Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS

Experimental Neurology

Volumn 237, Issue 1, 2012, Pages 147-152

  Liao, Bing ^a,b,c   Zhao, Weihua ^b   Beers, David R ^b   Henkel, Jenny S ^b   Appel, Stanley H ^b  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b HOUSTON METHODIST HOSPITAL   (United States)

^c University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Amyotrophic lateral sclerosis; Microglia; Motor neurons; Neuroprotection; Neurotoxicity

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CD163 ANTIGEN; COPPER ZINC SUPEROXIDE DISMUTASE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CELL SURVIVAL; CELL TRANSFORMATION; COCULTURE; CONTROLLED STUDY; GENE OVEREXPRESSION; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; MICROGLIA; MOTONEURON; MOUSE; NERVE FIBER GROWTH; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ASTROCYTES; CELLS, CULTURED; COCULTURE TECHNIQUES; DISEASE MODELS, ANIMAL; HUMANS; INFLAMMATION; MICE; MICE, INBRED C57BL; MICE, NEUROLOGIC MUTANTS; MICE, TRANSGENIC; MICROGLIA; MOTOR NEURONS; PHENOTYPE; SUPEROXIDE DISMUTASE; TRANSFORMATION, GENETIC;

EID: 84863845583     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2012.06.011     Document Type: Article

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