Advanced glycation endproduct-modified superoxide dismutase-1 (SOD1)-positive inclusions are common to familial amyotrophic lateral sclerosis patients with SOD1 gene mutations and transgenic mice expressing human SOD1 with a G85R mutation

Acta Neuropathologica

Volumn 100, Issue 5, 2000, Pages 490-505

  Kato, S ^a   Horiuchi, Seiko ^b   Liu, Jian ^c   Cleveland, Don W ^c   Shibata, Noriyuki ^d   Nakashima, Kenji ^a   Nagai, Ryoji ^b   Hirano, Asao ^e   Takikawa, Miki ^a   Kato, Masako ^f   Nakano, Imaharu ^g   Ohama, Eisaku ^a  

^a TOTTORI UNIVERSITY   (Japan)

^b KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

^c LUDWIG INSTITUTE FOR CANCER RESEARCH   (United States)

^d TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^e MONTEFIORE MEDICAL CENTER   (United States)

^f TOTTORI UNIVERSITY   (Japan)

^g JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Advanced glycation endproducts; Familial amyotrophic lateral sclerosis; G85R transgenic mice; Granule coated fibrils; Superoxide dismutase 1

Indexed keywords

3 NITROTYROSINE; 4 HYDROXYNONENAL; 6 N CARBOXYMETHYLLYSINE; ACROLEIN; ADVANCED GLYCATION END PRODUCT; ANTIBODY; HYALIN; NITRIC OXIDE SYNTHASE; PENTOSIDINE; SUPEROXIDE DISMUTASE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; CELL INCLUSION; CELL TYPE; CLINICAL ARTICLE; CONTROLLED STUDY; FAMILIAL DISEASE; FEMALE; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LEWY BODY; MALE; MOUSE; NERVE CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SOLUBILITY; TRANSGENIC MOUSE; ULTRASTRUCTURE;

ADULT; AGED; AGED, 80 AND OVER; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ARGININE; FEMALE; GLYCOSYLATION END PRODUCTS, ADVANCED; HISTOCYTOCHEMISTRY; HUMANS; IMMUNOHISTOCHEMISTRY; INCLUSION BODIES; LYSINE; MALE; MICE; MICE, TRANSGENIC; MICROSCOPY, ELECTRON; MICROSCOPY, IMMUNOELECTRON; MIDDLE AGED; MUTATION; NORLEUCINE; PYRROLES; SUPEROXIDE DISMUTASE;

EID: 0033823740     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004010000226     Document Type: Article

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