Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 1, 2014, Pages 197-201

  Ivanova, Magdalena I ^a,b,c,d   Sievers, Stuart A ^a,b,c,e   Guenther, Elizabeth L ^a,b,c   Johnson, Lisa M ^a,b,c   Winkler, Duane D ^f,g   Galaleldeen, Ahmad ^g,h   Sawaya, Michael R ^a,b,c   Hart, P John ^f,i   Eisenberg, David S ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^e CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^f UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^g UNIVERSITY OF TEXAS AT DALLAS   (United States)

^h ST MARY'S UNIVERSITY   (United States)

ⁱ SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

Author keywords

Amyotrophic lateral sclerosis; Peptide structure; Protein aggregation

Indexed keywords

AMYLOID; COPPER ZINC SUPEROXIDE DISMUTASE; DOCUSATE CALCIUM; PROLINE;

AMINO ACID SEQUENCE; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CRYSTAL STRUCTURE; FAMILIAL AMYOTROPHIC LATERAL SCLEROSIS; HYDROGEN BOND; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PROCESSING; SPORADIC AMYOTROPHIC LATERAL SCLEROSIS; X RAY DIFFRACTION;

AMYOTROPHIC LATERAL SCLEROSIS; PEPTIDE STRUCTURE; PROTEIN AGGREGATION;

ALGORITHMS; AMINO ACID SEQUENCE; AMYOTROPHIC LATERAL SCLEROSIS; COMPUTER SIMULATION; HUMANS; METALS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDES; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; SUPEROXIDE DISMUTASE; TIME FACTORS;

EID: 84891959532     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1320786110     Document Type: Article

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