Enhancing mitochondrial calcium buffering capacity reduces aggregation of misfolded SOD1 and motor neuron cell death without extending survival in mouse models of inherited amyotrophic lateral sclerosis

Journal of Neuroscience

Volumn 33, Issue 11, 2013, Pages 4657-4671

  Parone, Philippe A ^a   Da Cruz, Sandrine ^a   Han, Joo Seok ^a   McAlonis Downes, Melissa ^a   Vetto, Anne P ^a   Lee, Sandra K ^a   Tseng, Eva ^a   Cleveland, Don W ^a  

^a LUDWIG INSTITUTE FOR CANCER RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM; CYCLOPHILIN D;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL TISSUE; ARTICLE; CELL DEATH; CONTROLLED STUDY; DISEASE COURSE; ELECTRON MICROSCOPY; FEMALE; GEL PERMEATION CHROMATOGRAPHY; GLIA CELL; GRIP STRENGTH; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; MALE; MITOCHONDRIAL PERMEABILITY; MITOCHONDRION; MITOCHONDRION SWELLING; MORPHOMETRICS; MOTONEURON; MOUSE; MUSCLE DENERVATION; NERVE FIBER DEGENERATION; NEUROMUSCULAR SYNAPSE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL;

ADENOSINE TRIPHOSPHATE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ANTIBODIES; AXONS; CALCIUM; CALCIUM-BINDING PROTEINS; CELL DEATH; CHROMATOGRAPHY, GEL; CYCLOPHILINS; DISEASE MODELS, ANIMAL; GLIAL FIBRILLARY ACIDIC PROTEIN; HAND STRENGTH; HUMANS; IMMUNOPRECIPITATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROFILAMENT PROTEINS; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; MOTOR NEURONS; MUTATION; NEUROMUSCULAR JUNCTION; SUPEROXIDE DISMUTASE;

EID: 84874914445     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1119-12.2013     Document Type: Article

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