIA; MOTOR NEURON DISEASE; MUTATION; NEURONS; PROTEIN AGGREGATION, PATHOLOGICAL; PROTEINS; STEM CELL TRANSPLANTATION;

EID: 84928660143     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/0929867321666140601161534     Document Type: Article

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